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DHH (NM_021044) Human Untagged Clone
CAT＃: SC122903
DHH (untagged)-Human desert hedgehog (DHH)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GDMN; GDXYM; HHG-3; SRXY7 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_021044 edited
GTCCGGAGTCCGGGCGTTCTGGCAGCACCAGAGTCCTGCAGCAGAGACGGGCTGGGCTGG CACTCACCCACGACCCCCCTTCCCTGCTATGATGGTTTGTCAGTAGCAGGTCCTAGACAC CCCCCGCCCGCTCCCGGGGCACGTGGGCAGAGCTAGCAGCAGCCAGGTGCACGGAGCCAC AAGAGCTCTAGGGCACTCTGGGGGCAGCTGTGCCTGCTGCCCTCTCTGGTGCCTGTGGAG ATGCCTAACTGACAGGAGAGTTAGTGAGGACAAGAACGCTCCCTTTTGGCCGAGGTCCGC TGTATCCATGGCTCTCCTGACCAATCTACTGCCCCTGTGCTGCTTGGCACTTCTGGCGCT GCCAGCCCAGAGCTGCGGGCCGGGCCGGGGGCCGGTTGGCCGGCGCCGCTATGCGCGCAA GCAGCTCGTGCCGCTACTCTACAAGCAATTTGTGCCCGGCGTGCCAGAGCGGACCCTGGG CGCCAGTGGGCCAGCGGAGGGGAGGGTGGCAAGGGGCTCCGAGCGCTTCCGGGACCTCGT GCCCAACTACAACCCCGACATCATCTTCAAGGATGAGGAGAACAGTGGAGCCGACCGCCT GATGACCGAGCGTTGTAAGGAGCGGGTGAACGCTTTGGCCATTGCCGTGATGAACATGTG GCCCGGAGTGCGCCTACGAGTGACTGAGGGCTGGGACGAGGACGGCCACCACGCTCAGGA TTCACTCCACTACGAAGGCCGTGCTTTGGACATCACTACGTCTGACCGCGACCGCAACAA GTATGGGTTGCTGGCGCGCCTCGCAGTGGAAGCCGGCTTCGACTGGGTCTACTACGAGTC CCGCAACCACGTCCACGTGTCGGTCAAAGCTGATAACTCACTGGCGGTCCGGGCGGGCGG CTGCTTTCCGGGAAATGCAACTGTGCGCCTGTGGAGCGGCGAGCGGAAAGGGCTGCGGGA ACTGCACCGCGGAGACTGGGTTTTGGCGGCCGATGCGTCAGGCCGGGTGGTGCCCACGCC GGTGCTGCTCTTCCTGGACCGGGACTTGCAGCGCCGGGCTTCATTTGTGGCTGTGGAGAC CGAGTGGCCTCCACGCAAACTGTTGCTCACGCCCTGGCACCTGGTGTTTGCCGCTCGAGG GCCGGCGCCCGCGCCAGGCGACTTTGCACCGGTGTTCGCGCGCCGGCTACGCGCTGGGGA CTCGGTGCTGGCGCCCGGCGGGGATGCGCTTCGGCCAGCGCGCGTGGCCCGTGTGGCGCG GGAGGAAGCCGTGGGCGTGTTCGCGCCGCTCACCGCGCACGGGACGCTGCTGGTGAACGA TGTCCTGGCCTCTTGCTACGCGGTTCTGGAGAGTCACCAGTGGGCGCACCGCGCTTTTGC CCCCTTGAGACTGCTGCACGCGCTAGGGGCGCTGCTCCCCGGCGGGGCCGTCCAGCCGAC TGGCATGCATTGGTACTCTCGGCTCCTCTACCGCTTAGCGGAGGAGCTACTGGGCTGAGC GTCCCAGGCATAGAAACCTCGAAGCGCCCGAGGAAACGAGGGCCTGCTGGCTGAGATATG GGGCTGTGGGCAGCAGACGATGCCGACTGGAAGGGAGGGAGAGGGAGGGGGAGGGAGAAA ATGGGGCTATGCCTGGCTTAGGGGCAACCTCGTACTGAGAGGAGGTGATACCGGGTCCTA GGTAGGTAGGGCTGATGGTGCGCACTCCTTAAAGAGGACTATTTAGCCTCTCCCCCAGTG CTTCAGCCCCACCCGATAATTTTATTTTATTTCTTATTTATAAATTGTAATATAATGATT CCCTTGCCCAGCTTGCCAAGGTGAGGGGCTGGGGCATGGCATTAACACTGTCTGACACAG CCAGCCAGTCTGACATCTGACGTTTTCCTGCAAGGTGGGCTAATAAAGGGAAGGCTTTCA GGAGCTTACTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_021044 unedited
GTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATCCCGGGNTGTCCGGAGTCCGG GCGTTCTGGCAGCACCAGAGTCCTGCAGCAGAGACGGGCTGGGCTGGCACTCACCCACGA CCCCCCTTCCCTGCTATGATGGTTTGTCAGTAGCAGGTCCTAGACACCCCCCGCCCGCTC CCGGGGCACGTGGGCAGAGCTAGCAGCAGCCAGGTGCACGGAGCCACAAGAGCTCTAGGG CACTCTGGGGGCAGCTGTGCCTGCTGCCCTCTCTGGTGCCTGTGGAGATGCCTAACTGAC AGGAGAGTTAGTGAGGACAAGAACGCTCCCTTTTGGCCGAGGTCCGCTGTATCCATGGCT CTCCTGACCAATCTACTGCCCCTGTGCTGCTTGGCACTTCTGGCGCTGCCAGCCCAGAGC TGCGGGCCGGGCCGGGGGCCGGTTGGCCGGCGCCGCTATGCGCGCAAGCAGCTCGTGCCG CTACTCTACAAGCAATTTGTGCCCGGCGTGCCAGAGCGGACCCTGGGCGCCAGTGGGCCA GCGGAGGGGAGGGTGGCAAGGGGCTCCGAGCGCTTCCGGGACCTCGTGCCCAACTACAAC CCCGACATCATCTTCAAGGATGAGGAGAACAGTGGAGCCGACCGCCTGATGACCGAGCGT TGTAAGGAGCGGGTGAACGCTTTGGCCATTGCCGTGATGAACATGTGGCCCGGAGTGCGC CTACNAGTGACTGAGGGCTGGGACGAGGACGGCCACACGCTCAGGATCACTCACTACGAA GCCGTGCCTTGGANTCACTACTTCTGACCGCGACGCAACAGTATGGGTTGCTGGCGCGCC TCCAATGAAAGCCGCTTCCACTGGGTTACTACAAGTCCGAACCACGTCCAGTGTCGGTCA AGCTGAAACTCACTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_021044 |
| Insert Size | 1971 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021044.2, NP_066382.1 |
| RefSeq Size | 1971 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 50846 |
| UniProt ID | O43323 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease |
| Protein Pathways | Hedgehog signaling pathway |
| Gene Summary | This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Loss of Function Mutation in the Palmitoyl-Transferase HHAT Leads to Syndromic 46,XY Disorder of Sex Development by Impeding Hedgehog Protein Palmitoylation and Signaling
,Callier, P;Calvel, P;Matevossian, A;Makrythanasis, P;Bernard, P;Kurosaka, H;Vannier, A;Thauvin-Robinet, C;Borel, C;Mazaud-Guittot, S;Rolland, A;Desdoits-Lethimonier, C;Guipponi, M;Zimmermann, C;Stévant, I;Kuhne, F;Conne, B;Santoni, F;Lambert, S;Huet, F;Mu,
PLoS Genet.
,PubMed ID 24784881
[DHH]
|
|
In Vitro and Molecular Modeling Analysis of Two Mutant Desert Hedgehog Proteins Associated with 46,XY Gonadal Dysgenesis
,null,
DNA and Cell Biology
,PubMed ID 23786321
[DHH]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206715 | DHH (Myc-DDK-tagged)-Human desert hedgehog (DHH) |
CNY 3,656.00 |
|
| RC206715L1 | Lenti ORF clone of Human desert hedgehog (DHH), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206715L2 | Lenti ORF clone of Human desert hedgehog (DHH), mGFP tagged |
CNY 5,890.00 |
|
| RC206715L3 | Lenti ORF clone of Human desert hedgehog (DHH), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206715L4 | Lenti ORF clone of Human desert hedgehog (DHH), mGFP tagged |
CNY 5,890.00 |
|
| RG206715 | DHH (tGFP-tagged) - Human desert hedgehog (DHH) |
CNY 4,370.00 |
