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RIN1 (NM_004292) Human Untagged Clone
CAT＃: SC122674
RIN1 (untagged)-Human Ras and Rab interactor 1 (RIN1)
CNY 5,744.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004292 edited
CGAAGGAGCTCCCAGCCATGGAAAGCCCTGGAGAGTCAGGCGCGGGCTCTCCTGGAGCCC CCAGCCCGTCCAGCTTCACTACTGGGCACCTGGCGAGAGAAAAGCCAGCCCAGGACCCAC TGTATGACGTGCCCAATGCCAGCGGCGGGCAGGCAGGCGGGCCGCAGCGGCCGGGGCGCG TTGTGAGCCTGCGGGAGCGCCTGCTGCTCACCCGGCCCGTGTGGCTGCAGCTGCAAGCCA ACGCAGCGGCCGCACTGCACATGCTGAGGACCGAGCCCCCGGGGACGTTCCTCGTGCGGA AATCTAACACCCGCCAGTGCCAGGCCCTGTGCATGCGGTTGCCTGAAGCCAGTGGCCCCT CCTTCGTCTCCAGCCACTACATCCTGGAGAGCCCTGGCGGCGTCTCCTTGGAGGGCTCGG AGCTCATGTTCCCAGACCTAGTCCAGCTCATCTGTGCCTACTGCCACACCCGGGACATCC TTCTCCTCCCGCTGCAGCTCCCCAGAGCCATCCACCACGCAGCCACTCACAAAGAGCTGG AGGCCATCTCCCATCTGGGCATTGAGTTCTGGAGCTCCTCCCTCAACATCAAGGCTCAGC GGGGCCCGGCTGGAGGCCCAGTGTTGCCCCAGCTGAAGGCCCGGTCCCCTCAAGAGCTGG ACCAGGGCACCGGAGCCGCCTTGTGCTTCTTCAACCCCCTGTTCCCGGGGGACCTAGGGC CCACCAAGCGGGAGAAATTCAAGAGAAGCTTCAAAGTGCGCGTGTCCACAGAGACCTCCA GCCCCCTGTCTCCACCTGCCGTGCCACCTCCCCCCGTCCCCGTGCTGCCAGGGGCAGTCC CCAGCCAGACAGAGCGGCTGCCCCCTTGCCAGCTGCTACGGAGGGAGAGCTCAGTGGGGT ACCGCGTGCCAGCAGGCAGTGGCCCTAGCCTTCCGCCTATGCCCTCCCTCCAAGAGGTGG ACTGCGGCTCCCCCAGCAGCTCCGAGGAGGAGGGGGTGCCAGGGTCCCGGGGGAGCCCAG CGACCTCACCCCACCTGGGCCGCCGACGACCTCTGCTTCGGTCCATGAGCGCCGCCTTCT GCTCCCTACTGGCACCGGAGCGGCAGGTGGGCCGGGCTGCGGCAGCACTGATGCAGGACC GACACACAGCCGCGGGCCAGCTGGTGCAGGACCTACTGACCCAGGTGCGGGCTGGGCCCG AGCCCCAGGAGCTGCAGGGCATCCGTCAGGCGCTGAGCCGGGCCCGGGCCATGCTGAGTG CGGAGCTGGGCCCTGAGAAGCTGCTGTCGCCTAAGAGGCTGGAACATGTCCTGGAGAAGT CATTGCATTGCTCTGTGCTCAAGCCTCTCCGGCCCATCCTGGCAGCCCGCCTGCGGCGCC GGCTTGCCGCAGACGGCTCCCTGGGCCGCCTAGCTGAGGGCCTCCGCCTGGCCCGGGCCC AGGGCCCCGGAGCCTTCGGGTCCCACCTGAGCCTGCCCTCCCCAGTAGAGTTGGAGCAAG TGCGCCAGAAGCTGCTGCAGCTGCTCCGCACCTACTCACCCAGCGCCCAGGTCAAGCGGC TCCTGCAGGCCTGCAAGCTGCTCTACATGGCCCTGAGGACCCAGGAAGGGGAGGGCGCGG GTGCCGACGAGTTCCTGCCTCTGCTGAGCCTCGTCTTGGCCCACTGTGACCTTCCTGAGC TGCTGCTGGAGGCCGAGTACATGTCGGAGCTGCTGGAGCCCAGCCTGCTTACTGGAGAGG GTGGCTACTACCTGACCAGCCTCTCTGCCAGCCTGGCCCTGCTGAGTGGCCTGGGTCAGG CCCACACCCTCCCACTGAGCCCCGTGCAGGAGCTACGGCGCTCCCTCAGCCTCTGGGAGC AGCGCCGCCTGCCTGCCACCCACTGCTTCCAGCACCTCCTCCGAGTAGCCTATCAGGATC CCAGCAGTGGCTGCACCTCCAAGACCCTGGCCGTGCCCCCAGAGGCCTCGATTGCCACCC TGAACCAGCTCTGTGCCACCAAGTTCCGAGTGACCCAGCCCAACACTTTTGGCCTCTTCC TGTACAAGGAGCAGGGCTACCACCGCCTGCCCCCTGGGGCCCTGGCCCACAGGCTGCCCA CCACTGGCTACCTCGTCTACCGCCGGGCAGAGTGGCCTGAGACCCAGGGGGCTGTGACAG AGGAGGAGGGCAGTGGGCAGTCAGAGGCAAGAAGCAGAGGGGAGGAGCAAGGGTGCCAGG GAGATGGGGATGCTGGGGTCAAAGCCAGCCCCAGGGACATTCGGGAACAGTCTGAGACAA CTGCTGAAGGGGGCCAGGGTCAAGCCCAGGAAGGCCCTGCTCAGCCAGGGGAACCAGAGG CAGAGGGAAGCCGGGCAGCAGAGGAGTAGCTTGAAGTGGCCAGAAGGGTCATTCGGGGCG GGAGACCCTGAGCCTGCTGAGAAATCCTTTTAGCGCCAGCAAGCCCCACCCAGGGCCCTG TCCTGTGTCTGCCACCACCTTTGTCTGATACTTGTTTCCAGGGAAGCTGGGGGAACTGCC ACATCTGAGGAACTGGAATAAAGATGAGGGGGCTTCGGGGGCCCCCAGACTGTGAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_004292 unedited
NNAAAGTACAAATTTTGTAATACGACTCACTATAGGGCACGGCCGCGAATTCGCACGAGG CGAAGGAGCTCCCAGCCATGGAAAGCCCTGGAGAGTCAGGCGCGGGCTCTCCTGGAGCCC CCAGCCCGTCCAGCTTCACTACTGGGCACCTGGCGAGAGAAAAGCCAGCCCAGGACCCAC TGTATGACGTGCCCAATGCCAGCGGCGGGCAGGCAGGCGGGCCGCAGCGGCCGGGGCGCG TTGTGAGCCTGCGGGAGCGCCTGCTGCTCACCCGGCCCGTGTGGCTGCAGCTGCAAGCCA ACGCAGCGGCCGCACTGCACATGCTGAGGACCGAGCCCCCGGGGACGTTCCTCGTGCGGA AATCTAACACCCGCCAGTGCCAGGCCCTGTGCATGCGGTTGCCTGAAGCCAGTGGCCCCT CCTTCGTCTCCAGCCACTACATCCTGGAGAGCCCTGGCGGCGTCTCCTTGGAGGGCTCGG AGCTCATGTTCCCAGACCTAGTCCAGCTCATCTGTGCCTACTGCCACACCCGGGACATCC TTCTCCTCCCGCTGCAGCTCCCCAGAGCCATCCACCACGCAGCCACTCACAAAGAGCTGG AGGCCATCTCCCATCTGGGCATTGAGTTCTGGAGCTCCTCCCTCAACATCAAGGCTCAGC GGGGCCCGGCTGGAGGCCCAGTGTTGCCCCAGCTGAAGGCCCGGTCCCCTCAAGAGCTGG ACCAGGGCACCGGAGCCGCCTTGTGCTTCTTCAACCCCCTGTTCCCGGGGGACCTAGGGC CCACCAAGCGGGAGAAATTCAAGAAAGCTTCAAAGTGCGCGTGTCCACAGAGACCTCCAC CCCCTGTCTCCACTGCCGTGCCACTCCCCCGTCCCGTGCTGCCAGGGGCC |
| Restriction Sites | Please inquire |
| ACCN | NM_004292 |
| Insert Size | 2634 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004292.2, NP_004283.2 |
| RefSeq Size | 2698 bp |
| RefSeq ORF | 2352 bp |
| Locus ID | 9610 |
| UniProt ID | Q13671 |
| Gene Summary | Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.[UniProtKB/Swiss-Prot Function] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-ß-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration
,Gerarduzzi, C;He, Q;Zhai, B;Antoniou, J;Di Battista, JA;,
J. Cell. Physiol.
,PubMed ID 27137893
[RIN1]
|
|
The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.
,null,
Science signaling
,PubMed ID 25690013
[RIN1]
|
|
Quantitative Phosphoproteomic Analysis of Signaling Downstream of the Prostaglandin E2/G-protein Coupled Receptor in Human Synovial Fibroblasts: Potential Antifibrotic Networks
,Gerarduzzi, C;He, Q;Antoniou, J;Di Battista, JA;,
J. Proteome Res.
,PubMed ID 25223752
[Rin1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204147 | RIN1 (Myc-DDK-tagged)-Human Ras and Rab interactor 1 (RIN1) |
CNY 5,800.00 |
|
| RC204147L3 | Lenti-ORF clone of RIN1 (Myc-DDK-tagged)-Human Ras and Rab interactor 1 (RIN1) |
CNY 7,700.00 |
|
| RC204147L4 | Lenti-ORF clone of RIN1 (mGFP-tagged)-Human Ras and Rab interactor 1 (RIN1) |
CNY 7,700.00 |
|
| RG204147 | RIN1 (tGFP-tagged) - Human Ras and Rab interactor 1 (RIN1) |
CNY 6,370.00 |
