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Myocilin (MYOC) (NM_000261) Human Untagged Clone
CAT＃: SC122555
MYOC (untagged)-Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC)
CNY 5,640.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GLC1A; GPOA; JOAG; JOAG1; TIGR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000261 edited
CATCCAGGCACCTCTCAGCACAGCAGAGCTTTCCAGAGGAAGCCTCACCAAGCCTCTGCA ATGAGGTTCTTCTGTGCACGTTGCTGCAGCTTTGGGCCTGAGATGCCAGCTGTCCAGCTG CTGCTTCTGGCCTGCCTGGTGTGGGATGTGGGGGCCAGGACAGCTCAGCTCAGGAAGGCC AATGACCAGAGTGGCCGATGCCAGTATACCTTCAGTGTGGCCAGTCCCAATGAATCCAGC TGCCCAGAGCAGAGCCAGGCCATGTCAGTCATCCATAACTTACAGAGAGACAGCAGCACC CAACGCTTAGACCTGGAGGCCACCAAAGCTCGACTCAGCTCCCTGGAGAGCCTCCTCCAC CAATTGACCTTGGACCAGGCTGCCAGGCCCCAGGAGACCCAGGAGGGGCTGCAGAGGGAG CTGGGCACCCTGAGGCGGGAGCGGGACCAGCTGGAAACCCAAACCAGAGAGTTGGAGACT GCCTACAGCAACCTCCTCCGAGACAAGTCAGTTCTGGAGGAAGAGAAGAAGCGACTAAGG CAAGAAAATGAGAATCTGGCCAGGAGGTTGGAAAGCAGCAGCCAGGAGGTAGCAAGGCTG AGAAGGGGCCAGTGTCCCCAGACCCGAGACACTGCTCGGGCTGTGCCACCAGGCTCCAGA GAAGTTTCTACGTGGAATTTGGACACTTTGGCCTTCCAGGAACTGAAGTCCGAGCTAACT GAAGTTCCTGCTTCCCGAATTTTGAAGGAGAGCCCATCTGGCTATCTCAGGAGTGGAGAG GGAGACACCGGATGTGGAGAACTAGTTTGGGTAGGAGAGCCTCTCACGCTGAGAACAGCA GAAACAATTACTGGCAAGTATGGTGTGTGGATGCGAGACCCCAAGCCCACCTACCCCTAC ACCCAGGAGACCACGTGGAGAATCGACACAGTTGGCACGGATGTCCGCCAGGTTTTTGAG TATGACCTCATCAGCCAGTTTATGCAGGGCTACCCTTCTAAGGTTCACATACTGCCTAGG CCACTGGAAAGCACGGGTGCTGTGGTGTACTCGGGGAGCCTCTATTTCCAGGGCGCTGAG TCCAGAACTGTCATAAGATATGAGCTGAATACCGAGACAGTGAAGGCTGAGAAGGAAATC CCTGGAGCTGGCTACCACGGACAGTTCCCGTATTCTTGGGGTGGCTACACGGACATTGAC TTGGCTGTGGATGAAGCAGGCCTCTGGGTCATTTACAGCACCGATGAGGCCAAAGGTGCC ATTGTCCTCTCCAAACTGAACCCAGAGAATCTGGAACTCGAACAAACCTGGGAGACAAAC ATCCGTAAGCAGTCAGTCGCCAATGCCTTCATCATCTGTGGCACCTTGTACACCGTCAGC AGCTACACCTCAGCAGATGCTACCGTCAACTTTGCTTATGACACAGGCACAGGTATCAGC AAGACCCTGACCATCCCATTCAAGAACCGCTATAAGTACAGCAGCATGATTGACTACAAC CCCCTGGAGAAGAAGCTCTTTGCCTGGGACAACTTGAACATGGTCACTTATGACATCAAG CTCTCCAAGATGTGAAAAGCCTCCAAGCTGTACAGGCAATGGCAGAAGGAGATGCTCAGG GCTCCTGGGGGGAGCAGGCTGAAGGGAGAGCCAGCCAGCCAGGGCCCAGGCAGCTTTGAC TGCTTTCCAAGTTTTCATTAATCCAGAAGGATGAACATGGTCACCATCTAACTATTCAGG AATTGTAGTCTGAGGGCGTAGACAATTTCATATAATAAATATCCTTTATCTTCTGTCAGC ATTTATGGGATGTTTAATGACATAGTTCAAGTTTTCTTGTGATTTGGGGCAAAAGCTGTA AGGCATAATAGTTTCTTCCTGAAAACCATTGCTCTTGCATGTTACATGGTTACCACAAGC CACAATAAAAAGCATAACTTCTAAAGGAAGCAGAATAGCTCCTCTGGCCAGCATCGAATA TAAGTAAGATGCATTTACTACAGTTGGCTTCTAATGCTTCAGATAGAATACAGTTGGGTC TCACATAACCCTTTACATTGTGAAATAAAATTTTCTTACCCAAAAAAAAAAAAAAAAAAA AAAAAAAAAAA >OriGene 5' read for NM_000261 unedited
NAAAATGTTTGNNATTTTTGTNAATACGACTTCACTATAGGGACGGGCCGCGNAATTCCC GGGCATCATCCAGCACCTCTCAGCACAGCATATCTTTCCAGAGGAAGCCTCACCAAGCCT CTGCAATGAGGTTCTTCTGTGCACGTTGCTGCAGCTTTGGGCCTGAGATGCCAGCTGTCC AGCTGCTGCTTCTGGCCTGCCTGGTGTGGGATGTGGGGGCCAGGACAGCTCAGCTCATGA AGGCCAATGACCAGAGTGGCCGATGCCAGTATACCTTCAGTGTGGCCAGTCCCAATGAAT CCAGCTGCCCAGAGCAGAGCCAGGCCATGTCAGTCATCCATAACTTACAGAGAGACAGCA GCACCCAACGCTTAGACCTGGAGGCCACCAAAGCTCGACTCAGCTCCCTGGAGAGCCTCC TCCACCAATTGACCTTGGACCAGGCTGCCAGGCCCCAGGAGACCCAGGAGGGGCTGCAGA GGGAGCTGGGCACCCTGAGGCGGGAGCGGGACCAGCTGGAAACCCAAACCAGAGAGTTGG AGACTGCCTACAGCAACCTCCTCCGAGACAAGTCAGTTCTGGAGGAAGAGAAGAAGCGAC TAAGGCAAGAAAATGAGAATCTGGCCAGGAGGTTGGAAAGCAGCAGCCAGGAAGTAGCAA GGCTGAGAAGGGGCCAGTGTCCCCAGACCCGAGACACTGCTCGGGCTGTGCCACCAGGCT CCAGAGAAGTTTCTACGTGGAATTTGGACACTTTGGCCTTCCAGGAACTGAAGTCCGAGC TAACTGAAGTTCCCTGCTTCCCGATTTTGAAGGAGAGCCCATCTGGCTATCNTCAGAGTG GGAAAGGAGACACCGGATGTGGAGAACTANTTTGGGGTTAAGAAAGCTCTNACGCTGAGA CAGCAGAAACATACTGCAGTTTNGGGGGTGGGGATC |
| Restriction Sites | Please inquire |
| ACCN | NM_000261 |
| Insert Size | 2111 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000261.1, NP_000252.1 |
| RefSeq Size | 2061 bp |
| RefSeq ORF | 1515 bp |
| Locus ID | 4653 |
| UniProt ID | Q99972 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206556 | MYOC (Myc-DDK-tagged)-Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) |
CNY 5,632.00 |
|
| RC206556L1 | Lenti ORF clone of Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), Myc-DDK-tagged |
CNY 8,032.00 |
|
| RC206556L2 | Lenti ORF clone of Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), mGFP tagged |
CNY 6,460.00 |
|
| RC206556L3 | Lenti ORF clone of Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC206556L4 | Lenti ORF clone of Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), mGFP tagged |
CNY 6,460.00 |
|
| RG206556 | MYOC (tGFP-tagged) - Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) |
CNY 7,232.00 |
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