FYCO1 (BC007218) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	DKFZp779K1152; FLJ13335; FYVE and coiled-coil domain containing 1; MGC126517; MGC126519; OTTHUMP00000164650; RUFY3; RUN and FYVE domain containing 3; ZFYVE7
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC007218 edited CCAGCTTGCATAAATTTTCTTATAAACTTGAGTATCTCCTGCAATTTGATCAGAAAGAGA AGGCCACCCTCCTGGGCAACAAGAAGGACTACTGGGATTACTTCTGTGCCTGCCTGGCCA AGGTGAAAGGAGCCAATGATGGGATCCGATTTGTCAAGTCTATCTCAGAGCTCCGAACAT CCTTGGGGAAAGGAAGAGCATTTATTCGCTACTCCTTGGTGCACCAGAGGTTGGCAGACA CCTTACAGCAGTGCTTCATGAACACCAAAGTGACCAGTGACTGGTACTATGCAAGAAGCC CCTTTCTGCAGCCAAAGCTGAGCTCGGACATTGTGGGCCAACTCTATGAGCTGACTGAGG TTCAGTTTGACCTGGCGTCGAGGGGCTTTGACTTGGATGCTGCCTGGCCAACATTTGCCA GGAGGACGCTGACCACTGGCTCTTCTGCTTACCTGTGGAAACCCCCTAGCCGCAGCTCCA GCATGAGCAGCTTGGTGAGCAGCTACCTGCAGACTCAAGAGATGGTGTCCAACTTTGACC TGAACAGCCCCCTAAACAACGAGGCATTGGAGGGCTTTGATGAGATGCGACTAGAGCTGG ACCAGTTGGAGGTGCGGGAGAAGCAGCTACAGGAGCGCATGCAGCAGCTGGACAGAGAGA ACCAGGAGCTGAGGGCAGCTGTCAGCCAGCAAGGGGAGCAACTGCAGACAGAGAGGGAGA GGGGGCGCACTGCAGCGGAGGACAACGTTCGCCTCACTTGCTTGGTAGCTGAGCTCCAGA AGCAGTGGGAGGTCACCCAGGCCACCCAGAACACTGTGAAGGAGCTGCAGACATGCCTGC AGGCCCTGGAGCTAGGAGCAGCAGAGAAGGAGGAGGACTACCACACAGCCCTGCGGCGGC TGGAGTCCATGCTGCAGCCCTTGGCACAGGAGCTTGAGGCCACACGGGACTCACTGGACA AGAAAAACCAGCATTTAGCCAGCTTCCCAGGCTGGCTAGCCATGGCCCTGCATGTTGGAG ACTGAGCTGGGTGCACTGGCCATGCCCTGTGAATCCTCGGGCTGTGACGCCCTCAGGTAC TCCTGGGAAAAGGAGGTACACAGCCATCGTGCGAGTCGGTGCCAGGGGACCCCCCGGAGA TCCTGACCAGCTCCTCCAGTCATGCTCTTGTCCCTCACTGCCCCAGTAAGCTGGAGGCTG CTCCAGAACTCAGCAGTGTTGGAGGGGCCTCTAAGCTGCACTCTCTTTCTGGCCCTTTTG TCTGGCTGATTCTGTCCTCAAATAAAGCCCTTCACTCAGCCAGACCTCTCCACAGCTCAA AGCATTGCCCTAAGAATCAGAAGTAAAGATAATCCAAGAGCAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC007218 unedited NNNGGCAGTTCAAATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCCA GCTTGCATAAATTTTCTTATAAACTTGAGTATCTCCTGCAATTTGATCAGAAAGAGAAGG CCACCCTCCTGGGCAACAAGAAGGACTACTGGGATTACTTCTGTGCCTGCCTGGCCAAGG TGAAAGGAGCCAATGATGGGATCCGATTTGTCAAGTCTATCTCAGAGCTCCGAACATCCT TGGGGAAAGGAAGAGCATTTATTCGCTACTCCTTGGTGCACCAGAGGTTGGCAGACACCT TACAGCAGTGCTTCATGAACACCAAAGTGACCAGTGACTGGTACTATGCAAGAAGCCCCT TTCTGCAGCCAAAGCTGAGCTCGGACATTGTGGGCCAACTCTATGAGCTGACTGAGGTTC AGTTTGACCTGGCGTCGAGGGGCTTTGACTTGGATGCTGCCTGGCCAACATTTGCCAGGA GGACGCTGACCACTGGCTCTTCTGCTTACCTGTGGAAACCCCCTAGCCGCAGCTCCAGCA TGAGCAGCTTGGTGAGCAGCTACCTGCAGACTCAAGAGATGGTGTCCAACTTTGACCTGA ACAGCCCCCTAAACAACGAGGCATTGGAGGGCTTTGATGAGATGCGACTAGAGCTGGACC AGTTGGAGGTGCGGGAGAAGCAGCTACAGGAGCGCATGCAGCAGCTGGACAGAGAGAACC AGGAGCTGAGGGCAGCTGTCAGCCAGCAAGGGGAGCAACTGCANACAGAGAGGGAGAGGG GGCGCACTGCAGNCGGAGACAACGTTCGCCTCACTTGCTTGGTAGCTGAGCTCCAGAAGC AGTGGGGAGTCACCCAGGCCACCCAAACACTGTGAAAGAGCTGC
Restriction Sites	Please inquire
ACCN	BC007218
Insert Size	1398 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC007218.1, AAH07218.1
RefSeq Size	1398 bp
Locus ID	79443
Gene Summary	The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020]

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