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E2F2 (BC007609) Human Untagged Clone
CAT＃: SC122267
E2F2 (untagged)-Homo sapiens, Similar to hypothetical protein PRO1722, clone MGC:15692 IMAGE:3351479, complete cds
CNY 8,712.00
CNY 9,120.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | E2F-2; E2F transcription factor 2; OTTHUMP00000003257 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for BC007609 edited
CTAGAATGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTT TGCCTCTTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTG GTCGCCTCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCT CCTGTGGAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCT CCCCTTGAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGC ATGGGGGCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTG GTCCAGGAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAG GGTCAGATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGC ATCATTCTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCAT TAAGGACTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGG TGACTTGTTCACTCCTTTTTTCCCAGGTATACTGAAGGGGTGACAGAGAGAGGTCTTCAT GGCAGACCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGG GGTCCTGAGGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAGGCTTGATCATCCCACATT GTCCCTTCAGCTCAGCTGCTCTTCTCCCCCACCCACCCTGGGATGTGGGTGCTCTGGGCT GAACCAAGGCTATGACTTCTGGAGAGAGGCTCAGGGGTTGGTCTGAGAGGCCTGCCATCC ACCCCTCAGGGAGCTAGGTTTTCTCAGAGGCTCAGCTGGACAGCACTTTTTAGAAAAGTT TGTAGCATTAAGCTGGTTTAAAATATGAAGTTGGTTTTGTTGGATGGCTCCTGAGCTGAC TGACTGATGTCTGAAGTTTGAGACGAGGGATTATTTCAGGGTGGGGCCCAATGTGATCTA ATGCCCAGCTGGGGACAATTGTGCCTCATCATTTGCTCAAATTCCTGGGCCCCCAAGTTA GCCCCCTCCCAGGAGTGGTCAGCGGGTCACAGCTGCCCCCACTCTATAAGCAGGGCTAAT TGTGTACCCTTTGCAGAAATGCTTTTGGTCTCCTACCCAAATACTCACAAGGGTCTTATC AGACGCCCGTCTTAAAGTCCAGCATGCTCAGGGACCCTGTGTAGGATCTCGTTTGTGGTG AGTGGGCTGCTCTGAGGTCTCCACTGGGCTGCCATTTAGCCATGTGCCATCTCTGAAGTC AGAGGTGTTTGACTCCCATTCCTTGGGCTCTGGAGCTTTCCCCAAGAATTACATCAGAGA AAAGGAAGAAGGGGCCTGCAGGACCCATTGGGAATGAGTTTAATACTGAAGTCTGGAATG TAAGCTCATGCCCTAGAGGCCTCTCCATATGGCTGGTCAGGGGAGCTGCCTTCAGGCTTG TGCCCCGTGTGCTCAGCAGCTGCCTCTGTCCCCCTCTACTGTCCCTTTCACACCTTGCCT GGCCAAGGGGCTAGACCTCCCAGGCTAAGCCTCAGATTCAGTGCAGGACACAAGCTCATG CCCCCGTCTTGCCAGTGACACTTGAAGCCTCCCGACTTCCACAGAGTGCTTCAGGACACA TTTTGAGTGGTATTTTCTTTTCTTTTTTTCTTCTTTTTTTTTTTTTTGAGATGGAGTCTC GCTCTGTTGCCCAGGCTGGAGTGCAGTGGCCTGATCTCGGCTCACTGCAACCTCTGCCTC CCAGGTTCAAGCGATTCTTCTGCCTCAGCCTCCAGAGTAGCTGGGACTATAGACATGCAC CACCACGCCCGGCTAATTTTGTATTTTTGGTCGAGACGGGGTTTTGCCATGTTAGTCAGG CTGGTCTTGAACTCCTGACCTCAAGTGATCCACCACCTCGGCCTCCCAAAGTGTTGAGAT GACAGGCACGAGCCACCAGGCCCAGCCTGAGTGGTATTTTCTTTAGGGACCAGGTAGACT TTAAAACGAGGGTAAGAGAAAAGCCAGTGTCTTTCTGAGGTAAATAATTTCTGCCAGGAA ACTTCCCAGCCCCACCAGCAGCCCCCCTAAAAAAATCACTCGTGTCCCCAGGGACTTCTA AAGCTTGGGGCTCCAGGAAATCATCCAGTAGAGTTGGAGATTCAGAGATTTCTTGAAGCC AGGGACATGCTCCTAACTCCTTTCCCATTAAAGGTGTTAGAATAGACCAGAGGGTGTCCC TTTTCCACAGTAATGGGATCGGCTGGTGTGCCTTCAGGGAGGAAGAGGGAGGTGGTCAAG CTTGAAAAACTGGCTTTAGGATGGTTCTGACTTTGTTCTCCCTCCCCAAGTGTTCTCAAC CTCCATTCTGCAGTGTTCAGAGTTTTAGGGAAAGGGTTTGGGTGCCCCAGCATCCAGGTG TTGTGTGGCTTAGCGCATGTGAAGTGAAAACCTTCTGGGGTTGTTTGGAAGCAGCTTTCT GGTTCTTGTGATTGTATCCTGAGGTCCCAGAACCCTATTCTCCCACGAGGATCCTCAGTG ACCATGGTGGCCACACGCCTGGCCAGCCTGCTGGCTCCTGGGTGAGCTGAAGAACCTTGC CTGTGGCACTTTTCGAGGGTGAGCTGGAACCGAGAGAACATGGTCCCCGTGCTGGGACTC ATGCGGGTCATTTCCTGCCGGCCTGGTTTCGCCTGGTCGTGTCTTTATGAGCACCATGTA AGCCTCCTTGTATTGAGATAATTGGGCATTAAACATTAAACTGCAGCTCTGGGAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC >OriGene 5' read for BC007609 unedited
AGCGTACAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTAGAA TGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTTTGCCTC TTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTGGTCGCC TCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCTCCTGTG GAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCTCCCCTT GAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGCATGGGG GCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTGGTCCAG GAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAGGGTCAG ATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGCATCATT CTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCATTAAGGA CTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGGTGACTT GTTCACTCCTTTTTTCCCCAGTATACTGAANGGGTGACAGAGAGAGGTCTTCATGGCAGA CCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGGGGTCCC TGAGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAAGCTTGATCATCCCACATTGTCCCT TCAGCTCAGCTGCTCTTCTTCCCCACCCACCCTGGGATGGTGGTGCTCTGGGCCTGACCC AAGCTATGACTTCTG |
| Restriction Sites | Please inquire |
| ACCN | BC007609 |
| Insert Size | 2917 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC007609.1, AAH07609.1 |
| RefSeq Size | 2917 bp |
| Locus ID | 1870 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer |
| Gene Summary | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008] |
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