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P2RX4 (NM_002560) Human Untagged Clone
CAT＃: SC122124
P2RX4 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4)
CNY 3,656.00
| Cited in 2 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | P2X4; P2X4R |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC122124 sequence for NM_002560 edited (data generated by NextGen Sequencing)
ATGGCGGGCTGCTGCGCCGCGCTGGCGGCCTTCCTGTTCGAGTACGACACGCCGCGCATC GTGCTCATCCGCAGCCGCAAAGTGGGGCTCATGAACCGCGCCGTGCAACTGCTCATCCTG GCCTACGTCATCGGGTGGGTGTTTGTGTGGGAAAAGGGCTACCAGGAAACTGACTCCGTG GTCAGCTCCGTTACGACCAAGGTCAAGGGCGTGGCTGTGACCAACACTTCTAAACTTGGA TTCCGGATCTGGGATGTGGCGGATTATGTGATACCAGCTCAGGAGGAAAACTCCCTCTTC GTCATGACCAACGTGATCCTCACCATGAACCAGACACAGGGCCTGTGCCCCGAGATTCCA GATGCGACCACTGTGTGTAAATCAGATGCCAGCTGTACTGCCGGCTCTGCCGGCACCCAC AGCAACGGAGTCTCAACAGGCAGGTGCGTAGCTTTCAACGGGTCCGTCAAGACGTGTGAG GTGGCGGCCTGGTGCCCGGTGGAGGATGACACACACGTGCCACAACCTGCTTTTTTAAAG GCTGCAGAAAACTTCACTCTTTTGGTTAAGAACAACATCTGGTATCCCAAATTTAATTTC AGCAAGAGGAATATCCTTCCCAACATCACCACTACTTACCTCAAGTCGTGCATTTATGAT GCTAAAACAGATCCCTTCTGCCCCATATTCCGTCTTGGCAAAATAGTGGAGAACGCAGGA CACAGTTTCCAGGACATGGCCGTGGAGGGAGGCATCATGGGCATCCAGGTCAACTGGGAC TGCAACCTGGACAGAGCCGCCTCCCTCTGCTTGCCCAGGTACTCCTTCCGCCGCCTCGAT ACACGGGACGTTGAGCACAACGTATCTCCTGGCTACAATTTCAGGTTTGCCAAGTACTAC AGAGACCTGGCTGGCAACGAGCAGCGCACGCTCATCAAGGCCTATGGCATCCGTTTCGAC ATCATTGTGTTTGGGAAGGCAGGGAAATTTGACATCATCCCCACTATGATCAACATCGGC TCTGGCCTGGCACTGCTAGGCATGGCGACCGTGCTGTGTGACATCATAGTCCTCTACTGC ATGAAGAAAAGACTCTACTATCGGGAGAAGAAATATAAATATGTGGAAGATTACGAGCAG GGTCTTGCTAGTGAGCTGGACCAGTGA Clone variation with respect to NM_002560.2 465 t=>c;954 c=>t >OriGene 5' read for NM_002560 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCAGACCGACTAGG GGACTGGGAGCGGGCGGCGCGGTCATGGCGGGCTGCTGCGCCGCGCTGGCGGCCTTCCTG TTCGAGTACGACACGCCGCGCATCGTGCTCATCCGCAGCCGCAAAGTGGGGCTCATGAAC CGCGCCGTGCAACTGCTCATCCTGGCCTACGTCATCGGGTGGGTGTTTGTGTGGGAAAAG GGCTACCAGGAAACTGACTCCGTGGTCAGCTCCGTTACGACCAAGGTCAAGGGCGTGGCT GTGACCAACACTTCTAAACTTGGATTCCGGATCTGGGATGTGGCGGATTATGTGATACCA GCTCAGGAGGAAAACTCCCTCTTCGTCATGACCAACGTGATCCTCACCATGAACCAGACA CAGGGCCTGTGCCCCGAGATTCCAGATGCGACCACTGTGTGTAAATCAGATGCCAGCTGT ACTGCCGGCTCTGCCGGCACCCACAGCAACGGAGTCTCAACAGGCAGGTGCGTAGCTTTC AACGGGTCCGACAAGACGTGTGAGGTGGCGGCCTGGTGCCCTGTGGCAGATGACACACAC GTGCCACAACCTGCTTTTTTAAAGGCTGCAGAAAACTTCACTCTTTGTGGTTAACAACAA CATCTGGTATCCCAAATGTAATTTCAGGAAGAGGAGTATTCTTTCCAACATCCCCACTAC TGACCTAAAGTCGTGCATTTTTGATGCTAAAACACATCCCTTCTCGCCCATTATTCCGCC TGGCAACATAGTGGAAAACGCAGAACCAGTTTTCCAGACATGGCCGCGGAGGGAAGCCTT ATGGGCATCCACGCAACTTGGGACTGCAACCTGGACAAAGCCGTCTCCTTTTGGTTGCCA AG >OriGene 3' read for NM_002560 unedited
CCGCGGCCGCAATCNATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTAAAAAAAATCACGCTTTAATGTCTGGGCCTCGATCACCTTAGCCCAGC CCTTTTTTGAGGAAAAATGCCAACTCTTCCCCATGGCTTCAGGGAATGGGCGGGGGGAAA CCTGCACCCCAACCCTGCTACAAATTTAGTTTCTGGAACCAGGCGGCCTCCCCTGGGGGA TAAAATGCTTGAACAAACCCCCCCTGCCTAAAAGGACTGGGCCTGTCCTGGAAAAAGCTG GAAACCGGAGGCCTCTGAACAAAACCGGTTCCACCCCTGAAACCCCAATAGTGCCACCGT GCGTGGCCACCGCTCCCCCCAAACCCCCAGGGCGGGGGAAAACCTAAGTTCCCCCCATCA AGAACAGACTGCTTCTCTCTTGTGGCGAGTGGGCAACCCCTCCCTGCCACCACTCCAAAG CACCCTTGGGGCACCCTGTGTCCTCCCGCCTCGGCCCCCATCCCAATTCAAACAGCCTCT GCGAGAGTTGGGGCCCCTTCCCCCTTTCTCTCCCTCTTTTTCCTCCCCGGGCGCCTCCGT ATCCCCCTCCTCGGTCCCCCCCCCTTCCTCCCCCCCGCTCACCCCACATCTCCCATACTA CTCACCCAATTTCTCTCCTCCCCCCACTTCCACTCTTTCACCTCCCTCTCTCCACGCCCT CCCTTCCCAATCTCCCCCGCCACCCTTCCCTCCTCCCCTCCCCCCATTCCCTTTCCCCCT TTCGCCACCTCTATCCCCGTGTCCTTTTATCCATTCCCCCTTTTCACCCTACCTATTCCC ACTCCACACTATTTGTCTCTTTACACCTCCTGTTCACCCCCCCCTCCCTTTTCTTTTGTA AGCGTGTGACCCCCCCTGCCCTTTCCCCCTCTCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002560 |
| Insert Size | 1910 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002560.2, NP_002551.2 |
| RefSeq Size | 2043 bp |
| RefSeq ORF | 1167 bp |
| Locus ID | 5025 |
| UniProt ID | Q99571 |
| Domains | P2X_receptor |
| Protein Families | Druggable Genome, Ion Channels: ATP Receptors, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
| Gene Summary | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012] Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Sequence Note: Translation provided for the transcript variants two and three is predicted. The start codon is the same as in the predominant transcript variant (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Lidocaine Preferentially Inhibits the Function of Purinergic P2X7 Receptors Expressed in Xenopus Oocytes
,Okura, D;Horishita, T;Ueno, S;Yanagihara, N;Sudo, Y;Uezono, Y;Minami, T;Kawasaki, T;Sata, T;,
Anesth. Analg.
,PubMed ID 25695577
[P2RX4]
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Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse
,Tobias Woehrle, Linda Yip, Abdallah Elkhal, Yuka Sumi, Yu Chen, Yongli Yao, Paul A. Insel, and Wolfgang G. Junger,
Blood, Nov 2010; 116: 3475 - 3484
[P2RX4]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207613 | P2RX4 (Myc-DDK-tagged)-Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4) |
CNY 3,656.00 |
|
| RC207613L1 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC207613L2 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), mGFP tagged |
CNY 5,890.00 |
|
| RC207613L3 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC207613L4 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), mGFP tagged |
CNY 6,056.00 |
|
| RG207613 | P2RX4 (tGFP-tagged) - Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4) |
CNY 5,256.00 |
|
| SC324305 | P2RX4 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4) |
CNY 3,656.00 |
