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GRIK2 (NM_021956) Human Untagged Clone
CAT＃: SC121951
GRIK2 (untagged)-Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1
CNY 6,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_021956 edited
GGGCGGCCGCGAATTCGGCACGAGCCTCGTGCCGAATTCGGCACGAGGCTTTTCCGCCCG ACCTCCTCCGGCTGCTCCTCCCCGAGGACCACCCCACCCCCTCCCCGCCCACCTCACCCC TAGCTCCAGGCTCGCGCGGCCGGACATTGTGGGTGTGCGTGCTGGATTTCTCCCGGATGC TCTCCGACTAACATGGATGTCCCACCATTCCTTGCAGTGGAAGGTTGTTCCTTGGCGCAG TGAGTGAAGAACATGCAGCGATTGCTAATGGGTTTGGGAAGCGGAGACTCCTTCCTCTCT CTATGACCATGCCGTGATCGTGTCTGCGGTCACCACTCGACGCATCCTCATTTCTACCCG AACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCGTGCGTGTGGGCACAGAAACA CCATGAAGATTATTTTCCCGATTCTAAGTAATCCAGTCTTCAGGCGCACCGTTAAACTCC TGCTCTGTTTACTGTGGATTGGATATTCTCAAGGAACCACACATGTATTAAGATTTGGTG GTATTTTTGAATATGTGGAATCTGGCCCAATGGGAGCTGAGGAACTTGCATTCAGATTTG CTGTGAACACAATTAACAGAAACAGAACATTGCTACCCAATACTACCCTTACCTATGATA CCCAGAAGATAAACCTTTATGATAGTTTTGAAGCATCCAAGAAAGACCTTTATCTCCTCT TCAGCCTGTGATCAGCTGTCTCTTGGGGTGGCTGCCATCTTCGGGCCTTCACACAGCTCA TCAGCAAACGCAGTGCAGTCCATCTGCAATGCTCTGGGAGTTCCCCACATACAGACCCGC TGGAAGCACCAGGTGTCAGACAACAAAGATTCCTTCTATGTCAGTCTCTACCCAGACTTC TCTTCACTCAGCCGTGCCATTTTAGACCTGGTGCAGTTTTTCAAGTGGAAAACCGTCACG GTTGTGTATGATGACAGCACTGGTCTCATTCGTTTGCAAGAGCTCATCAAAGCTCCATCA AGGTATAATCTTCGACTCAAAATTCGTCAGTTACCTGCTGATACAAAGGATGCAAAACCC TTACTAAAAGAAATGAAAAGAGGCAAGGAGTTTCATGTAATCTTTGATTGTAGCCATGAA ATGGCAGCAGGCATTTTAAAACAGGCATTAGCTATGGGAATGATGACAGAATACTATCAT TATATCTTTACCACTCTGGACCTCTTTGCTCTTGATGTTGAGCCCTACCGATACAGTGGT GTTAACATGACAGGGTTCAGAATATTAAATACAGAAAATACCCAAGTCTCCTCCATCATT GAAAAGTGGTCGATGGAACGATTGCAGGCACCTCCGAAACCCGATTCAGGTTTGCTGGAT GGATTTATGACGACTGATGCTGCTCTAATGTATGATGCTGTGCATGTGGTGTCTGTGGCC GTTCAACAGTTTCCCCAGATGACAGTCAGTTCCTTGCAGTGTAATCGACATAAACCCTGG CGCTTCGGGACCCGCTTTATGAGTCTAATTAAAGAGGCACATTGGGAAGGCCTCACAGGC AGAATAACTTTCAACAAAACCAATGGCTTGAGAACAGATTTTGATTTGGATGTGATCAGT CTGAAGGAAGAAGGTCTAGAAAAGATTGGAACGTGGGATCCAGCCAGTGGCCTGAATATG ACAGAAAGTCAAAAGGGAAAGCCAGCGAACATCACAGATTCGTTATCCAATCGTTCTTTG ATTGTTACCACCATTTTGGAAGAGCCTTATGTCCTTTTTAAGAAGTCTGACAAACCTCTC TATGGTAATGATCGATTTGAAGGCTATTGCATTGATCTCCTCAGAGAGTTATCTACAATC CTTGGCTTTACATATGAAATTAGACTTGTGGAAGATGGGAAATATGGAGCCCAGGATGAT GCCAATGGACAATGGAATGGAATGGTTCGTGAACTAATTGATCATAAAGCTGACCTTGCA GTTGCTCCACTGGCTATTACCTATGTTCGAGAGAAGGTCATCGACTTTTCCAAGCCCTTT ATGACACTTGGAATAAGTATTTTGTACCGCAAGCCCAATGGTACAAACCCAGGCGTCTTC TCCTTCCTGAATCCTCTCTCCCCTGATATCTGGATGTATATTCTGCTGGCTTGCTTGGGT GTCAGTTGTGTGCTCTTTGTCATAGCCAGGTTTAGTCCTTATGAGTGGTATAATCCACAC CCTTGCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACCTTGCTAAATAGTTTCTGG TTTGGAGTTGGAGCTCTCATGCGGCAAGGTTCTGAGCTCATGCCCAAAGCACTGTCCACC AGGATAGTGGGAGGCATTTGGTGGTTTTTCACACTTATCATCATTTCTTCGTATACTGCT AACTTAGCCGCCTTTCTGACAGTGGAACGCATGGAATCCCCTATTGACTCTGCTGATGAT TTAGCTAAACAAACCAAGATAGAATATGGAGCAGTAGAGGATGGTGCAACCATGACTTTT TTCAAGAAATCAAAAATCTCCACGTATGACAAAATGTGGGCCTTTATGAGTAGCAGAAGG CAGTCAGTGCTGGTCAAAAGTAATGAAGAAGGAATCCAGCGAGTCCTCACCTCTGATTAT GCTTTCCTAATGGAGTCAACAACCATCGAGTTTGTTACCCAGCGGAACTGTAACCTGACA CAGATTGGCGGCCTTATAGACTCTAAAGGTTATGGCGTTGGCACTCCCATGGGTTCTCCA TATCGAGACAAAATTACCATAGCAATTCTTCAGCTGCAAGAGGAAGGCAAACTGCATATG ATGAAGGAGAAATGGTGGAGGGGCAATGGTTGCCCAGAAGAGGAGAGCAAAGAGGCCAGT GCCCTGGGGGTTCAGAATATTGGTGGCATCTTCATTGTTCTGGCAGCCGGCTTGGTGCTT TCAGTTTTTGTGGCAGTGGGAGAATTTTTATACAAATCCAAAAAAAACGCTCAATTGGAA AAGAGGTCCTTCTGTAGTGCCATGGTAGAAGAATTGAGGATGTCCCTGAAGTGCCAGCGT CGGTTAAAACATAAGCCACAGGCCCCAGTTATTGTGAAAACAGAAGAAGTTATCAACATG CACACATTTAACGACAGAAGGTTGCCAGGTAAAGAAACCATGGCATAAAGCTGGGAGGCC AAACACCCAAGCACAAACTGTCGTCTTTTTCCAAACAATTTAGCCAGAATGTTTCCTGTG GAAATATGCAACCTGTGCAAAATAAAATGAGTTACCTCATGCCGCTGTGTCTATGAACTA GAGACTCTGTGATCTAAGCAGTTGCAATGATCAGACTTGATTTACAAGCATCATGGATCA ACCAAGTTACACGGGGTTACACTGTTAATCATGGGTTCCTCCCTTCTTCTGAGTGAATGT TAACATGCGCATTTTGTGGCTGATTTCAAATGCAGTCCAGTGAGAAATTACAGGTTCCTT TTGAAGCTCAACTGTTGCCAGGAGATGGAATATCAATGCCCAACAGGGCAACCAA >OriGene 5' read for NM_021956 unedited
AGTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGCCTCGTGCC GAATTCGGCACGAGGCTTTTCCGCCCGACCTCCTCCGGCTGCTCCTCCCCGAGGACCACC CCACCCCCTCCCCGCCCACCTCACCCCTAGCTCCAGGCTCGCGCGGCCGGACATTGTGGG TGTGCGTGCTGGATTTCTCCCGGATGCTCTCCGACTAACATGGATGTCCCACCATTCCTT GCAGTGGAAGGTTGTTCCTTGGCGCAGTGAGTGAAGAACATGCAGCGATTGCTAATGGGT TTGGGAAGCGGAGACTCCTTCCTCTCTCTATGACCATGCCGTGATCGTGTCTGCGGTCAC CACTCGACGCATCCTCATTTCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTG GGTGCCGTGCGTGTGGGCACAGAAACACCATGAAGATTATTTTCCCGATTCTAAGTAATC CAGTCTTCAGGCGCACCGTTAAACTCCTGCTCTGTTTACTGTGGATTGGATATTCTCAAG GAACCACACATGTATTAAGATTTGGTGGTATTTTTGAATATGTGGAATCTGGCCCAATGN GAGCTGAGGAACTTGCATTCAGATTTGCTGTGAACACAATTAACAGAAACAGAACATTGC TACCCAATACTACCCTTACCTATGATACCCAGAAGATAAACCTTTATGATAGTTTTGAAG CATCCAAGAAAGCCTGTGATCAGCTGTCTCTTGGGGTGGCTGCCATCTTTCGGGCCTTCA CCAGCTCATCAGCAAACGCAGTGCAGTCCATCTGCAATGCTCTGGGAGTTTCCCACATAC AGACCCGCTGGAAACACCAGTGTTAGACAACAAAGATTCTCTCTATAGTAGGTTTTACCA GAACTTTTTTTCATCAGCCGGGCCATTTT >OriGene 3' read for NM_021956 unedited
TTAAAAGGGTTTACTACTTGNACCGCAGACCGCAATCNANGATCGATTTTTTTTCTTTTT TTTTATATTCTTAGTGACACTTTTATTGGTTGCCCTGTTGGGCATTGATATTCCATCTCC TGGCAACAGTTGAGCTTCAAAAGGAACCTGTAATTTCTCACTGGACTGCATTTGAAATCA GCCACAAAATGCGCATGTTAACATTCACTCAGAAGAAAGGAGGAACCCATGATTTTCAGT GTAACCCCGTGTAACTTGGTTGATCCATGATGCTTGTAAATCAAGTCTGATCATTGCAAC TGCTTAGATCACAGAGTCTCTAGTTCATAGACACAGCGGCATGAAGTAACTCATTTTATT TTGCACAGGGTGCATATTTCCACAGGAAACATTCTGGCTAAATTGTTTGGAAAAAGAGAC AGTTTGTGCTTGGGTGTTTGCCCTCCAGCTTATGCCTGGTTTCTTTACCTGGCAACCTTT GTCGTAAAGGTGGCCATGTGAAACTTCTTCTGGTTTCACAAAACTGGGCCCTGGGCTTAA GTTTAACCGACCCTGGACCTTAAGGAACTCTAATTTTTTACCATGGCCTCAAAAGGACCC TTTTTCATTGACCTTTTTTTTGGATTTGATAAAAATTCCCCCGGCCCCAAACTGAAACCC CAGCCGGGTGCAAAAAATGAAAGCCCCCATTTTTGAACCCCAGGGCCTGGCTTTTTGTTT CTTTTTGGAAACTTTGCCCCCCCTTTTTCTTTTAATAGGAGTGCTTCCTTTCCCCTAAAA AATCCGGGAATTTTGCCCTTTGGAACCCGGGGGGGCCCCTTTCCCTTTAGTTAAGGCCCA ATTGGGAGGGCAACCCCGGGGAAACCCTGGGGTGGGCCCTTTGAAAAATTCAGGGGGGAA CGGGACTCTTTTTTTTTTGAACCCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021956 |
| Insert Size | 3460 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021956.2, NP_068775.1 |
| RefSeq Size | 3322 bp |
| RefSeq ORF | 2727 bp |
| Locus ID | 2898 |
| UniProt ID | Q13002 |
| Domains | lig_chan, ANF_receptor |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longer isoform (1). RNA editing changes Ile567Val, Tyr571Cys and Gln621Arg. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222369 | GRIK2 (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1 |
CNY 6,648.00 |
|
| RC222369L1 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, Myc-DDK-tagged |
CNY 9,048.00 |
|
| RC222369L2 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RC222369L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC222369L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RG222369 | GRIK2 (tGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1 |
CNY 8,248.00 |
