HHIP (NM_022475) Human Untagged Clone
CAT#: SC120676
HHIP (untagged)-Human hedgehog interacting protein (HHIP)
CNY 5,648.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HIP |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI |
ACCN | NM_022475 |
Insert Size | 2103 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_022475.2 |
RefSeq Size | 3555 bp |
RefSeq ORF | 2103 bp |
Locus ID | 64399 |
UniProt ID | Q96QV1 |
Domains | EGF |
Protein Families | Secreted Protein |
Protein Pathways | Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer |
MW | 78.9 kDa |
Gene Summary | This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206868 | HHIP (Myc-DDK-tagged)-Human hedgehog interacting protein (HHIP) |
CNY 5,128.00 |
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RC206868L1 | Lenti ORF clone of Human hedgehog interacting protein (HHIP), Myc-DDK-tagged |
CNY 7,528.00 |
|
RC206868L2 | Lenti ORF clone of Human hedgehog interacting protein (HHIP), mGFP tagged |
CNY 7,700.00 |
|
RC206868L3 | Lenti ORF clone of Human hedgehog interacting protein (HHIP), Myc-DDK-tagged |
CNY 7,700.00 |
|
RC206868L4 | Lenti ORF clone of Human hedgehog interacting protein (HHIP), mGFP tagged |
CNY 7,700.00 |
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RG206868 | HHIP (tGFP-tagged) - Human hedgehog interacting protein (HHIP) |
CNY 6,728.00 |