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Frataxin (FXN) (NM_000144) Human Untagged Clone
CAT＃: SC120073
FXN (untagged)-Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CyaY; FA; FARR; FRDA; X25 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC120073 representing NM_000144.
Blue=Insert sequence Red=Cloning site Green=Tag(s) CGTGGCCTGCGCACCGACATCGATGCGACCTGCACGCCCCGCCGCGCAAGTTCGAACCAACGTGGCCTC AACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGC CACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAG TTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTC TTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATC TGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCAC GACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTG TCTTCCTTGGCCTATTCCGGAAAAGATGCTTGA >OriGene 5' read for NM_000144 unedited
GTCAGCATTTGTATACGACTCCTATAGGCGGCNCGCGATTCGGCACGAGCCGGACAGCAT GTGGACTCTCGGGCGCCGCGCAGTAGCCGGCCTCCTGGCGTCACCCAGCCCGGCCCAGGC CCAGACCCTCACCCGGGTCCCGCGGCCGGCAGAGTTGGCCCCACTCTGCGGCCGCCGTGG CCTGCGCACCGACATCGATGCGACCTGCACGCCCCGCCGCGCAAGTTCGAACCAACGTGG CCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATC TGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGA AACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGA GGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGG AACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAG TGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTC CCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTC TTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTANAA GCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTNGAGTCTGGTTTTTGGTGGTGGTG TTTATTTTTTTTATTCCTGCTNTTGAGGGACAGTGGGCTATGTGTCACAGCTCTGTAGAA GAATGTGTNGCCTNCTACCTGCCCCCAGTTCTGATTTTAAATTCTATGGAGATTTTTGGG ATGTCGATTTCTCCTNACATGAACCC >OriGene 3' read for NM_000144 unedited
CGTACACTTGGACGCGGCCCATCTANGATCGGTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTATTATTATTATTATTTTATTGGTATTATTATTTTGAGACAG AGATTTTGCTCAGTCACCCAGGTTACAGGGCAATGGCACGATCTCGGCCCACTGGAACCT CCACCTCTGGGGTCAAGCGATTCTTCCGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGC CCCTGCCCTCATACCCGGGTAATTTTTTGGATTTTTAGTAAAGACGGGGTTTCATCATGT TGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGGGATCCACCCACCTTGGCCTCCAAAAG TGCTGGGATTACCGGGGTGAGCCACCGCGCCAGGCCAAGGATGGCTATTATTTTCACCTG AATTCCACTGAAATCACGATTGGGCAACACCCATAACAATGTTTCCTATATAGCTTAAAA ACTGGTCTTTGTCATCCCCTCATCTACCCCATAGGGAATTAGAACTAGCCTGGTAGGTTG CTTGACCGGACCACTGAATGCTGGGAATCAACCATACCCTATTCTCTCATTTAACAGATG GGGAAACCGAGGTCCAGGGAATTTGGGAAACTTGTCCACCAAGGGACAACTACTTTGGGG CTGAACTATGTCTAGGACCAGGGGTCTCTTTATCAACATGAGTATCTCCCTCCTTTATCG GCCCCTTTCTGTTTACAAGGCACCTCCCCACTCCCTGGATTTTGTTTGTGCCCCTCCCTC CCTCCCCTCATGAGAACGGCCTTTTTTCCCCCTTTCCTTGGCCTGGGGAGAATTTTTGGC CTCCTGGGGGCCACCGGTTCCCAACCAACCCTTTAAAATGGGAAAAATT |
| Restriction Sites | Please inquire |
| ACCN | NM_000144 |
| Insert Size | 633 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000144.3 |
| RefSeq Size | 2262 bp |
| RefSeq ORF | 633 bp |
| Locus ID | 2395 |
| UniProt ID | Q16595 |
| Domains | Frataxin_Cyay |
| Protein Families | Druggable Genome |
| MW | 23.1 kDa |
| Gene Summary | This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Drp1-dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia
,Johnson, J;Mercado-Ayón, E;Clark, E;Lynch, D;Lin, H;,
Pharmacology research & perspectives
,PubMed ID 33951329
[FXN]
|
|
Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique
,Sanchez, N;Chapdelaine, P;Rousseau, J;Raymond, F;Corbeil, J;Tremblay, JP;,
Mitochondrion
,PubMed ID 27350085
[FXN]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204880 | FXN (Myc-DDK-tagged)-Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 2,400.00 |
|
| RC204880L1 | Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204880L2 | Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC204880L3 | Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204880L4 | Lenti ORF clone of Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG204880 | FXN (tGFP-tagged) - Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 4,000.00 |
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