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UMPS (NM_000373) Human Untagged Clone
CAT＃: SC119938
UMPS (untagged)-Human uridine monophosphate synthetase (UMPS), transcript variant 1
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OPRT |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119938 sequence for NM_000373 edited (data generated by NextGen Sequencing)
ATGGCGGTCGCTCGTGCAGCTTTGGGGCCATTGGTGACGGGTCTGTACGACGTGCAGGCT TTCAAGTTTGGGGACTTCGTGCTGAAGAGCGGGCTTTCCTCCCCCATCTACATCGATCTG CGGGGCATCGTGTCTCGACCGCGTCTTCTGAGTCAGGTTGCAGATATTTTATTCCAAACT GCCCAAAATGCAGGCATCAGTTTTGACACCGTGTGTGGAGTGCCTTATACAGCTTTGCCA TTGGCTACAGTTATCTGTTCAACCAATCAAATTCCAATGCTTATTAGAAGGAAAGAAACA AAGGATTATGGAACTAAGCGTCTTGTAGAAGGAACTATTAATCCAGGAGAAACCTGTTTA ATCATTGAAGATGTTGTCACCAGTGGATCTAGTGTTTTGGAAACTGTTGAGGTTCTTCAG AAGGAGGGCTTGAAGGTCACTGATGCCATAGTGCTGTTGGACAGAGAGCAGGGAGGCAAG GACAAGTTGCAGGCGCACGGGATCCGCCTCCACTCAGTGTGTACATTGTCCAAAATGCTG GAGATTCTCGAGCAGCAGAAAAAAGTTGATGCTGAGACAGTTGGGAGAGTGAAGAGGTTT ATTCAGGAGAATGTCTTTGTGGCAGCGAATCATAATGGTTCTCCCCTTTCTATAAAGGAA GCACCCAAAGAACTCAGCTTCGGTGCACGTGCAGAGCTGCCCAGGATCCACCCAGTTGCA TCGAAGCTTCTCAGGCTTATGCAAAAGAAGGAGACCAATCTGTGTCTATCTGCTGATGTT TCACTGGCCAGAGAGCTGTTGCAGCTAGCAGATGCTTTAGGACCTAGTATCTGCATGCTG AAGACTCATGTAGATATTTTGAATGATTTTACTCTGGATGTGATGAAGGAGTTGATAACT CTGGCAAAATGCCATGAGTTCTTGATATTTGAAGACCGGAAGTTTGCAGATATAGGAAAC ACAGTGAAAAAGCAGTATGAAGGAGGTATCTTTAAAATAGCTTCCTGGGCAGATCTAGTA AATGCTCACGTGGTGCCAGGCTCAGGAGTTGTGAAAGGCCTGCAAGAAGTGGGCCTGCCT TTGCATCGGGGGTGCCTCCTTATTGCGGAAATGAGCTCCACCGGCTCCCTGGCCACTGGG GACTACACTAGAGCAGCGGTTAGAATGGCTGAGGAGCACTCTGAATTTGTTGTTGGTTTT ATTTCTGGCTCCCGAGTAAGCATGAAACCAGAATTTCTTCACTTGACTCCAGGAGTTCAG TTGGAAGCAGGAGGAGATAATCTTGGCCAACAGTACAATAGCCCACAAGAAGTTATTGGC AAACGAGGTTCCGATATCATCATTGTAGGTCGTGGCATAATCTCAGCAGCTGATCGTCTG GAAGCAGCAGAGATGTACAGAAAAGCTGCTTGGGAAGCGTATTTGAGTAGACTTGGTGTT TGA Clone variation with respect to NM_000373.3 >OriGene 5' read for NM_000373 unedited
GTCAGAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGCCTCGTGCCGA ATTCGGCACGAGGAGGCAGCGCGCGACAATGGCGGTCGCTCGTGCAGCTTTGGGGCCATT GGTGACGGGTCTGTACGACGTGCAGGCTTTCAAGTTTGGGGACTTCGTGCTGAAGAGCGG GCTTTCCTCCCCCATCTACATCGATCTGCGGGGCATCGTGTCTCGACCGCGTCTTCTGAG TCAGGTTGCAGATATTTTATTCCAAACTGCCCAAAATGCAGGCATCAGTTTTGACACCGT GTGTGGAGTGCCTTATACAGCTTTGCCATTGGCTACAGTTATCTGTTCAACCAATCAAAT TCCAATGCTTATTAGAAGGAAAGAAACAAAGGATTATGGAACTAAGCGTCTTGTAGAAGG AACTATTAATCCAGGAGAAACCTGTTTAATCATTGAAGATGTTGTCACCAGTGGATCTAG TGTTTTGGAAACTGTTGAGGTTCTTCAGAAGCTGGGCTTGAAGGTCACTGATGCCATAGT GCTGTTGGACAGAGAGCAGGGAGGCAAGGACAAGTTGCAGGCGCACGGGATCCGCCTCCA CTCAGTGTGTACATTGTCCAAAATGCTGGAGATTCTCGAGCAGCAGAAAAAAGTTGATGC TGAGACAGTTGGGAGAGTGAAGAGGTTTATTCAGGAGAATGTCTTTGTGCCAGCGAATCA TAATGGTTCTCCCCTTTCTATAAAGGAAGCACCCCAAAGAACTCAGCTTTCGTTGCACGT GCCAAAGCTGCCCAGGGATCCACCCCAGTTGCATCGAAAGCTTCTCAAGCTTATGCAAAA GGAAGGAGACCAATCTGGGNCTATCTGCTGATGTTTCACTGGCCAGAGNACTGNTGCAGC TAACAGATGCTTTAGACA >OriGene 3' read for NM_000373 unedited
GGACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGCAAGCTTAAAAAT GAACTTATTATAGTATCAATGCGGTGATTACAAATTACTCAATATTTCCTAAAGACCATG AGAACTCCAGAACCCATTCTTACACAGGCCCTGTGGAAGAATCCAAGCAGGAATAATTGG ATTATTTCCAGCCAGTGACTTTCAGGGGACCACATATCTTCAATGTCTTCACATTGTATC TGAAAAATGTATCTGAAGCACTCAAACACCAAGTCTACTCAAATACGCTTCCCAAGCAGC TTTTCTGTACATCTCTGCTGCTTCCAGACGATCAGCTGCTGAGATTATGCCACGACCTAC AATGATGATATCGGAACCTCGTTTGCCAATAACTTCTTGTGGGCTATTGTACTGTTGGCC AAGATTATCTCCTCCTGCTTCCAACTGAACTCCTGGAGTCAAGTGAAGAAATTCTGGTTT CATGCTTACTCGGGAGCCAGAAATAAAACCAACAACAAATTCAGAGTGCTCCTCAGCCAT TCTAACCGCTGCTCTAGTGTAGTCCCCAGTGGCCAGGGAGCCGGTGGAGCTCATTTCCGC AATAAGGAGGCACCCCCGATGCAAAGGCAGGCCCACTTCTTGCAGGCCTTTCACAACTCC TGAGCCTGGCACCACGTGAGCATTTACTAGATCTGCCCAGGAAGCTATTTTAAAGATACC TCCTAAGAAGAAGGGGGAAAAAAGATATTTGCTGATTTTCAACAAAACCTCTAACCCCTC TGTCCACCAACCAACTANCATATGAAATNAATCTCCAGTNACATGTTAATGGAGAGATCA AAACTCTTCAGGAACTTNTAGTGATATCAGCAGACCCATGGTTCCATCTGTGAAACTGTA TCTGTTATTCAGGTAAGTANCTGGGTGAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000373 |
| Insert Size | 3630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000373.1, NP_000364.1 |
| RefSeq Size | 2244 bp |
| RefSeq ORF | 1443 bp |
| Locus ID | 7372 |
| UniProt ID | P11172 |
| Domains | Pribosyltran, OMPdecase |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism |
| Gene Summary | This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201324 | UMPS (Myc-DDK-tagged)-Human uridine monophosphate synthetase (UMPS), transcript variant 1 |
CNY 3,656.00 |
|
| RC201324L1 | Lenti ORF clone of Human uridine monophosphate synthetase (UMPS), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201324L2 | Lenti ORF clone of Human uridine monophosphate synthetase (UMPS), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201324L3 | Lenti ORF clone of Human uridine monophosphate synthetase (UMPS), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201324L4 | Lenti ORF clone of Human uridine monophosphate synthetase (UMPS), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG201324 | UMPS (tGFP-tagged) - Human uridine monophosphate synthetase (UMPS), transcript variant 1 |
CNY 5,256.00 |
