Cathepsin K (CTSK) (NM_000396) Human Untagged Clone
CAT#: SC119901
CTSK (untagged)-Human cathepsin K (CTSK)
CNY 2,400.00
CNY 2,950.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119901 sequence for NM_000396 edited (data generated by NextGen Sequencing)
ATGTGGGGGCTCAAGGTTCTGCTGCTACCTGTGGTGAGCTTTGCTCTGTACCCTGAGGAG ATACTGGACACCCACTGGGAGCTATGGAAGAAGACCCACAGGAAGCAATATAACAACAAG GTGGATGAAATCTCTCGGCGTTTAATTTGGGAAAAAAACCTGAAGTATATTTCCATCCAT AACCTTGAGGCTTCTCTTGGTGTCCATACATATGAACTGGCTATGAACCACCTGGGGGAC ATGACCAGTGAAGAGGTGGTTCAGAAGATGACTGGACTCAAAGTACCCCTGTCTCATTCC CGCAGTAATGACACCCTTTATATCCCAGAATGGGAAGGTAGAGCCCCAGACTCTGTCGAC TATCGAAAGAAAGGATATGTTACTCCTGTCAAAAATCAGGGTCAGTGTGGTTCCTGTTGG GCTTTTAGCTCTGTGGGTGCCCTGGAGGGCCAACTCAAGAAGAAAACTGGCAAACTCTTA AATCTGAGTCCCCAGAACCTAGTGGATTGTGTGTCTGAGAATGATGGCTGTGGAGGGGGC TACATGACCAATGCCTTCCAATATGTGCAGAAGAACCGGGGTATTGACTCTGAAGATGCC TACCCATATGTGGGACAGGAAGAGAGTTGTATGTACAACCCAACAGGCAAGGCAGCTAAA TGCAGAGGGTACAGAGAGATCCCCGAGGGGAATGAGAAAGCCCTGAAGAGGGCAGTGGCC CGAGTGGGACCTGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTTTTACAGC AAAGGTGTGTATTATGATGAAAGCTGCAATAGCGATAATCTGAACCATGCGGTTTTGGCA GTGGGATATGGAATCCAGAAGGGAAACAAGCACTGGATAATTAAAAACAGCTGGGGAGAA AACTGGGGAAACAAAGGATATATCCTCATGGCTCGAAATAAGAACAACGCCTGTGGCATT GCCAACCTGGCCAGCTTCCCCAAGATGTGA Clone variation with respect to NM_000396.3 >OriGene 5' read for NM_000396 unedited
GGTTCGACGATATTTGAACACGATCTCACTATAGGGCGGCCGCGAATTCGCACGAGGGAA ACGAAGCCAGACAACAGATTTCCATCAGCAGGATGTGGGGGCTCAAGGTTCTGCTGCTAC CTGTGGTGAGCTTTGCTCTGTACCCTGAGGAGATACTGGACACCCACTGGGAGCTATGGA AGAAGACCCACAGGAAGCAATATAACAACAAGGTGGATGAAATCTCTCGGCGTTTAATTT GGGAAAAAAACCTGAAGTATATTTCCATCCATAACCTTGAGGCTTCTCTTGGTGTCCATA CATATGAACTGGCTATGAACCACCTGGGGGACATGACCAGTGAAGAGGTGGTTCAGAAGA TGACTGGACTCAAAGTACCCCTGTCTCATTCCCGCAGTAATGACACCCTTTATATCCCAG AATGGGAAGGTAGAGCCCCAGACTCTGTCGACTATCGAAAGAAAGGATATGTTACTCCTG TCAAAAATCAGGGTCAGTGTGGTTCCTGTTGGGCTTTTAGCTCTGTGGGTGCCCTGGAGG GCCAACTCAAGAAGAAAACTGGCAAACTCTTAAATCTGAGTCCCCAGAACCTAGTGGATT GTGTGTCTGAGAATGATGGCTGTGGAGGGGGCTACATGACCAATGCCTTCCAATATGTGC AGAAGAACCGGGGTATTGACTCTGAAGATGCCTACCCATATGTGGGACAGGAAGAGAGTT GTATGTACAACCCAACAGGCAAGGCAGCTAAATGCANGAGGTACAGAGAGATCCCCCGAG GGAAATGAGAAGCCCTGAAGAAGGCAGTGGCCCCGAGTGGGACCTGTCTCTGTGGCCATT TGATGCAGCCTGCACTCCTTTCAGTTTACAGCAAAAGTGTGTATTATGATGAAAGCTGCC ATAGCGATAATCTGAACCCATGCGG >OriGene 3' read for NM_000396 unedited
ACAGGGAGCAAAATACTTTATTTCAAAAGTGCAAAGAAGGGGAAGACAAATCACATTTCT TTTTATCATGTAAACTTGTACCAAAGACTTATGAATAGATTTATGAATTGGAGTAGAAAA CATAGACATTTCTACCTTGAGGATATAGAAGGGAACTTAGGAAGTGAGAAGTCAGATTAC CCTAGTCCTCTAGGGTGCTTAAAGCTAACTAGTCCCGTGAATGAGAATCTAACCTATGTG AAAATCTCCAGCCTGTACCTGTACAGCATCAGCCCTGGGACAACACAGTCAGGGGCAGGC TGTAGTCACATCTCTTAGCCTAAGAGTACACAGCTGTCAGGGAAAGTCCTGATGGCCACA GTGAAAAAGGTCATGGGTGGAGAGAAGCAAAGTAGGAAGGATCATTTGAAGCACAAACAA ATGGGGAAACTGAACAGACAATCTCAGTATCACCACATCTGCTTCAAAAATAGCACACCA ACTCCCTTCCAAAGTGCATCGTTACACTGCACCATCGTGGAAGATATGGAAGAGCANGAT GGATTTGGCTGGCTGGAGTCACATCTTGGGGAAGCTGGCCAGGTTGGCATGCCACAGGCG TTGTCCTATTTCGAGCCATGAGAATATCCTTTGTTTCCCAGTTTTCTCCCAGCTGTTTTT ATTATCCAGTGCTTGTTCCCTTCTGATTCCTATCCCACTGCAAACCGCAGGTTCAGATAT CGTTATGCAGCTTTATCATATACACCACTTGCTGAAAACTGGAAGAGGCAGGCTGGATCA ATGGCCCAAACCCGGTCCCACTGGGCCCTGCCCTTTTAGGGCCTTTTAATTCCCCTGGGG ACCTTTTTGACCCCTTCCTTTAATTGGCTCGCCTGGNGGGGTGACAAACACCTTTTTCCT GGCCAACTGTGGGAGGCATTTATGATACAACACCCCGCTCTTTGCACATTGTGAAGGATG GTCCTTGGCCCCCTCCCAGATTTTTCTCAACACATATCCACAGTTTGGGGATCCAATAAG AAGTCACATCTTCCTG |
Restriction Sites | NotI-NotI |
ACCN | NM_000396 |
Insert Size | 1730 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000396.2, NP_000387.1 |
RefSeq Size | 1702 bp |
RefSeq ORF | 990 bp |
Locus ID | 1513 |
UniProt ID | P43235 |
Domains | Pept_C1 |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Lysosome |
Gene Summary | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204892 | CTSK (Myc-DDK-tagged)-Human cathepsin K (CTSK) |
CNY 3,600.00 |
|
RC204892L1 | Lenti ORF clone of Human cathepsin K (CTSK), Myc-DDK-tagged |
CNY 6,000.00 |
|
RC204892L2 | Lenti ORF clone of Human cathepsin K (CTSK), mGFP tagged |
CNY 5,890.00 |
|
RC204892L3 | Lenti ORF clone of Human cathepsin K (CTSK), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204892L4 | Lenti ORF clone of Human cathepsin K (CTSK), mGFP tagged |
CNY 6,000.00 |
|
RG204892 | CTSK (tGFP-tagged) - Human cathepsin K (CTSK) |
CNY 5,200.00 |
|
SC319622 | CTSK (untagged)-Human cathepsin K (CTSK) |
CNY 2,400.00 |
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