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IFNGR1 (NM_000416) Human Untagged Clone
CAT＃: SC119876
IFNGR1 (untagged)-Human interferon gamma receptor 1 (IFNGR1)
CNY 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD119; IFNGR; IMD27A; IMD27B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119876 sequence for NM_000416 edited (data generated by NextGen Sequencing)
ATGGCTCTCCTCTTTCTCCTACCCCTTGTCATGCAGGGTGTGAGCAGGGCTGAGATGGGC ACCGCGGATCTGGGGCCGTCCTCAGTGCCTACACCAACTAATGTTACAATTGAATCCTAT AACATGAACCCTATCGTATATTGGGAGTACCAGATCATGCCACAGGTCCCTGTTTTTACC GTAGAGGTAAAGAACTATGGTGTTAAGAATTCAGAATGGATTGATGCCTGCATCAATATT TCTCATCATTATTGTAATATTTCTGATCATGTTGGTGATCCATCAAATTCTCTTTGGGTC AGAGTTAAAGCCAGGGTTGGACAAAAAGAATCTGCCTATGCAAAGTCAGAAGAATTTGCT GTATGCCGAGATGGAAAAATTGGACCACCTAAACTGGATATCAGAAAGGAGGAGAAGCAA ATCATGATTGACATATTTCACCCTTCAGTTTTTGTAAATGGAGACGAGCAGGAAGTCGAT TATGATCCCGAAACTACCTGTTACATTAGGGTGTACAATGTGTATGTGAGAATGAACGGA AGTGAGATCCAGTATAAAATACTCACGCAGAAGGAAGATGATTGTGACGAGATTCAGTGC CAGTTAGCGATTCCAGTATCCTCACTGAATTCTCAGTACTGTGTTTCAGCAGAAGGAGTC TTACATGTGTGGGGTGTTACAACTGAAAAGTCAAAAGAAGTTTGTATTACCATTTTCAAT AGCAGTATAAAAGGTTCTCTTTGGATTCCAGTTGTTGCTGCTTTACTACTCTTTCTAGTG CTTAGCCTGGTATTCATCTGTTTTTATATTAAGAAAATTAATCCATTGAAGGAAAAAAGC ATAATATTACCCAAGTCCTTGATCTCTGTGGTAAGAAGTGCTACTTTAGAGACAAAACCT GAATCAAAATATGTATCACTCATCACGTCATACCAGCCATTTTCCTTAGAAAAGGAGGTG GTCTGTGAAGAGCCGTTGTCTCCAGCAACAGTTCCAGGCATGCATACCGAAGACAATCCA GGAAAAGTGGAACATACAGAAGAACTTTCTAGTATAACAGAAGTGGTGACTACTGAAGAA AATATTCCTGACGTGGTCCCGGGCAGCCATCTGACTCCAATAGAGAGAGAGAGTTCTTCA CCTTTAAGTAGTAACCAGTCTGAACCTGGCAGCATCGCTTTAAACTCGTATCACTCCAGA AATTGTTCTGAGAGTGATCACTCCAGAAATGGTTTTGATACTGATTCCAGCTGTCTGGAA TCACATAGCTCCTTATCTGACTCAGAATTTCCCCCAAATAATAAAGGTGAAATAAAAACA GAAGGACAAGAGCTCATAACCGTAATAAAAGCCCCCACCTCCTTTGGTTATGATAAACCA CATGTGCTAGTGGATCTACTTGTGGATGATAGCGGTAAAGAGTCCTTGATTGGTTATAGA CCAACAGAAGATTCCAAAGAATTTTCATGA Clone variation with respect to NM_000416.2 >OriGene 5' read for NM_000416 unedited
TCAAAATTTGTATACCATCATATAGGGCGGCCGCGAATTCGCACGAGGCCTCGTGCCGAA TTCGGCACGAGGCCAGCGACCGTCGGTAGCAGCATGGCTCTCCTCTTTCTCCTACCCCTT GTCATGCAGGGTGTGAGCAGGGCTGAGATGGGCACCGCGGATCTGGGGCCGTCCTCAGTG CCTACACCAACTAATGTTACAATTGAATCCTATAACATGAACCCTATCGTATATTGGGAG TACCAGATCATGCCACAGGTCCCTGTTTTTACCGTAGAGGTAAAGAACTATGGTGTTAAG AATTCAGAATGGATTGATGCCTGCATCAATATTTCTCATCATTATTGTAATATTTCTGAT CATGTTGGTGATCCATCAAATTCTCTTTGGGTCAGAGTTAAAGCCAGGGTTGGACAAAAA GAATCTGCCTATGCAAAGTCAGAAGAATTTGCTGTATGCCGAGATGGAAAAATTGGACCA CCTAAACTGGATATCAGAAAGGAGGAGAAGCANATCATGATTGACATATTTCACCCTTCA GTTTTTGTAAATGGAGACGAGCAGGAAGTCGATTATGATCCCGAAACTACCTGTTACATT ANGGTGTACAATGTGTATGTGAGAATGAACGGAAGTGAGATCCAGTANTAAATACTCACG CAGAAGGAAGATGATTGTGACGAGATTCAGTGCCAGTTAGCGATTCCAGTATCCTCACTG AATTCTCAGTACTGTNNGTTCAGCAGAAGAGTCCTACATGTGTGGGGGTGGTACCCACTG AAAGTCAAAAGAGTTTGTTTAACATTTTTCATAGCAGTATAAAAGGTCTCCTTGGATCCC AGTGTTGCTGCCTTACCACTCTTCCTAGGGCTTAACCTGGATTCCATCTGTTTATTTTAA GGAAAATTNATCCTTTGNAGGAAAAAGCCTATTTTTCCCCAG >OriGene 3' read for NM_000416 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGTTTTAAAATTCTTTATTTA AAAATCTCTAACTGTAATGTTTCATAAAAAATATACACGTTTCTATTTACATATTCCATT AATTCTATTAGTTTGAATTAGATTTTAAGTCCAATTTTGAAAAGCTTGCAGAATTTCTTC TGAAATTACTTAAAATTACTGTATGCATAAACTTACAAAAACATATGCTATACCAAGGCA GAGAAAAGAAAAAAAGTGAAGTGGCTACAAAGGTCCCTGGGGCATCACCTGCTCACCTAG GAACCAGGAGTACTGGATACTGTTCCGTTACTGGTAACCTATCTGGATGTAAAGGTTCAT AAGTTACAATGCTTTTTTTGTTTAAAAAAAAAAAAAAGTCTGTACTTTACAAGCCAAAAG TGAAAATGCCACACATCCTCTTTACGCTTTCATGTACACTAAGTCACTCCATTTGGTTGA TACCAACTAAGATACAATTTCTGAGATCATAATCTTTTCATGAAATTAAAGCAGAAAACT GTCCAGGAAAATCAGACTTCAAAGTTGGTGCAACTTAGCTGATCTCATGAAAATTCTTTG GAATCTTCTGTTGGTCTATAACCAATCAAGGACTCTTTACCGCTATCATCCACAAGTAGA TCCACTAGCACATGTGGTTTATCATAACCAAAGGAGGTGGGGGGCTTTTATTACGGTTAT GAGCTCTTGTCCTTTCTGTTTTATTTCACCTTTTTATTTGGGGGAAATTCTGAGTCAGAT AAGAGCTATGTGATTCAGACAGCTGGATCAGTATCAAACCATTTCTGAGTGATCACTCTA NACCATTCTGGAGGATACCAGTTTAAGCGAGCTCCAGGTCAAATGGTACACTTAAGGGAA AACTTCTTTTTTTTGAGTCAAAGCTGCCCGGACCCTCAGAATATTCTTAAAATACCACTT GGTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000416 |
| Insert Size | 2140 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000416.1, NP_000407.1 |
| RefSeq Size | 2059 bp |
| RefSeq ORF | 1470 bp |
| Locus ID | 3459 |
| UniProt ID | P15260 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity |
| Gene Summary | This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Human osteoarthritic chondrocytes are impaired in matrix metalloproteinase-13 inhibition by IFN-gamma due to reduced IFN-gamma receptor levels.
,null,
Osteoarthritis and cartilage
,PubMed ID 19285161
[IFNGR1]
|
|
Human osteoarthritic chondrocytes are impaired in matrix metalloproteinase-13 inhibition by IFN-? due to reduced IFN-? receptor levels
,R. Ahmada, M. El Mabrouka, J. Sylvestera and M. Zafarullah,
Osteoarthritis and Cartilage Volume 17, Issue 8, August 2009, Pages 1049-1055
[IFNGR1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202761 | IFNGR1 (Myc-DDK-tagged)-Human interferon gamma receptor 1 (IFNGR1) |
CNY 3,656.00 |
|
| RC202761L1 | Lenti ORF clone of Human interferon gamma receptor 1 (IFNGR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202761L2 | Lenti ORF clone of Human interferon gamma receptor 1 (IFNGR1), mGFP tagged |
CNY 5,890.00 |
|
| RC202761L3 | Lenti ORF clone of Human interferon gamma receptor 1 (IFNGR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202761L4 | Lenti ORF clone of Human interferon gamma receptor 1 (IFNGR1), mGFP tagged |
CNY 6,056.00 |
|
| RG202761 | IFNGR1 (tGFP-tagged) - Human interferon gamma receptor 1 (IFNGR1) |
CNY 5,256.00 |
|
| SC321055 | IFNGR1 (untagged)-Human interferon gamma receptor 1 (IFNGR1) |
CNY 3,656.00 |
