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EPX (NM_000502) Human Untagged Clone
CAT＃: SC119861
EPX (untagged)-Human eosinophil peroxidase (EPX)
CN¥ 5,248.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPO; EPP; EPX-PEN; EPXD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119861 sequence for NM_000502 edited (data generated by NextGen Sequencing)
ATGCATCTGCTCCCAGCCCTGGCAGGGGTCCTGGCCACACTCGTCCTCGCCCAGCCCTGT GAGGGCACTGACCCAGCCTCCCCTGGGGCAGTGGAGACCTCGGTCCTGCGAGACTGCATG GCAGAGGCCAAGTTGCTGGTGGATGCTGCCTACAATTGGACCCAGAAGAGCATCAAGCAG CGGCTTCGCAGCGGTTCAGCCAGCCCCATGGACCTCCTGTCCTACTTCAAACAACCGGTA GCAGCCACCAGGACAGTTGTTCGGGCCGCAGATTATATGCATGTGGCTTTGGGGCTGCTT GAAGAGAAGTTACAACCCCAGCGGTCCGGACCCTTCAATGTCACTGATGTGCTAACAGAA CCACACCTGCGGCTGCTGTCCCAGGCCAGTGGCTGTGCTCTCCGGGACCAGGCCGAGCGC TGCAGCGACAAGTACCGCACCATCACTGGACGGTGCAACAACAAGAGGAGACCCTTGCTA GGGGCCTCCAACCAGGCTCTGGCTCGCTGGCTGCCCGCCGAGTATGAGGATGGGCTGTCG CTCCCCTTCGGCTGGACCCCCAGCAGGAGGCGCAATGGCTTCCTTCTCCCTCTTGTCCGG GCTGTCTCCAACCAGATTGTGCGCTTCCCCAATGAGAGACTGACCTCCGACCGTGGCCGG GCCCTCATGTTCATGCAGTGGGGCCAGTTCATTGACCATGACCTGGACTTCTCCCCGGAG TCCCCGGCCAGAGTGGCCTTCACTGCAGGCGTTGACTGTGAGAGGACCTGCGCCCAGCTG CCCCCCTGCTTTCCCATCAAGATCCCACCCAATGACCCCCGCATCAAGAACCAGCGTGAC TGCATCCCTTTCTTCCGCTCGGCACCCTCATGCCCCCAAAACAAGAACAGAGTCCGCAAC CAGATCAACGCGCTCACCTCCTTTGTGGACGCCAGCATGGTGTATGGCAGTGAGGTCTCC CTCTCGCTGCGGCTCCGCAACCGGACCAACTACCTGGGGCTGCTGGCCATCAACCAGCGC TTTCAAGACAACGGCCGGGCCCTGCTGCCCTTCGACAACCTGCACGATGACCCCTGTCTC CTCACCAACCGCTCGGCGCGCATCCCCTGCTTCCTGGCAGGTGACACCCGATCAACGGAA ACCCCCAAACTGGCAGCCATGCACACCCTCTTTATGCGAGAGCACAACCGGCTGGCCACC GAGCTGAGACGCCTGAATCCCCGGTGGAATGGAGACAAACTGTACAATGAGGCTCGGAAG ATCATGGGGGCCATGGTCCAGATCATCACCTACCGAGACTTTCTGCCCCTGGTTCTGGGC AAGGCCCGGGCCAGGAGAACCCTGGGGCACTACAGGGGGTACTGCTCCAATGTGGACCCA CGGGTGGCCAATGTCTTCACCCTGGCCTTCCGCTTTGGCCACACAATGCTCCAGCCCTTC ATGTTCCGCTTGGACAGTCAGTACCGGGCCTCCGCACCCAACTCGCATGTCCCACTTAGC TCTGCCTTCTTTGCCAGCTGGCGGATCGTGTATGAAGGGGGCATCGACCCCATCCTCCGG GGCCTCATGGCCACCCCTGCCAAGCTGAACCGTCAGGATGCCATGTTAGTGGATGAGCTC CGGGACCGGCTGTTTCGGCAAGTGAGGAGGATTGGGCTGGACCTGGCAGCTCTCAACATG CAACGAAGCCGGGACCACGGCCTTCCAGGGTACAATGCTTGGAGGCGCTTCTGTGGGCTC TCCCAGCCCCGGAATTTGGCACAGCTTAGCCGGGTGCTGAAAAACCAGGACTTGGCAAGG AAGTTCCTGAATTTGTATGGAACACCTGACAACATTGACATCTGGATTGGGGCCATCGCT GAGCCTCTTTTGCCGGGGGCTCGAGTGGGGCCTCTTCTGGCTTGTCTGTTCGAGAACCAG TTCAGAAGAGCCCGAGACGGAGACAGGTTCTGGTGGCAGAAACGAGGTGTTTTCACCAAA AGACAGCGCAAGGCCCTGAGCAGAATTTCCTTGTCTCGAATTATATGTGACAATACCGGT ATCACCACGGTTTCAAGGGACATCTTCAGAGCCAACATCTACCCTCGGGGCTTTGTGAAC TGCAGCCGTATCCCCAGGTTGAACCTATCAGCCTGGCGAGGGACATGA Clone variation with respect to NM_000502.4 120 a=>g;366 g=>c;660 a=>g >OriGene 5' read for NM_000502 unedited
NCGTTAGGATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGAAGTGAG AGGTCGGCTGGGGGCCCTCAAGTGAGAGGGGAGCAGAGGATCCTCCCGTGCAGGCTGTGG ATGTCACTCACTTCCCAGCTGGTGAAGCCTCGCTGCAGAGATGCATCTGCTCCCAGCCCT GGCAGGGGTCCTGGCCACACTCGTCCTCGCCCAGCCCTGTGAGGGCACTGACCCAGCCTC CCCTGGGGCAGTGGAGACCTCGGTCCTGCGAGACTGCATGGCAGAGGCCAAGTTGCTGGT GGATGCTGCCTACAATTGGACCCAGAAGAGCATCAAGCAGCGGCTTCGCAGCGGTTCAGC CAGCCCCATGGACCTCCTGTCCTACTTCAAACAACCGGTAGCAGCCACCAGGACAGTTGT TCGGGCCGCAGATTATATGCATGTGGCTTTGGGGCTGCTTGAAGAGAAGTTACAACCCCA GCGGTCCGGACCCTTCAATGTCACTGATGTGCTAACAGAACCACACCTGCGGCTGCTGTC CCAGGCCAGTGGCTGTGCTCTCCGGGACCAGGCCGAGCGCTGCAGCGACAAGTACCGCAC CATCACTGGACGGTGCAACAACAAGAGGAGACCCTTGCTAGGGGCCTCCAACCAGGCTCT GGCTCGCTGGCTGCCCGCCGAGTATGAGGATGGGCTGTCGCTCCCCTTCGGCTGGACCCC CAGCAGGAGGCGCAATGGCTTCCTTCTCCCTCTTGTGCGGGCTGTCTCCACCAGATTGTG CGCTTCCCCAAGAGAGACTGACCTCCGACCGTGGCCGGGCCCTCATGTTCATGCAGTGGN GCCAGTTCATTGACCATGACCTGNNACTTCTCCCGNATCCCCGGNCAGAGTGCCCTCACT GCCAGCGTTGACTGTGAGAGGACTGCGC >OriGene 3' read for NM_000502 unedited
GGGGGGGGGCGGGCCNAACCNNNNCCCTTTTNNNNNNGGNNTTTTACTTGNCCNCGGCCG CTTTTNANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCCCT TAACAGGGCTTTATTGGTAAAAACAAAACATGCTGCCTGGCCTCAAGCTCAAAAGAATAT TGTGGGGGGTCTGGAGGCTAAGACCCAATGGTCTCTTAATCATGGGGAGGGAGGGGAGGG AGGGCTGGGAAACAATAAAAAGGGCTGTAAACCCTCCAACTGACTTTTTTTGCCTGGGGG GCAAAACCACATGGCTTGGCTCCCAAACCTTTGCACGTGGCGCTGATTCATAACCTAATA CCTAAAAGGCTCCCAAGGCGGGAAGGGCCATTGCTGATAAGAACCCCCAACCTTCACTCC TGGCTGGGGAACCCAACTCTGAACTGTAACCAACAAAAACGTCAACAGCCTGCACTTGCT CCAAGGAAACAAGGCAACCTCATGGGCCTCCCCTTCCCCTTGTCTCCAAAAGTTGGAAAC TTGGGATAAACTCCTGCAAAAACCTCATGTCCCTCGCCAGGCTGATAGGGTCAACCTGGG GATACCGCTGCAGTTCACAAAGCCCCCAGGGTAGATGTTGGCTCTTAAGAAGTCCCTTGA AACCCTGGTGATACCGGTATTGTCACATATAATTCGAGACAAAGAAATTCTGCTCAAGGC CTTGCGCTGTCTTTTGGTGAAAACACCTCGTTTCTGCCACCAGAACCTGTCTTCCTCTCG GGCTCTCCTGAACTGGTTCTCGAACAGAAAGCCAGAAAAGCCCCACTCCACCCCCCGCAA AAAGCTCAACGATGGCCCCATCCAGATGTCATGTTGTCAGGGTTCCATACAAATTAGAAC CTCCTGGCCAACCTGGTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000502 |
| Insert Size | 2680 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000502.2, NP_000493.1 |
| RefSeq Size | 2267 bp |
| RefSeq ORF | 2148 bp |
| Locus ID | 8288 |
| UniProt ID | P11678 |
| Domains | An_peroxidase |
| Protein Families | Druggable Genome |
| Protein Pathways | Asthma |
| Gene Summary | This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218959 | EPX (Myc-DDK-tagged)-Human eosinophil peroxidase (EPX) |
CN¥ 5,240.00 |
|
| RC218959L3 | Lenti-ORF clone of EPX (Myc-DDK-tagged)-Human eosinophil peroxidase (EPX) |
CN¥ 7,700.00 |
|
| RC218959L4 | Lenti-ORF clone of EPX (mGFP-tagged)-Human eosinophil peroxidase (EPX) |
CN¥ 7,700.00 |
|
| RG218959 | EPX (tGFP-tagged) - Human eosinophil peroxidase (EPX) |
CN¥ 6,840.00 |
