SDF1 (CXCL12) (NM_000609) Human Untagged Clone

CAT#: SC119783

CXCL12 (untagged)-Human chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 2



  "NM_000609" in other vectors (6)

CNY 1,800.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
CXCL12 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000609 edited
GAATTCGGCACGAGGGCTCTGCCTCAGCGACGGGAAGCCCGTCAGCCTGAGCTACAGATG
CCCATGCCGATTCTTCGAAAGCCATGTTGCCAGAGCCAACGTCAAGCATCTCAAAATTCT
CAACACTCCAAACTGTGCCCTTCAGATTGTAGCCCGGCTGAAGAACAACAACAGACAAGT
GTGCATTGACCCGAAGCTAAAGTGGATTCAGGAGTACCTGGAGAAAGCTTTAAACAAGTA
AGCACAACAGCCAAAAAGGACTTTCCGCTAGACCCACTCGAGGAAAACTAAAACCTTGTG
AGAGATGAAAGGGCAAAGACGTGGGGGAGAGGGGGCCTTAACCATGAGGACCAGGTGTGT
GTGTGGGGTGGGCACATTGATCTGGGATCGGGCCTGAGGTTTGCCAGCATTTAGACCCTG
CATTTATAGCATACGGTATGATATTGCAGCTTATATTCATCCATGCCCTGTACCTGTGCA
CGTTGGAACTTTTATTACTGGGGTTTTTCTAAGAAAGAAATTGTATTATCAACAGCATTT
TCAAGCAGTTAGTTCCTTCATGATCATCACAATCATCATCATTCTCATTCTCATTTTTTA
AATCAACGAGTACTTCAAGATCTGAATTTGGCTTGTTTGGAGCATCTCCTCTGCTCCCCT
GGGGAGTCTGGGCACAGTCAGGTGGTGGCTTAACAGGGAGCTGGAAAAAGTGTCCTTTCT
TCAGACACTGAGGCTCCCGCAGCAGCGCCCCTCCCAAGAGGAAGGCCTCTGTGGCACTCA
GATACCGACTGGGGCTGGGCGCCGCCACTGCCTTCACCTCCTCTTTCAACCTCAGTGATT
GGCTCTGTGGGCTCCATGTAGAAGCCACTATTACTGGGACTGTGCTCAGAGACCCCTCTC
CCAGCTATTCCTACTCTCTCCCCGACTCCGAGAGCATGCTTAATCTTGCTTCTGCTTCTC
ATTTCTGTAGCCTGAXXXXXXXXXXXXXXXXXXXXXXXCTCGAC
>OriGene 5' read for NM_000609 unedited
GGGTTCACGATGTTGTAACACGATTTACTATAGGGCGGCCGCGCAATTCGCACGAGGGTC
AGCCGCATTGCCCGCTCGGCGTCCGGCCCCCGACCCGCGCTCGTCCGCCCGCCCGCCCGC
CCGCCCGCGCCATGAACGCCAAGGTCGTGGTCGTGCTGGTCCTCGTGCTGACCGCGCTCT
GCCTCAGCGACGGGAAGCCCGTCAGCCTGAGCTACTGATGCCCATGCCGATTCTTCGAAA
GCCATGTTGCCAGAGCCAACGTCAAGCATCTCAAAATTCTCAACACTCCAAACTGTGCCC
TTCAGATTGTAGCCCGGCTGAAGAACAACAACAGACAAGTGTGCATTGACCCGAAGCTAA
AGTGGATTCAGGAGTACCTGGAGAAAGCTTTAAACAAGAGGTTCAAGATGTGAGAGGGTC
AGACGCCTGAGGAACCCTTACAGTAGGAGCCCAGCTCTGAAACCAGTGTTAGGGAAGGGC
CTGCCACAGCCTCCCCTGCCAGGGCAGGGCCCCAGGCATTGCCAAGGGCTTTGTTTTGCA
CACTTTGCCCATATTTTCACCATTTGATTATGTAGCAAAATATATGACATTTATTTTTCA
TTTAGTTCGATTATTTCAGTGTCACTGGCGACACGTAGCAGCTTACACTAAGGCCATTAT
TGTACTTGCCCTTATTAGAGTGCCCTTCCACGGAGCCACTCCTTTGACTCAGGGCTCCTG
GGTTTCGTACTCTCTGAACTGTGCACGTGGAGAGACTGGGCTTCAGGCAGCCTGGCCCCA
TTGTCAGCCCTAGGGTGGAAACCCCCCAAAAGGACACCTCGGGGTGCCCGGAACCATTCA
ACCTGGGCATACCTATTCAAGGTCTCTCTTCGTGGCCAGGATGGGGGCAGGCCCCTGCGA
AGCTCCCCCCCTCCT
>OriGene 3' read for NM_000609 unedited
TGGACCGCGGCCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACATTTGAGTACA
GAACTTTATTAGGAAAATTATAAGTGCATATACATTTTTTCATTGGTATGACTTCAAAGT
AGAAATTGTTGTTTCTCAAAGAGTTGTTTCTTATTTATTTTTTAAAGCACGCTGCGTATA
GGAATTGGCCTTCTCCTGGACCATTTTCACATTATCTGGGAGATGCAATTGAAACAATAC
AAAATACAGTATTCATCACATTTAACACTGAATCATTCACTGCTCAGAGACTGAGAGTCC
AGCGAGGTTGCAAAATAACAAATTTTCTACATGGTTTTATCAGTGGTCTGCTTAGGGGAT
TTGGAAGTTTCTAGGGAATATTTCCCAGGAATGGGGCTCCTTCAGAATGAGTCAGGGAAG
CTCTGTAGAGGGATCAGAGCACTCAAATTCTCATCCAGCTGGAAAAGGGTGTAGCACCTG
GGAAAGGCGATCAACTCCCAGTCAGGGAGCCCACGGTGATAACACCAGTCAGACGATCAC
ACCATGGAAGGGTCCAATGAGATCCAATGGAAAGACTTAGAACATCTAAGGTTGGGGGAG
GTGCAACCTTCTGCTATTCAGCCCCTCTGCTCCAAGCGGAACCTTTTTTCTCAGGAGGTA
ATCTCTAATAACAAGCAGAGCGCCCTCTGGAGCCTCCTCGCTGGTATCTCAGTGCCTGGA
CAGAGGGGGACACACCACAGCACAAACACGTGGCACAGACTCAATCCCAACACACAGCCA
GTCAACGAGCCTNTGCCCCCTTCCTCTGGGTCCTGAACAGAGCCTGCAGCGAGGGCTCTG
AAGAGGTACAGGTAGCCCAGGCAGTGTTAGGTATAGCCACACCAGTCCCGGAGGACAGAG
AAGCACCCTATAAACACTCGTGGCGCCCTGN
Restriction Sites NotI-NotI     
ACCN NM_000609
Insert Size 3520 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000609.3, NP_000600.1
RefSeq Size 3560 bp
RefSeq ORF 282 bp
Locus ID 6387
UniProt ID P48061
Domains IL8
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration
Gene Summary This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Transcript Variant: This variant (2) contains an alternate exon, and differs in the 3' coding region and UTR compared to variant 1. The resulting protein (isoform beta) is longer and has a distinct C-terminus compared to isoform alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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