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CD14 (NM_000591) Human Untagged Clone
CAT＃: SC119773
CD14 (untagged)-Human CD14 molecule (CD14), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119773 sequence for NM_000591 edited (data generated by NextGen Sequencing)
ATGGAGCGCGCGTCCTGCTTGTTGCTGCTGCTGCTGCCGCTGGTGCACGTCTCTGCGACC ACGCCAGAACCTTGTGAGCTGGACGATGAAGATTTCCGCTGCGTCTGCAACTTCTCCGAA CCTCAGCCCGACTGGTCCGAAGCCTTCCAGTGTGTGTCTGCAGTAGAGGTGGAGATCCAT GCCGGCGGTCTCAACCTAGAGCCGTTTCTAAAGCGCGTCGATGCGGACGCCGACCCGCGG CAGTATGCTGACACGGTCAAGGCTCTCCGCGTGCGGCGGCTCACAGTGGGAGCCGCACAG GTTCCTGCTCAGCTACTGGTAGGCGCCCTGCGTGTGCTAGCGTACTCCCGCCTCAAGGAA CTGACGCTCGAGGACCTAAAGATAACCGGCACCATGCCTCCGCTGCCTCTGGAAGCCACA GGACTTGCACTTTCCAGCTTGCGCCTACGCAACGTGTCGTGGGCGACAGGGCGTTCTTGG CTCGCCGAGCTGCAGCAGTGGCTCAAGCCAGGCCTCAAGGTACTGAGCATTGCCCAAGCA CACTCGCCTGCCTTTTCCTGCGAACAGGTTCGCGCCTTCCCGGCCCTTACCAGCCTAGAC CTGTCTGACAATCCTGGACTGGGCGAACGCGGACTGATGGCGGCTCTCTGTCCCCACAAG TTCCCGGCCATCCAGAATCTAGCGCTGCGCAACACAGGAATGGAGACGCCCACAGGCGTG TGCGCCGCACTGGCGGCGGCAGGTGTGCAGCCCCACAGCCTAGACCTCAGCCACAACTCG CTGCGCGCCACCGTAAACCCTAGCGCTCCGAGATGCATGTGGTCCAGCGCCCTGAACTCC CTCAATCTGTCGTTCGCTGGGCTGGAACAGGTGCCTAAAGGACTGCCAGCCAAGCTCAGA GTGCTCGATCTCAGCTGCAACAGACTGAACAGGGCGCCGCAGCCTGACGAGCTGCCCGAG GTGGATAACCTGACACTGGACGGGAATCCCTTCCTGGTCCCTGGAACTGCCCTCCCCCAC GAGGGCTCAATGAACTCCGGCGTGGTCCCAGCCTGTGCACGTTCGACCCTGTCGGTGGGG GTGTCGGGAACCCTGGTGCTGCTCCAAGGGGCCCGGGGCTTTGCCTAA Clone variation with respect to NM_000591.3 >OriGene 5' read for NM_000591 unedited
CGACTCACTATAGGGCGGCCGCGAATTCGGCACCGAGGGAAGAGTTCACAAGTGTGAAGC CTGGAAGCCGGCGGGTGCCGCTGTGTAGGAAAGAAGCTAAAGCACTTCCAGAGCCTGTCC GGAGCTCAGAGGTTCGGAAGACTTATCGACCATGGAGCGCGCGTCCTGCTTGTTGCTGCT GCTGCTGCCGCTGGTGCACGTCTCTGCGACCACGCCAGAACCTTGTGAGCTGGACGATGA AGATTTCCGCTGCGTCTGCAACTTCTCCGAACCTCAGCCCGACTGGTCCGAAGCCTTCCA GTGTGTGTCTGCAGTAGAGGTGGAGATCCATGCCGGCGGTCTCAACCTAGAGCCGTTTCT AAAGCGCGTCGATGCGGACGCCGACCCGCGGCAGTATGCTGACACGGTCAAGGCTCTCCG CGTGCGGCGGCTCACAGTGGGAGCCGCACAGGTTCCTGCTCAGCTACTGGTAGGCGCCCT GCGTGTGCTAGCGTACTCCCGCCTCAAGGAACTGACGCTCGAGGACCTANAGATAACCGG CACCATGCCTCCGCTGCCTCTGGAAGCCACAGGACTTGCACTTTCCAGCTTGCGCCTACG CAACGTGTCGTGGGCGACAGGGCGTTCTTGGCTCGCCGAGCTGCAGCAGTGGCTCAAGCC AGCCCTCAGGTACTGAGCATTGCCCAGCACACTCGCCTGCCTTTTTCTGCGAACAGTTTC GCGCCCTTCCCGGCCCTTACCAGNCTAGACCTGTCCTGACATCCTGGACTGGGCGAAACG CGGACTGATGGCNGNTCCTCTGTCCCCACCAGTTCCCGGCCATCCAGAATCTAGCGCTGC GCAACACAGGGATTGAAGACGCCCACAGGGTGTTCCGCCGACCTGGCCGNGTAAGGTGTG CACCCCCCAAGCCTAACCTCAGCCCAACTGGCTGCCGCCACCGTAAACCTACCGTCGAGA AGCTGGGCCCACCGCCTAACTCCTAAT >OriGene 3' read for NM_000591 unedited
CCGGTNCGAAAAGTCCTCAACGTCCTGACGGGACTCCCCTGAACCAAGCAGTTTGAGTCC ATTCATTATTCTGTCTTGGATCTTAGGCAAAGCCCCGGGCCCCTTGGAGCAGCACCAGGG TTCCCGACACCCCCACCGACAGGGTCGAACGTGCACAGGCTGGGACCACGCCTGATTTTA TTGAGCCCTCGTGGGGGAGGGCAGTTCCAGGGACCAGGAAGGGATTCCCGTCCAGTGTCA GGTTATCCACCTCGGGCAGCTCGTCAGGCTGCGGCGCCCTGTTCAGTCTGTTGCAGCTGA GATCGAGCACTCTGAGCTTGGCTGGCAGTCCTTTAGGCACCTGTTCCAGCCCAGCGAACG ACAGATTGAGGGAGTTCAGGGCGCTGGACCACATGCATCTCGGAGCGCTAGGGTTTACGG TGGCGCGCAGCGAGTTGTGGCTGAAGTCTAGGCTGTGGGGCTGCACACCTGCCGCCGCCA GTGCGGCGCACACGCCTGTGGGCGTCTCCATTCCTGTGTTGCGCAGCGCTAGATTCTGGA TGGCCGGGAACTTGTGGGGACAGAGAGCCGCCATCAGTCCGCGTTCGCCCAGTCCAGGAT TGTCAGACAGGTCTAGGCTGGTAAGGGCCGGGAAGGCGCGAACCTGTTCGCAGGATAAGG CAGGCGAGTGTGCTTGGGCAATGCTCAGTACCTTGAGGCCTGGCTTGAGCCACTGCTGCA GCTCGGCGAGCCAAGAACGCCCTGTCGCCCACGACACGTTGCGTATGCGCAAGCTGGAAA GTGCAAGTCCTGTGGCTTCCANAGCAGCGGAGGCATGGTGCCGGTTATCTTTTAGTCCTC GAGCGTCAGTTCCTTTGAGCG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_000591 |
| Insert Size | 1330 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000591.1, NP_000582.1 |
| RefSeq Size | 1367 bp |
| RefSeq ORF | 1128 bp |
| Locus ID | 929 |
| UniProt ID | P08571 |
| Domains | LRR |
| Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] Transcript Variant: This variant (1) represents the predominant transcript. Variants 1-4 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Single Amino Acid of Toll-like Receptor 4 That Is Pivotal for Its Signal Transduction and Subcellular Localization
,Shintaro Yanagimoto, Keita Tatsuno, Shu Okugawa, Takatoshi Kitazawa, Kunihisa Tsukada, Kazuhiko Koike, Tatsuhiko Kodama, Satoshi Kimura, Yoshikazu Shibasaki, and Yasuo Ota,
J. Biol. Chem., Feb 2009; 284: 3513 - 3520.
[CD14]
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Other Versions
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|---|---|---|---|
| RC203819 | CD14 (Myc-DDK-tagged)-Human CD14 molecule (CD14), transcript variant 1 |
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| RC203819L1 | Lenti ORF clone of Human CD14 molecule (CD14), transcript variant 1, Myc-DDK-tagged |
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| RC203819L2 | Lenti ORF clone of Human CD14 molecule (CD14), transcript variant 1, mGFP tagged |
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| RC203819L3 | Lenti ORF clone of Human CD14 molecule (CD14), transcript variant 1, Myc-DDK-tagged |
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| RC203819L4 | Lenti ORF clone of Human CD14 molecule (CD14), transcript variant 1, mGFP tagged |
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| RG203819 | CD14 (tGFP-tagged) - Human CD14 molecule (CD14), transcript variant 1 |
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| SC323734 | CD14 (untagged)-Human CD14 molecule (CD14), transcript variant 1 |
CNY 5,488.00 |
