ADH4 (NM_000670) Human Untagged Clone
CAT#: SC119754
ADH4 (untagged)-Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ADH-2; HEL-S-4 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119754 sequence for NM_000670 edited (data generated by NextGen Sequencing)
ATGGGCACCAAGGGCAAAGTTATTAAATGCAAAGCAGCCATCGCCTGGGAAGCAGGCAAG CCCCTTTGCATTGAAGAGGTTGAAGTAGCTCCCCCCAAGGCTCATGAAGTTCGCATTCAG ATCATTGCTACCTCCCTGTGCCATACTGATGCCACTGTTATCGATTCTAAATTTGAGGGC CTAGCTTTCCCAGTGATCGTTGGCCATGAGGCTGCAGGTATTGTGGAAAGTATTGGGCCA GGAGTGACCAACGTCAAACCAGGTGACAAAGTAATTCCACTTTATGCACCTCTATGTAGA AAATGCAAGTTTTGTCTGAGTCCACTCACAAATTTGTGTGGGAAAATCAGTAATCTCAAA AGTCCTGCTAGTGATCAACAACTAATGGAAGACAAAACCAGCAGGTTTACCTGCAAAGGA AAACCAGTTTACCATTTCTTTGGAACCAGTACATTCTCTCAGTACACTGTGGTGTCAGAT ATCAATCTTGCCAAAATAGATGATGATGCAAATTTAGAGAGAGTTTGTCTGCTTGGATGT GGGTTTTCAACTGGCTATGGGGCTGCAATCAACAATGCCAAGGTCACCCCTGGTTCGACT TGTGCTGTCTTTGGCCTAGGAGGTGTGGGTCTTTCTGCTGTAATGGGTTGTAAAGCAGCA GGAGCTTCCAGAATCATAGGTATTGACATCAACAGTGAGAAGTTTGTGAAGGCTAAAGCC CTGGGAGCCACTGACTGCCTCAATCCTAGAGACTTACATAAACCTATCCAGGAAGTTATC ATTGAATTGACCAAGGGAGGTGTGGATTTTGCCCTTGACTGTGCAGGTGGATCTGAAACC ATGAAAGCAGCCCTGGACTGTACAACCGCAGGCTGGGGATCATGTACTTTCATTGGAGTA GCTGCTGGTAGCAAAGGATTGACTGTTTTTCCAGAGGAGCTAATAATCGGCCGTACTATA AATGGAACATTCTTTGGTGGTTGGAAAAGTGTAGATTCTATCCCAAAGCTGGTCACTGAC TATAAGAATAAGAAATTCAATCTGGATGCACTGGTGACCCATACCCTGCCTTTTGACAAA ATCAGTGAGGCATTTGACCTAATGAACCAAGGAAAAAGCATCCGAACAATCCTCATCTTT TGA Clone variation with respect to NM_000670.3 765 g=>t;925 a=>g;1120 g=>a >OriGene 5' read for NM_000670 unedited
GTAATACGACTCACTATAGGGCGGCCGCGCAGTTTCCCAAAAAAAAAGGGCACCAAGGGC AAAGTTATTAAATGCAAAGCAGCCATCGCCTGGGAAGCAGGCAAGCCCCTTTGCATTGAA GAGGTTGAAGTAGCTCCCCCCAAGGCTCATGAAGTTCGCATTCAGATCATTGCTACCTCC CTGTGCCATACTGATGCCACTGTTATCGATTCTAAATTTGAGGGCCTAGCTTTCCCAGTG ATCGTTGGCCATGAGGCTGCAGGTATTGTGGAAAGTATTGGGCCAGGAGTGACCAACGTC AAACCAGGTGACAAAGTAATTCCACTTTATGCACCTCTATGTAGAAAATGCAAGTTTTGT CTGAGTCCACTCACAAATTTGTGTGGGAAAATCAGTAATCTCAAAAGTCCTGCTAGTGAT CAACAACTAATGGAAGACAAAACCAGCAGGTTTACCTGCAAAGGAAAACCAGTTTACCAT TTCTTTGGAACCAGTACATTCTCTCAGTACACTGTGGTGTCAGATATCAATCTTGCCAAA ATAGATGATGATGCANATNTAGAGAGAGTTTGTCTGCTTGGATGTGGGTTTTCAACTGGC TATGGNGCTGNCATCAAACATGCCAAGGTCACCCCTGGNTCGACTTGTGCTGTCTTTGCC TANNGAGTGTGGGTCTTTCTGCTGTAATGGNTNGTAAAGCAGCAGGAGCTTCCAGAATCA TAGGTATTGACATCAACAGTGAGAAGTTTGTGAAGGCTAANAGCCCTGGACCACTGACTG CCTCCATCCTAGAGACTTACATANACCTATNCCAGAAAGTATCATTGAAATGACCAGGGN ANGGTGTGATNNTGCCCTTGACTGTGCNAGTGGATCTGAAACCATAAGGCAGNCCTGNAC TGTACACCGCNAGCTGGGATCATGTATTNCATTGNNATACTGCTGGTACAAAGATGACTT GTTTCCAAGACTAAAATCGNCGACTTTAATGGCTTCTTGGTGTTGAAAGGTAATCTACCC ACTGGCCTGCCTAAAAGAAATTATGGGTCTGGGACCACCTGCTTGAN >OriGene 3' read for NM_000670 unedited
TTTTTTTTTTTTTTTTTTTTTT |
Restriction Sites | NotI-NotI |
ACCN | NM_000670 |
Insert Size | 2100 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000670.3, NP_000661.2 |
RefSeq Size | 1980 bp |
RefSeq ORF | 1143 bp |
Locus ID | 127 |
UniProt ID | P08319 |
Domains | ADH_zinc_N |
Protein Families | Druggable Genome |
Protein Pathways | Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism |
Gene Summary | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the 5' coding region, which results in use of an alternate start codon compared to variant 1. It encodes isoform 2, which is shorter than and has a novel N-terminus compared to isoform 1. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204750 | ADH4 (Myc-DDK-tagged)-Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4) |
CNY 3,656.00 |
|
RC204750L1 | Lenti ORF clone of Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC204750L2 | Lenti ORF clone of Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), mGFP tagged |
CNY 5,890.00 |
|
RC204750L3 | Lenti ORF clone of Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204750L4 | Lenti ORF clone of Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), mGFP tagged |
CNY 5,890.00 |
|
RG204750 | ADH4 (tGFP-tagged) - Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4) |
CNY 5,256.00 |
|
SC320964 | ADH4 (untagged)-Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4) |
CNY 3,656.00 |