ADH4 (NM_000670) Human Untagged Clone

CAT#: SC119754

ADH4 (untagged)-Human alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4)



  "NM_000670" in other vectors (7)

CNY 3,656.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Anti-ADH4 Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ADH-2; HEL-S-4
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119754 sequence for NM_000670 edited (data generated by NextGen Sequencing)
ATGGGCACCAAGGGCAAAGTTATTAAATGCAAAGCAGCCATCGCCTGGGAAGCAGGCAAG
CCCCTTTGCATTGAAGAGGTTGAAGTAGCTCCCCCCAAGGCTCATGAAGTTCGCATTCAG
ATCATTGCTACCTCCCTGTGCCATACTGATGCCACTGTTATCGATTCTAAATTTGAGGGC
CTAGCTTTCCCAGTGATCGTTGGCCATGAGGCTGCAGGTATTGTGGAAAGTATTGGGCCA
GGAGTGACCAACGTCAAACCAGGTGACAAAGTAATTCCACTTTATGCACCTCTATGTAGA
AAATGCAAGTTTTGTCTGAGTCCACTCACAAATTTGTGTGGGAAAATCAGTAATCTCAAA
AGTCCTGCTAGTGATCAACAACTAATGGAAGACAAAACCAGCAGGTTTACCTGCAAAGGA
AAACCAGTTTACCATTTCTTTGGAACCAGTACATTCTCTCAGTACACTGTGGTGTCAGAT
ATCAATCTTGCCAAAATAGATGATGATGCAAATTTAGAGAGAGTTTGTCTGCTTGGATGT
GGGTTTTCAACTGGCTATGGGGCTGCAATCAACAATGCCAAGGTCACCCCTGGTTCGACT
TGTGCTGTCTTTGGCCTAGGAGGTGTGGGTCTTTCTGCTGTAATGGGTTGTAAAGCAGCA
GGAGCTTCCAGAATCATAGGTATTGACATCAACAGTGAGAAGTTTGTGAAGGCTAAAGCC
CTGGGAGCCACTGACTGCCTCAATCCTAGAGACTTACATAAACCTATCCAGGAAGTTATC
ATTGAATTGACCAAGGGAGGTGTGGATTTTGCCCTTGACTGTGCAGGTGGATCTGAAACC
ATGAAAGCAGCCCTGGACTGTACAACCGCAGGCTGGGGATCATGTACTTTCATTGGAGTA
GCTGCTGGTAGCAAAGGATTGACTGTTTTTCCAGAGGAGCTAATAATCGGCCGTACTATA
AATGGAACATTCTTTGGTGGTTGGAAAAGTGTAGATTCTATCCCAAAGCTGGTCACTGAC
TATAAGAATAAGAAATTCAATCTGGATGCACTGGTGACCCATACCCTGCCTTTTGACAAA
ATCAGTGAGGCATTTGACCTAATGAACCAAGGAAAAAGCATCCGAACAATCCTCATCTTT
TGA

Clone variation with respect to NM_000670.3
765 g=>t;925 a=>g;1120 g=>a
>OriGene 5' read for NM_000670 unedited
GTAATACGACTCACTATAGGGCGGCCGCGCAGTTTCCCAAAAAAAAAGGGCACCAAGGGC
AAAGTTATTAAATGCAAAGCAGCCATCGCCTGGGAAGCAGGCAAGCCCCTTTGCATTGAA
GAGGTTGAAGTAGCTCCCCCCAAGGCTCATGAAGTTCGCATTCAGATCATTGCTACCTCC
CTGTGCCATACTGATGCCACTGTTATCGATTCTAAATTTGAGGGCCTAGCTTTCCCAGTG
ATCGTTGGCCATGAGGCTGCAGGTATTGTGGAAAGTATTGGGCCAGGAGTGACCAACGTC
AAACCAGGTGACAAAGTAATTCCACTTTATGCACCTCTATGTAGAAAATGCAAGTTTTGT
CTGAGTCCACTCACAAATTTGTGTGGGAAAATCAGTAATCTCAAAAGTCCTGCTAGTGAT
CAACAACTAATGGAAGACAAAACCAGCAGGTTTACCTGCAAAGGAAAACCAGTTTACCAT
TTCTTTGGAACCAGTACATTCTCTCAGTACACTGTGGTGTCAGATATCAATCTTGCCAAA
ATAGATGATGATGCANATNTAGAGAGAGTTTGTCTGCTTGGATGTGGGTTTTCAACTGGC
TATGGNGCTGNCATCAAACATGCCAAGGTCACCCCTGGNTCGACTTGTGCTGTCTTTGCC
TANNGAGTGTGGGTCTTTCTGCTGTAATGGNTNGTAAAGCAGCAGGAGCTTCCAGAATCA
TAGGTATTGACATCAACAGTGAGAAGTTTGTGAAGGCTAANAGCCCTGGACCACTGACTG
CCTCCATCCTAGAGACTTACATANACCTATNCCAGAAAGTATCATTGAAATGACCAGGGN
ANGGTGTGATNNTGCCCTTGACTGTGCNAGTGGATCTGAAACCATAAGGCAGNCCTGNAC
TGTACACCGCNAGCTGGGATCATGTATTNCATTGNNATACTGCTGGTACAAAGATGACTT
GTTTCCAAGACTAAAATCGNCGACTTTAATGGCTTCTTGGTGTTGAAAGGTAATCTACCC
ACTGGCCTGCCTAAAAGAAATTATGGGTCTGGGACCACCTGCTTGAN
>OriGene 3' read for NM_000670 unedited
TTTTTTTTTTTTTTTTTTTTTT
Restriction Sites NotI-NotI     
ACCN NM_000670
Insert Size 2100 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000670.3, NP_000661.2
RefSeq Size 1980 bp
RefSeq ORF 1143 bp
Locus ID 127
UniProt ID P08319
Domains ADH_zinc_N
Protein Families Druggable Genome
Protein Pathways Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism
Gene Summary This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the 5' coding region, which results in use of an alternate start codon compared to variant 1. It encodes isoform 2, which is shorter than and has a novel N-terminus compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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