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ALDH1A3 (NM_000693) Human Untagged Clone
CAT＃: SC119706
ALDH1A3 (untagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3)
CNY 3,824.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALDH1A6; ALDH6; MCOP8; RALDH3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000693 edited
ATGGCCACCGCTAACGGGGCCGTGGAAAACGGGCAGCCGGACAGGAAGCCGCCGGCCCTG CCGCGCCCCATCCGCAACCTGGAGGTCAAGTTCACCAAGATATTTATCAACAATGAATGG CACGAATCCAAGAGTGGGAAAAAGTTTGCTACATGTAACCCTTCAACTCGGGAGCAAATA TGTGAAGTGGAAGAAGGAGATAAGCCCGACGTGGACAAGGCTGTGGAGGCTGCACAGGTT GCCTTCCAGAGGGGCTCGCCATGGCGCCGGCTGGATGCCCTGAGTCGTGGGCGGCTGCTG CACCAGCTGGCTGACCTGGTGGAGAGGGACCGCGCCACCTTGGCCGCCCTGGAGACGATG GATACAGGGAAGCCATTTCTTCATGCTTTTTTCATCGACCTGGAGGGCTGTATTAGAACC CTCAGATACTTTGCAGGGTGGGCAGACAAAATCCAGGGCAAGACCATCCCCACAGATGAC AACGTCGTGTGCTTCACCAGGCATGAGCCCATTGGTGTCTGTGGGGCCATCACTCCATGG AACTTCCCCCTGCTGATGCTGGTGTGGAAGCTGGCACCCGCCCTCTGCTGTGGGAACACC ATGGTCCTGAAGCCTGCGGAGCAGACACCTCTCACCGCCCTTTATCTCGGCTCTCTGATC AAAGAGGCCGGGTTCCCTCCAGGAGTGGTGAACATTGTGCCAGGATTCGGGCCCACAGTG GGAGCAGCAATTTCTTCTCACCCTCAGATCAACAAGATCGCCTTCACCGGCTCCACAGAG GTTGGAAAACTGGTTAAAGAAGCTGCGTCCCGGAGCAATCTGAAGCGGGTGACGCTGGAG CTGGGGGGGAAGAACCCCTGCATCGTGTGTGCGGACGCTGACTTGGACTTGGCAGTGGAG TGTGCCCATCAGGGAGTGTTCTTCAACCAAGGCCAGTGTTGCACGGCAGCCTCCAGGGTG TTCGTGGAGGAGCAGGTCTACTCTGAGTTTGTCAGGCGGAGCGTGGAGTATGCCAAGAAA CGGCCCGTGGGAGACCCCTTCGATGTCAAAACAGAACAGGGGCCTCAGATTGATCAAAAG CAGTTCGACAAAATCTTAGAGCTGATCGAGAGTGGGAAGAAGGAAGGGGCCAAGCTGGAA TGCGGGGGCTCAGCCATGGAAGACAAGGGGCTCTTCATCAAACCCACTGTCTTCTCAGAA GTCACAGACAACATGCGGATTGCCAAAGAGGAGATTTTCGGGCCAGTGCAACCAATACTG AAGTTCAAAAGTATCGAAGAAGTGATAAAAAGAGCGAATAGCACCGACTATGGACTCACA GCAGCCGTGTTCACAAAAAATCTCGACAAAGCCCTGAAGTTGGCTTCTGCCTTAGAGTCT GGAACGGTCTGGATCAACTGCTACAACGCCCTCTATGCACAGGCTCCATTTGGTGGCTTT AAAATGTCAGGAAATGGCAGAGAACTAGGTGAATACGCTTTGGCCGAATACACAGAAGTG AAAACTGTCACCATCAAACTTGGCGACAAGAACCCCTGA >OriGene 5' read for NM_000693 unedited
GCCGCGAATTCGGCACGAGAGCCGGTGCGCCGCAGACTAGGGCGCCTCGGGCCAGGGAGC GCGGAGGAGCCATGGCCACCGCTAACGGGGCCGTGGAAAACGGGCAGCCGGACAGGAAGC CGCCGGCCCTGCCGCGCCCCATCCGCAACCTGGAGGTCAAGTTCACCAAGATATTTATCA ACAATGAATGGCACGAATCCAAGAGTGGGAAAAAGTTTGCTACATGTAACCCTTCAACTC GGGAGCAAATATGTGAAGTGGAAGAAGGAGATAAGCCCGACGTGGACAAGGCTGTGGAGG CTGCACAGGTTGCCTTCCAGAGGGGCTCGCCATGGCGCCGGCTGGATGCCCTGAGTCGTG GGCGGCTGCTGCACCAGCTGGCTGACCTGGTGGAGAGGGACCGCGCCACCTTGGCCGCCC TGGAGACGATGGATACAGGGAAGCCATTTCTTCATGCTTTTTTCATCGACCTGGAGGGCT GTATTAGAACCCTCAGATACTTTGCAGGGTGGGCAGACAAAATCCAGGGCAAGACCATCC CCACAGATGACAANCGTCGTGTGCTTCACCAGGCATGAGCCCATTGGTGTCTGTGGGGCC ATCACTCCATGGGAACTTCCCCTGCTGATGCTGGTGTGGAAGCTGGCACCCGCCCTCTGC TGTGGGAACACCATGGTCCTGAAGCCTGCGGAGCAGACACCTCTCACCGCCCTTTATCTC G >OriGene 3' read for NM_000693 unedited
AGCTCTGNNACCGCGGCCGCATNCTAGNGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTCTCAAATATCCAATTTTATTTTATCATTCTCGCATTGGGGGATGCGATCTGCA GCTAGGATCGGAATTCCCAGGCCTATAGATTTTTAAACCACACCACAGGGGTAAACCTTA AAAAAAGGGAAACCTAACACTATATATATTTCCATTTCTAAATACAGTATATTACAGAAG TTTAAATATACCACCTTTGGGTACTTACAACTATAAAAAGATACAATAACTCTACCAATT ATAAATAATGTAGCATTTCATATTAAAGACATTATCGTACAATGGAAAAATAGGAACCCT CTAACGTATCACTATCAAGGTTAGGGTCTATATCTACTTGAGATAAAATACTGAAAATTC AGGGTATGAAGCCAAATCCTGATTTAACAAGTTATTGGTAGTATAAGGGATAAGGGTTAG CTGATGAAGGGAAGGCAAATGTGGTAATTTATATCTCTGACAAGGGTGATAGGCCCATTT TATACATGGTTTTCGTTATACACACACTGGTTCTGTTACGGGCCCTCATTTTATTATTGC CCTCCCCAACTTAATTTGCAAACTTAAGCACTACTTTCCCCATAGGAAAGTCCTAGTTAG TACCCATAAAAGTATCCGCCGGATAACACATTGGTTTTTGTTTTTGAAGCTTTTGGGGAC CCTTTAAGTTTCCAAGGTAAAACTGAAAATGCCCACATCTTTGGGACCCCCAAGAGAAAA AAAAATTCCACCCTGCCGGGGAAAATTCGGGCCCTTGGAGAAGACCGAGGCCTCCTAAAA CCGGGGGTTTTACTACCTCTCAAATTAATTCAAACGGCCTAAAATAACGGGGTGGTTATC CGCCACCTTTCCCGGGGGCCCCTTCCAAATCAATGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000693 |
| Insert Size | 3200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000693.1, NP_000684.1 |
| RefSeq Size | 3442 bp |
| RefSeq ORF | 1539 bp |
| Locus ID | 220 |
| UniProt ID | P47895 |
| Domains | aldedh |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism |
| Gene Summary | This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells
,Sarvi, S;Crispin, R;Lu, Y;Zeng, L;Hurley, TD;Houston, DR;von Kriegsheim, A;Chen, CH;Mochly-Rosen, D;Ranzani, M;Mathers, ME;Xu, X;Xu, W;Adams, DJ;Carragher, NO;Fujita, M;Schuchter, L;Unciti-Broceta, A;Brunton, VG;Patton, EE;,
Cell Chem Biol
,PubMed ID 30293938
[ALDH1A3]
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Aldehyde dehydrogenase activity plays no functional role in stem cell-like properties in anaplastic thyroid cancer cell lines
,Shimamura, M;Kurashige, T;Mitsutake, N;Nagayama, Y;,
Endocrine
,PubMed ID 28040834
[ALDH1A3]
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Concerted Action of Aldehyde Dehydrogenases Influences Depot-Specific Fat Formation
,Barbara Reichert, Rumana Yasmeen, Shanmugam M. Jeyakumar, Fangping Yang, Thomas Thomou, Hansjuerg Alder, Gregg Duester, Andrei Maiseyeu, Georgeta Mihai, Earl H. Harrison, Sanjay Rajagopalan, James L. Kirkland, and Ouliana Ziouzenkova,
Mol. Endocrinol., May 2011; 25: 799 - 809
[Aldh1a3]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209656 | ALDH1A3 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 3,816.00 |
|
| RC209656L1 | Lenti-ORF clone of ALDH1A3 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 6,216.00 |
|
| RC209656L2 | Lenti-ORF clone of ALDH1A3 (mGFP-tagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 6,460.00 |
|
| RC209656L3 | Lenti-ORF clone of ALDH1A3 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 6,460.00 |
|
| RC209656L4 | Lenti-ORF clone of ALDH1A3 (mGFP-tagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 6,216.00 |
|
| RG209656 | ALDH1A3 (tGFP-tagged) - Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3) |
CNY 5,416.00 |
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