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CYP11A1 (NM_000781) Human Untagged Clone
CAT＃: SC119684
CYP11A1 (untagged)-Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 3,888.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYP11A; CYPXIA1; P450SCC |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000781 edited
TTCGCACCAGGCAGGTACAGTCACAGCTGTGGGGACAGCATGCTGGCCAAGGGTCTTCCC CCACGCTCAGTCCTGGTCAAAGGCTGCCAGACCTTTCTGAGTGCCCCCAGGGAGGGGCTG GGGCGTCTCAGGGTGCCCACTGGCGAGGGAGCTGGCATCTCCACCCGCAGTCCTCGCCCC TTCAATGAGATCCCCTCTCCTGGTGACAATGGCTGGCTAAACCTGTACCATTTCTGGAGG GAGACGGGCACACACAAAGTCCACCTTCACCATGTCCAGAATTTCCAGAAGTATGGCCCG ATTTACAGGGAGAAGCTCGGCAACGTGGAGTCGGTTTATGTCATCGACCCTGAAGATGTG GCCCTTCTCTTTAAGTCCGAGGGCCCCAACCCAGAACGATTCCTCATCCCGCCCTGGGTC GCCTATCACCAGTATTACCAGAGACCCATAGGAGTCCTGTTGAAGAAGTCGGCAGCCTGG AAGAAAGACCGGGTGGCCCTGAACCAGGAGGTGATGGCTCCAGAGGCCACCAAGAACTTT TTGCCCCTGTTGGATGCAGTGTCTCGGGACTTCGTCAGTGTCCTGCACAGGCGCATCAAG AAGGCGGGCTCCGGAAATTACTCGGGGGACATCAGTGATGACCTGTTCCGCTTTGCCTTT GAGTCCATCACTAACGTCATTTTTGGGGAGCGCCAGGGGATGCTGGAGGAAGTAGTGAAC CCCGAGGCCCAGCGATTCATTGATGCCATCTACCAGATGTTCCACACCAGCGTCCCCATG CTCAACCTTCCCCCAGACCTGTTCCGTCTGTTCAGGACCAAGACCTGGAAGGACCATGTG GCTGCATGGGACGTGATTTTCAGTAAAGCTGACATATACACCCAGAACTTCTACTGGGAA TTGAGACAGAAAGGAAGTGTTCACCACGATTACCGTGGCATCCTCTACAGACTCCTGGGA GACAGCAAGATGTCCTTCGAGGACATCAAGGCCAACGTCACAGAGATGCTGGCAGGAGGG GTGGACACGACGTCCATGACCCTGCAGTGGCACTTGTATGAGATGGCACGCAACCTGAAG GTGCAGGATATGCTGCGGGCAGAGGTCTTGGCTGCGCGGCACCAGGCCCAGGGAGACATG GCCACGATGCTACAGCTGGTCCCCCTCCTCAAAGCCAGCATCAAGGAGACACTAAGACTT CACCCCATCTCCGTGACCCTGCAGAGATATCTTGTAAATGACTTGGTTCTTCGAGATTAC ATGATTCCTGCCAAGACACTGGTGCAAGTGGCCATCTATGCTCTGGGCCGAGAGCCCACC TTCTTCTTCGACCCGGAAAATTTTGACCCAACCCGATGGCTGAGCAAAGACAAGAACATC ACCTACTTCCGGAACTTGGGCTTTGGCTGGGGTGTGCGGCAGTGTCTGGGACGGCGGATC GCTGAGCTAGAGATGACCATCTTCCTCATCAATATGCTGGAGAACTTCAGAGTTGAAATC CAACACCTCAGCGATGTGGGCACCACATTCAACCTCATTCTGATGCCTGAAAAGCCCATC TCCTTCACCTTCTGGCCCTTTAACCAGGAAGCAACCCAGCAGTGATCAGAGAGGATGGCC TGCAGCCACATGGGAGGAAGGCCCAGGGGTGGGGCCCATGGGGTCTCTGCATCTTCAGTC GTCTGTCCCAAGTCCTGCTCCTTTCTGCCCAGCCTGCTCAGCAGGTTGAATGGGTTCTCA GTGGTCACCTTCCTCAGCTCAGCTGGGCCACTCCTCTTCACCCACCCCAGGAGACAATAA ACAGCTGAACCATGAAAAAAAAAAAAAAAAAAC >OriGene 5' read for NM_000781 unedited
TATTTTGTAATACGACTCACTATAGAGGCGGCCGCGAATTCGCACCAGGCAGGTACAGTC ACAGCTGTGGGGACAGCATGCTGGCCAAGGGTCTTCCCCCACGCTCAGTCCTGGTCAAAG GCTGCCAGACCTTTCTGAGTGCCCCCAGGGAGGGGCTGGGGCGTCTCATGGTGCCCACTG GCGAGGGAGCTGGCATCTCCACCCGCAGTCCTCGCCCCTTCAATGAGATCCCCTCTCCTG GTGACAATGGCTGGCTAAACCTGTACCATTTCTGGAGGGAGACGGGCACACACAAAGTCC ACCTTCACCATGTCCAGAATTTCCAGAAGTATGGCCCGATTTACAGGGAGAAGCTCGGCA ACGTGGAGTCGGTTTATGTCATCGACCCTGAAGATGTGGCCCTTCTCTTTAAGTCCGAGG GCCCCAACCCAGAACGATTCCTCATCCCGCCCTGNGTCGCCTATCACCAGTATTACCAGA GACCCATAGGAGTCCTGTTGAAGAAGTCGGCAGCCTGGAAGAAAGACCGGGTGGCCCTGA ACCAGGAGGTGATGGCTCCAGAGGCCACCAAGAACTTTTTGCCCCTGTTGGATGCAGTGT CTCGGGACTTCGTCAGTGTCCTGCACAGGCGCATCAAGATAGCGGGCTCCGGATATTACT CGGNGGACATCAGTGATGACCTGTTCCGCTNTGCCTTTGAGTCCATCACTAACGTCATTN TTGGGGAGCGCCAGGGGATGCTGGNAGAAGTANTGAACCCCGAGGCCAGCGATTCATTGA TGCCATCTACCAGATGTTNCACACCAGCGTNCCCATGCTCAACCTTCCCCAGACCCTGTN NCGTCTGTCAGGACCAGACCTGNAATGACATGNTGCTGCATGGGNACGTGATTTCAGTAA GCTGACTATACACCAGAACTCTACTGGGAATTGAGACGAAGGGANTGTCACACGATACCG TGGCATCTCTAGACTCTGGAGAAGCAGATGTCTTCAGGACTAAGGCACGNCANAATCTGC GNNAGGTGGN >OriGene 3' read for NM_000781 unedited
NCGCATTGTCACTGTTTTTGTCTTCTGGGGTGGGTNGAANAGAGTGGCCCAGCTGAGCTG AGGAAGGTGACCACTGNANAACCCATTCAACCTGCTGAGCAGGCTGGGCAGAAAGGAGCA GGACTTGGGACAGACGACTGAAGATGCAGAGACCCCATGGGCCCCACCCCTGGGCCTTCC TCCCATGTGGCTGCAGGCCATCCTCTCTGATCACTGCTGGGTTGCTTCCTGGTTAAAGGG CCAGAAGGTGAAGGAGATGGGCTTTTCAGGCATCAGAATGAGGTTGAATGTGGTGCCCAC ATCGCTGAGGTGTTGGATTTCAACTCTGAAGTTCTCCAGCATATTGATGAGGAAGATGGT CATCTCTAGCTCAGCGATCCGCCGTCCCAGACACTGCCGCACACCCCAGCCAAAGCCCAA GTTCCGGAAGTAGGTGATGTTCTTGTCTTTGCTCAGCCATCGGGTTGGGTCAAAATTTTC CGGGTCGAAGAAGAAGGTGGGCTCTCGGCCCAGAGCATAGATGGCCACTTGCACCAGTGT CTTGGCAGGAATCATGTAATCTCGAAGAACCAAGTCATTTACAAGATATCTCTGCAGGGT CACGGAGATGGGGTGAAGTCTTAGTGTCTCCTTGATGCTGGCTTTGAGGAGGGGGACCAG CTGTAGCATCGTGGCCATGTCTCCCTGGGCCTGGTGCCGCGCAGCCAAGACCTCTGCCCG CAGCATATCCTGCACCTTCAGGTTGCGTGCCATCTCATACAAGTGCCACTGCAGGGTCAT GGACGTCGTGTCCACCCCTTCTGCCAGCATCTCTGTGACCGTGGCCTTGATGTCCTCGAA GACATTTTGCTGTCTCCCAGNAGTCTGTAGAGGATGCCANCGGTAATCGNGGTGAACACT TCCTTTCTGTCTCATTNCCAGTAGAAGTCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000781 |
| Insert Size | 1840 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000781.1, NP_000772.1 |
| RefSeq Size | 1821 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 1583 |
| UniProt ID | P05108 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450 |
| Protein Pathways | C21-Steroid hormone metabolism, Metabolic pathways |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longer isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Resveratrol Stimulates Cortisol Biosynthesis by Activating SIRT-Dependent Deacetylation of P450scc
,Donghui Li, Eric B. Dammer, and Marion B. Sewer,
Endocrinology, Jul 2012; 153: 3258 - 3268.
[CYP11A1]
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Other Versions
| SKU | Description | Size | Price |
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| RC207121 | CYP11A1 (Myc-DDK-tagged)-Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1 |
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| RC207121L1 | Lenti ORF clone of Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 6,280.00 |
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| RC207121L2 | Lenti ORF clone of Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
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| RC207121L3 | Lenti ORF clone of Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC207121L4 | Lenti ORF clone of Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
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| RG207121 | CYP11A1 (tGFP-tagged) - Human cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 5,480.00 |
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