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Natriuretic Peptide Receptor C (NPR3) (NM_000908) Human Untagged Clone
CAT＃: SC119603
NPR3 (untagged)-Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2
CNY 6,040.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000908, the custom clone sequence may differ by one or more nucleotides
ATGCCGTCTCTGCTGGTGCTCACTTTCTCCCCGTGCGTACTACTCGGCTGGGCGTTGCTGGCCGGCGGCA CCGGTGGCGGTGGCGTTGGCGGCGGCGGCGGTGGCGCGGGCATAGGCGGCGGACGCCAGGAGAGAGAGGC GCTGCCGCCACAGAAGATCGAGGTGCTGGTGTTACTGCCCCAGGATGACTCGTACTTGTTTTCACTCACC CGGGTGCGGCCGGCCATCGAGTATGCTCTGCGCAGCGTGGAGGGCAACGGGACTGGGAGGCGGCTTCTGC CGCCGGGCACTCGCTTCCAGGTGGCTTACGAGGATTCAGACTGTGGGAACCGTGCGCTCTTCAGCTTGGT GGACCGCGTGGCGGCGGCGCGGGGCGCCAAGCCAGACCTTATCCTGGGGCCAGTGTGCGAGTATGCAGCA GCGCCAGTGGCCCGGCTTGCATCGCACTGGGACCTGCCCATGCTGTCGGCTGGGGCGCTGGCCGCTGGCT TCCAGCACAAGGACTCTGAGTACTCGCACCTCACGCGCGTGGCGCCCGCCTACGCCAAGATGGGCGAGAT GATGCTCGCCCTGTTCCGCCACCACCACTGGAGCCGCGCTGCACTGGTCTACAGCGACGACAAGCTGGAG CGGAACTGCTACTTCACCCTCGAGGGGGTCCACGAGGTCTTCCAGGAGGAGGGTTTGCACACGTCCATCT ACAGTTTCGACGAGACCAAAGACTTGGATCTGGAAGACATCGTGCGCAATATCCAGGCCAGTGAGAGAGT GGTGATCATGTGTGCGAGCAGTGACACCATCCGGAGCATCATGCTGGTGGCGCACAGGCATGGCATGACC AGTGGAGACTACGCCTTCTTCAACATTGAGCTCTTCAACAGCTCTTCCTATGGAGATGGCTCATGGAAGA GAGGAGACAAACACGACTTTGAAGCTAAGCAAGCATACTCGTCCCTCCAGACAGTCACTCTACTGAGGAC AGTGAAACCTGAGTTTGAGAAGTTTTCCATGGAGGTGAAAAGTTCAGTTGAGAAACAAGGGCTCAATATG GAGGATTACGTTAACATGTTTGTTGAAGGATTCCACGATGCCATCCTCCTCTACGTCTTGGCTCTACATG AAGTACTCAGAGCTGGTTACAGCAAAAAGGATGGAGGGAAAATTATACAGCAGACTTGGAACAGAACATT TGAAGGTATCGCCGGGCAGGTGTCCATAGATGCCAACGGAGACCGATATGGGGATTTCTCTGTGATTGCC ATGACTGATGTGGAGGCGGGCACCCAGGAGGTTATTGGTGATTATTTTGGAAAAGAAGGTCGTTTTGAAA TGCGGCCGAATGTCAAATATCCTTGGGGCCCTTTAAAACTGAGAATAGATGAAAACCGAATTGTAGAGCA TACAAACAGCTCTCCCTGCAAATCATGTGGCCTAGAAGAATCGGCAGTGACAGGAATTGTCGTGGGGGCT TTACTAGGAGCTGGCTTGCTAATGGCCTTCTACTTTTTCAGGAAGAAATACAGAATAACCATTGAGAGGC GAACCCAGCAAGAAGAAAGTAACCTTGGAAAACATCGGGAATTACGGGAAGATTCCATCAGATCCCATTT TTCAGTAGCTTAG >OriGene 5' read for NM_000908 unedited
TTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACCAGTGNACGCTTCCTCT CTATCTTTTGGCGCATTAGTGAAGGGGGTATTCTATTTTGTTAAAGCGCCCAAGGGGCGC AGGGACCTTGGAGAGAAGAGTGGGGAGGAAAGAGGAAGGGCGGGTGGGGGGCAGAGGGCG ATTCGGCGGCGGCGAGGGCAAGCTCTTTCTTGCGGCACGATGCCGTCTCTGCTGGTGCTC ACTTTCTCCCCGTGCGTACTACTCGGCTGGGCGTTGCTGGCCGGCGGCACCGGTGGCGGT GGCGTTGGCGGCGGCGGCGGTGGCGCGGGCATATGCGGCGGACGCCATGATAGAGATGCG CTGCCGCCACAGAAGATCGAGGTGCTGGTGTTACTGCCCCAGGATGACTCGTACTTGTTT TCACTCACCCGGGTGCGGCCGGCCATCGAGTATGCTCTGCGCATCGTGGACGGCATCGGG ACTGGGATGCGGCTTCTGCCGCCGGGCACTCGCTTCCAGGTGGCTTACGAGGATTCAGAC TGTGGGAACCGTGCGCTCTTCATCTTGGTGGACCGCGTGGCGGCGGCGCAGGGCGCCAAT CCATACCTTATCCTNGCGCCAGTGTGCGAGTATGCATCAGCGCCAGTGGCCCCGCCTGCA TCGCACTGTGACCTGCCCATGCTGTCGGCTGGGGCGCTGGCCGCTGACTTCCANCACAAG GACTCTGAGTACTCGCACCTCACGCGCGTGGCGCCCGCCTACGCCCAGATGGGCGATATG ATGCTCGCCCTGTTCCGCCCCACCACTGTATGCGCGCTGCACTGGGCTACAGCGACGACA TGCTGGAGCCGGATCTGCTACTTCACNCCTCNAGGGGGTCCCACGAGTTCTTCACGAAGG AAGGGTTGGCACACGCCCCTCTACAGTTTCCACGAGACCCAGACTCTGGTCCGGGGAGAC TGGGCGCCATTTCAGCCATGCAAAAAGGGGGGTTCTGGTGGCTAACAAGACCCTTCCGGA CTTTGCTGGTGGGCAAAGCTAGACTGACAAGG >OriGene 3' read for NM_000908 unedited
GTACACTATGNCCGCGGCCGCAATCTATGATCGGTTTTTTTTTTTTTTTTTTACATCAAA AAGGAAATATTTTTGACTTGCTTTTCTTCTGTAAATCCTCCCATCTCACTAATATTTACA ACAATCCAGAGTAGCGTTTATGAGACACTGAAAAAGACAGGGAGGAAATCCTTTTTCAAG ATATGAAGTCAGAACCTGAATGTAGACATCGGACAGAGAAGTCCTCAACCACAAACCTGT CCTCCAGCTCTAGAGAGAGTAAGGCTGTATTTCCAACCTTGAGATTTTTCATTACATTTT CCCCTTTTTGGGTGTTAAATTCTTTCCAAGAATGCTGTACTTGTAAAAATGATTTTATTC TAGCTACAAAACATTTCATTTAAGAAAACCGCATTTTATATCCTTGTGTGAGATGCTCCC AAAAGCCATCAAGATATGGAGACAACAGATTTTAAAAACATAAATCTAATCATATGGGCT TGAAACAGTATGAACATTTAACAGAGTGACACGATATCATTATTATATTTGTTTGTCATG AGATGAAAGGCCTGGNAGCAGATGGTGATTAATCATAATTCCTGAGCTTCTACAGAAATT TTAAAATGAAATTACTAACTGCCTAAAATTATGAATTCTTCAAGAACGCCCCCTTCTGNT NCATTGATGGTCTTTCAACCCGTCTATCTCCTTAAAGGATCTCAGGCAGGAAAAAAAAAA GTGGGGGGGCTTCCTTTTAGCTACTGGAAAAATGGGGTCTGATGGGAATCTTCCCGTAAT TCCCGATGTTTTCCAAAGGCACTTTCCTTTTGCCGGGGTTCGCCCCTTCAAGGGGTATTC TGGATTTTCTTTCCTGAAAAATTGAAAGGCCCTTAGCAAGCCAGCTTCCCATTAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000908 |
| Insert Size | 2750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000908.2, NP_000899.1 |
| RefSeq Size | 2651 bp |
| RefSeq ORF | 1623 bp |
| Locus ID | 4883 |
| UniProt ID | P17342 |
| Domains | ANF_receptor |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation
,Naveen L. Pereira, Dong Lin, Linda Pelleymounter, Irene Moon, Gail Stilling, Bruce W. Eckloff, Eric D. Wieben, Margaret M. Redfield, John C. Burnett, Jr, Vivien C. Yee, and Richard M. Weinshilboum,
Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
,PubMed ID 23493048
[NPR3]
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|
Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide
,Shunbun Kita, Hitoshi Nishizawa, Yosuke Okuno, Masaki Tanaka, Atsutaka Yasui, Morihiro Matsuda, Yukio Yamada, and Iichiro Shimomura,
J. Endocrinol., May 2009; 201: 287 - 295.
[NPR3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219453 | NPR3 (Myc-DDK-tagged)-Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2 |
CNY 6,032.00 |
|
| RC219453L1 | Lenti ORF clone of Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2, Myc-DDK-tagged |
CNY 8,432.00 |
|
| RC219453L2 | Lenti ORF clone of Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC219453L3 | Lenti ORF clone of Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219453L4 | Lenti ORF clone of Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2, mGFP tagged |
CNY 8,432.00 |
|
| RG219453 | NPR3 (tGFP-tagged) - Human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 2 |
CNY 7,632.00 |
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