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MGP (NM_000900) Human Untagged Clone
CAT＃: SC119598
MGP (untagged)-Human matrix Gla protein (MGP), transcript variant 2
CNY 1,800.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GIG36; MGLAP; NTI |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119598 sequence for NM_000900 edited (data generated by NextGen Sequencing)
ATGAAGAGCCTGATCCTTCTTGCCATCCTGGCCGCCTTAGCGGTAGTAACTTTGTGTTAT GAATCACATGAAAGCATGGAATCTTATGAACTTAATCCCTTCATTAACAGGAGAAATGCA AATACCTTCATATCCCCTCAGCAGAGATGGAGAGCTAAAGTCCAAGAGAGGATCCGAGAA CGCTCTAAGCCTGTCCACGAGCTCAATAGGGAAGCCTGTGATGACTACAGACTTTGCGAA CGCTACGCCATGGTTTATGGATACAATGCTGCCTATAATCGCTACTTCAGGAAGCGCCGA GGGACCAAATGA Clone variation with respect to NM_000900.3 >OriGene 5' read for NM_000900 unedited
GCACGAGGATCCCGTAGGAGCCTCTCTCCCTACTGCTGCTACACAAGACCCTGAGACTGA CCTGCAGGACGAAACCATGAAGAGCCTGATCCTTCTTGCCATCCTGGCCGCCTTAGCGGT AGTAACTTTGTGTTATGAATCACATGAAAGCATGGAATCTTATGAACTTAATCCCTTCAT TAACAGGAGAAATGCAAATACCTTCATATCCCCTCAGCAGAGATGGAGAGCTAAAGTCCA AGAGAGGATCCGAGAACGCTCTAAGCCTGTCCACGAGCTCAATAGGGAAGCCTGTGATGA CTACAGACTTTGCGAACGCTACGCCATGGTTTATGGATACAATGCTGCCTATAATCGCTA CTTCAGGAAGCGCCGAGGGACCAAATGAGACTGAGGGAAGAAAAAAAATCTCTTTTTTTC TGGAGGCTGGCACCTGATTTTGTATCCCCCTGTAGCAGCATTACTGAAATACATAGGCTT ATATACAATGCTTCTTTCCTGTATATTCTCTTGTCTGGCTGCACCCCTTTTTCCCGCCCC CAGATTGATAAGTAATGAAAGTGCACTGCAGTGAGGGTCAAAGGAGAGTCAACATATGTG ATTGTTCCATAATAAACTTCTGGTGTGATACTTTCAAAAAAAAAAAAAAAAAACTCGACT CTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGA CCCCTCCCCAGTGCCTCTCCTGGGCCCTGGAGTTGCCACTCCAGTGCCCACC >OriGene 3' read for NM_000900 unedited
TTATCTTGNACGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAAGTATCA CACCAGAAGTTTATTATGGAACAATCACATATGTTGACTCTCCTTTGACCCTCACTGCAG TGCACTTTCATTACTTATCAATCTGGGGGCGGGAAAAAGGGGTGCAGCCAGACAAGAGAA TATACAGGAAAGAAGCATTGTATATAAGCCTATGTATTTCAGTAATGCTGCTACAGGGGG ATACAAAATCAGGTGCCAGCCTCCAGAAAAAAAGAGATTTTTTTTCTTCCCTCAGTCTCA TTTGGTCCCTCGGCGCTTCCTGAAGTAGCGATTATAGGCAGCATTGTATCCATAAACCAT GGCGTAGCGTTCGCAAAGTCTGTAGTCATCACAGGCTTCCCTATTGAGCTCGTGGACAGG CTTAGAGCGTTCTCGGATCCTCTCTTGGACTTTAGCTCTCCATCTCTGCTGAGGGGATAT GAAGGTATTTGCATTTCTCCTGTTAATGAAGGGATTAAGTTCATAAGATTCCATGCTTTC ATGTGATTCATAACACAAAGTTACTACCGCTAAGGCGGCCAGGATGGCAAGAAGGATCAG GCTCTTCATGGTTTCGTCCTGCAGGTCAGTCTCAGGGTCTTGTGTAGCAGCAGTAGGGAG AGAGGCTCCTACGGGATCCTCGTGCCGAATTCGCCGCCGNCCTATAGTGAGTCGTATTAC AAAATTCTGACGGTTCCACTAACGAGCTCTGGCTATATAGACCTCCCACCGTACACGCCT ACCGCCCATTTGCGTCAACGGGGGCGGGGTATTACGACATTTTGGAAAGTCCCGTTGATT TTGTGCCCAAACAACTCCAATTGACGGTCATGGGGGGGAGACTTGGAAACCCCGGGAGTC AAACCGCTATCCGGCCCATGGGGTACTGCCAAAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000900 |
| Insert Size | 700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000900.2, NP_000891.2 |
| RefSeq Size | 661 bp |
| RefSeq ORF | 312 bp |
| Locus ID | 4256 |
| UniProt ID | P08493 |
| Domains | GLA |
| Protein Families | Secreted Protein |
| Gene Summary | This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016] Transcript Variant: This variant (2) represents the shorter transcript and encodes the shorter isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210666 | MGP (Myc-DDK-tagged)-Human matrix Gla protein (MGP), transcript variant 2 |
CNY 1,800.00 |
|
| RC210666L1 | Lenti ORF clone of Human matrix Gla protein (MGP), transcript variant 2, Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC210666L2 | Lenti ORF clone of Human matrix Gla protein (MGP), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC210666L3 | Lenti ORF clone of Human matrix Gla protein (MGP), transcript variant 2, Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC210666L4 | Lenti ORF clone of Human matrix Gla protein (MGP), transcript variant 2, mGFP tagged |
CNY 4,200.00 |
|
| RG210666 | MGP (tGFP-tagged) - Human matrix Gla protein (MGP), transcript variant 2 |
CNY 3,400.00 |
