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Leukotriene A4 hydrolase (LTA4H) (NM_000895) Human Untagged Clone
CAT＃: SC119594
LTA4H (untagged)-Human leukotriene A4 hydrolase (LTA4H)
CNY 4,560.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119594 sequence for NM_000895 edited (data generated by NextGen Sequencing)
ATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCCGGCTTCCGTCTGCCGGACCAAG CACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCT CTCACGGTCCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTT ACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAA ATTGTTATAGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACT CCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAG GTGTCTGTCCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCT GACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTG GTGTGGTCTGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCT ATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACT CCTACTCTACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCAT AGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACAT TTTAATGCTCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACA CATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGA CCAGAGATTTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATA ACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAAT TATGATATGACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGCCAAA GAAGATGATTTAAATTCATTCAATGCCACAGACCTGAAGGATCTCTCTTCTCATCAATTG AATGAGTTTTTAGCACAGACGCTCCAGAGGGCACCTCTTCCATTGGGGCACATAAAGCGA ATGCAAGAGGTGTACAACTTCAATGCCATTAACAATTCTGAAATACGATTCAGATGGCTG CGGCTCTGCATTCAATCCAAGTGGGAGGACGCAATTCCTTTGGCGCTAAAGATGGCAACT GAACAAGGAAGAATGAAGTTTACCCGGCCCTTATTCAAGGATCTTGCTGCCTTTGACAAA TCCCATGATCAAGCTGTCCGAACCTACCAAGAGCACAAAGCAAGCATGCATCCCGTGACT GCAATGCTGGTGGGGAAAGACTTAAAAGTGGATTAA Clone variation with respect to NM_000895.1 >OriGene 5' read for NM_000895 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTGGGCTGTAGGTC GCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCT CTCCGGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTC GCCGGACGCTGACCGGGACTGCTGCTCTCACGGTCCAGTCTCAGGAGGACAATCTGCGCA GCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAG TCAAATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTC CTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCTCCAA AATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATC TCTTTAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTT CTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTTATGA GTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGANAATATACAAAT TCATCCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAA GCAGGCAAATTGGCCCAAGAACTNTGGGTGTGGTCTGAGAAAGAGCANGTGGAAAAGTCT GCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAAAGCANAAGATCTGGNGAGACCGT ATGTATGGGGACAGTATGACCTATTGGTCCTGCCACATCCTTCCCTATGTNGCATGGAGA TTCTG >OriGene 3' read for NM_000895 unedited
CTCAATTCTATTTTTTTTAAAATCACCAACAAAACATAAAAAGCCAACTAAAAAGACAGT TTTAATTGTGAGCTGAAGTTTTATATTTCTTTACGAATTCCATTTAAAAAAGAGAAATCT CTAAAATCATCAATACGCAGGTCTTTAATCCACTTTTAAGTCTTTCCCCACCAGCATTGC AGTCACGGGATGCATGCTTGCTTTGTGCTCTTGGTAGGTTCGGACAGCTTGATCATGGGA TTTGTCAAAGGCAGCAAGATCCTTGAATAAGGGCCGGGTAAACTTCATTCTTCCTTGTTC AGTTGCCATCTTTAGCGCCAAAGGAATTGCGTCCTCCCACTTGGATTGAATGCAGAGCCG CAGCCATCTGAATCGTATTTCAGAATTGTTAATGGCATTGAAGCCGTACACCTCTTGCAT TCGCTTTATGTGCCCCAATGGAAGACGTGCCCTCTGGAGCGCCCGCGCTAAAAACTCATT CACTTGATGAGAAAATAGAACCTTCAAGTCTCGCGGCATTGCATGAATCTAACACATCTC TTTCTGGCGAGACATCCATCTTTCGCTCAAGGGCCTAGTCGCCTCTGTCATAGCCATCTT ATTATCTCGGCCTTACTGTGTCGCACTCCACGGACACGTAGAGTCATGTCCTTCAATCCC CCCGCATGTGAACATGCACCTCATCCCTACACATGGACCCCGGACATCTCCCCGTCACTA ATCATTTGCGTGCATCGGGATGCCCTCCTACCACACCTCTAATAATACACTGAACACCTT TGTCCTCCTCTCTGTTTCACCGGATTCAGTAGCTACGACCGTTTTACGTGTCCTGCTTAC CGCTTCCGTCGCGCCTTTCCGCCCGACCATTCATTCTTTTCCACTCATTATCTCCCCCCG CCTCGCTTAACNTCGNNATCATCCATCCCAATTACCCCACGCCTCGCATTGGCCAAACAT CCACCACATGCGCCCCTCCCCACTATGCCACCTCATACTCCCTGTAGCCACCATATCGCC T |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000895 |
| Insert Size | 2230 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000895.1, NP_000886.1 |
| RefSeq Size | 2060 bp |
| RefSeq ORF | 1836 bp |
| Locus ID | 4048 |
| UniProt ID | P09960 |
| Domains | Peptidase_M1 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Arachidonic acid metabolism, Metabolic pathways |
| Gene Summary | The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
,Vincent Sandanayaka,Jasbir Singh, Lei Zhao, Mark E. Gurney,
United States Patent
[LTA4H]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207617 | LTA4H (Myc-DDK-tagged)-Human leukotriene A4 hydrolase (LTA4H) |
CNY 4,552.00 |
|
| RC207617L3 | Lenti ORF clone of Human leukotriene A4 hydrolase (LTA4H), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207617L4 | Lenti ORF clone of Human leukotriene A4 hydrolase (LTA4H), mGFP tagged |
CNY 5,890.00 |
|
| RG207617 | LTA4H (tGFP-tagged) - Human leukotriene A4 hydrolase (LTA4H) |
CNY 6,152.00 |
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