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Integrin alpha 4 (ITGA4) (NM_000885) Human Untagged Clone
CAT＃: SC119587
ITGA4 (untagged)-Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4)
CNY 7,192.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD49D; IA4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000885 edited
GAATTCGGCACGAGGCCTTCCTTTAGCCCGCTGGCGCCGGACACGCTGCGCCTCATCTCT TGGGGCGTTCTTCCCCGTTGGCCAACCGTCGCATCCCGTGCAACTTTGGGGTAGTGGCCG TTTAGTGTTGAATGTTCCCCACCGAGAGCGCATGGCTTGGGAAGCGAGGCGCGAACCCGG CCCCCGAAGGGCCGCCGTCCGGGAGACGGTGATGCTGTTGCTGTGCCTGGGGGTCCCGAC CGGCCGCCCCTACAACGTGGACACTGAGAGCGCGCTGCTTTACCAGGGCCCCCACAACAC GCTGTTCGGCTACTCGGTCGTGCTGCACAGCCACGGGGCGAACCGATGGCTCCTAGTGGG TGCGCCCACTGCCAACTGGCTCGCCAACGCTTCAGTGATCAATCCCGGGGCGATTTACAG ATGCAGGATCGGAAAGAATCCCGGCCAGACGTGCGAACAGCTCCAGCTGGGTAGCCCTAA TGGAGAACCTTGTGGAAAGACTTGTTTGGAAGAGAGAGACAATCAGTGGTTGGGGGTCAC ACTTTCCAGACAGCCAGGAGAAAATGGATCCATCGTGACTTGTGGGCATAGATGGAAAAA TATATTTTACATAAAGAATGAAAATAAGCTCCCCACTGGTGGTTGCTATGGAGTGCCCCC TGATTTACGAACAGAACTGAGTAAAAGAATAGCTCCGTGTTATCAAGATTATGTGAAAAA ATTTGGAGAAAATTTTGCATCATGTCAAGCTGGAATATCCAGTTTTTACACAAAGGATTT AATTGTGATGGGGGCCCCAGGATCATCTTACTGGACTGGCTCTCTTTTTGTCTACAATAT AACTACAAATAAATACAAGGCTTTTTTAGACAAACAAAATCAAGTAAAATTTGGAAGTTA TTTAGGATATTCAGTCGGAGCTGGTCATTTTCGGAGCCAGCATACTACCGAAGTAGTCGG AGGAGCTCCTCAACATGAGCAGATTGGTAAGGCATATATATTCAGCATTGATGAAAAAGA ACTAAATATCTTACATGAAATGAAAGGTAAAAAGCTTGGATCGTACTTTGGAGCTTCTGT CTGTGCTGTGGACCTCAATGCAGATGGCTTCTCAGATCTGCTCGTGGGAGCACCCATGCA GAGCACCATCAGAGAGGAAGGAAGAGTGTTTGTGTACATCAACTCTGGCTCGGGAGCAGT AATGAATGCAATGGAAACAAACCTCGTTGGAAGTGACAAATATGCTGCAAGATTTGGGGA ATCTATAGTTAATCTTGGCGACATTGACAATGATGGCTTTGAAGATGTTGCTATCGGAGC TCCACAAGAAGATGACTTGCAAGGTGCTATTTATATTTACAATGGCCGTGCAGATGGGAT CTCGTCAACCTTCTCACAGAGAATTGAAGGACTTCAGATCAGCAAATCGTTAAGTATGTT TGGACAGTCTATATCAGGACAAATTGATGCAGATAATAATGGCTATGTAGATGTAGCAGT TGGTGCTTTTCGGTCTGATTCTGCTGTCTTGCTAAGGACAAGACCTGTAGTAATTGTTGA CGCTTCTTTAAGCCACCCTGAGTCAGTAAATAGAACGAAATTTGACTGTGTTGAAAATGG ATGGCCTTCTGTGTGCATAGATCTAACACTTTGTTTCTCATATAAGGGCAAGGAAGTTCC AGGTTACATTGTTTTGTTTTATAACATGAGTTTGGATGTGAACAGAAAGGCAGAGTCTCC ACCAAGATTCTATTTCTCTTCTAATGGAACTTCTGACGTGATTACAGGAAGCATACAGGT GTCCAGCAGAGAAGCTAACTGTAGAACACATCAAGCATTTATGCGGAAAGATGTGCGGGA CATCCTCACCCCAATTCAGATTGAAGCTGCTTACCACCTTGGTCCTCATGTCATCAGTAA ACGAAGTACAGAGGAATTCCCACCACTTCAGCCAATTCTTCAGCAGAAGAAAGAAAAAGA CATAATGAAAAAAACAATAAACTTTGCAAGGTTTTGTGCCCATGAAAATTGTTCTGCTGA TTTACAGGTTTCTGCAAAGATTGGGTTTTTGAAGCCCCATGAAAATAAAACATATCTTGC TGTTGGGAGTATGAAGACATTGATGTTGAATGTGTCCTTGTTTAATGCTGGAGATGATGC ATATGAAACGACTCTACATGTCAAACTACCCGTGGGTCTTTATTTCATTAAGATTTTAGA GCTGGAAGAGAAGCAAATAAACTGTGAAGTCACAGATAACTCTGGCGTGGTACAACTTGA CTGCAGTATTGGCTATATATATGTAGATCATCTCTCAAGGATAGATATTAGCTTTCTCCT GGATGTGAGCTCACTCAGCAGAGCGGAAGAGGACCTCAGTATCACAGTGCATGCTACCTG TGAAAATGAAGAGGAAATGGACAATCTAAAGCACAGCAGAGTGACTGTAGCAATACCTTT AAAATATGAGGTTAAGCTGACTGTTCATGGGTTTGTAAACCCAACTTCATTTGTGTATGG ATCAAATGATGAAAATGAGCCTGAAACGTGCATGGTGGAGAAAATGAACTTAACTTTCCA TGTTATCAACACTGGCAATAGTATGGCTCCCAATGTTAGTGTGGAAATAATGGTACCAAA TTCTTTTAGCCCCCAAACTGATAAGCTGTTCAACATTTTGGATGTCCAGACTACTACTGG AGAATGCCACTTTGAAAATTATCAAAGAGTGTGTGCATTAGAGCAGCAAAAGAGTGCAAT GCAGACCTTGAAAGGCATAGTCCAGTTCTTGTCCAAGACTGATAAGAGGCTATTGTACTG CATAAAAGCTGATCCACATTGTTTAAATTTCTTGTGTAATTTTGGGAAAATGGAAAGTGG AAAAGAAGCCAGTGTTCATATCCAACTGGAAGGCCGGCCATCCATTTTAGAAATGGATGA GACTTCAGCACTCAAGTTTGAAATAAGAGCAACAGGTTTTCCAGAGCCAAATCCAAGAGT AATTGAACTAAACAAGGATGAGAATGTTGCGCATGTTCTACTGGAAGGACTACATCATCA AAGACCCAAACGTTATTTCACCATAGTGATTATTTCAAGTAGCTTGCTACTTGGACTTAT TGTACTTCTGTTGATCTCATATGTTATGTGGAAGGCTGGCTTCTTTAAAAGACAATACAA ATCTATCCTACAAGAAGAAAACAGAAGAGACAGTTGGAGTTATATCAACAGTAAAAGCAA TGATGATTAAGGACTTCTTTCAAATTGAGAGAATGGAAAACAGACTCAGGTTGTAGTAAA GAAATTTAAAAGACACTGTTTACAAGAAAAAATGAATTTTGTTTGGACTTCTTTTACTCA TGATCTTGTGACATATTATGTCTTCATGCAAGGGGAAAATCTCAGCAATGATTACTCTTT GAGATAGAAGAACTGCAAAGGTAATAATACAGCCAAAGATAATCTCTCAGCTTTTAAATG GGTAGAGAAACACTAAAGCATTCAATTTATTCAAGAAAAGTAAGCCCTTGAAGATATCTT GAAATGAAAGTATAACTGAGTTAAATTATACTGGAGAAGTCTTAGACTTGAAATACTACT TACCATATGTGCTTGCCTCAGTAAAATGAACCCCACTGGGTGGGCAGAGGTTCATTTCAA ATACATCTTTGATACTTGTTCAAAATATGTTCTTTAAAAATATAATTTTTTAGAGAGCTG TTCCCAAATTTTCTAACGAGTGGACCATTATCACTTTAAAGCCCTTTATTTATAATACAT TTCCTACGGGCTGTGTTCCAACAACCATTTTTTTTCAGCAGACTATGAATATTATAGTAT TATAGGCCAAACTGGCAAACTTCAGACTGAACATGTACACTGGTTTGAGCTTAGTGAAAT GACTTCTGGATAATTATTTTTTTATAATTATGGATTTCACCATCTTTCTTTCTGTATATA TACATGTGTTTTTATGTAGGTATATATTTACCATTCTTCCTATCTATTCTTCCTATAACA CACCTTTATCAAGCATACCCAGGAGTAATCTTCAAATCTTTTGTTATATTCTGAAACAAA AGATTGTGAGTGTTGCACTTTACCTGATACATGCTGATTTAGAAAATACAGAAACCATAC CTCACTAATAACTTTAAAATCAAAGCTGTGCAAAGACTAGGGGGCCTATACTTCATATGT ATTATGTACTATGTAAAATATTGACTATCACACAACTATTTCCTTGGATGTAATTCTTTG TTACCCTTTACAAGTATAAGTGTTACCTTACATGGAAACGAAGAAACAAAATTCATAAAT TTAAATTCATAAATTTAGCTGAAAGATACTGATTCAATTTGTATACAGTGAATATAAATG AGACGACAGCAAAATTTTCATGAAATGTAAAATATTTTTATAGTTTGTTCATACTATATG AGGTTCTATTTTAAATGACTTTCTGGATTTTAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_000885 unedited
NGGGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCTTCCT TTAGCCCGCTGGCGCCGGNCACGCTGCGCCTCATCTCTTGGGGCGTTCTTCCCCGTTGGC CAACCGTCGCATCCCGTGCAACTTTGGGGTAGTGGCCGTTTAGTGTTGAATGTTCCCCAC CGAGAGCGCATGGCTTGGGAAGCGAGGCGCGAACCCGGCCCCCGAAGGGCCGCCGTCCGG GAGACGGTGATGCTGTTGCTGTGCCTGGGGGTCCCGACCGGCCGCCCCTACAACGTGGAC ACTGAGAGCGCGCTGCTTTACCAGGGCCCCCACAACACGCTGTTCGGCTACTCGGTCGTG CTGCACAGCCACGGGGCGAACCGATGGCTCCTAGTGGGTGCGCCCACTGCCAACTGGCTC GCCAACGCTTCAGTGATCAATCCCGGGGCGATTTACAGATGCAGGATCGGAAAGAATCCC GGCCAGACGTGCGAACAGCTCCAGCTGGGTAGCCCTAATGGAGAACCTTGTGGAAAGACT TGTTTGGAAGAGAGAGACAATCAGTGGTTGGGGGTCACACTTTCCAGACAGCCAGGAGAA AATGGATCCATCGTGACTTGTGGGCATAGATGGAAAAATATATTTTACATAAAGAATGAA AATAAGCTCCCCACTGGTGGTTGCTATGGAGTGCCCCCTGATTTACGAACAGAACTGAGT AAAAGAATAGCTCCGTGTTATCAAGAATATGTGAAAAAAATTTGGAGAAAATTNTGCATC ATGTCAAGCTGGAATATCCAGTTTTTACACAAAGGATTTAATTGTGATGGGGGCCCCAGG ATCATCTTACTGGACTGGCTCTCTTTTGTCTACAATATACTACAAATAAATACAAGCCTT TT >OriGene 3' read for NM_000885 unedited
ATGAACTGCGGCCGCAATCTAGAGTCGAGTTACTTTTTTTTTTTTTTTTTAACTATCCAG AAAGTCTACTTAAAATAGAACCTCATATAGTATGAACAAACTATAAACTTATTCTAACTT TATATGAAAATTTTGCTGTCTTCCTAATTATATTACTTGTATACAAATTGAATCAGTATC TTTCAGCTAAATTTATGAATTTAAATTTATGAATTTTGTTTCTTCGTTTCCATGTAGCGT ATCACTTATTCTTGCAAAGGGACTACATAATATTACTTATAAGGAAATAGTTGATTGATA CTCATATATTTCTCATACATCATAATATATAATAAGCATAGGCCCCTTATTCTTTAGTAC ACTTTTGATTATATAGTTATTACTGAATTATCGTTTCTGTATTATCTAAAACAGCATGTA ACTACCAAAGTGCAACACATACAATCTTTTGTTTCAGAATATAACAAAAGATTTGAAGAT TACTCCTGGGATATTCTTGATCAAATTGTGTTATAGGTAGAATACTATAGGAAAAATATC ACATATCTACCTACATATAAACACCTGTATATATACAGAATGAAAGATGGTGAAATCACT AATTATTATCTAATAATTATCCATAAGTCATTTNACTAAGCTCAAACCAGTGTACATGTT CAATCTGAAGTTTGCCAGATTGGCCTATAATACTATATAATTCATAGCCTGATGANAAAA AATGGATGCTGGNACACAGCCCGTAGGAAATTATTATAAAACTAGGCTTTAAGTGATAAT GGTCACTCGTTATAAATTTGTGACAGCATTTTAAATATATATTTTTAAGAAATTCTTCCT CACGACNAAATAGAACTTGAAGAAACNNNGNNANCAGGGGATTAATTTANTGNNGGNGNN CTNGGNNNGNNNNNNNNAGNNNANNNNTNNNNNNAATTNANATNNATATTATTATCTGAA TTTNAGGGCCTACTTCTGACTAAAGAGCTTAATTTTTATAATTACAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000885 |
| Insert Size | 4760 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000885.4, NP_000876.3 |
| RefSeq Size | 6082 bp |
| RefSeq ORF | 3099 bp |
| Locus ID | 3676 |
| UniProt ID | P13612 |
| Domains | FG-GAP |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
| Gene Summary | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Envelope Glycoprotein Binding to the a4ß7 Integrin Complex is not a General Property of Most HIV-1 Variants
,Perez, LG;Chen, H;Liao, HX;Montefiori, DC;,
J. Virol. July 2014
,PubMed ID 25008916
[ITGA4]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214408 | ITGA4 (Myc-DDK-tagged)-Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4) |
CNY 7,184.00 |
|
| RC214408L1 | Lenti ORF clone of Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), Myc-DDK-tagged |
CNY 9,584.00 |
|
| RC214408L2 | Lenti ORF clone of Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), mGFP tagged |
CNY 12,160.00 |
|
| RC214408L3 | Lenti ORF clone of Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), Myc-DDK-tagged |
CNY 9,584.00 |
|
| RC214408L4 | Lenti ORF clone of Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), mGFP tagged |
CNY 9,584.00 |
|
| RG214408 | ITGA4 (tGFP-tagged) - Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4) |
CNY 8,784.00 |
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