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CD13 (ANPEP) (NM_001150) Human Untagged Clone
CAT＃: SC119422
ANPEP (untagged)-Human alanyl (membrane) aminopeptidase (ANPEP)
CNY 10,632.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APN; CD13; GP150; LAP1; P150; PEPN |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001150 edited
GAATTCGGCACGAGCCAGTGCTGGAGGGGCAGGGACGGCGGCGGCGCAGCTCGGAACCCG CCAGGGTCCAGGGTCCAGGTTCCAGCGCCCGGCGGCCCAGCTCTCAAGCAGATCAATGCA ATGCCACCTGGCCGCTTGCTTTGCCCACTGGGCCTACAGCCGGAAGCCTGCCCTTCAGCC CTCGGGCCTGATCCCAGGCCGCCTGCAGCCTGTAACCAGACACTGTTTGCTTCCAGCAGG CACCCCCCGAGCCCAGCTCCACACACCGTTCCTGGATCTCCTCTCCCCAGGCGGAGCGTG CCCCTGCCCAGTCCAGCGACCTTCGCCTGTTGGAGCCCTGGTTAATTTTTGCCCAGTCTG CCTGTTGTGGGGCTCCTCCCCTTTGGGGATATAAGCCCGGCCTGGGGCTGCTCCGTTCTC TGCCTGGCCTGAGGCTCCCTGAGCCGCCTCCCCACCATCACCATGGCCAAGGGCTTCTAT ATTTCCAAGTCCCTGGGCATCCTGGGGATCCTCCTGGGCGTGGCAGCCGTGTGCACAATC ATCGCACTGTCAGTGGTGTACTCCCAGGAGAAGAACAAGAACGCCAACAGCTCCCCCGTG GCCTCCACCACCCCGTCCGCCTCAGCCACCACCAACCCCGCCTCGGCCACCACCTTGGAC CAAAGTAAAGCGTGGAATCGTTACCGCCTCCCCAACACGCTGAAACCCGATTCCTACCAG GTGACGCTGAGACCGTACCTCACCCCCAATGACAGGGGCCTGTACGTTTTTAAGGGCTCC AGCACCGTCCGTTTCACCTGCAAGGAGGCCACTGATGTCATCATCATCCACAGCAAGAAG CTCAACTACACCCTCAGCCAGGGGCACAGGGTGGTCCTGCGTGGTGTGGGAGGCTCCCAG CCCCCCGACATTGACAAGACTGAGCTGGTGGAGCCCACCGAGTACCTGGTGGTGCACCTC AAGGGCTCCCTGGTGAAGGACAGCCAGTATGAGATGGACAGCGAGTTCGAGGGGGAGTTG GCAGATGACCTGGCGGGCTTCTACCGCAGCGAGTACATGGAGGGCAATGTCAGAAAGGTG GTGGCCACTACACAGATGCAGGCTGCAGATGCCCGGAAGTCCTTCCCATGCTTCGATGAG CCGGCCATGAAGGCCGAGTTCAACATCACGCTTATCCACCCCAAGGACCTGACAGCCCTG TCCAACATGCTTCCCAAAGGTCCCAGCACCCCACTTCCAGAAGACCCCAACTGGAATGTC ACTGAGTTCCACACCACGCCCAAGATGTCCACGTACTTGCTGGCCTTCATTGTCAGTGAG TTCGACTACGTGGAGAAGCAGGCATCCAATGGTGTCTTGATCCGGATCTGGGCCCGGCCC AGTGCCATTGCGGTGGGCCACGGCGATTATGCCCTTAACGTGACAGGCCCCATCCTTAAC TTCTTTGCTGGTCATTATGACACACCCTACCCACTCCCAAAATCAGACCAGATTGGCCTG CCAGACTTCAACGCCGGCGCCATGGAGAACTGGGGACTGGTGACCTACCGGGAGAACTCC CTGCTGTTCGACCCCCTGTCCTCCTCCAGCAGCAACAAGGAGCGGGTGGTCACTGTGATT GCTCATGAGCTGGCCCACCAGTGGTTCGGGAACCTGGTGACCATAGAGTGGTGGAATGAC CTGTGGCTGAACGAGGGCTTCGCCTCCTACGTGGAGTACCTGGGTGCTGACTATGCGGAG CCCACCTGGAACTTGAAAGACCTCATGGTGCTGAATGATGTGTACCGCGTGATGGCAGTG GATGCACTGGCCTCCTCCCACCCGCTGTCCACACCCGCCTCGGAGATCAACACGCCGGCC CAGATCAGTGAGCTGTTTGACGCCATCTCCTACAGCAAGGGCGCCTCAGTCCTCAGGATG CTCTCCAGCTTCCTGTCCGAGGACGTATTCAAGCAGGGCCTGGCGTCCTACCTCCACACC TTTGCCTACCAGAACACCATCTACCTGAACCTGTGGGACCACCTGCAGGAGGCTGTGAAC AACCGGTCCATCCAACTCCCCACCACCGTGCGGGACATCATGAACCGCTGGACCCTGCAG ATGGGCTTCCCGGTCATCACGGTGGATACCAGCACGGGGACCCTTTCCCAGGAGCACTTC CTCCTTGACCCCGATTCCAATGTTACCCGCCCCTCAGAATTCAACTACGTGTGGATTGTG CCCATCACATCCATCAGAGATGGCAGACAGCAGCAGGACTACTGGCTGATAGATGTAAGA GCCCAGAACGATCTCTTCAGCACATCAGGCAATGAGTGGGTCCTGCTGAACCTCAATGTG ACGGGCTATTACCGGGTGAACTACGACGAAGAGAACTGGAGGAAGATTCAGACTCAGCTG CAGAGAGACCACTCGGCCATCCCTGTCATCAATCGGGCACAGATCATTAATGACGCCTTC AACCTGGCCAGTGCCCATAAGGTCCCTGTCACTCTGGCGCTGAACAACACCCTCTTCCTG ATTGAAGAGAGACAGTACATGCCCTGGGAGGCCGCCCTGAGCAGCCTGAGCTACTTCAAG CTCATGTTTGACCGCTCCGAGGTCTATGGCCCCATGAAGAACTACCTGAAGAAGCAGGTC ACACCCCTCTTCATTCACTTCAGAAATAATACCAACAACTGGAGGGAGATCCCAGAAAAC CTGATGGACCAGTACAGCGAGGTTAATGCCATCAGCACCGCCTGCTCCAACGGAGTTCCA GAGTGTGAGGAGATGGTCTCTGGCCTTTTCAAGCAGTGGATGGAGAACCCCAATAATAAC CCGATCCACCCCAACCTGCGGTCCACCGTCTACTGCAACGCTATCGCCCAGGGCGGGGAG GAGGAGTGGGACTTCGCCTGGGAGCAGTTCCGAAATGCCACACTGGTCAATGAGGCTGAC AAGCTCCGGGCAGCCCTGGCCTGCAGCAAAGAGTTGTGGATCCTGAACAGGTACCTGAGC TACACCCTGAACCCGGACTTAATCCGGAAGCAGGACGCCACCTCTACCATCATCAGCATT ACCAACAACGTCATTGGGCAAGGTCTGGTCTGGGACTTTGTCCAGAGCAACTGGAAGAAG CTTTTTAACGATTATGGTGGTGGCTCGTTCTCCTTCTCCAACCTCATCCAGGCAGTGACA CGACGATTCTCCACCGAGTATGAGCTGCAGCAGCTGGAGCAGTTCAAGAAGGACAACGAG GAAACAGGCTTCGGCTCAGGCACCCGGGCCCTGGAGCAAGCCCTGGAGAAGACGAAAGCC AACATCAAGTGGGTGAAGGAGAACAAGGAGGTGGTGCTCCAGTGGTTCACAGAAAACAGC AAATAGTCCCCAGCCCTTGAAGTCACCCGGCCCCGATGCAAGGTGCCCACATGTGTCCAT CCCAGCGGCTGGTGCAGGGCCTCCATTCCTGGAGCCCGAGGCACCAGTGTCCTCCCCTCA AGGACAAAGTCTCCAGCCCACGTTCTCTCTGCCTGTGAGCCAGTCTAGTTCCTGATGACC CAGGCTGCCTGAGCACCTCCCAGCCCCTGCCCCTCATGCCAACCCCGCCCTAGGCCTGGC ATGGCACCTGTCGCCCAGTGCCCTGGGGCTGATCTCAGGGAAGCCCAGCTCCAGGGCCAG ATGAGCAGAAGCTCTCGATGGACAATGAACGGCCTTGCTGGGGGCCGCCCTGTACCCTCT TTCACCTTTCCCTAAAGACCCTAAATCTGAGGAATCAACAGGGCAGCAGATCTGTATATT TTTTTCTAAGAGAAAATGTAAATAAAGGATTTCTAGATGAAAAAAAAAAAAAAAAAAAAC TCGAC >OriGene 5' read for NM_001150 unedited
GGGCGGGGGGNANAANACANTCNCCCCCCCGGGTTCAAAATTGTATACGATCATATAGGG CGGCCGCGAATCGGCACGAGCCAGTGCTGGAGGGGCAGGGACGGCGGCGGCGCAGCTCGG AACCCGCCAGGGTCCAGGGTCCAGGTTCCAGCGCCCGGCGGCCCAGCTCTCAAGCAGATC AATGCAATGCCACCTGGCCGCTTGCTTTGCCCACTGGGCCTACAGCCGGAAGCCTGCCCT TCAGCCCTCGGGCCTGATCCCAGGCCGCCTGCAGCCTGTAACCAGACACTGTTTGCTTCC AGCAGGCACCCCCCGAGCCCAGCTCCACACACCGTTCCTGGATCTCCTCTCCCCAGGCGG AGCGTGCCCCTGCCCAGTCCAGCGACCTTCGCCTGTTGGAGCCCTGGTTAATTTTTGCCC AGTCTGCCTGTTGTGGGGCTCCTCCCCTTTGGGGATATAAGCCCGGCCTGGGGCTGCTCC GTTCTCTGCCTGGCCTGAGGCTCCCTGAGCCGCCTCCCCACCATCACCATGGCCAAGGGC TTCTATATTTCCAAGTCCCTGGGCATCCTGGGGATCCTCCTGGGCGTGGCAGCCGTGTGC ACAATCATCGCACTGTCAGTGGTGTACTCCCAGGAGAAGAACAAGAACGCCAACAGCTCC CCCGTGGCCTCCACCACCCCGTCCGCCTCAGCCACCACCAACCCCGCCTCGGCCACCACC TTGGNACCAAAGTAAGCGTGGAATCGTTACCGCCTCCCCACACGCTGAAACCCGATTCCT ACCAGGTGACGCTGAGACCGTACCTCACCCCCCATGACAGGGGCCTGTACGTTNNTAAGG GCTNCAGCACCGTCCGTTTCACCTGCAGGGAGGCCACTGATGTCATCATCATCCCACAGC AGAAGCTCAACTACACCCTCANCAGGGGCACAGGGTGGTTCTGCGTGGA >OriGene 3' read for NM_001150 unedited
CGGGGCCNNNNNNNCCTTCNNNNANNAAGATTTGAACCCGGCCGCATTCTANGATCGGTT TTTTTTTTTTTTTTTTTTCATCAAAAAACCTTTATTTACATTTTCTCTTAGAAAAAAAAT ACAGATCTGCTGCCCTGTTGATTCCTCAAATTTAGGGTCTTTAGGGAAAGGTGAAAGAGG GTACAGGGCGGCCCCCAGCAAGGCCGTTCATTGTCCATCGAGAGCTTCTGCTCATCTGGC CCTGGAGCTGGGCTTCCCTGAGATCAGCCCCAGGGCACTGGGCGACAGGTGCCATGCCAG GCCTAGGGCGGGGTTGGCATGAGGGGCAGGGGCTGGGAGGTGCTCAGGCAGCCTGGGTCA TCAGGAACTAGACTGGCTCACAGGCAGAGAGAACGTGGGCTGGAGACTTTGTCCTTGAGG GGAGGACACTGGTGCCTCGGGCTCCAGGAATGGAGGCCCTGCACCAGCCGCTGGGATGGA CACATGTGGGCACCTTGCATCGGGGCCGGGTGACTTCAAGGGCTGGGGACTATTTGCTGT TTTCTGTGAACCACTGGAGCACCACCTCCTTGTTCTCCTTCACCCACTTGATGTTGGCTT TCGTCTTCTCCAGGGCTTGCTCCAGGGCCCGGGTGCCTGAGCCGAAGCCTGTTTCCTCGT TGNCCTTCTTGAACTGCTCCAGCTGCTGCAGCTCATACCTCGTGGAGAATCGTCGTGTCA CTGCCTGAATGAGGNTGGAGAAGGAGAACGAGCCACCACCATATCGTTAAAAGCTTCTTN CAGTTGCTCTGGNACAAGTCCNAGACCAGACTTGCCCATGACGNTGNTNGTAATGCTGAT GATGGGAAAGGTGGCGTCCTGCTTCCCGGATTAGTCCGGNTNCNGGGTGTAGCTCAGGTA CCCTGTCAGGATCCACCACTCTTTGCTGCAGCCAGGGCTTGCCNGGACTTGCCACCTCAT GAACACTGTGGCATTTCGGACTGCTCAAGGCGAATCCCACTCTCCTCCCGCCTGGGCGAT G |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001150 |
| Insert Size | 3750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001150.1, NP_001141.1 |
| RefSeq Size | 3494 bp |
| RefSeq ORF | 2904 bp |
| Locus ID | 290 |
| UniProt ID | P15144 |
| Domains | Peptidase_M1 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane |
| Protein Pathways | Glutathione metabolism, Hematopoietic cell lineage, Metabolic pathways, Renin-angiotensin system |
| Gene Summary | Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208950 | ANPEP (Myc-DDK-tagged)-Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 10,624.00 |
|
| RC208950L1 | Lenti-ORF clone of ANPEP (Myc-DDK-tagged)-Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 13,024.00 |
|
| RC208950L2 | Lenti-ORF clone of ANPEP (mGFP-tagged)-Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 13,024.00 |
|
| RC208950L3 | Lenti-ORF clone of ANPEP (Myc-DDK-tagged)-Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 13,024.00 |
|
| RC208950L4 | Lenti-ORF clone of ANPEP (mGFP-tagged)-Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 5,890.00 |
|
| RG208950 | ANPEP (tGFP-tagged) - Human alanyl (membrane) aminopeptidase (ANPEP) |
CNY 12,224.00 |
