FLAP (ALOX5AP) (NM_001629) Human Untagged Clone
CAT#: SC119165
ALOX5AP (untagged)-Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | FLAP |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119165 sequence for NM_001629 edited (data generated by NextGen Sequencing)
ATGGATCAAGAAACTGTAGGCAATGTTGTCCTGTTGGCCATCGTCACCCTCATCAGCGTG GTCCAGAATGGATTCTTTGCCCATAAAGTGGAGCACGAAAGCAGGACCCAGAATGGGAGG AGCTTCCAGAGGACCGGAACACTTGCCTTTGAGCGGGTCTACACTGCCAACCAGAACTGT GTAGATGCGTACCCCACTTTCCTCGCTGTGCTCTGGTCTGCGGGGCTACTTTGCAGCCAA GTTCCTGCTGCGTTTGCTGGACTGATGTACTTGTTTGTGAGGCAAAAGTACTTTGTCGGT TACCTAGGAGAGAGAACGCAGAGCACCCCTGGCTACATATTTGGGAAACGCATCATACTC TTCCTGTTCCTCATGTCCGTTGCTGGCATATTCAACTATTACCTCATCTTCTTTTTCGGA AGTGACTTTGAAAACTACATAAAGACGATCTCCACCACCATCTCCCCTCTACTTCTCATT CCCTAA Clone variation with respect to NM_001629.3 >OriGene 5' read for NM_001629 unedited
TCACAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACCAGCAAACATGGATCA AGAAACTGTAGGCAATGTTGTCCTGTTGGCCATCGTCACCCTCATCAGCGTGGTCCAGAA TGGATTCTTTGCCCATAAAGTGGAGCACGAAAGCAGGACCCAGAATGGGAGGAGCTTCCA GAGGACCGGAACACTTGCCTTTGAGCGGGTCTACACTGCCAACCAGAACTGTGTAGATGC GTACCCCACTTTCCTCGCTGTGCTCTGGTCTGCGGGGCTACTTTGCAGCCAAGTTCCTGC TGCGTTTGCTGGACTGATGTACTTGTTTGTGAGGCAAAAGTACTTTGTCGGTTACCTAGG AGAGAGAACGCAGAGCACCCCTGGCTACATATTTGGGAAACGCATCATACTCTTCCTGTT CCTCATGTCCGTTGCTGGCATATTCAACTATTACCTCATCTTCTTTTTCGGAAGTGACTT TGAAAACTACATAAAGACGATCTCCACCACCATCTCCCCTCTACTTCTCATTCCCTAACT CTCTGCTGAATATGGGGTTGGTGTTCTCATCTAATCAATACCTACAAGTCATCATAATTC AGCTCTTGAGAGCATTCTGCTCTTCTTTAGATGGCTGTAAATCTATTGGCCATCTGGGCT TCACAGCTTGAGTTAACCTTGCTTTTCCGGGAACAAAATGATGTCATGTCAGCTCCGCCC CTTGAACATGACCGTGGCCCCCAAATTTGCTATTCCCATGCATTTTGNTTGGTTCTTCAC TTATCCTGTTCTCTGAAGATGTTTTGTGACCAGGTTTTGTGGTTTCTTTAAATAAAAAGC AGAGACATGTTTTATAAAAAAAAAAAAAACTCGACTCTAGATTGGGGCGCGGTCTAGCTG TTTCCTGAACAATCCCGGGTGGGAATCCTGTGACCCCTTCCCATGGCTN |
Restriction Sites | NotI-NotI |
ACCN | NM_001629 |
Insert Size | 800 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001629.2, NP_001620.2 |
RefSeq Size | 873 bp |
RefSeq ORF | 486 bp |
Locus ID | 241 |
UniProt ID | P20292 |
Domains | MAPEG |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) encodes the predominant isoform (1). |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC203785 | ALOX5AP (Myc-DDK-tagged)-Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1 |
CNY 1,200.00 |
|
RC203785L1 | Lenti ORF clone of Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
RC203785L2 | Lenti ORF clone of Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC203785L3 | Lenti ORF clone of Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
RC203785L4 | Lenti ORF clone of Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1, mGFP tagged |
CNY 3,600.00 |
|
RG203785 | ALOX5AP (tGFP-tagged) - Human arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1 |
CNY 2,800.00 |