Caveolin 1 (CAV1) (NM_001753) Human Untagged Clone

Name: Caveolin 1 (CAV1) (NM_001753) Human Untagged Clone
SKU: SC119082
Price: 2400.00

CAT＃: SC119082

CAV1 (untagged)-Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1

Datasheet

SDS

"NM_001753" in other vectors (6)

CNY 2,400.00

CNY 2,950.00

货期*

现货

规格

Cited in 7 publications.

Product images

经常一起买 (4)

TA812677

CAV1 mouse monoclonal antibody,clone OTI2C4

CNY 1,999.00
CNY 2,700.00

【特别福利】购一抗正装产品（≥50ul或≥50ug），免费领10ul抗体试用装

TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

CNY 4,090.00

CC100003

DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)

CNY 1,280.00

PRIMER

Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each

CNY 480.00

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for NM_001172895 edited GAATTCGGCACGAGGCTCCTCACAGTTTTCATCCAGCCACGGGCCAGCATGTCTGGGGGC AAATACGTAGACTCGGAGGGACATCTCTACACCGTTCCCATCCGGGAACAGGGCAACATC TACAAGCCCAACAACAAGGCCATGGCAGACGAGCTGAGCGAGAAGCAAGTGTACGACGCG CACACCAAGGAGATCGACCTGGTCAACCGCGACCCTAAACACCTCAACGATGACGTGGTC AAGATTGACTTTGAAGATGTGATTGCAGAACCAGAAGGGACACACAGTTTTGACGGCATT TGGAAGGCCAGCTTCACCACCTTCACTGTGACGAAATACTGGTTTTACCGCTTGCTGTCT GCCCTCTTTGGCATCCCGATGGCACTCATCTGGGGCATTTACTTCGCCATTCTCTCTTTC CTGCACATCTGGGCAGTTGTACCATGCATTAAGAGCTTCCTGATTGAGATTCAGTGCATC AGCCGTGTCTATTCCATCTACGTCCACACCGTCTGTGACCCACTCTTTGAAGCTGTTGGG AAAATATTCAGCAATGTCCGCATCAACTTGCAGAAAGAAATATAAATGACATTTCAAGGA TAGAAGTATACCTGATTTTTTTTCCTTTTAATTTTCCTGTCAAGTTCCAAGTTGCTAATA CAGCAACAATTTATGAATTGAATTATCTTGGTTGAAAATAAAAAGATCACTTTCTCAGTT TTCATAAGTATTATGTCTCTTCTGAGCTATTTCATCTATTTTTGGCAGTCTGAATTTTTA AAACCCATTTAAATTTTTTTCCTTACCTTTTTATTTGCATGTGGATCAACCATCGCTTTA TTGGCTGAGATATGAACATATTGTTGAAAGGTAATTTGAGAGAAATATGAAGAACTGAGG AGGAAAAAAAAAAAAAAGAAAAGAACCAACAACCTCAACTGCCTACTCCAAAATGTTGGT CATTTTATGTTAAGGGAAGAATTCCAGGGTATGGCCATGGAGTGTACAAGTATGTGGGCA GATTTTCAGCAAACTCTTTTCCCACTGTTTAAGGAGTTAGTGGATTACTGCCATTCACTT CATAATCCAGTAGGATCCAGTGATCCTTACAAGTTAGAAAACATAATCTTCTGCCTTCTC ATGATCCAACTAATGCCTTACTCTTCTTGAAATTTTAACCTATGATATTTTCTGTGCCTG AATATTTGTTATGTAGATAACAAGACCTCAGTGCCTTCCTGTTTTTCACATTTTCCTTTT CAAATAGGGTCTAACTCAGCAACTCGCTTTAGGTCAGCAGCCTCCCTGAAGACCAAAATT AGAATATCCATGACCTAGTTTTCCATGCGTGTTTCTGACTCTGAGCTACAGAGTCTGGTG AAGCTCACTTCTGGGCTTCATCTGGCAACATCTTTATCCGTAGTGGGTATGGTTGACACT AGCCCAATGAAATGAATTAAAGTGGACCAATAGGGCTGAGCTCTCTGTGGGCTGGCAGTC CTGGAAGCCAGCTTTCCCTGCCTCTCATCAACTGAATGAGGTCAGCATGTCTATTCAGCT TCGTTTATTTTCAAGAATAATCACGCTTTCCTGAATCCAAACTAATCCATCACCGGGGTG GTTTAGTGGCTCAACATTGTGTTCCCATTTCAGCTGATCAGTGGGCCTCCAAGGAGGGGC TGTAAAATGGAGGCCATTGTGTGAGCCTATCAGAGTTGCTGCAAACCTGACCCCTGCTCA GTAAAGCACTTAAAAGATTGAAGTATTTTGCTGGAATAAGTTCAAATTCTTCTGAACTCA AACTGAGGAATTTCACCTGTAAACCTGAGTCGTACAGAAAGCTGCCTGGTATATCCAAAA GCTTTTTATTCCTCCTGCTCATATTGTGATTCTGCCTTTGGGGACTTTTCTTAAACCTTC AGTTATGATTTTTTTTTCATACACTTATTGGAACTCTGCTTGATTTTTGCCTCTTCCAGT CTTCCTGACACTTTAATTACCAACCTGTTACCTACTTTGACTTTTTGCATTTAAAACAGA CACTGGCATGGATATAGTTTTACTTTTAAACTGTGTACATAACTGAAAATGTGCTATACT GCATACTTTTTAAATGTAAAGATATTTTTATCTTTATATGAAGAAAATCACTTAGGAAAT GGCTTTGTGATTCAATCTGTAAACTGTGTATTCCAAGACATGTCTGTTCTACATAGATGC TTAGTCCCTCATGCAAATCAATTACTGGTCCAAAAGATTGCTGAAATTTTATATGCTTAC TGATATATTTTACAATTTTTTATCATGCATGTCCTGTAAAGGTTACAAGCCTGCACAATA AAAATGTTTAACGGTTAAAAAAAAAAAAAAAAAACTCGAC 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_001753 unedited TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCCTCACAGTTTTC ATCCAGCCACGGGCCAGCATGTCTGGGGGCAAATACGTAGACTCGGAGGGACATCTCTAC ACCGTTCCCATCCGGGAACAGGGCAACATCTACAAGCCCAACAACAAGGCCATGGCAGAC GAGCTGAGCGAGAAGCAAGTGTACGACGCGCACACCAAGGAGATCGACCTGGTCAACCGC GACCCTAAACACCTCAACGATGACGTGGTCAAGATTGACTTTGAAGATGTGATTGCAGAA CCAGAAGGGACACACAGTTTTGACGGCATTTGGAAGGCCAGCTTCACCACCTTCACTGTG ACGAAATACTGGTTTTACCGCTTGCTGTCTGCCCTCTTTGGCATCCCGATGGCACTCATC TGGGGCATTTACTTCGCCATTCTCTCTTTCCTGCACATCTGGGCAGTTGTACCATGCATT AAGAGCTTCCTGATTGAGATTCAGTGCATCAGCCGTGTCTATTCCATCTACGTCCACACC GTTTGTGACCCACTCTTTGAAGCTGTTGGGAAAATATTCAGCAATGTCCGCATCACCTTG CAGAAAGAAATATAAATGACATTTTCAGGATAGAAGTATACCTGATTTTTTTTTCCTTTT AATCTTCCTGTCAAGTTCCAAGTTGCTAATACAGCAACAATTTATGAATTGAATTACCTC GGTTGAAAAAAAAAGATCACTTTCTCAGTTTTCATAAGAATTATGCTCTTCTGAGCTATT TCATCTATTTTGGGCAGCCTGAATTTTAAAACCCCATTAAATTTTTTCCCTTCCCTTTTT ATTTGAAGGGGGAACAACCATCCCTTTATTGGCTGGAGAAATCAACTACTGTGTGGAGAG TTATTTGGGCAAAATTTTGACAAACTGGGGAGGAAAAAAAAACAAGAAATGCAC 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_001753 unedited ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACCGTTAAACATTTT TATTGTGCAGGCTTGTAACCTTTACAGGACATGCATGATAAAAAATTGTAAAATATATCA GTAAGCATATAAAATTTCAGCAATCTTTTGGACCAGTAATTGATTTGCATGAGGGACTAA GCATCTATGTAGAACAGACATGTCTTGGAATACACAGTTTACAGATTGAATCACAAAGCC ATTTCCTAAGTGATTTTCTTCATATAAAGATAAAAATATCTTTACATTTAAAAAGTATGC AGTATAGCACATTTTCAGTTATGTACACAGTTTAAAAGTAAAACTATATCCATGCCAGTG TCTGTTTTAAATGCAAAAAGTCAAAGTAGGTAACAGGTTGGTAATTAAAGTGTCAGGAAG ACTGGAAGAGGCAAAAATCAAGCAGAGTTCCAATAAGTGTATGAAAAAAAAATCATAACT GAAGGTTTAAGAAAAGTCCCCAAAGGCAGAATCACAATATGAGCAGGAGGAATAAAAAGC TTTTGGATATACCAGGCAGCTTTCTGTACGACTCAGGTTTACAGGTGAAATTCCTCAGTT TGAGTTCAGAAGAATTTGAACTTATTCCAGCAAAATACTTCAATCTTTTAAGTGCTNTAC TGAGCANGGGTCANGGTTGCAGCAACTCTGATAGGCTCACACAATGGCCTNCATTTTACA GCCCCTCCTTGGNAGGCCACTGATCAGCTGAAATGGGAAACACATGNTGAGCCACTAAAC CACCCCGGTGATGGGATAGTTTGGATCAGGAAAGCGTGATTATTCTGAAAATAACGAGCT GAATAGACTGCTGACCTCATCANTGATGAGAGCAGGNAAAGCTGCTTNCAGATGNCAGCC ACAGAGAGCTAGCCTATGGNNCCTTNNATCATTCATGGGCTANGTCACCTCACACTACGA TAAGATGTGCGATGAGCCAAAGTGGACTACCAACTTTGTGCTAAGTCGAAACAGCTGAAA CTAGC
Restriction Sites	NotI-NotI
ACCN	NM_001753
Insert Size	2400 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	A TrueClone.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001753.3, NP_001744.2
RefSeq Size	2704 bp
RefSeq ORF	537 bp
Locus ID	857
UniProt ID	Q03135
Domains	Caveolin
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Focal adhesion, Viral myocarditis
Gene Summary	The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] Transcript Variant: This variant (1) encodes the longer isoform (alpha).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (7)

The use of this cDNA Clones has been cited in the following citations:
Caveolin‐1 inhibition mediates the opposing effects of alcohol on γ‐secretase activity in arterial endothelial and smooth muscle cells ,null, Physiological Reports ,PubMed ID 36635975 [CAV1]
Caveolin-1 enhances rapid mucosal restitution by activating TRPC1-mediated Ca2+ signaling ,Rathor, N;Chung, HK;Wang, SR;Wang, JY;Turner, DJ;Rao, JN;, Physiol Rep ,PubMed ID 25367694 [Cav1]
Rift Valley Fever Virus Strain MP-12 Enters Mammalian Host Cells via Caveola-Mediated Endocytosis ,Brooke Harmon, Benjamin R. Schudel, Dianna Maar, Carol Kozina, Tetsuro Ikegami, Chien-Te Kent Tseng, and Oscar A. Negrete, J. Virol., Dec 2012; 86: 12954 - 12970. [CAV1]
CpG island shore methylation regulates caveolin-1 expression in breast cancer ,X Rao, J Evans, H Chae, J Pilrose, S Kim, P Yan, R-L Huang, H-C Lai, H Lin, Y Liu, D Miller, J-K Rhee, Y-W Huang, F Gu, J W Gray, TH-M Huang & K P Nephew, Oncogene doi:10.1038/onc.2012.474 [CAV1]
Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis ,Fang Yu, Lu Sun, and Khaled Machaca, J. Cell Biol., Nov 2010; 191: 523 - 535 [CAV1]
HIV infection upregulates Caveolin 1 (Cav-1) expression to restrict virus production ,Shanshan Lin, Xiao Mei Wang, Peter E. Nadeau, and Ayalew Mergia, J. Virol., Sep 2010; 84: 9487 - 9496 [CAV1]
Caveolin-1 modulates HIV-1 envelope induced bystander apoptosis through gp41 ,Xiao Mei Wang, Peter E. Nadeau, Yung-Tsun Lo, and Ayalew Mergia, J. Virol., Jul 2010; 84: 6515 - 6526 [CAV1]

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
TrueORF SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

Other Versions

SKU	Description	Size	Price
RC210274	CAV1 (Myc-DDK-tagged)-Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1	10 ug 产品选项验证失败所有选项都是必需的	CNY 2,400.00 CNY 3,705.00
RC210274L1	Lenti ORF clone of Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1, Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,800.00 CNY 5,890.00
RC210274L2	Lenti ORF clone of Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1, mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,800.00
RC210274L3	Lenti ORF clone of Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1, Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,800.00 CNY 5,890.00
RC210274L4	Lenti ORF clone of Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1, mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,800.00 CNY 5,890.00
RG210274	CAV1 (tGFP-tagged) - Human caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,000.00 CNY 4,370.00

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