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DR1 (NM_001938) Human Untagged Clone
CAT＃: SC118958
DR1 (untagged)-Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NC2; NC2-BETA; NC2B; NCB2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001938, the custom clone sequence may differ by one or more nucleotides
ATGGCTTCCTCGTCTGGCAACGATGATGATCTCACTATCCCCAGAGCTGCTATCAATAAAATGATCAAAG AGACTCTTCCTAATGTCCGGGTGGCCAACGATGCTCGAGAGCTGGTGGTGAACTGCTGCACTGAATTCAT TCACCTTATATCTTCTGAAGCCAATGAGATTTGTAACAAATCGGAAAAGAAGACCATCTCACCAGAGCAT GTCATACAAGCACTAGAAAGTTTGGGATTTGGCTCTTACATCAGTGAAGTAAAAGAAGTCTTGCAAGAGT GTAAAACAGTAGCATTAAAAAGAAGAAAGGCCAGTTCTCGTTTGGAAAACCTTGGCATTCCTGAAGAAGA GTTATTGAGACAGCAACAAGAATTATTTGCAAAAGCTAGACAGCAACAAGCAGAATTGGCCCAACAGGAA TGGCTTCAAATGCAGCAAGCTGCCCAACAAGCCCAGCTTGCTGCTGCCTCAGCCAGTGCATCTAATCAGG CGGGATCTTCTCAGGATGAAGAAGATGATGATGATATCTGA >OriGene 5' read for NM_001938 unedited
AATCGACTCATAAGGGCGGCCGCGAATTCGGCACGAGGCACACGCGAGTGTTCCCAGCCC TCAAGCCAGCTGCTCCTCCGTTCATTTTCTGCACCCTCTTCGCAAAGCACCCCCCGGGAT CACTTCTCCGAGGGCGAACTTTTTGAGAAATCTCGGTGGAGTAGTGGACCAGAGCTGGGG AGTTTTTAAAAGCCGGGGCGCGAGAAAAGGAAGGTACTATGGCTTCCTCGTCTGGCAACG ATGATGATCTCACTATCCCCAGAGCTGCTATCAATAAAATGATCAAAGAGACTCTTCCTA ATGTCCGGGTGGCCAACGATGCTCGAGAGCTGGTGGTGAACTGCTGCACTGAATTCATTC ACCTTATATCTTCTGAAGCCAATGAGATTTGTAACAAATCGGAAAAGAAGACCATCTCAC CAGAGCATGTCATACAAGCACTAGAAAGTTTGGGATTTGGCTCTTACATCAGTGAAGTAA AAGAAGTCTTGCAAGAGTGTAAAACAGTAGCATTAAAAAAGAAAAAAGGCCAGTTCTCGT TTGGAAAACCTTGGCATTCCTGAAGAAAAATTATTGAGACAGCAACAAGAATTATTTGCA AAAGCTAGACAGCAACAAGCAGAATTGGCCCAACAGGAATGGCTTCAAATGCAGCAAGCT GCCCAACAAGCCCAGCTTGCTGCTGCCTCAGCCAGTGCATCTAATAGGGCGGGATCTTCT CAGATGAAAAAAAGATGATGATATCTGAAATTCACAGCTGAGTTCTATTTCTTTAATAAT GTTNNTCNCTGACAACAAAAAAGTGAAGAAATGCTAATCTGTATTNTGTATGCATCTGGN NGGGACTGTCATTGTATCTAAGGGATGCTGCTATAAAGTCATCNATNGGNGCTATAAGNA AAACTGCTCTTTGACATGAAAAATTAGGNTAGATATATCATNTGATNTTTAA >OriGene 3' read for NM_001938 unedited
GTACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTAAAACACATCAC AATTTTATTGCTTGAAGATACAGCATATGAAATCACAAGAATGTCAAAATGAAAAGTCAC TAGGCTTCAAACGTATAATACATTATCAGATGCAGTAAAATATTAACCTGAACTCTGCAT CAGAAAAAAAAAAAAAAGTGTGGAAAATATCTAAGTTGTTTACCCTTAAGAAACAGATAT ACTTAAAATAGAAAGTATAAGGATGTTACAGTACAAATTAGAAAAGCCAACACGTATTAA CTTATCGTTCTAGACTAAACTACCTTTGGTACTTAAACTTTTTAAAAAACAATTTCTATC TCATCCAAATGCACTTCATGGGTATGACATCCATGAAGTAACTTTCACTTAAACATTCAG CANAATTAACCTTTTCACTTCATGGGGGAANGTATATTTAATAAATGTATAACAANTATT TCCCTTTTACTAAAACTGCAAAATATGATCATTAAGAAACCTAACAGTTATAAAACTTTA CTTACTTAGCTCTNCATTTAAAATGGGAATCCTGGAGGCACAATCTATTTTTGGGCTNGG TGAATACATAAGTTAANAAGATTGGGCACTGACATAGAATTAATACTTATACTATCTAGN GACTTTTCCTTCTGGTTCAAATATGAACATATGCCTTTCTTCACTCCTGAATTCTATATA CTACATACTGTATTATTAAACCAATTAAGCTCTCTACAGCAGGTGAACTTTTATGTTCTA TTCGCTGATAGTTTACCCAACTATGTCATTAGCTGACAATAATCTTAGGGTGACAATGAA AAACTNTTAACAAATAATTTTTTTAGCCTCCCTATTGGGACATATTGCTCTAAAGGAGTT GACTCGCCTTTTTGGGAAGGTATGTTTTAAACTAGNACTACCCCGTATAAACCTTTTACA GTGCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001938 |
| Insert Size | 2800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001938.2, NP_001929.1 |
| RefSeq Size | 3222 bp |
| RefSeq ORF | 531 bp |
| Locus ID | 1810 |
| UniProt ID | Q01658 |
| Domains | CBFD_NFYB_HMF |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205733 | DR1 (Myc-DDK-tagged)-Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1) |
CNY 2,400.00 |
|
| RC205733L1 | Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC205733L2 | Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mGFP tagged |
CNY 5,890.00 |
|
| RC205733L3 | Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205733L4 | Lenti ORF clone of Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mGFP tagged |
CNY 5,890.00 |
|
| RG205733 | DR1 (tGFP-tagged) - Human down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1) |
CNY 4,000.00 |
