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FOXO1 (NM_002015) Human Untagged Clone
CAT＃: SC118890
FOXO1 (untagged)-Human forkhead box O1 (FOXO1)
CNY 7,328.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FKH1; FKHR; FOXO1A |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002015 edited
ATGGCCGAGGCGCCTCAGGTGGTGGAGATCGACCCGGACTTCGAGCCGCTGCCCCGGCCG CGCTCGTGCACCTGGCCGCTGCCCAGGCCGGAGTTTAGCCAGTCCAACTCGGCCACCTCC AGCCCGGCGCCGTCGGGCAGCGCGGCTGCCAACCCCGACGCCGCGGCGGGCCTGCCCTCG GCCTCGGCTGCCGCTGTCAGCGCCGACTTCATGAGCAACCTGAGCTTGCTGGAGGAGAGC GAGGACTTCCCGCAGGCGCCCGGCTCCGTGGCGGCGGCGGTGGCGGCGGCGGCCGCCGCG GCCGCCACCGGGGGGCTGTGCGGGGACTTCCAGGGCCCGGAGGCGGGCTGCCTGCACCCA GCGCCACCGCAGCCCCCGCCGCCCGGGCCGCTGTCGCAGCACCCGCCGGTGCCCCCCGCC GCCGCTGGGCCGCTCGCGGGGCAGCCGCGCAAGAGCAGCTCGTCCCGCCGCAACGCGTGG GGCAACCTGTCCTACGCCGACCTCATCACCAAGGCCATCGAGAGCTCGGCGGAGAAGCGG CTCACGCTGTCGCAGATCTACGAGTGGATGGTCAAGAGCGTGCCCTACTTCAAGGATAAG GGTGACAGCAACAGCTCGGCGGGCTGGAAGAATTCAATTCGTCATAATCTGTCCCTACAC AGCAAGTTCATTCGTGTGCAGAATGAAGGAACTGGAAAAAGTTCTTGGTGGATGCTCAAT CCAGAGGGTGGCAAGAGCGGGAAATCTCCTAGGAGAAGAGCTGCATCCATGGACAACAAC AGTAAATTTGCTAAGAGCCGAAGCCGAGCTGCCAAGAAGAAAGCATCTCTCCAGTCTGGC CAGGAGGGTGCTGGGGACAGCCCTGGATCACAGTTTTCCAAATGGCCTGCAAGCCCTGGC TCTCACAGCAATGATGACTTTGATAACTGGAGTACATTTCGCCCTCGAACTAGCTCAAAT GCTAGTACTATTAGTGGGAGACTCTCACCCATTATGACCGAACAGGATGATCTTGGAGAA GGGGATGTGCATTCTATGGTGTACCCGCCATCTGCCGCAAAGATGGCCTCTACTTTACCC AGTCTGTCTGAGATAAGCAATCCCGAAAACATGGAAAATCTTTTGGATAATCTCAACCTT CTCTCATCACCAACATCATTAACTGTTTCGACCCAGTCCTCACCTGGCACCATGATGCAG CAGACGCCGTGCTACTCGTTTGCGCCACCAAACACCAGTTTGAATTCACCCAGCCCAAAC TACCAAAAATATACATATGGCCAATCCAGCATGAGCCCTTTGCCCCAGATGCCTATACAA ACACTTCAGGACAATAAGTCGAGTTATGGAGGTATGAGTCAGTATAACTGTGCGCCTGGA CTCTTGAAGGAGTTGCTGACTTCTGACTCTCCTCCCCATAATGACATTATGACACCAGTT GATCCTGGGGTAGCCCAGCCCAACAGCCGGGTTCTGGGCCAGAACGTCATGATGGGCCCT AATTCGGTCATGTCAACCTATGGCAGCCAGGTATCTCATAACAAAATGATGAATCCCAGC TCCCATACCCACCCTGGACATGCTCAGCAGACATCTGCAGTTAACGGGCGTCCCCTGCCC CACACGGTAAGCACCATGCCCCACACCTCGGGTATGAACCGCCTGACCCAAGTGAAGACA CCTGTACAAGTGCCTCTGCCCCACCCCATGCAGATGAGTGCCCTGGGGGGCTACTCCTCC GTGAGCAGCTGCAATGGCTATGGCAGAATGGGCCTTCTCCACCAGGAGAAGCTCCCAAGT GACTTGGATGGCATGTTCATTGAGCGCTTAGACTGTGACATGGAATCCATCATTCGGAAT GACCTCATGGATGGAGATACATTGGATTTTAACTTTGACAATGTGTTGCCCAACCAAAGC TTCCCACACAGTGTCAAGACAACGACACATAGCTGGGTGTCAGGCTGA >OriGene 5' read for NM_002015 unedited
CTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGTCGCAGCA GCCGCTGCCGCAGCCGCCACATTCAACAGGCAGCAGCGCAGCGGGCGCGCCGCTGGGGAG AGCAAGCGGCCCGCGGCGTCCGTCCGTCCTTCCGTCCGCGGCCCTGTCAGCTGGAGCGCG GCGCAGGCTCTGCCCCGGCCCGGCGGCTCTGGCCGGCCGTCCAGTCCGTGCGGCGGACCC CGAGGAGCCTCGATGTGGATGGCCCCGCGAAGTTAAGTTCTGGGCTCGCGCTTCCACTCC GCCGCGCCTTCCTCCCAGTTTCCGTCCGCTCGCCGCACCGGCTTCGTTCCCCCAAATCTC GGACCGTCCCTTCGCGCCCCCTCCCCGTCCGCCCCCAGTGCTGCGTTCTCCCCCTCTTGG CTCTCCTGCGGCTGGGGGAGGGGCGGGGGTCACCATGGCCGAGGCGCCTCAGGTGGTGGA GATCGACCCGGACTTCGAGCCGCTGCCCCGGCCGCGCTCGTGCACCTGGCCGCTGCCCAG GCCGGAGTTTAGCCAGTCCAACTCGGCCACCTCCAGCCCGGCGCCGTCGGGCAGCGCGGC TGCCAACCCCGACGCCGCGGCGGGCCTGCCCTCGGCCTCGGCTGCCGCTGTCAGCGCCGA CTTCATGAGCAACCTGAGCTTGCTGGAGGAGAGCGAGGACTTNNCCGCAGCGCCCGGCTC CGTGGCGGCGGCGGGGGCGGNCGGCGGCCGCCCGCGGCCGNCACCGGNGGGGCTGTGCGG GGACTTCCAGGCCCCGGGAGGGCGGGCTGGCTGCACCCAAGCCACCGAAGCCCCGCCGNC CGGGCCGCTGTCGCACAACCCGCCGTTGCCCCCGCCGCCGCTGGGCCCTTCCGGGGCAAC CGCGCAGTACCATTTGTCCCGCGCACACGGTGGGGGAACCTGTCTACGCCGACTTATACC AAGCCACGAAGCTCT >OriGene 3' read for NM_002015 unedited
TAGGAAACTAAAGGGCAGTTGTGTGAAGNACTCTTTGGACTGCTTCTCTCAGTTCCTGCT GTCAGACAATCTGAAGTACTTTTAAGTGTAACCTGCTCACTAACCCTCAGCCTGACACCC AGCTATGTGTCGTTGTCTTGACACTGTGTGGGAAGCTTTGGTTGGGCAACACATTGTCAA AGTTAAAATCCAATGTATCTCCATCCATGAGGTCATTCCGAATGATGGATTCCATGTCAC AGTCTAAGCGCTCAATGAACATGCCATCCAAGTCACTTGGGAGCTTCTCCTGGTGGAGAA GGCCCATTCTGCCATAGCCATTGCAGCTGCTCACGGAGGAGTAGCCCCCCAGGGCACTCA TCTGCATGGGGTGGGGCAGAGGCACTTGTACAGGTGTCTTCACTTGGGTCAGGCGGTTCA TACCCGAGGTGTGGGGCATGGTGCTTACCGTGTGGGGCAGGGGACGCCCGTTAACTGCAG ATGTCTGCTGAGCATGTCCAGGGTGGGTATGGGAGCTGGGATTCATCATTTTGTTATGAG ATACCTGGCTGCCATAGGTTGACATGACCGAATTAGGGCCCATCATGACGTTCTGGCCCA GAACCCGGCTGTTGGGCTGGGCTACCCCAGGATCAACTGGTGTCATAATGTCATTATGGG GAGGAGAGTCAGAAGTCAGCAACTCCTTCAAAGAGTCCAGCGCACAGTTATACTGACTCA TACCTNCATACCTCGACTTATTGTCCTGAAATGTTTGTATAGGCATCTGGGGGCAAGGGC TCATGCTGNATNGGCCATATGTATATTTTTGGTAGTTTGGGCTGGGTGAATTCAAACTGG TGTTTGTGGCGCAAACGATTACACGGCGTCTGCTGATCAATGTGCCCAGTGAGGACTGGG CTGAACAGTTATGATTTTGTGATGACACAAGTTGAGATTTCAAAGATTTCCTGTTTCTGG ATTGCTATTTACAAGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002015 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002015.2, NP_002006.2 |
| RefSeq Size | 5723 bp |
| RefSeq ORF | 1968 bp |
| Locus ID | 2308 |
| UniProt ID | Q12778 |
| Domains | FH |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Insulin signaling pathway, Pathways in cancer, Prostate cancer |
| Gene Summary | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Akt3 inhibits adipogenesis and protects from diet-induced obesity via WNK1/SGK1 signaling
,Ding, L;Zhang, L;Biswas, S;Schugar, RC;Brown, JM;Byzova, T;Podrez, E;,
JCI Insight
,PubMed ID 29202451
[FOXO1]
|
|
Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells.
,null,
Cancer letters
,PubMed ID 24576622
[FOXO1]
|
|
The Antiapoptotic Function of miR-96 in Prostate Cancer by Inhibition of FOXO1
,Fendler, A;Jung, M;Stephan, C;Erbersdobler, A;Jung, K;Yousef, GM;,
PLoS ONE e80807
,PubMed ID 24260486
[FOXO1]
|
|
The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors
,Ahmed Essaghir, Nicolas Dif, Catherine Y. Marbehant, Paul J. Coffer, and Jean-Baptiste Demoulin,
J. Biol. Chem., Feb 2009; 10.1074/jbc.M808848200.
[FOXO1]
|
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200477 | FOXO1 (Myc-DDK-tagged)-Human forkhead box O1 (FOXO1) |
CNY 7,312.00 |
|
| RC200477L1 | Lenti ORF clone of Human forkhead box O1 (FOXO1), Myc-DDK-tagged |
CNY 9,712.00 |
|
| RC200477L2 | Lenti ORF clone of Human forkhead box O1 (FOXO1), mGFP tagged |
CNY 9,712.00 |
|
| RC200477L3 | Lenti ORF clone of Human forkhead box O1 (FOXO1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200477L4 | Lenti ORF clone of Human forkhead box O1 (FOXO1), mGFP tagged |
CNY 9,712.00 |
|
| RG200477 | FOXO1 (tGFP-tagged) - Human forkhead box O1 (FOXO1) |
CNY 8,912.00 |
