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FKBP52 (FKBP4) (NM_002014) Human Untagged Clone
CAT＃: SC118889
FKBP4 (untagged)-Human FK506 binding protein 4, 59kDa (FKBP4)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FKBP51; FKBP52; FKBP59; HBI; Hsp56; p52; PPIase |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118889 sequence for NM_002014 edited (data generated by NextGen Sequencing)
ATGACAGCCGAGGAGATGAAGGCGACCGAGAGCGGGGCGCAGTCGGCGCCGCTGCCCATG GAGGGAGTGGACATCAGCCCCAAACAGGACGAAGGCGTGCTGAAGGTCATCAAGAGAGAG GGCACAGGTACAGAGATGCCCATGATTGGGGACCGAGTCTTTGTCCACTACACTGGCTGG CTATTAGATGGCACAAAGTTTGACTCCAGTCTGGATCGCAAGGACAAATTCTCCTTTGAC CTGGGAAAAGGGGAGGTCATCAAGGCTTGGGACATTGCCATAGCCACCATGAAGGTGGGG GAGGTGTGCCACATCACCTGCAAACCAGAATATGCCTACGGTTCAGCAGGCAGTCCTCCA AAGATTCCCCCCAATGCCACGCTTGTATTTGAGGTGGAGTTGTTTGAGTTTAAGGGAGAA GATCTGACGGAAGAGGAAGATGGCGGAATCATTCGCAGAATACAGACTCGCGGTGAAGGC TATGCTAAGCCCAATGAGGGTGCTATCGTGGAGGTTGCACTGGAAGGGTACTACAAGGAC AAGCTCTTTGACCAGCGGGAGCTCCGCTTTGAGATTGGCGAGGGGGAGAACCTGGATCTG CCTTATGGTCTGGAGAGGGCCATTCAGCGCATGGAGAAAGGAGAACATTCCATCGTGTAC CTCAAGCCCAGCTATGCTTTTGGCAGTGTTGGGAAGGAAAAGTTCCAAATCCCACCAAAT GCTGAGCTGAAATATGAATTACACCTCAAGAGTTTTGAAAAGGCCAAGGAGTCTTGGGAG ATGAATTCAGAAGAGAAGCTGGAACAGAGCACCATAGTGAAAGAGCGGGGCACTGTGTAC TTCAAGGAAGGTAAATACAAGCAAGCTTTACTACAGTATAAGAAGATCGTGTCTTGGCTG GAATATGAGTCTAGTTTTTCCAATGAGGAAGCACAGAAAGCACAGGCCCTTCGACTGGCC TCTCACCTCAACCTGGCCATGTGTCATCTGAAACTACAGGCCTTCTCTGCTGCCATTGAA AGCTGTAACAAGGCCCTAGAACTGGACAGCAACAACGAGAAGGGCCTCTTCCGCCGGGGA GAGGCCCACCTGGCCGTGAATGACTTTGAACTGGCACGGGCTGATTTCCAGAAGGTCCTG CAGCTCTACCCCAACAACAAAGCCGCCAAGACCCAGCTGGCTGTGTGCCAGCAGCGGATC CGAAGGCAGCTTGCCCGGGAGAAGAAGCTCTATGCCAATATGTTTGAGAGGCTGGCTGAG GAGGAGAACAAGGCCAAGGCAGAGGCTTCCTCAGGAGACCATCCCACTGACACAGAGATG AAGGAGGAGCAGAAGAGCAACACGGCAGGGAGCCAGTCTCAGGTGGAGACAGAAGCATAG Clone variation with respect to NM_002014.3 >OriGene 5' read for NM_002014 unedited
GCTAGATTTTGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCCCGG ATAAACGGCGCGCCGCGCGGAGATGACAGCCGAGGAGATGAAGGCGACCGAGAGCGGGGC GCAGTCGGCGCCGCTGCCCATGGAGGGAGTGGACATCAGCCCCAAACAGGACGAAGGCGT GCTGAAGGTCATCAAGAGAGAGGGCACAGGTACAGAGATGCCCATGATTGGGGACCGAGT CTTTGTCCACTACACTGGCTGGCTATTAGATGGCACAAAGTTTGACTCCAGTCTGGATCG CAAGGACAAATTCTCCTTTGACCTGGGAAAAGGGGAGGTCATCAAGGCTTGGGACATTGC CATAGCCACCATGAAGGTGGGGGAGGTGTGCCACATCACCTGCAAACCAGAATATGCCTA CGGTTCAGCAGGCAGTCCTCCAAAGATTCCCCCCAATGCCACGCTTGTATTTGAGGTGGA GTTGTTTGAGTTTAAGGGAGAAGATCTGACGGAAGAGGAAGATGGCGGAATCATTCGCAG AATACAGACTCGCGGTGAAGGCTATGCTAAGCCCAATGAGGGTGCTATCGTGGAGGTTGC ACTGGAAGGGTACTACAAGGACAAGCTCTNTGACCAGCGGGAGCTCCGCTTTGAGATTGG CGAGGGGGAGAACCTGGATCTGCCTTATGGTCTGGAGAGGGCCATTCAGCGCATGGAGAA AGGGAGACATTCCATCGTGTACCTCAAGCCAGCTATGCTTTTGGCAGTNGTGGGAAGGAA AAGTTTCCAATCCCACCAATGCTGAGCTGAATATGAATTACACCTCAGAAGTTTGAAAAG CCCAGGAGTCTTGGGAGAATGATTCAGAAAGAAAGCTGGAACAGNACACCATAGTGAAAG ACGGGGCACTGTGTACTCCAGGGAAGGTAATACCAGCAAGCTTTACTANCAGTATAGAAA GATCGG >OriGene 3' read for NM_002014 unedited
GACCGCGGCCGTTTCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTTCCACTTTATTGCT CAAGCATGGAACTTGAGGCAAGCCTGGACCTTCAGCAACGTGCAGAGAAGAGGCTGAGGG GATTTTGGGACACAACCTGGCCGAGAGGGGAAACTGACAGGGGAAATACCAGAACAGGGA ACAGGGGGTGGTCACCATGACACCAGAAGACATCATCAGCCACACCGTCGGGGGTGAGGA AGGGAACAGAGAGAAGAAATGGCATAGCAGTGGTTTTTCCCATGTCCCTAGCACCCACAT GGAGGCCACATTTGGAAATGGACTGGGAGAGGGAAAGGATGAGGAAAACGGCTGCCCAGG AGTCTCCCTCTCCACCCTGGGTTCTTATCAGACCTCATCCCTACCACTTGCCTTTTCTAC CCTTAGAAAATGGACCTAACAGAGGGAGCAAAATAAATTAACATTCTGATGAATATATAT GGATGGACATATGTTCATGTGCAATGGAAGGAAGGGAAAAGGGGCTGACACCATCTAAAA TGATTCCCCAACCTAATTCCCCCACCCTAAACCTTTTCCCCCTTCCCCTTAAGCCCCCCT TCCCACCCGTATGGAAATAAAAGGGGTTCATTCCTCCAAATTTTTCAATTTTTTCAAAAA AACCAGGGCTGAACGGGGAATCTGGGGGCCAGCACCCCCCAAAATAGGCCTTTGGAAAGA GGTTTTCTTTTTTTCCCCCCCCTAAAAAGGTCCCCGCCCCGGAGCGCTCTTTCGGTCCCT CTTTTCCTTTACGGCCCCATGGTGTTTTCTTCTAGAAACTATCTTCTCCCCTCTTTTCTT CCCTCCACCCCCCCCCTCAAAAAATTGTGAAAAATCTTCTTCCTCCCACCCCATCTCTTC TTTCATTACGGCTCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002014 |
| Insert Size | 2250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002014.2, NP_002005.1 |
| RefSeq Size | 2251 bp |
| RefSeq ORF | 1380 bp |
| Locus ID | 2288 |
| UniProt ID | Q02790 |
| Domains | FKBP, TPR |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200713 | FKBP4 (Myc-DDK-tagged)-Human FK506 binding protein 4, 59kDa (FKBP4) |
CNY 3,656.00 |
|
| RC200713L1 | Lenti ORF clone of Human FK506 binding protein 4, 59kDa (FKBP4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC200713L2 | Lenti ORF clone of Human FK506 binding protein 4, 59kDa (FKBP4), mGFP tagged |
CNY 6,056.00 |
|
| RC200713L3 | Lenti ORF clone of Human FK506 binding protein 4, 59kDa (FKBP4), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200713L4 | Lenti ORF clone of Human FK506 binding protein 4, 59kDa (FKBP4), mGFP tagged |
CNY 5,890.00 |
|
| RG200713 | FKBP4 (tGFP-tagged) - Human FK506 binding protein 4, 59kDa (FKBP4) |
CNY 5,256.00 |
