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FES (NM_002005) Human Untagged Clone
CAT＃: SC118883
FES (untagged)-Human feline sarcoma oncogene (FES), transcript variant 1
CNY 6,032.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FPS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118883 sequence for NM_002005 edited (data generated by NextGen Sequencing)
ATGGGCTTCTCTTCCGAGCTGTGCAGCCCCCAGGGCCACGGGGTCCTGCAGCAAATGCAG GAGGCCGAGCTTCGTCTACTGGAGGGCATGAGAAAGTGGATGGCCCAGCGGGTCAAGAGT GACAGGGAGTATGCAGGACTGCTTCACCACATGTCCCTGCAGGACAGTGGGGGCCAGAGC CGGGCCATCAGCCCTGACAGCCCCATCAGTCAGTCCTGGGCTGAGATCACCAGCCAAACT GAGGGCCTGAGCCGCTTGCTGCGGCAGCACGCAGAGGATCTGAACTCAGGGCCCCTGAGC AAGCTGAGCCTGCTCATCCGGGAACGGCAGCAGCTTCGCAAGACCTACAGCGAGCAGTGG CAGCAGCTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGCTGAAGAGC CAGTACCGAGCTCTGGCACGGGACAGTGCCCAAGCCAAGCGCAAGTACCAGGAGGCCAGC AAAGACAAGGACCGTGACAAGGCTAAGGACAAGTATGTGCGCAGCCTGTGGAAGCTCTTT GCTCACCACAACCGCTATGTGCTGGGCGTGCGGGCTGCGCAGCTACACCACCAGCACCAC CACCAGCTCCTGCTGCCCGGCCTGCTGCGGTCACTGCAGGACCTGCACGAGGAGATGGCT TGCATCCTGAAGGAGATCCTGCAGGAATACCTGGAGATTAGCAGCCTGGTGCAGGATGAG GTGGTGGCCATTCACCGGGAGATGGCTGCAGCTGCTGCCCGCATCCAGCCTGAGGCTGAG TACCAAGGCTTCCTGCGACAGTATGGGTCCGCACCTGACGTCCCACCCTGTGTCACGTTC GATGAGTCACTGCTTGAGGAGGGTGAACCGCTGGAGCCTGGGGAGCTCCAGCTGAACGAG CTGACTGTGGAGAGCGTGCAGCACACGCTGACCTCAGTGACAGATGAGCTGGCTGTGGCC ACCGAGATGGTGTTCAGGCGGCAGGAGATGGTTACGCAGCTGCAACAGGAGCTCCGGAAT GAAGAGGAGAACACCCACCCCCGGGAGCGGGTGCAGCTGCTGGGCAAGAGGCAAGTGCTG CAAGAAGCACTGCAGGGGCTGCAGGTAGCGCTGTGCAGCCAGGCCAAGCTGCAGGCCCAG CAGGAGTTGCTGCAGACCAAGCTGGAGCACCTGGGCCCCGGCGAGCCCCCGCCTGTGCTG CTCCTGCAGGATGACCGCCACTCCACGTCGTCCTCGGAGCAGGAGCGAGAGGGGGGAAGG ACACCCACGCTGGAGATCCTTAAGAGCCACATCTCAGGAATCTTCCGCCCCAAGTTCTCG CTCCCTCCACCGCTGCAGCTCATTCCGGAGGTGCAGAAGCCCCTGCATGAGCAGCTGTGG TACCACGGGGCCATCCCGAGGGCAGAGGTGGCTGAGCTGCTGGTGCACTCTGGGGACTTC CTGGTGCGGGAGAGCCAGGGCAAGCAGGAGTACGTGCTGTCGGTGCTGTGGGATGGTCTG CCCCGGCACTTCATCATCCAGTCCTTGGATAACCTGTACCGACTGGAAGGGGAAGGCTTT CCTAGCATTCCTTTGCTCATCGACCACCTACTGAGCACCCAGCAGCCCCTCACCAAGAAG AGTGGTGTTGTCCTGCACAGGGCTGTGCCCAAGGACAAGTGGGTGCTGAACCATGAGGAC CTGGTGTTGGGTGAGCAGATTGGACGGGGGAACTTTGGCGAAGTGTTCAGCGGACGCCTG CGAGCCGACAACACCCTGGTGGCGGTGAAGTCTTGTCGAGAGACGCTCCCACCTGACCTC AAGGCCAAGTTTCTACAGGAAGCGAGGATCCTGAAGCAGTACAGCCACCCCAACATCGTG CGTCTCATTGGTGTCTGCACCCAGAAGCAGCCCATCTACATCGTCATGGAGCTTGTGCAG GGGGGCGACTTCCTGACCTTCCTCCGCACGGAGGGGGCCCGCCTGCGGGTGAAGACTCTG CTGCAGATGGTGGGGGATGCAGCTGCTGGCATGGAGTACCTGGAGAGCAAGTGCTGCATC CACCGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTCCTGAAGATCAGT GACTTTGGGATGTCCCGAGAGGAAGCCGATGGGGTCTATGCAGCCTCAGGGGGCCTCAGA CAAGTCCCCGTGAAGTGGACCGCACCTGAGGCCCTTAACTACGGCCGCTACTCCTCCGAA AGCGACGTGTGGAGCTTTGGCATCTTGCTCTGGGAGACCTTCAGCCTGGGGGCCTCCCCC TATCCCAACCTCAGCAATCAGCAGACACGGGAGTTTGTGGAGAAGGGGGGCCGTCTGCCC TGCCCAGAGCTGTGTCCTGATGCCGTGTTCAGGCTCATGGAGCAGTGCTGGGCCTATGAG CCTGGGCAGCGGCCCAGCTTCAGCACCATCTACCAGGAGCTGCAGAGCATCCGAAAGCGG CATCGGTGA Clone variation with respect to NM_002005.3 >OriGene 5' read for NM_002005 unedited
TCATAATTTGTAATACACTACTATAGGCGGCCGCGAATTCGGCACCAGCCCAAGAGCAGC TGCCCGTGCGGGTACCTCTAGCCCCGGGGCCTGGAGGAGCGGTGGGAGCTGGGGGCGCGG CAGGCAGGGGCAGAGCAGGCGTTCCGAGGGCCAGAGACCCACCCAGAACAGCACTATGGG CTTCTCTTCCGAGCTGTGCAGCCCCCAAGGCCACGGGGTCCTGCAGCAAATGCAGGAGGC CGAGCTTCGTCTACTGGAGGGCATGAGAAAGTGGATGGCCCAGCGGGTCAAGAGTGACAA GGGAGTATGCAGGACTGCTTCACCACATGTCCCTGCAGGACAGTGGGGGCCAGATCCGGG CCATCAGCCCTGACAGCCCCATCAGTCAGTCCTGGGCTGAGATCAACCAGCCAAACTGAG GGCCTGAGCCGCTTGCTGCGGCAGCACGCAGAAGATCTGAACTCAGGGCCCCTGAGCAAG CTGAGCCTGCTCATCCGGGAACGGCAGCAGCTTCGCAAGAACTACAGCGAGCAGTGGCAG CAGCTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGCTGAAGAACCAG TACCGAGCTCTGGCACGGGACAGTGCCCAAGCCAAGCGCAAGTACCATGAGGCCAGCAAA ACAANGACCGTGACAAGGCTAAGACAAGTATGTGCGCAGCCTGTGGAATCTCTTTGCTCA CCACAACCGCTATGTGCTTGGGCGTGCGGGCTGCGCATCTACACCACCATCAAACCACCA TCTCTGCTGCCGGNCTGCTGCGGTACTGCAAGACTGCAGAANGAGAATGCTGATNCTGAA AGAAANCTGCAGAATACTGGAAATTACANCTGTGCAGAATAAGGGGTGCCATTCACCGGA AAGGCTGAGCTGCTGCCGCATCAACTGAGCTGATACAAGCTCTGGAAATATGGTCGAACT GACTCACTTGGTAGTTNA >OriGene 3' read for NM_002005 unedited
GGACCCTAAGGGTGATGGCACCTNCCTGCNAGGTANATCACTGGCGNAGGGTCACAGGGC ATGCCACCCGGGCTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT TTTTTTTTTTTTTTTTTTCAGTGGGCACAAGTGGTTTTATTGTTTCTGCCCGGAAGAGGA AGCCCTGGCAGCAGCAGGGACACAGAGAGGACACGGCTCTTTTTCCTGCCGGCAGTGTGG ATGCTGGTGGCAGGAGTCCAGGACTGTGAAGAGCTGTCAGCATATGAGCTGGAGCCGCTG ATGAGCTGCACCTAGGCCTGCAGAGGCCACCAGCTTGAGAAGGGGGTCCCAGCCTCACCG ATGCCGCTTTCGGATGCTCTGCAGCTCCTGGTATATGGTGCTGAAGCTGGGCCGCTGCCC AGGCTCATAGGCCCAGCTCTGCTCCATGAGCCTGAACACGGCATCAGGACACAGCTCTGG GCAGGGCAGACGGCCCCCCTTCTCCACAAACTCCCGTGTCTGCTGATTGCTGAGGTTGGG ATAGGGGGAGGCCCCCAGGCTGAAGGTCTCCCTTAGCAAGATGCCTAAGCTCCACATTTC GCTTTCGGAGGAGTAGCGGCCGTAGTTAAGGGCCTCAAGTGCGGTCCACTTCACGGGGGA CTTGTCTGAGGCCCCCTGATGCTGCCTAGACCCTATGGGCTTCCTCTCGGGACATCCCAT AGTCACTGATCTTCAGGACATTCTTCTCTGTCCCCGGGCTTTTTCCGATCACCCAGGTCC CGGTGGGTGCAACTTTTGCTCTTCCGGTTCTCCTTGCCGCCGTTTGTTTCCCCCCCCCTC TGGTCGGTATTCTCACCCGCGGTCGGCCCCCCTTCTTCCGGNGGAAGGTAAGGATTCCCC ACCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002005 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002005.2, NP_001996.1 |
| RefSeq Size | 2762 bp |
| RefSeq ORF | 2469 bp |
| Locus ID | 2242 |
| UniProt ID | P07332 |
| Domains | pkinase, SH2, FCH, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Axon guidance |
| Gene Summary | This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A New Signaling Pathway (JAK-Fes-phospholipase D) That Is Enhanced in Highly Proliferative Breast Cancer Cells
,Qing Ye, Samuel Kantonen, Karen M. Henkels, and Julian Gomez-Cambronero,
J. Biol. Chem., Apr 2013; 288: 9881 - 9891.
,PubMed ID 23404507
[FES]
|
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High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia
,Marc M Loriaux, Ross L Levine, Jeffrey W Tyner, Stefan Frohling, Claudia Scholl, Eric P Stoffregen, Gerlinde Wernig, Heidi Erickson, Christopher A Eide, Roland Berger, Olivier A. Bernard, James D. Griffin, Richard M Stone, Benjamin Lee, Matthew Meyerson, Michael C Heinrich, Michael W Deininger, D Gary Gilliland, and Brian J Druker,
Blood, Feb 2008; 10.1182/blood-2007-07-101394
[FES]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206408 | FES (Myc-DDK-tagged)-Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 6,024.00 |
|
| RC206408L1 | Lenti-ORF clone of FES (Myc-DDK-tagged)-Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 8,424.00 |
|
| RC206408L2 | Lenti-ORF clone of FES (mGFP-tagged)-Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 5,890.00 |
|
| RC206408L3 | Lenti-ORF clone of FES (Myc-DDK-tagged)-Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 5,890.00 |
|
| RC206408L4 | Lenti-ORF clone of FES (mGFP-tagged)-Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 5,890.00 |
|
| RG206408 | FES (tGFP-tagged) - Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 4,370.00 |
|
| SC323596 | FES (untagged)-Kinase deficient mutant (K590M) of Human feline sarcoma oncogene (FES), transcript variant 1 |
CNY 6,032.00 |
