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HLA-DOA (NM_002119) Human Untagged Clone
CAT＃: SC118845
HLA (untagged)-Human major histocompatibility complex, class II, DO alpha (HLA-DOA)
CN¥ 2,400.00
CN¥ 2,950.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HLA-DNA; HLA-DZA; HLADZ |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118845 sequence for NM_002119 edited (data generated by NextGen Sequencing)
ATGGCCCTCAGAGCAGGGCTGGTCCTGGGGTTCCACACCCTGATGACCCTCCTGAGCCCG CAGGAGGCAGGGGCCACCAAGGCTGACCACATGGGCTCCTACGGACCCGCCTTCTACCAG TCTTACGGCGCCTCGGGCCAGTTCACCCATGAATTTGATGAGGAACAGCTGTTCTCTGTG GACCTGAAGAAAAGCGAGGCCGTGTGGCGTCTGCCTGAGTTTGGTGACTTTGCCCGCTTT GACCCGCAGGGTGGGCTGGCCGGCATCGCCGCAATCAAAGCCCATCTGGACATCCTGGTG GAGCGCTCCAACCGCAGCAGAGCCATCAACGTGCCTCCACGGGTGACCGTGCTCCCCAAG TCTCGGGTGGAGCTGGGCCAGCCCAACATCCTCATCTGCATCGTGGACAACATCTTCCCC CCTGTGATCAATATCACCTGGCTACGCAACGGCCAAACTGTCACTGAGGGAGTGGCCCAG ACCAGCTTCTATTCCCAGCCTGACCATTTGTTCCGCAAGTTCCACTACCTGCCCTTCGTG CCCTCAGCCGAGGACGTCTATGACTGCCAGGTGGAGCACTGGGGCCTGGATGCGCCACTC CTCAGGCATTGGGAGCTCCAGGTGCCTATTCCACCACCAGATGCCATGGAGACCCTGGTC TGTGCCCTGGGCCTGGCCATCGGCCTGGTGGGCTTCCTCGTGGGCACCGTCCTCATCATC ATGGGCACATATGTGTCCAGTGTCCCCAGGTAA Clone variation with respect to NM_002119.3 252 c=>t;444 g=>a >OriGene 5' read for NM_002119 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGATTAAAGCACCAGA GTGTAATGGCCCTCAGAGCAGGGCTGGTCCTGGGGTTCCACACCCTGATGACCCTCCTGA GCCCGCAGGAGGCAGGGGCCACCAAGGCTGACCACATGGGCTCCTACGGACCCGCCTTCT ACCAGTCTTACGGCGCCTCGGGCCAGTTCACCCATGAATTTGATGAGGAACAGCTGTTCT CTGTGGACCTGAAGAAAAGCGAGGCCGTGTGGCGTCTGCCTGAGTTTGGTGACTTTGCCC GCTTTGACCCGCAGGGTGGGCTGGCCGGCATCGCCGCAATCAAAGCCCATCTGGACATCC TGGTGGAGCGCTCCAACCGCAGCAGAGCCATCAACGTGCCTCCACGGGTGACCGTGCTCC CCAAGTCTCGGGTGGAGCTGGGCCAGCCCAACATCCTCATCTGCATCGTGGACAACATCT TCCCCCCTGTGATCAATATCACCTGGCTACGCAACGGCCAAACTGTCACTGAGGGAGTGG CCCAGACCAGCTTCTATTCCCAGCCTGACCATTTGTTCCGCAAGTTCCACTACCTGCCCT TCGTGCCCTCAGCCGAGGACGTCTATGACTGCCAGGTGGAGCACTGGGGCCTGGATGCGC CACTCCTCAGGCATTGGGAGCTCCAGGTGCCTATTCCACCACCAGATGCCATGGAGACCC TGGTCTGTGCCCTGGGCCTGGGCCATCGCCTGGTGGGCTTCCTCGTGGGCACCGTCCTCA TCATCATGGGCACATATGTGTCCAGTGTCCCCCAGTATGATCCTTCTGAGAGAAATGACT GTAGGAGACACCCTGCAGATCTCATGGGNTTGTGACAGCCCCTGCGTGCTCAGTGCCCTT TAGTGCATNCCGCTGTGCTGACTTGNANTGGGATCACATN >OriGene 3' read for NM_002119 unedited
GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTCTTTAGTCAAAAAAACACAATT TTAATGACTTTATCAAGCCTTAGGACAGAGATGAGAGAAACACCTTTCCAATGATGCATC AAGTTAACGTCTAAGCAAAAGATCAGCAGAGATCAGAGATTGTTGGGTACACACGTATCT TGTGATGTCTTCTGAGAACCAACTTATTCCTCTTTCTCTGAGAAGAACTTGACCCCTCGC CCCGGGGCTGAGTGCTTGGCAGCCACATTTGTGTTGAGATCTTGATTCCTGCTCTAACTA CACAGGGCTGGGATGGACACCTGCTCCAAGTTTGGCCAGTCATTTATTTTTCCAGTAATT TAAAGCTGTGACTAGGAGACACAGCCTCTGTGGGTTGTGAGGGTTGAGATGATATAAACT CAGGAGCTGTCGGGTGGACATGTTCACTGAGAAGGACAGTCAGTCCACAGAGAGAGAACA CCGCTAACATGCAGGGGGGTCTAGAGAACACAGACCATGTGGATCCGAGAGTGTTGGAGG GGCAGCTCTAGCTTCTCTGGGCTTTTCGGATCCGAGTTCTGTTCCTGGGAGGCCTGGCTA AAATCTACCCCTTGGGCCCTGCACTCCTCCCCATTGGCTATATTGCAAATATCCTATACT TTGCATGTGATCACACAAAGAGGGTTTCTGTTACTGCCCCACAAAAAGTTTGGCCTGAGA TGATATTCCTCCACTTCCATCAGGCTCCTCTTGCTCATTGATTTCACCTTATTCCCTCTC AGAAGGCCAACTGAGCCCCATAATCTTTGTTTTCTTTTTTTCCAGGACAACTGCTTAAGT NTAAACCTTTATTTGCCTTTATTACTGCACCTGATTGGCTGAGCCCTACCGACCACGGTT TTAAAAACCTTTCTTATCACTTCAACTTGGGATCCCTTTCCTGACCCCGTGGACTGTTCG TACTGGGTCAGTACAAACAAGCAAGCCCGATGGGCTAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002119 |
| Insert Size | 3520 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002119.3, NP_002110.1 |
| RefSeq Size | 3485 bp |
| RefSeq ORF | 753 bp |
| Locus ID | 3111 |
| UniProt ID | P06340 |
| Domains | MHC_II_alpha, ig, IGc1 |
| Protein Families | Transmembrane |
| Protein Pathways | Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis |
| Gene Summary | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203816 | HLA (Myc-DDK-tagged)-Human major histocompatibility complex, class II, DO alpha (HLA-DOA) |
CN¥ 2,400.00 |
|
| RC203816L3 | Lenti ORF clone of Human major histocompatibility complex, class II, DO alpha (HLA-DOA), Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC203816L4 | Lenti ORF clone of Human major histocompatibility complex, class II, DO alpha (HLA-DOA), mGFP tagged |
CN¥ 5,890.00 |
|
| RG203816 | HLA (tGFP-tagged) - Human major histocompatibility complex, class II, DO alpha (HLA-DOA) |
CN¥ 4,000.00 |
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