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Integrin beta 8 (ITGB8) (NM_002214) Human Untagged Clone
CAT＃: SC118752
ITGB8 (untagged)-Human integrin, beta 8 (ITGB8)
CNY 28,472.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002214, the custom clone sequence may differ by one or more nucleotides
ATGTGCGGCTCGGCCCTGGCTTTTTTTACCGCTGCATTTGTCTGCCTGCAAAACGACCGGCGAGGTCCCG CCTCGTTCCTCTGGGCAGCCTGGGTGTTTTCACTTGTTCTTGGACTGGGCCAAGGTGAAGACAATAGATG TGCATCTTCAAATGCAGCATCCTGTGCCAGGTGCCTTGCGCTGGGTCCAGAATGTGGATGGTGTGTTCAA GAGGATTTCATTTCAGGTGGATCAAGAAGTGAACGTTGTGATATTGTTTCCAATTTAATAAGCAAAGGCT GCTCAGTTGATTCAATAGAATACCCATCTGTGCATGTTATAATACCCACTGAAAATGAAATTAATACCCA GGTGACACCAGGAGAAGTGTCTATCCAGCTGCGTCCAGGAGCCGAAGCTAATTTTATGCTGAAAGTTCAT CCTCTGAAGAAATATCCTGTGGATCTTTATTATCTTGTTGATGTCTCAGCATCAATGCACAATAATATAG AAAAATTAAATTCCGTTGGAAACGATTTATCTAGAAAAATGGCATTTTTCTCCCGTGACTTTCGTCTTGG ATTTGGCTCATACGTTGATAAAACAGTTTCACCATACATTAGCATCCACCCCGAAAGGATTCATAATCAA TGCAGTGACTACAATTTAGACTGCATGCCTCCCCATGGATACATCCATGTGCTGTCTTTGACAGAGAACA TCACTGAGTTTGAGAAAGCAGTTCATAGACAGAAGATCTCTGGAAACATAGATACACCAGAAGGAGGTTT TGACGCCATGCTTCAGGCAGCTGTCTGTGAAAGTCATATCGGATGGCGAAAAGAGGCTAAAAGATTGCTG CTGGTGATGACAGATCAGACGTCTCATCTCGCTCTTGATAGCAAATTGGCAGGCATAGTGGTGCCCAATG ACGGAAACTGTCATCTGAAAAACAACGTCTATGTCAAATCGACAACCATGGAACACCCCTCACTAGGCCA ACTTTCAGAGAAATTAATAGACAACAACATTAATGTCATCTTTGCAGTTCAAGGAAAACAATTTCATTGG TATAAGGATCTTCTACCCCTCTTGCCAGGCACCATTGCTGGTGAAATAGAATCAAAGGCTGCAAACCTCA ATAATTTGGTAGTGGAAGCCTATCAGAAGCTCATTTCAGAAGTGAAAGTTCAGGTGGAAAACCAGGTACA AGGCATCTATTTTAACATTACCGCCATCTGTCCAGATGGGTCCAGAAAGCCAGGCATGGAAGGATGCAGA AACGTGACGAGCAATGATGAAGTTCTTTTCAATGTAACAGTTACAATGAAAAAATGTGATGTCACAGGAG GAAAAAACTATGCAATAATCAAACCTATTGGTTTTAATGAAACCGCTAAAATTCATATACACAGAAACTG CAGCTGTCAGTGTGAGGACAACAGAGGACCTAAAGGAAAGTGTGTAGATGAAACTTTTCTAGATTCCAAG TGTTTCCAGTGTGATGAGAATAAATGTCATTTTGATGAAGATCAGTTTTCTTCTGAGAGTTGCAAGTCAC ACAAGGATCAGCCTGTTTGCAGTGGTCGAGGAGTTTGTGTTTGTGGGAAATGTTCATGTCACAAAATTAA GCTTGGAAAAGTGTATGGAAAATACTGTGAAAAGGATGACTTTTCTTGTCCATATCACCATGGAAATCTG TGTGCTGGGCATGGAGAGTGTGAAGCAGGCAGATGCCAATGCTTCAGTGGCTGGGAAGGTGATCGATGCC AGTGCCCTTCAGCAGCAGCCCAGCACTGTGTCAATTCAAAGGGCCAAGTGTGCAGTGGAAGAGGCACGTG TGTGTGTGGAAGGTGTGAGTGCACCGATCCCAGGAGCATCGGCCGCTTCTGTGAACACTGCCCCACCTGT TATACAGCCTGCAAGGAAAACTGGAATTGTATGCAATGCCTTCACCCTCACAATTTGTCTCAGGCTATAC TTGATCAGTGCAAAACCTCATGTGCTCTCATGGAACAACAGCATTATGTCGACCAAACTTCAGAATGTTT CTCCAGCCCAAGCTACTTGAGAATATTTTTCATCATTTTCATAGTTACATTCTTGATTGGGTTGCTTAAA GTCCTGATCATTAGACAGGTGATACTACAATGGAATAGTAATAAAATTAAGTCCTCATCAGATTACAGAG TGTCAGCCTCAAAAAAGGATAAGTTGATTCTGCAAAGTGTTTGCACAAGAGCAGTCACCTACCGACGTGA GAAGCCTGAAGAAATAAAAATGGATATCAGCAAATTAAATGCTCATGAAACTTTCAGGTGCAACTTCTAA >OriGene 5' read for NM_002214 unedited
GGGCGGCCCGCGAATTCGCACGAGGGGACTGCGGGACGCCTGAGCCGCGCACTGAGGCGA AAAGGACAAGGGCACGCAGCCCCCGCCCCGCGAAGCCGGGCTCCGGCACCTCGCGGAACC TCCCCTCCTGCGCTCGCAGCCGCAGGCCCCACTCCCCGCCAGGGAGGGAGCGGCGATGCC TCGCTCTGTGCCTGCGGGTGTCGGCGGGTGCTTCTAGGGCGCTCCCAGAGCCGCCTCCCC CTGTTGCTGGCATCCCGAGCTTCCTCCCTTGCCAGCCAGGACGCTGCCGACTTGTCTTTG CCCGCTGCTCCGCAGACGGGGCTGCAAAGCTGCAACTAATGGTGTTGGCCTCCCTGCCCA CCTGTGGAAGCAACTGCGCTGATTGATGCGCCACAGACTTTTTTCCCCTCGACCTCGCCG GCGTCCCCTCCCACAGATCCAGCATCACCCAGTGAATGTACATTAGGGTGGTTTCCCCCC CAGCTTCGGGCTTTGTTTGGGTTTGATTGTGTTTGGCTCTTCGCTAAGCTGATTTATGCA GCAGAAGCCCCACCGGCTGGAGAGAAACAAAAGCTCTTTTCTTTGTCCAGGAGCANGCTG CGGAGCCCTTGCAGAGCCCTCTCTCCAGTCGCCGCCGGAGCCCTTGGCCGTCGAAGGAAG TGCTTCTCGCGGAGACCGCGGGACCCGCCGTGCCGAGCCGGGAGGGCCGCAGGGGCCCTG AGATGCCGAGCGGTGCCCGGGCCCGCTTACCTGCACCGCTTGCTCCCGAGCCGGGGGTCC GNCTGCTNAGCCTGCNGAAAACGTCCTANCGACACTCGGNCCGCGGGCCCCGAGGTGCGC CGCGGAGGCGCGAGCCCCGGTCCGGAAGGAANCAGCCGGCGGCCGCGGGCGGGCTGTTTG CATTAGTGCGCCTCGCCCTG >OriGene 3' read for NM_002214 unedited
GTTTACTTGNACCCGGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTTGAAAGAT GAAACACGAATCATTTATTCATCTAGCTGTTCTTGTCTATTCAACCACCAACTGTTGAAG TGTTTGGCAACCTTAGAATATACTTGCCAGATTATTTTTTTCCTCACATGTCCAGTGCAG GGATTACTGTACCCTTGTAGTGACACAATGCTAAACTCTCTCACAGCATTGTTCTCTCTG GGAAGCGTAGGGATAACAGGTACCTGTAAAGTGTAATCAGTGCTCTTCAGAGGATCTACA TTCTATGCTGATCTAAATAAGTTATATATTACAGTAAAGTGCTACAACGACACTAGTCTC AAACAGTAGTAAGACACATTTTTCTCTGAAAAAGTCAGCAGCTATGTGAGTCACATCATG ATGAGGATACTTGTCAGTCTTCGTTCGAGTGTACAACCAGCAACTGGCATGACCGTGAGC AATTTGCCTCCTCCTGTGACTTTTAAAATTATAATCTTTAGGAGCAATTATTAACAATTC CAGTCTTCCCATTAAGTGTTTAAAAATCCTTTTTTACAAGTCGCACCTGAAAGCCCATGA GCCTTCAATCCCGCTGCTATCCATTCTTATTTCCTCAGGCCTCTCACGTCCGTAGGCGAT CGCTCTTGGGCCAACACTTTGCAGAATCAACCTATCCTTTTTTGAGGCTGCCCCTCTGCC ATCCCCGCAGGCCCCAACGCCCCCAGCACCCCCCTCGCAATCTCCACCTGCCCAATGATC CAGGATTTTCACTCATCCCCATTTCCAATGCTCCCCTTCTACTGATGAAATACCTCCCCC GGTAGCTTGTCTTGCACCACAATTCCTTAGCCCTGTCATCTTATGCCTCTCTCCCCTTAC ACCACCCACGCCCCACCCTCAAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002214 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002214.1, NP_002205.1 |
| RefSeq Size | 8787 bp |
| RefSeq ORF | 8787 bp |
| Locus ID | 3696 |
| UniProt ID | P26012 |
| Domains | INB, PSI |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
| Gene Summary | This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222336 | ITGB8 (Myc-DDK-tagged)-Human integrin, beta 8 (ITGB8) |
CNY 8,448.00 |
|
| RC222336L1 | Lenti-ORF clone of ITGB8 (Myc-DDK-tagged)-Human integrin, beta 8 (ITGB8) |
CNY 10,848.00 |
|
| RC222336L2 | Lenti-ORF clone of ITGB8 (mGFP-tagged)-Human integrin, beta 8 (ITGB8) |
CNY 10,070.00 |
|
| RC222336L3 | Lenti-ORF clone of ITGB8 (Myc-DDK-tagged)-Human integrin, beta 8 (ITGB8) |
CNY 10,848.00 |
|
| RC222336L4 | Lenti-ORF clone of ITGB8 (mGFP-tagged)-Human integrin, beta 8 (ITGB8) |
CNY 10,848.00 |
|
| RG222336 | ITGB8 (tGFP-tagged) - Human integrin, beta 8 (ITGB8) |
CNY 10,048.00 |
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