United States
Germany
Japan
United Kingdom
China
LSS (NM_002340) Human Untagged Clone
CAT＃: SC118683
LSS (untagged)-Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1
CNY 8,592.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APMR4; CTRCT44; HYPT14; OSC |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002340 edited
CCACGCGTCCGCCCACGCGTCCGGTAGAGCACTGCAGCAGCAATGACGGAGGGCACGTGT CTGCGGCGCCGAGGGGGCCCCTACAAGACCGAGCCCGCCACCGACCTCGGCCGCTGGCGA CTCAACTGCGAGAGGGGCCGGCAGACGTGGACCTACCTGCAGGACGAGCGCGCCGGCCGC GAGCAGACCGGCCTGGAAGCCTACGCCCTGGGGCTGGACACCAAGAATTACTTTAAGGAC TTGCCCAAAGCCCACACCGCCTTTGAGGGGGCTCTGAACGGGATGACATTTTACGTGGGG CTGCAGGCTGAGGATGGGCACTGGACGGGTGATTATGGTGGCCCACTTTTCCTCCTGCCA GGCCTCCTGATCACTTGCCACGTGGCACGCATCCCTCTGCCAGCCGGATACAGAGAAGAG ATTGTGCGGTACCTGCGGTCAGTGCAGCTCCCTGACGGTGGCTGGGGCCTGCACATTGAG GATAAGTCCACCGTGTTTGGGACTGCGCTCAACTATGTGTCTCTCAGAATTCTGGGTGTT GGGCCTGACGATCCTGACCTGGTACGAGCCCGGAACATTCTTCACAAGAAAGGTGGTGCT GTGGCCATCCCCTCCTGGGGGAAGTTCTGGCTGGCTGTCCTGAATGTTTACAGCTGGGAA GGCCTCAATACCCTGTTCCCAGAGATGTGGCTGTTTCCTGACTGGGCACCGGCACACCCC TCCACACTCTGGTGCCACTGCCGGCAGGTGTACCTGCCCATGAGCTACTGCTACGCCGTT CGGCTGAGTGCCGCGGAAGACCCGCTGGTCCAGAGCCTCCGCCAGGAGCTCTATGTGGAG GACTTCGCCAGCATTGACTGGCTGGCGCAGAGGAACAACGTGGCCCCCGACGAGCTGTAC ACGCCCCACAGCTGGCTGCTCCGCGTGGTATATGCGCTCCTCAACCTGTATGAGCACCAC CACAGTGCCCACCTGCGGCAGCGGGCCGTGCAGAAGCTGTATGAACACATTGTGGCCGAC GACCGATTCACCAAGAGCATCAGCATCGGCCCGATCTCGAAAACCATCAACATGCTTGTG CGCTGGTATGTGGACGGGCCCGCCTCCACTGCCTTCCAGGAGCATGTCTCCAGAATCCCG GACTATCTCTGGATGGGCCTTGACGGCATGAAAATGCAGGGCACCAACGGCTCACAGATC TGGGACACCGCATTCGCCATCCAGGCTCTGCTTGAGGCGGGCGGGCACCACAGGCCCGAG TTTTCGTCCTGCCTGCAGAAGGCTCATGAGTTCCTGAGGCTCTCACAGGTCCCAGATAAC CCTCCCGACTACCAGAAGTACTACCGCCAGATGCGCAAGGGTGGCTTCTCCTTCAGTACG CTGGACTGCGGCTGGATCGTTTCTGACTGCACGGCTGAGGCCTTGAAGGCTGTGCTGCTC CTGCAGGAGAAGTGTCCCCATGTCACCGAGCACATCCCCAGAGAACGGCTCTGCGATGCT GTGGCTGTGCTGCTGAACATGAGAAATCCAGATGGAGGGTTCGCCACCTATGAGACCAAG CGTGGGGGGCACTTGCTGGAGCTGCTGAACCCCTCGGAGGTCTTCGGGGACATCATGATT GACTACACCTATGTGGAGTGCACCTCAGCCGTGATGCAGGCGCTTAAGTATTTCCACAAG CGTTTCCCGGAGCACAGGGCAGCGGAGATCCGGGAGACCCTCACGCAGGGCTTAGAGTTC TGTCGGCGGCAGCAGAGGGCCGATGGCTCCTGGGAAGGCTCCTGGGGAGTTTGCTTCACC TACGGCACCTGGTTTGGCCTGGAGGCCTTCGCCTGTATGGGGCAGACCTACCGAGATGGG ACTGCCTGTGCAGAGGTCTCCCGGGCCTGTGACTTCCTGCTGTCCCGGCAGATGGCAGAC GGAGGCTGGGGGGAGGACTTTGAGTCCTGCGAGGAGCGGCGTTATGTGCAGAGTGCCCAG TCCCAGATCCATAACACATGCTGGGCCATGATGGGGCTGATGGCCGTTCGGCATCCTGAC ATCGAGGCCCAGGAGAGAGGAGTCCGGTGTCTACTTGAGAAACAGCTCCCCAATGGCGAC TGGCCGCAGGAAAACATTGCTGGGGTCTTCAACAAGTCCTGTGCCATCTCCTACACGAGC TACAGGAACATCTTCCCCATCTGGGCCCTCGGCCGCTTCTCCCAGCTGTACCCTGAGAGA GCCCTTGCTGGCCACCCCTGAGAACATGCCTACCTGCTGGGTGCCGTCTGTGCGTTCCAG TGAGGCCAAGGGGTCCTGGCCGGGTTGGGGAGCCCTCCCATAACCCTGTCTTGGGCTCCA ACCCCTCAACCTCTATCTCATAGATGTGAATCTGGGGGCCAGGCTGGAGGCAGGGATGGG GACAGGGTGGGTGGCTTAGACTCTTGATTTTTACTGTAGGTTCATTTCTGAAAGTAGCTT GTCGGGCTTGGGTGAGGAAGGGGGCACAGGAGCCGTGACCCCTGAGGAGGCACAGCGCCT TCTGCCACCTCTGGGCACGGCCTCAAGGTAGTGAGGCTAGGAGGTTTTTTCTGACCAATA GCTGAGTTCTTGGGAGAGGAGCAGCTGTGCCTGTGTGATTCCTTAGTGTCGAGTGGGCTC TGGGCTGGGGTCGGCCCTGGGCAGGCTTCTCCTGCACCTTTTGTCTGCTGGGCTGAGGGA CACGAGGGCAACCCTGTGACAATGGCAGGTAGTGTGCATCCGTGAATAGCCCAGTGCGGG GGTTGCTCATGGAGCATCCTGAGGCCGTGCAGCAGGGAGCCCCATGCCCCTGGGTCGTGA GCTTGCCTGCGTATGGGGTGGTGTCATGGAGCCTCATGCCCCTGGGTCGTGAGCTCGCCT GAGTATGGGGTGGTGTCATGGAGCCGCATACCCCTGGGTTGTGAGCTCGCCTGCATATGC AGGGTCTGTCATGGAACATCCCAAGTCTGTGCAGCAGGGAGCCCCATGCCCCTGGGACAT GAACCCACCTGCGTGGAATGCTGTTTGTGAGGTGTCTACAGGGTTTATAGTAGTCTTGTG GACACAGAAATGCACAGGGGACACTTACGGACACAGAAATGCACAGGGGAGGCCGAGCAT AACCAGGGGTGAGGGGCAGGCAGCAGTTGTAGTTACTGCCGCGGGGCACTGCTATGTGCA GGGACAGCCAGCGCCCAGCCCATCACCACTCCCTGGGCTGGCTGGCAGGTATGGCACCCT GGGAGCCCGGCATATACCCAGGGCACCCCTACGGCTGCCGCCAGTCTCATGCCCAGGTGG GTGCTCTGGGCTGGAGCGAGGGCCAGGTTTTGGGCCGAGGCTTCCCCAGGCAATCCTGTG AGCTCCCTTCTAGCCTCTGACCCAGTCTGGTCTGGCTTGCATGGATGTAGGGCTTGGGGT GGGAAGTTCAGGTCCTGGCTTTGCCTTTGCCTGATGTGGATGAGCAGCTCACATGCTCAG GGCCACCTGAGACTGTCACTGCTCTCCCCTGGCTACTGGGAGGAGTCACTGAGAGCTTCG TTACCCCTGCTGCCTTGCCCAGGGCACACCCTATACCTCCTCATCTGCTCTTCCCCTCCC TGCCGCCTTCTGGGCAGGTAGCAGTCCCTGGCCTCTCCCCCTGGCTGATCACTCTCCCTC AGGCAGTGGAGATCTGCGTCTGGACACCCTCAGATCCTGTCATTGCCTGCCCAGAGTCCT TCAGGGGCACCCCTCTGCCTTGGTGTGCGGTCCAGGGCTCTCACCCAGGTGCCGCACCCT CTGGGGTCTTCTGTCCAGCTCCCTTGCCCCATGTGCTGTCACTGACTCTCCTTGGGACTC GCCTGCCTGCTCAGAGCCCTGCAGGGCTTGGTCAGCTGCCTGTTCAGTGTCAACACTTCC CTGCACATCTTAAAACTGGGCTTTATTTTCGCTGAAGGAACTGTGTTGGGACCCTTGACA TCTGTCAGGTTTGCACATGCTGTTTTTTTTTCTCAGCCCACGTGTTCTCCCCCACGTGGG GTAGCAGCAGGACAGACAGTGAATCACAGAGTCTGCCCTGAGCAGAGGCTGCTGTCCCTG GGACTCCTAGCCATGGTCAGACTGTACAAAACGGTTTTCCAGAAATGAAATGTAAATCCA TTTTTATACTGAAAATGTTACTGAAAGTCACTTTTATGAGCATCTGCCTTAATAAACAGA CATTGATTCCCTTATCAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002340 |
| Insert Size | 4110 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002340.3, NP_002331.3 |
| RefSeq Size | 4225 bp |
| RefSeq ORF | 2199 bp |
| Locus ID | 4047 |
| UniProt ID | P48449 |
| Domains | prenyltrans |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Steroid biosynthesis |
| Gene Summary | The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009] Transcript Variant: This variant (1) differs in the 3' UTR, compared to variant 2. Variants 1 and 2 encode the same protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic and transcript sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207793 | LSS (Myc-DDK-tagged)-Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1 |
CNY 8,040.00 |
|
| RC207793L3 | Lenti-ORF clone of LSS (Myc-DDK-tagged)-Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1 |
CNY 5,890.00 |
|
| RC207793L4 | Lenti-ORF clone of LSS (mGFP-tagged)-Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1 |
CNY 5,890.00 |
|
| RG207793 | LSS (tGFP-tagged) - Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1 |
CNY 4,370.00 |
|
| SC322588 | LSS (untagged)-Human lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 1 |
CNY 8,056.00 |
