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NEUROD1 (NM_002500) Human Untagged Clone
CAT＃: SC118625
NEUROD1 (untagged)-Human neurogenic differentiation 1 (NEUROD1)
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BETA2; BHF-1; bHLHa3; MODY6; NEUROD; T2D |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002500, the custom clone sequence may differ by one or more nucleotides
ATGACCAAATCGTACAGCGAGAGTGGGCTGATGGGCGAGCCTCAGCCCCAAGGTCCTCCAAGCTGGACAG ACGAGTGTCTCAGTTCTCAGGACGAGGAGCACGAGGCAGACAAGAAGGAGGACGACCTCGAAGCCATGAA CGCAGAGGAGGACTCACTGAGGAACGGGGGAGAGGAGGAGGACGAAGATGAGGACCTGGAAGAGGAGGAA GAAGAGGAAGAGGAGGATGACGATCAAAAGCCCAAGAGACGCGGCCCCAAAAAGAAGAAGATGACTAAGG CTCGCCTGGAGCGTTTTAAATTGAGACGCATGAAGGCTAACGCCCGGGAGCGGAACCGCATGCACGGACT GAACGCGGCGCTAGACAACCTGCGCAAGGTGGTGCCTTGCTATTCTAAGACGCAGAAGCTGTCCAAAATC GAGACTCTGCGCTTGGCCAAGAACTACATCTGGGCTCTGTCGGAGATCCTGCGCTCAGGCAAAAGCCCAG ACCTGGTCTCCTTCGTTCAGACGCTTTGCAAGGGCTTATCCCAACCCACCACCAACCTGGTTGCGGGCTG CCTGCAACTCAATCCTCGGACTTTTCTGCCTGAGCAGAACCAGGACATGCCCCCCCACCTGCCGACGGCC AGCGCTTCCTTCCCTGTACACCCCTACTCCTACCAGTCGCCTGGGCTGCCCAGTCCGCCTTACGGTACCA TGGACAGCTCCCATGTCTTCCACGTTAAGCCTCCGCCGCACGCCTACAGCGCAGCGCTGGAGCCCTTCTT TGAAAGCCCTCTGACTGATTGCACCAGCCCTTCCTTTGATGGACCCCTCAGCCCGCCGCTCAGCATCAAT GGCAACTTCTCTTTCAAACACGAACCGTCCGCCGAGTTTGAGAAAAATTATGCCTTTACCATGCACTATC CTGCAGCGACACTGGCAGGGGCCCAAAGCCACGGATCAATCTTCTCAGGCACCGCTGCCCCTCGCTGCGA GATCCCCATAGACAATATTATGTCCTTCGATAGCCATTCACATCATGAGCGAGTCATGAGTGCCCAGCTC AATGCCATATTTCATGATTAG >OriGene 5' read for NM_002500 unedited
GGTTCACATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGGCGCG GCGTCCGGAGCCCCAGGTTATGAGACTATCACTGCTCAGGACCTACTAACAACAAAGGAA ATCGAAACATGACCAAATCGTACAGCGAGAGTGGGCTGATGGGCGAGCCTCAGCCCCAAG GTCCTCCAAGCTGGACAGACGAGTGTCTCAGTTCTCAGGACGAGGAGCACGAGGCAGACA AGAAGGAGGACGACCTCGAAACCATGAACGCAGAGGAGGACTCACTGAGGAACGGGGGAG AGGAGGAGGACGAAGATGAGGACCTGGAAGAGGAGGAAGAAGAGGAAGAGGAGGATGACG ATCAAAAGCCCAAGAGACGCGGCCCCAAAAAGAAGAAGATGACTAAGGCTCGCCTGGAGC GTTTTAAATTGAGACGCATGAAGGCTAACGCCCGGGAGCGGAACCGCATGCACGGACTGA ACGCGGCGCTAGACAACCTGCGCAAGGTGGTGCCTTGCTATTCTAAGACGCAGAAGCTGT CCAAAATCGAGACTCTGCGCTTGGCCAAGAACTACATCTGGGCTCTGTCGGAGATCCTGC GCTCAGGCAAAAGCCCAGACCTGGTCTCCTTCGTTCAGACGCTTTGCAAGGGCTTATCCC AACCCACCACCAACCCTGTTGCGGGCTGCCTGCAACTCAATCCTCGCACTCTTCTGCCTG AGCAGAACCAGGACACTGCCCCCCCACCTGCCCGACGGCCAACGCTTCCTTCCCTGTACC ACCCCTACTCCTACCATTCGCCTGGGCTTGCCAGTCCCGCCTACGGACCCATGGACAGCT CCCATGTCTTCCAGTTAAGCCCTCGCGNACGCCTACAGGGCAAGGCTGGAGCCCTCTTTG AAAGCCTCTGACTG >OriGene 3' read for NM_002500 unedited
ACGCGGCCGCATCTATATCGAGTTTTTTTTTTTTTTTTTTGCAATTGGAGAGGAAAGAAT GCTAAGGCAACACAATAACTTTCTAAGCACTTTTCTGCTGGTTTAAATTAGTTAAATTAT TTTGTATAAATTAGATATAATTCTACTTTTCTGATATGTATAAAAATTGATGAAGCTGCA TGGTTTTAAAATAGGAAATCCACATTATAAAAAGTCATTAAAAATTCTGTACAAAATCAC AACAAAATAATTCAGCATGGGAAAGGTAACAAGTAGTAAAATGCTGGTTGAAAAATATAT ATTTATATATATTTTAATTGGCCCATTACTAGTTTAAAAATTGCATAGATCCTAATTATT GCTTGTGATTTTGTTATCCCGATCAGATAATTAATACGATCTGAATACAGCCACACCAAA TTCGTGGTGTATTTTTTAAACTTTACTGTATTTTTTTATTTTTTAAATAGAAGAGCTATA GAAAATAATACATAAGGCGAACAGGAACTTTGATCCCCTGTTTCTTCCAAAGGCTGTAAT GACAATAAATACATATATCACTACAAGCTTGGAGTATTTGCACTTTGCAGCAGTAGTACC CAAAGGGCTGCCTTTTGTAAACACGACAGTCACTGTTAGCACAGTGGGTTCGTTTCCCGG AAATGGTGAAACTGGCGTGCCCTCTATCATGAAATATGGCATTGAGCTGGGCACTCATGA CTCGCTCATGATGTGAATGGCTATCGGACGACATAATATTGTCTATGGGGATCTCNCACC GAGGGGCAACGGTCGCCTGAAAATATTGATCCGCGGCCTTTGGCCCCCTGCCATGGTCCC TGCAGAATAATGCATGGTAAGGCTTATTTTTTTCCAACTCGGCGGACGTTCCGGGTTAAA AGAAAATTCCATTGTGCCTAACGGCGGCCTCAAGGGCCCTCAAAGGAAAGCTGGGCATTA TTCAAAGGCCTTTAAGAAGGCCCCACGCTTCCCTTAAGGCCCCGCGAAGCTTACCGGAAT ACTAGGAGCCCCC |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_002500 |
| Insert Size | 2020 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002500.1, NP_002491.1 |
| RefSeq Size | 3002 bp |
| RefSeq ORF | 1071 bp |
| Locus ID | 4760 |
| UniProt ID | Q13562 |
| Domains | HLH |
| Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
| Protein Pathways | Maturity onset diabetes of the young |
| Gene Summary | This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the protein-coding transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson’s disease
,null,
PLoS ONE
,PubMed ID 34941945
[NEUROD1]
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|
Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells
,Ikeda, R;Pak, K;Chavez, E;Ryan, AF;,
Mol. Neurobiol. July 2014
,PubMed ID 25015561
[NEUROD1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201987 | NEUROD1 (Myc-DDK-tagged)-Human neurogenic differentiation 1 (NEUROD1) |
CNY 5,488.00 |
|
| RC201987L1 | Lenti ORF clone of Human neurogenic differentiation 1 (NEUROD1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201987L2 | Lenti ORF clone of Human neurogenic differentiation 1 (NEUROD1), mGFP tagged |
CNY 7,888.00 |
|
| RC201987L3 | Lenti ORF clone of Human neurogenic differentiation 1 (NEUROD1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201987L4 | Lenti ORF clone of Human neurogenic differentiation 1 (NEUROD1), mGFP tagged |
CNY 7,888.00 |
|
| RG201987 | NEUROD1 (tGFP-tagged) - Human neurogenic differentiation 1 (NEUROD1) |
CNY 7,088.00 |
|
| SC324139 | NEUROD1 (untagged)-Human neurogenic differentiation 1 (NEUROD1) |
CNY 5,488.00 |
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