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P2X1 (P2RX1) (NM_002558) Human Untagged Clone
CAT＃: SC118594
P2RX1 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 1 (P2RX1)
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | P2X1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118594 sequence for NM_002558 edited (data generated by NextGen Sequencing)
ATGGCACGGCGGTTCCAGGAGGAGCTGGCCGCCTTCCTCTTCGAGTATGACACCCCCCGC ATGGTGCTGGTGCGTAATAAGAAGGTGGGCGTTATCTTCCGACTGATCCAGCTGGTGGTC CTGGTCTACGTCATCGGGTGGGTGTTTCTCTATGAGAAGGGCTACCAGACCTCGAGCGGC CTCATCAGCAGTGTCTCTGTGAAACTCAAGGGCCTGGCCGTGACCCAGCTCCCTGGCCTC GGCCCCCAGGTCTGGGATGTGGCTGACTACGTCTTCCCAGCCCAGGGGGACAACTCCTTC GTGGTCATGACCAATTTCATCGTGACCCCGAAGCAGACTCAAGGCTACTGCGCAGAGCAC CCAGAAGGGGGCATATGCAAGGAAGACAGTGGCTGTACCCCTGGGAAGGCCAAGAGGAAG GCCCAAGGCATCCGCACGGGCAAGTGTGTGGCCTTCAACGACACTGTGAAGACGTGTGAG ATCTTTGGCTGGTGCCCCGTGGAGGTGGATGACGACATCCCGCGCCCTGCCCTTCTCCGA GAGGCCGAGAACTTCACTCTTTTCATCAAGAACAGCATCAGCTTTCCACGCTTCAAGGTC AACAGGCGCAACCTGGTGGAGGAGGTGAATGCTGCCCACATGAAGACCTGCCTCTTTCAC AAGACCCTGCACCCCCTGTGCCCAGTCTTCCAGCTTGGCTACGTGGTGCAAGAGTCAGGC CAGAACTTCAGCACCCTGGCTGAGAAGGGTGGAGTGGTTGGCATCACCATCGACTGGCAC TGTGACCTGGACTGGCACGTACGGCACTGCAGACCCATCTATGAGTTCCATGGGCTGTAC GAAGAGAAAAATCTCTCCCCAGGCTTCAACTTCAGGTTTGCCAGGCACTTTGTGGAGAAC GGGACCAACTACCGTCACCTCTTCAAGGTGTTTGGGATTCGCTTTGACATCCTGGTGGAC GGCAAGGCCGGGAAGTTTGACATCATCCCTACAATGACCACCATCGGCTCTGGAATTGGC ATCTTTGGGGTGGCCACAGTTCTCTGTGACCTGCTGCTGCTTCACATCCTGCCTAAGAGG CACTACTACAAGCAGAAGAAGTTCAAATACGCTGAGGACATGGGGCCAGGGGCGGCTGAG CGTGACCTCGCAGCTACCAGCTCCACCCTGGGCCTGCAGGAGAACATGAGGACATCCTGA Clone variation with respect to NM_002558.2 >OriGene 5' read for NM_002558 unedited
CAGAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACCAGGCCAAGAGC TGCTCTGATCACCCAGGGATTCTCTCTCCAACCCAAGTGCCTCCAGCTGACCTCTGGCTC CTGTCCTCTGGCTCCACCTGCACCGCCCTGCTCTTCCTAAGGGGCCAGGAAGCCCCCAGA AGCTCTACCATCGACGTGGGTGGTGGCACCCGGCTCACCCTGAGAGCAGAGGCCGTGCAG GGGGCTCAGTTCTGAGCCCCAGCCGGCCCACCATGGCACGGCGGTTCCAGGAGGAGCTGG CCGCCTTCCTCTTCGAGTATGACACCCCCCGCATGGTGCTGGTGCGTAATAAGAAGGTGG GCGTTATCTTCCGACTGATCCAGCTGGTGGTCCTGGTCTACGTCATCGGGTGGGGTGTTT CTCTATGAGAAGGGCTACCAGACCTCGAGCGGCCTCATCAGCAGTGTCTCTGTGAAACTC AAGGGGCCTGGCCGTGACCCAGCTCCCTGGCCTCGGCCCCCANGTCTGGGGATGGTGGCT GACTACGTCTTCCCAGCCCAGGGGGACAACTCCTNTCGTGGTCATGACCAATTTCATCGT GACCCCGAAGCAGACTCAAGGCTACTGCGCAGAGCACCCCANAAGGGGGCATATGCAAGG AAGACAGTGGCTGTACCCCTGNGAAGGCCAGNAGGAAGGCCCAAGGCATCCGCCGGGCAA GTTGTGTGGCCTTCACGACACTGTGGAGACGTGTGAGATCTTTGGCTGTGCCCCGTNGNA GGTGGATGACGACATCCCGCGCCCTGCCCTTCTCCGAGAGGCCGAGAAACTCACTCTTTT CATCAAGACAGCATCAGCTTTCCACGCTTCAAGTCAACAGCGCACCTGGGGAAGGAGGGG AATGCTGGCCAATGAAGACTGCCTTTTTACAAGACCTGCACCCCTGTGCCAGCCTTCACT TGGCTACGTGGGCCAGAGTCAGCCAAACTCACACCTGTCGGAA >OriGene 3' read for NM_002558 unedited
CGGGGGGGAACAGACCAGACNTCCTTCCNNNCNCCGTCAATCGTAGNACCNCGGNNCCGC ATTTTANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTGGGCCCAATCCCTTTATTGGACCCCACCCCTCGGTTTCCCCAAAACTTTTGTTT AAAAAAAACCAGGCAGGCCTTGGGAGCTGGGGGTGAACCACAGGCAGGGGGCCCAAGATT TGGGTGGGGGTCCCACCCCAACCCCAGGGAGCTGAGTAAGGGTTTATGGGTGGGAGGGGT GTCCTGGCCTGGCACACTTGGAAAAAAACCTTTTCCTTTGGGGGGGACATGGGCCCGACC ATGTGGGGGGGCTTGGGGGGGGAAAAGTGGGTAAAAGGGTGGGTTTGCAGGGCCCAAACT GTTCACATACACAATGGGGAAGGAAGCCTGGTGCATTTAAGGGGGGGGTACAACGGGGTG GGGGCATGAAAAACTGGGGGGGACGTGAGCACCCAAAACACATGCTGAAGGGGGTTGAGA ACCTGTTCAATGGTTGTCCCTTAACAGGAAATGGCGGGCTCAGGGTTAATCTGACCCCCC CTTAAGGGCCTTAAATCAAAAAGTTCGAGGACGGCCCTTTTTAAAATTAAGCCCCCAAAG GCCCGGGGGGGTTGGCCATTCACCACAAAAAAACGGGCACCCCTTGGAACTTTTGGGTTA GGAAGGCTGGGGGGGGGGCCCCACGAGACTTGCGATTTGCCAAAAAATTTCCCCCAGGGG AAACCCAAGGGGCACGGAAAAAACAAGGGCTTTAAAACAGGGCGTGGTTTAATAAAAAAA CTTTTTTTGTAAAAAGAGAAAAAGCNCCCCAGACTCGTTCACCATGTGGGGCCCACTCAC CCCCCCCTTTATTTCTCGGCCCTTGAAAATGGGGTTTTTCTCCCCCGAGGAAAAGAAATT TGGGGGTCCCTTTTTATTTTATTTCACGTTAAATTTAACCCCCCTGGGGTTATGCGCGGC CCCACGCGGAG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_002558 |
| Insert Size | 1200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002558.2, NP_002549.1 |
| RefSeq Size | 2910 bp |
| RefSeq ORF | 1200 bp |
| Locus ID | 5023 |
| UniProt ID | P51575 |
| Domains | P2X_receptor |
| Protein Families | Druggable Genome, Ion Channels: ATP Receptors, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
| Gene Summary | The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse
,Tobias Woehrle, Linda Yip, Abdallah Elkhal, Yuka Sumi, Yu Chen, Yongli Yao, Paul A. Insel, and Wolfgang G. Junger,
Blood, Nov 2010; 116: 3475 - 3484
[P2RX1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207924 | P2RX1 (Myc-DDK-tagged)-Human purinergic receptor P2X, ligand-gated ion channel, 1 (P2RX1) |
CNY 3,656.00 |
|
| RC207924L3 | Lenti-ORF clone of P2RX1 (Myc-DDK-tagged)-Human purinergic receptor P2X, ligand-gated ion channel, 1 (P2RX1) |
CNY 5,890.00 |
|
| RC207924L4 | Lenti-ORF clone of P2RX1 (mGFP-tagged)-Human purinergic receptor P2X, ligand-gated ion channel, 1 (P2RX1) |
CNY 5,890.00 |
|
| RG207924 | P2RX1 (tGFP-tagged) - Human purinergic receptor P2X, ligand-gated ion channel, 1 (P2RX1) |
CNY 5,256.00 |
