United States
Germany
Japan
United Kingdom
China
DNA Polymerase gamma (POLG) (NM_002693) Human Untagged Clone
CAT＃: SC118521
POLG (untagged)-Human polymerase (DNA directed), gamma (POLG), transcript variant 1
CNY 8,632.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002693, the custom clone sequence may differ by one or more nucleotides
ATGAGCCGCCTGCTCTGGAGGAAGGTGGCCGGCGCCACCGTCGGGCCAGGGCCGGTTCCAGCTCCGGGGC GCTGGGTCTCCAGCTCCGTCCCCGCGTCCGACCCCAGCGACGGGCAGCGGCGGCGGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCAACAGCAGCCTCAGCAGCCGCAAGTGCTATCCTCGGAGGGCGGGCAGCTGCGG CACAACCCATTGGACATCCAGATGCTCTCGAGAGGGCTGCACGAGCAAATCTTCGGGCAAGGAGGGGAGA TGCCTGGCGAGGCCGCGGTGCGCCGCAGCGTCGAGCACCTGCAGAAGCACGGGCTCTGGGGGCAGCCAGC CGTGCCCTTGCCCGACGTGGAGCTGCGCCTGCCGCCCCTCTACGGGGACAACCTGGACCAGCACTTCCGC CTCCTGGCCCAGAAGCAGAGCCTGCCCTACCTGGAGGCGGCCAACTTGCTGTTGCAGGCCCAGCTGCCCC CGAAGCCCCCGGCTTGGGCCTGGGCGGAGGGCTGGACCCGGTACGGCCCCGAGGGGGAGGCCGTACCCGT GGCCATCCCCGAGGAGCGGGCCCTGGTGTTCGACGTGGAGGTCTGCTTGGCAGAGGGAACTTGCCCCACA TTGGCGGTGGCCATATCCCCCTCGGCCTGGTATTCCTGGTGCAGCCAGCGGCTGGTGGAAGAGCGTTACT CTTGGACCAGCCAGCTGTCGCCGGCTGACCTCATCCCCCTGGAGGTCCCTACTGGTGCCAGCAGCCCCAC CCAGAGAGACTGGCAGGAGCAGTTAGTGGTGGGGCACAATGTTTCCTTTGACCGAGCTCATATCAGGGAG CAGTACCTGATCCAGGGTTCCCGCATGCGTTTCCTGGACACCATGAGCATGCACATGGCCATCTCAGGGC TAAGCAGCTTCCAGCGCAGTCTGTGGATAGCAGCCAAGCAGGGCAAACACAAGGTCCAGCCCCCCACAAA GCAAGGCCAGAAGTCCCAGAGGAAAGCCAGAAGAGGCCCAGCGATCTCATCCTGGGACTGGCTGGACATC AGCAGTGTCAACAGTCTGGCAGAGGTGCACAGACTTTATGTAGGGGGGCCTCCCTTAGAGAAGGAGCCTC GAGAACTGTTTGTGAAGGGCACCATGAAGGACATTCGTGAGAACTTCCAGGACCTGATGCAGTACTGTGC CCAGGACGTGTGGGCCACCCATGAGGTTTTCCAGCAGCAGCTACCGCTCTTCTTGGAGAGGTGTCCCCAC CCAGTGACTCTGGCCGGCATGCTGGAGATGGGTGTCTCCTACCTGCCTGTCAACCAGAACTGGGAGCGTT ACCTGGCAGAGGCACAGGGCACTTATGAGGAGCTCCAGCGGGAGATGAAGAAGTCGTTGATGGATCTGGC CAATGATGCCTGCCAGCTGCTCTCAGGAGAGAGGTACAAAGAAGACCCCTGGCTCTGGGACCTGGAGTGG GACCTGCAAGAATTTAAGCAGAAGAAAGCTAAGAAGGTGAAGAAGGAACCAGCCACAGCCAGCAAGTTGC CCATCGAGGGGGCTGGGGCCCCTGGTGATCCCATGGATCAGGAAGACCTCGGCCCCTGCAGTGAGGAGGA GGAGTTTCAACAAGATGTCATGGCCCGCGCCTGCTTGCAGAAGCTGAAGGGGACCACAGAGCTCCTGCCC AAGCGGCCCCAGCACCTTCCTGGACACCCTGGATGGTACCGGAAGCTCTGCCCCCGGCTAGACGACCCTG CATGGACCCCGGGCCCCAGCCTCCTCAGCCTGCAGATGCGGGTCACACCTAAACTCATGGCACTTACCTG GGATGGCTTCCCTCTGCACTACTCAGAGCGTCATGGCTGGGGCTACTTGGTGCCTGGGCGGCGGGACAAC CTGGCCAAGCTGCCGACAGGTACCACCCTGGAGTCAGCTGGGGTGGTCTGCCCCTACAGAGCCATCGAGT CCCTGTACAGGAAGCACTGTCTCGAACAGGGGAAGCAGCAGCTGATGCCCCAGGAGGCCGGCCTGGCGGA GGAGTTCCTGCTCACTGACAATAGTGCCATATGGCAAACGGTAGAAGAACTGGATTACTTAGAAGTGGAG GCTGAGGCCAAGATGGAGAACTTGCGAGCTGCAGTGCCAGGTCAACCCCTAGCTCTGACTGCCCGTGGTG GCCCCAAGGACACCCAGCCCAGCTATCACCATGGCAATGGACCTTACAACGACGTGGACATCCCTGGCTG CTGGTTTTTCAAGCTGCCTCACAAGGATGGTAATAGCTGTAATGTGGGAAGCCCCTTTGCCAAGGACTTC CTGCCCAAGATGGAGGATGGCACCCTGCAGGCTGGCCCAGGAGGTGCCAGTGGGCCCCGTGCTCTGGAAA TCAACAAAATGATTTCTTTCTGGAGGAACGCCCATAAACGTATCAGCTCCCAGATGGTGGTGTGGCTGCC CAGGTCAGCTCTGCCCCGTGCTGTGATCAGGCACCCCGACTATGATGAGGAAGGCCTCTATGGGGCCATC CTGCCCCAAGTGGTGACTGCCGGCACCATCACTCGCCGGGCTGTGGAGCCCACATGGCTCACCGCCAGCA ATGCCCGGCCTGACCGAGTAGGCAGTGAGTTGAAAGCCATGGTGCAGGCCCCACCTGGCTACACCCTTGT GGGTGCTGATGTGGACTCCCAAGAGCTGTGGATTGCAGCTGTGCTTGGAGACGCCCACTTTGCCGGCATG CATGGCTGCACAGCCTTTGGGTGGATGACACTGCAGGGCAGGAAGAGCAGGGGCACTGATCTACACAGTA AGACAGCCACTACTGTGGGCATCAGCCGTGAGCATGCCAAAATCTTCAACTACGGCCGCATCTATGGTGC TGGGCAGCCCTTTGCTGAGCGCTTACTAATGCAGTTTAACCACCGGCTCACACAGCAGGAGGCAGCTGAG AAGGCCCAGCAGATGTACGCTGCCACCAAGGGCCTCCGCTGGTATCGGCTGTCGGATGAGGGCGAGTGGC TGGTGAGGGAGTTGAACCTCCCAGTGGACAGGACTGAGGGTGGCTGGATTTCCCTGCAGGATCTGCGCAA GGTCCAGAGAGAAACTGCAAGGAAGTCACAGTGGAAGAAGTGGGAGGTGGTTGCTGAACGGGCATGGAAG GGGGGCACAGAGTCAGAAATGTTCAATAAGCTTGAGAGCATTGCTACGTCTGACATACCACGTACCCCGG TGCTGGGCTGCTGCATCAGCCGAGCCCTGGAGCCCTCGGCTGTCCAGGAAGAGTTTATGACCAGCCGTGT GAATTGGGTGGTACAGAGCTCTGCTGTTGACTACTTACACCTCATGCTTGTGGCCATGAAGTGGCTGTTT GAAGAGTTTGCCATAGATGGGCGCTTCTGCATCAGCATCCATGACGAGGTTCGCTACCTGGTGCGGGAGG AGGACCGCTACCGCGCTGCCCTGGCCTTGCAGATCACCAACCTCTTGACCAGGTGCATGTTTGCCTACAA GCTGGGTCTGAATGACTTGCCCCAGTCAGTCGCCTTTTTCAGTGCAGTCGATATTGACCGGTGCCTCAGG AAGGAAGTGACCATGGATTGTAAAACCCCTTCCAACCCAACTGGGATGGAAAGGAGATACGGGATTCCCC AGGGTGAAGCGCTGGATATTTACCAGATAATTGAACTCACCAAAGGCTCCTTGGAAAAACGAAGCCAGCC TGGACCATAG >OriGene 5' read for NM_002693 unedited
GTCAGCTTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGGAAGTTGCG GCTGCCAGCGAAGCGGACCGGCCGGGTGGAGGCCACACGCTACCCCGAGGCTGCGTAGGC CGCGCGAAGGGGGACGCCGTGCCGTGGGCCTGGGGTCGGGGGAGCAGCAGACCGGGAAGC ACCGATTTGGGGTGGAAGGCAGGCATGGTCAAACCCATTTCACTGACAGGAGAGCAGAGA CAGGACGTGTCTCTCTCCACGTCTTCCAGCCAGTAAAAGAAGCCAAGCTGGAGCCCAAAG CCAGGTGTTCTGACTCCCAGCGTGGGGGTCCCTGCACCAACCATGAGCCGCCTGCTCTGG AGGAAGGTGGCCGGCGCCACCGTCGGGCCAGGGCCGGTTCCAGCTCCGGGGCGCTGGGTC TCCAGCTCCGTCCCCGCGTCCGACCCCAGCGACGGGCAGCGGCGGCGGCAGCAGCAGCAG CAGCAGCAGCAGCAGCAGCAACAGCAGCCTCAGCAGCCGCAAGTGCTATCCTCGGAGGGC GGGCAGCTGCGGCACAACCCATTGGACATCCAGATGCTCTCGAGAGGGCTGCACGAGCAA ATCTTCGGGCAAGGGAGGGGAGATGCCTGGCGAGCNCGCGGTGCGCCGCAGCGTCGAGCA CCTGCAGAAGCACGGGCTCTGGNNGGCAGCCAGCCGTGCCCTTGCCCGACGTGGNAGCTG CGCCTGCCGCCCCTCTACGGNNGACACCTGGACCAGCACTTCCGCCTCCTGGCCCAGAAG CAGAGCCTGCCTACCTGGNAGCGGCAACTTGTGTGTTTGCAGGCCCAGCTGNCCCGAGCC CCCGCTTGCTGTNNNNNNNNNNNGNNTNTTTNCCCCCCCTGCCCNCCCGGGGGGGGGGGC CCCTCCCCGTGGCCTTCCCGGGGGACGGCCTTG >OriGene 3' read for NM_002693 unedited
ATGTACGCGGCCGCAATCTATATCGAGCTCTTTTTTTTTTTTTTTTTTTTTTTTCCTTCT TTTTATTTCCACTGCCTTGGAGCAGGTTTATCACGTTAAAGCATTAATTCTTTCCCCTTC TAGGGCACTGCATCAAAGCATGGGGGACAGAACAAAGAACCAGCCAAGAAGAAAAGGAAA AAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAA CAAGCAACAATGCCCCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACC CACTGAATTCAACTGCACCTTCAGTTAAAAGGAATCTTCTTGGCAGGTCCTGCTACTGAA AAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGATTTTGGG AGCCTGCACCACCCCGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTA TGGTCCAGGCTGGCTTAGTTTTTCCAAGGAGCCTTTGGCGAGTTCAATTATCTGGTAAAT ATCCAGCGCTTCACCCTGTGGAATCCCGTATCCTCTTTTCATCCCATTTGGGTTGGAAAG GGGTTTACAATCCATGGTCACTTCTTTCCTGAGGCACCGGTCAATTTAGACTGCCCCGCA AAAGGCCACTGACTTGGGCAAGTATTTCATACCAAGCTTGTAGGTAAACATGCACCTGGT ACATAAGGTTGTGTTCCCTGCATGCCCAGGCCATACTGTTCTTGCCCCCTCTCCCCCCCC ACTACCGTATCCTCCCCTGTTTGTTCAGCATCTACCCCTATTTTTGTTATACTCTTCTAT AGTCCCCTCTTCGATCACTACCCCGCCGGCCATTCCTTATAGGAACCACTCCGTACAACA GTATTTACAGCCTGTTATCTTCTTTAACTCCACATCCCACACCCTACCTCCTCCCGCGCC CCCTCTCTCACCCTCCGCGCTCATATAATTCACCCCCAAGTATCCTATCCAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002693 |
| Insert Size | 4110 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002693.1, NP_002684.1 |
| RefSeq Size | 4465 bp |
| RefSeq ORF | 3720 bp |
| Locus ID | 5428 |
| UniProt ID | P54098 |
| Domains | DNA_pol_A |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways |
| Gene Summary | Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204456 | POLG (Myc-DDK-tagged)-Human polymerase (DNA directed), gamma (POLG), transcript variant 1 |
CNY 8,624.00 |
|
| RC204456L1 | Lenti ORF clone of Human polymerase (DNA directed), gamma (POLG), transcript variant 1, Myc-DDK-tagged |
CNY 11,024.00 |
|
| RC204456L2 | Lenti ORF clone of Human polymerase (DNA directed), gamma (POLG), transcript variant 1, mGFP tagged |
CNY 12,540.00 |
|
| RC204456L3 | Lenti ORF clone of Human polymerase (DNA directed), gamma (POLG), transcript variant 1, Myc-DDK-tagged |
CNY 12,540.00 |
|
| RC204456L4 | Lenti ORF clone of Human polymerase (DNA directed), gamma (POLG), transcript variant 1, mGFP tagged |
CNY 11,024.00 |
|
| RG204456 | POLG (tGFP-tagged) - Human polymerase (DNA directed), gamma (POLG), transcript variant 1 |
CNY 8,624.00 |
其它DNA Polymerase gamma产品
