DNA Polymerase gamma (POLG) (NM_002693) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204456L4V

  • LentiORF®

Lenti ORF particles, POLG (mGFP-tagged) - Human polymerase (DNA directed), gamma (POLG), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 12,540.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name DNA Polymerase gamma (POLG) (NM_002693) Human Tagged ORF Clone Lentiviral Particle
Synonyms MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_002693
ORF Size 3717 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204456).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002693.1
RefSeq Size 4464 bp
RefSeq ORF 3720 bp
Locus ID 5428
Domains DNA_pol_A
Protein Families Druggable Genome
Protein Pathways Metabolic pathways
MW 139.6 kDa
Gene Summary Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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