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Serglycin (SRGN) (NM_002727) Human Untagged Clone
CAT＃: SC118445
SRGN (untagged)-Human serglycin (SRGN), transcript variant 1
CN¥ 1,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PPG; PRG; PRG1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118445 sequence for NM_002727 edited (data generated by NextGen Sequencing)
ATGATGCAGAAGCTACTCAAATGCAGTCGGCTTGTCCTGGCTCTTGCCCTCATCCTGGTT CTGGAATCCTCAGTTCAAGGTTATCCTACGCAGAGAGCCAGGTACCAATGGGTGCGCTGC AATCCAGACAGTAATTCTGCAAACTGCCTTGAAGAAAAAGGACCAATGTTCGAACTACTT CCAGGTGAATCCAACAAGATCCCCCGTCTGAGGACTGACCTTTTTCCAAAGACGAGAATC CAGGACTTGAATCGTATCTTCCCACTTTCTGAGGACTACTCTGGATCAGGCTTCGGCTCC GGCTCCGGCTCTGGATCAGGATCTGGGAGTGGCTTCCTAACGGAAATGGAACAGGATTAC CAACTAGTAGACGAAAGTGATGCTTTCCATGACAACCTTAGGTCTCTTGACAGGAATCTG CCCTCAGACAGCCAGGACTTGGGTCAACATGGATTAGAAGAGGATTTTATGTTATAA Clone variation with respect to NM_002727.2 92 g=>a >OriGene 5' read for NM_002727 unedited
AATTGTCAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGAGTTGGC GTGCAGCTGGGAGAGCTAGACTAAGTTGGTCATGATGCAGAAGCTACTCAAATGCAGTCG GCTTGTCCTGGCTCTTGCCCTCATCCTGGTTCTGGAATCCTCAGTTCAAGGTTATCCTAC GCAGAGAGCCAGGTACCAATGGGTGCGCTGCAATCCAGACAGTAATTCTGCAAACTGCCT TGAAGAAAAAGGACCAATGTTCGAACTACTTCCAGGTGAATCCAACAAGATCCCCCGTCT GAGGACTGACCTTTTTCCAAAGACGAGAATCCAGGACTTGAATCGTATCTTCCCACTTTC TGAGGACTACTCTGGATCAGGCTTCGGCTCCGGCTCCGGCTCTGGATCAGGATCTGGGAG TGGCTTCCTAACGGAAATGGAACAGGATTACCAACTAGTAGACGAAAGTGATGCTTTCCA TGACAACCTTAGGTCTCTTGACAGGAATCTGCCCTCAGACAGCCAGGACTTGGGTCAACA TGGATTAGAAGAGGATTTTATGTTATAAAAGAGGATTTTCCCACCTTGACACCAGGCAAT GTAGTTAGCATATTTTATGTACCATGGTTATATGATTAATCTTGGGACAAAGAATTTTAT AGAAATTTTTAAACATCTGAAAAAGAAGCTTAAGTTTTATCATCCTTTTTTTTCTCATGA ATTCTTAAAGGATTATGCTTTAATGCTGNTATCTATCTTATTGTTCTTGAAATACCTGCA TTTTTTGGTATCATGTTCAACCAACATCATTATGAAATTAATTAGATTCCCATGGCCATA AAATGGCTTTAAGAAATATATATATTTTTAAAGTAGCTTGAAAGCCAAATGGCAGGTATA TTT >OriGene 3' read for NM_002727 unedited
TTGCTGCTTNTATATATAGTAACATTTGGAAATACACANATATCCAGGNAAAAAAGGTAA AGCAGTATGAGGTATTGACAGCACAACTGTGTTTTAATTTGGGAGTTAATTTGGGGTGTT ATGTAACAGCAATCATACTTGTAGACAAACACATCCACTAGCTCTGCAAACACATTCAAA GGTAATAGTATATAGTACACTCCACCCTGTAAAATATGTCAAATACCCCCACTCTACAAA TTCACTGTGTTTCATTATTTTTTTTTTGTTTTTATAAGAAAAGGGGCATATCATTATAAT TCACAATCCAAGTCAGAGTCTTAATTTAGGTATGAAATATTACCTGCCAATTTGCTTCTC AAGCTACTTTAAAAATATATATATATTCTTTAAAGCCATTTTATGGCCATGGGAATCTAA TTAATTTCATAATGATGTTGGTTGAACATGATACCAAAAAATGCAGGTATTTTCAAGAAC AATAAGATAGATAACAGCATTAAAGCATAATCCTTTAAGAATTCATGAGAAAAAAAAGGA TGATAAAACTTAAGCTTCTTTTTCAGATGTTTAAAAATTTCTATAAAATTCTTTGTCCCA AGATTAATCATATAACCATGGTACATAAAATATGCTAACTACATTGCCTGGTGTCAAGGT GGGAAAATCCTCTTTTATAACATAAAATCCTCTTCTAATCCATGTTGACCCAAGTCCTGG CTGTCTGNAGGCAGATTCCTGTCAAGAGACCTAAGGTTGTCATGGAAAGCATCACTTTCG GCTACTAGNTGGTAATCCTGTTCCATTTTCGTTAGGAGCCACTCCCAGTCCTGACCANAG CCGAGCCGGAGCCGAAGCTGATCANNAGTAGTCTCAGAAGTGGGAAGATCGATTCAAGTC TGGATTTCGGCTTGGAAAAGGCAGTCCTCAACGGGGAACTGTTGGATCACTGNAAGAGTC GACATGGCCTTTTCTTAAGGGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002727 |
| Insert Size | 1270 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002727.2, NP_002718.2 |
| RefSeq Size | 1270 bp |
| RefSeq ORF | 477 bp |
| Locus ID | 5552 |
| UniProt ID | P10124 |
| Domains | Serglycin |
| Gene Summary | This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010] Transcript Variant: This variant (1) lacks an exon in the 5' UTR compared to variant 2. Both variants 1 and 3 encode isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202118 | SRGN (Myc-DDK-tagged)-Human serglycin (SRGN), transcript variant 1 |
CN¥ 1,800.00 |
|
| RC202118L1 | Lenti ORF clone of Human serglycin (SRGN), transcript variant 1, Myc-DDK-tagged |
CN¥ 4,200.00 |
|
| RC202118L2 | Lenti ORF clone of Human serglycin (SRGN), transcript variant 1, mGFP tagged |
CN¥ 4,200.00 |
|
| RC202118L3 | Lenti ORF clone of Human serglycin (SRGN), transcript variant 1, Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC202118L4 | Lenti ORF clone of Human serglycin (SRGN), transcript variant 1, mGFP tagged |
CN¥ 4,200.00 |
|
| RG202118 | SRGN (tGFP-tagged) - Human serglycin (SRGN), transcript variant 1 |
CN¥ 3,400.00 |
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