SAFB (NM_002967) Human Untagged Clone
CAT#: SC118304
SAFB (untagged)-Human scaffold attachment factor B (SAFB), transcript variant 3
CNY 6,712.00
CNY 7,220.00
Product images
CNY 6,281.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HAP; HET; SAB-B1; SAF-B; SAF-B1; SAFB1 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_002967, the custom clone sequence may differ by one or more nucleotides
ATGGCGGAGACTCTGTCAGGCCTAGGTGATTCTGGAGCGGCGGGCGCGGCGGCTCTGAGCTCCGCCTCGT CAGAGACCGGGACGCGGCGCCTCAGCGACCTGCGAGTGATCGATCTGCGGGCGGAGCTGAGGAAACGGAA TGTGGACTCGAGCGGCAACAAGAGCGTTTTGATGGAGCGGCTGAAGAAGGCAATTGAAGATGAAGGTGGT AATCCTGACGAAATTGAAATTACCTCCGAGGGAAACAAGAAAACATCAAAGAGGTCTAGCAAAGGGCGCA AACCAGAAGAAGAGGGTGTGGAAGATAACGGGCTGGAGGAAAACTCTGGGGATGGACAGGAGGATGTTGA GACCAGTCTGGAGAACTTGCAGGACATCGACATCATGGATATCAGTGTGTTGGATGAAGCAGAAATTGAT AATGGAAGCGTTGCAGATTGTGTCGAAGACGATGATGCTGATAACCTCCAGGAGTCCCTGTCGGATAGTA GAGAGCTAGTCGAGGGGGAAATGAAAGAGCTTCCGGAGCAGCTTCAGGAACATGCTATAGAGGACAAAGA AACTATAAACAATTTAGATACTTCATCATCTGACTTCACTATATTACAGGAAATTGAAGAGCCATCCCTG GAGCCAGAAAATGAGAAAATACTCGACATTTTGGGGGAAACTTGTAAATCTGAGCCAGTAAAAGAAGAAA GTTCCGAGCTGGAGCAGCCATTTGCACAGGACACAAGTAGCGTGGGGCCAGACAGAAAGCTTGCGGAGGA AGAGGACCTATTTGACAGCGCCCATCCGGAAGAGGGTGATTTAGATTTGGCCAGCGAGTCAACAGCACAC GCTCAGTCGAGCAAGGCAGACAGCCTGTTAGCGGTAGTGAAAAGGGAGCCCGCGGAGCAGCCAGGCGATG GCGAGAGGACGGACTGTGAGCCTGTAGGGCTAGAGCCGGCAGTTGAGCAGAGTAGTGCGGCCTCCGAGCT CGCGGAGGCCTCTAGCGAGGAGCTCGCAGAAGCACCCACGGAAGCCCCAAGCCCAGAAGCCAGAGATAGC AAAGAAGACGGGAGGAAGTTTGATTTTGACGCTTGTAATGAAGTCCCTCCGGCTCCTAAAGAGTCCTCAA CCAGTGAGGGCGCTGATCAGAAAATGAGTTCTCCCGAAGATGACTCGGATACAAAAAGGCTTTCCAAAGA GGAAAAGGGTCGCAGCAGTTGTGGTAGAAATTTCTGGGTTAGTGGACTCTCTTCTACAACCAGAGCTACA GATTTGAAGAATCTTTTCAGCAAATATGGGAAGGTGGTGGGCGCCAAGGTTGTGACAAATGCCCGGAGTC CTGGAGCTCGCTGTTACGGTTTTGTCACGATGTCCACAGCAGAAGAGGCCACAAAATGCATTAACCACCT GCACAAGACGGAGCTCCACGGAAAGATGATCTCCGTGGAGAAAGCCAAAAATGAACCTGTGGGAAAGAAA ACCTCTGACAAAAGAGACAGTGACGGGAAAAAGGAGAAGTCGAGCAACAGTGACAGATCTACAAACCTTA AGAGGGATGATAAATGTGACAGAAAAGATGATGCTAAGAAGGGTGACGACGGAAGTGGAGAAAAGAGTAA GGACCAAGATGATCAGAAACCTGGCCCCTCAGAGCGATCTCGAGCCACAAAGTCAGGAAGTCGAGGGACC GAACGGACTGTAGTAATGGATAAATCCAAAGGGGTGCCTGTGATTAGTGTAAAAACGTCCGGGTCCAAAG AGAGAGCTTCCAAAAGCCAGGATCGCAAATCAGCCAGCAGAGAGAAGCGGTCCGTCGTGTCCTTTGATAA GGTCAAGGAGCCTCGGAAGTCAAGAGACTCAGAGTCCCATAGCAGGGTGCGTGAACGCAGTGAACGCGAA CAACGCATGCAGGCGCAGTGGGAGCGCGAGGAGCGTGAGCGGCTGGAGATTGCCCGAGAGAGGCTGGCCT TCCAGCGCCAGCGGCTGGAGCGGGAGCGCATGGAGCGGGAACGGCTGGAGCGCGAACGCATGCACGTGGA GCACGAGCGCAGGCGCGAGCAGGAGCGCATCCACCGTGAGCGCGAGGAGCTGAGGCGCCAGCAGGAACTG CGCTATGAGCAGGAGCGGCGGCCCGCGGTGCGGCGGCCCTACGACCTGGACCGGCGAGATGATGCCTATT GGCCGGAAGCCAAGCGGGCCGCCCTGGATGAGCGCTACCATTCTGACTTTAACCGCCAGGACCGCTTCCA CGACTTTGACCACAGGGACCGCGGCCGCTACCCCGACCACTCGGTGGACAGGAGAGAAGGTTCAAGGTCA ATGATGGGAGAACGAGAAGGACAGCATTACCCAGAACGCCATGGAGGACCAGAGCGCCACGGCCGGGACT CCCGCGATGGCTGGGGGGGCTATGGCTCTGACAAGAGGATGAGCGAGGGCCGGGGGCTGCCTCCTCCCCC CAGACGTGACTGGGGGGACCATGGCCGAAGAGAGGATGACCGGTCATGGCAGGGCACGGCCGACGGGGGC ATGATGGACAGGGATCACAAGAGGTGGCAAGGTGGCGAGAGAAGCATGTCCGGTCACTCCGGGCCTGGCC ACATGATGAACCGAGGAGGAATGTCAGGGCGCGGCAGCTTTGCCCCAGGCGGGGCCTCCCGGGGCCACCC CATCCCACACGGTGGCATGCAGGGCGGGTTTGGAGGCCAGAGCCGGGGGAGCAGGCCCAGCGATGCCCGC TTCACTCGCCGCTACTGA >OriGene 5' read for NM_002967 unedited
GTGTGCAAATTTATGTATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGGCG ACTGGAGCGGTTCCCTCGCAGGCGGCGCCATTTTGTGCTAGGAGCCTGATAAAACCGGCC CGGTTCTGTGGAAAGTGGGCGGCGGAGCCAGGGTCCCTGGAATGGCGGAGACTCTGTCAG GCCTAGGTGATTCTGGAGCGGCGGGCGCGGCGGCTCTGAGCTCCGCCTCGTCAGAGACCG GGACGCGGCGCCTCAGCGACCTGCGAGTGATCGATCTGCGGGCGGAGCTGAGGAAACGGA ATGTGGACTCGAGCGGCAACAAGAGCGTTTTGATGGAGCGGCTGAAGAAGGCAATTGAAG ATGAAGGTGGTAATCCTGACGAAATTGAAATTACCTCCGAGGGAAACAAGAAAACATCAA AGAGGTCTAGCAAAGGGCGCAAACCAGAAGAAGAGGGTGTGGAAGATAACGGGCTGGAGG AAAACTCTGGGGATGGACAGGAGGATGTTGAGACCAGTCTGGAGAACTTGCAGGACATCG ACATCATGGATATCAGTGTGTTGGATGAAGCAGAAATTGATAATGGAAGCGTTGCAGATT GTGTCGAAGACGATGATGCTGATAACCTCCAGGAGTCCCTGTCGGATAGTAGAGAGCTAG TCGAGGGGGAAATGAAAGAGCTTTCGGAGCAGCTTCAGGAACATGCTATAGAGGACAAAG AAACTATTAACAATNTAAATACTTCATCATCTGACTTCACTATATTACAGGAAATTGAAA GACCCTTCCCTGGAGCCCAGTTCTCCCCGAGAAGACTTCGGATACAAAAAGGCTTTCCAA GAGGGAAAGGGTCGCACCAGTTTGGGTAAAAATTTCTGGGTTAGTGAACTCTTTCTTACA CCAGAGCTACAGATTTGAAGATACTTTCC >OriGene 3' read for NM_002967 unedited
GACCGGGCCGCCTTCTATATCGAGTTTTTTTTTTTTTTTTTTATGTGAACGGAACACATT TATTACAAAAAAAAAAAACCCCAAAACGAAAAACAAATTCACATTGTATTGAGCTACAAT ATGGCAGCAGATTAAAAAAAAATATTTTTACACAGTTTAAGGTAACTCCTAACAGAACAT AGCCTTGTTGCCACGAGACAGGACACAGGATTCCAAGTACTCAGTAGCGGCGAGTGAAGC GGGCATCGCTGGGCCTGCTCCCCCGGCTCTGGCCTCCAAACCCGCCCTGCATGCCACCGT GTGGGATGGGGTGGCCCCGGGAGGCCCCGCCTGGGGCAAAGCTGCCGCGCCCTGACATTC CTCCTCGGTTCATCATGTGGCCAGGCCCGGAGTGACCGGACATGCTTCTCTCGCCACCTT GCCACCTCTTGTGATCCCTGTCCATCATGCCCCCGTCGGCCGTGCCCTGCCATGACCGGT CATTCTCTCTTCGGCCATGGTCCCCCCAGTCACGTCTGCCCCTGGGGGGAGGAGGCAGTC CCCGGACCTCGCTCATCCTCTTGTTAGAGCCATAGCCCTCCCATTCATTGTGGGAGATCC GGTCGTGGTGCTTTGGTTCTCCATGGACGTTCTGGGTAATGGCTGGACTTCATTGTCTTT CATCTTTTGCCCTTGAACCCTTCTCTACTGACACCTCGTACTGGCATGGGCACATCGATC GACGCTCCTTGGTGTGTCTAACATACCGGTATACGGTCTTTGGCCGGTCTTTCGTTCTAT TTGGACTACTACTCTTTCTGGCGCGTTTCCATCGGTCTCCCGTTCTCTTCGTTTTTTTTC TCTCGTCCTTTTTCATCTCGTCGTCTTTTCTCATGTATCCCCATTACCACATTGATCATT AATCTCCACTCACCGTATTGCTCTCCCTCACTAAACTTCTTCTCTTTCATTTAAATCTTC TCCTGAATTCACTCCGTTGTTTCTTTTTCTTTTCGTCAATTCCTGCCACGCCTCTCCTGC TTCTCTCTCTCCGCTGGTCATATTGCTT |
Restriction Sites | NotI-NotI |
ACCN | NM_002967 |
Insert Size | 2630 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002967.2, NP_002958.2 |
RefSeq Size | 3115 bp |
RefSeq ORF | 2748 bp |
Locus ID | 6294 |
UniProt ID | Q15424 |
Domains | RRM, SAP |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011] Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 3) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC215199 | SAFB (Myc-DDK-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3. Note: ORF is codon optimized |
CNY 10,048.00 |
|
RC215199L3 | Lenti-ORF clone of SAFB (Myc-DDK-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3. Note: ORF is codon optimized |
CNY 9,030.00 |
|
RC215199L4 | Lenti-ORF clone of SAFB (mGFP-tagged)-Human scaffold attachment factor B (SAFB), transcript variant 3. Note: ORF is codon optimized |
CNY 12,448.00 |
|
RG215199 | SAFB (tGFP-tagged) - Human scaffold attachment factor B (SAFB), transcript variant 3 |
CNY 11,648.00 |