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SLC10A1 (NM_003049) Human Untagged Clone
CAT＃: SC118232
SLC10A1 (untagged)-Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1)
CNY 5,488.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FHCA2; NTCP |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118232 sequence for NM_003049 edited (data generated by NextGen Sequencing)
ATGGAGGCCCACAACGCGTCTGCCCCATTCAACTTCACCCTGCCACCCAACTTTGGCAAG CGCCCCACAGACCTGGCACTGAGCGTCATCCTGGTGTTCATGTTGTTCTTCATCATGCTC TCGCTGGGCTGCACCATGGAGTTCAGCAAGATCAAGGCTCACTTATGGAAGCCTAAAGGG CTGGCCATCGCCCTGGTGGCACAGTATGGCATCATGCCCCTCACAGCCTTTGTGCTGGGC AAGGTCTTCCGGCTGAAGAACATTGAGGCACTGGCCATCTTGGTCTGTGGCTGCTCACCT GGAGGGAACCTGTCCAATGTCTTCAGTCTGGCCATGAAGGGGGACATGAACCTCAGCATT GTGATGACCACCTGCTCCACCTTCTGTGCCCTTGGCATGATGCCTCTCCTCCTGTACATC TACTCCAGGGGGATCTATGATGGGGACCTGAAGGACAAGGTGCCCTATAAAGGCATCGTG ATATCACTGGTCCTGGTTCTCATTCCTTGCACCATAGGGATCGTCCTCAAATCCAAACGG CCACAATACATGCGCTATGTCATCAAGGGAGGGATGATCATCATTCTCTTGTGCAGTGTG GCCGTCACAGTTCTCTCTGCCATCAATGTGGGGAAGAGCATCATGTTTGCCATGACACCA CTCTTGATTGCCACCTCCTCCCTGATGCCTTTTATTGGCTTTCTGCTGGGTTATGTTCTC TCTGCTCTCTTCTGCCTCAATGGACGGTGCAGACGCACTGTCAGCATGGAGACTGGATGC CAAAATGTCCAACTCTGTTCCACCATCCTCAATGTGGCCTTTCCACCTGAAGTCATTGGA CCACTTTTCTTCTTTCCCCTCCTCTACATGATTTTCCAGCTTGGAGAAGGGCTTCTCCTC ATTGCCATATTTTGGTGCTATGAGAAATTCAAGACTCCCAAGGATAAAACAAAAATGATC TACACAGCTGCCACAACTGAAGAAACAATTCCAGGAGCTCTGGGAAATGGCACCTACAAA GGGGAGGACTGCTCCCCTTGCACAGCCTAG Clone variation with respect to NM_003049.3 225 g=>a >OriGene 5' read for NM_003049 unedited
CCCCCCGCCGCNACANCCNCCCCTACCCNNNCCNGGGGTTTCGNNATTTGTNATACGACT TACTATAGGGCGGCCGCGCATTCGGCACGAGCTCTGTCCTGAGNAGTGATTAAAGAAGGC ATCCAGCAAGAACTGCACAAGAAACGGAGTCAGCCGGAGAACAAGGAGTGGTCTTCCACT GCCTCACAGGAGGATGGAGGCCCACAACGCGTCTGCCCCATTCAACTTCACCCTGCCACC CAACTTTGGCAAGCGCCCCACAGACCTGGCACTGAGCGTCATCCTGGTGTTCATGTTGTT CTTCATCATGCTCTCGCTGGGCTGCACCATGGAGTTCAGCAAGATCAAGGCTCACTTATG GAAGCCTAAAGGGCTGGCCATCGCCCTGGTGGCACAGTATGGCATCATGCCCCTCACAGC CTTTGTGCTGGGCAAGGTCTTCCGGCTGAAGAACATTGAGGCACTGGCCATCTTGGTCTG TGGCTGCTCACCTGGAGGGAACCTGTCCAATGTCTTCAGTCTGGCCATGAAGGGGGACAT GAACCTCAGCATTGTGATGACCACCTGCTCCACCTTCTGTGCCCTTGGCATGATGCCTCT CCTCCTGTACATCTACTCCAGGGGGATCTATGATGGGGACCTGAAGGACAAGGTGCCCTA TAAAGGCATCGTGATATCACTGGTCCTGGTTCTCATTCCTTGCACCATAGGGATCGTCCT CAAATCCAAACGGCCACAATACATGCGCTATGTCATCAAGGGAAGGATGATCATCATTCT CTTGTGCAGTGTGGCCGTCACAGTTCTCTCTGCCATCAAATGTGGGGAAGAGCATCATGT TTGCCATGACACCACTCTTGATTGCCACCTCCTCCCTGATGCCTTNTATNGNCTNTCTGC CTGGGTAATGTCTCTCTGCTCTCTTCTGCCTCAATGGACGGTG >OriGene 3' read for NM_003049 unedited
ACTTGNACCCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTTTAGGTTAGAAC TTCTGAAGTTTAATTCTACAGGAGTTGTGAGCATTTATTTCTCTTTTGGGTCACAAAACT TGGAATGGGATTTGGGTATTTGAGTAATGGGTTAAACATATATATTGATTAGTTCAGGAA TTGAGTGACTTTAAGATGCTTATCAGACACTTTTAGAGATCCCAGCAAGAGGCAGATTCG GTTTCTGGTTTCATAGAGTTTACAGTCACTGAACAAGTCTTTAAAATAAGTAGCAAATTC TAAGTTGGGGATAGGTGAGGCTTCTTGGGTAGACACCCTGTCTGTGTTCCCGGCCAAGAC TTGATGATTCTGATAGATGTACTGGAAATGCTGGAGAAAGACTCANNGCAGACTGGTGTT TTTGCTGCTCTCTCTAGTTACCACACTGGCTTTCAGAAATGCTTTGGGACCAGAATCCAN GCCACCCAGGGGAGGGCTAGGCTGTGCAAGGGGAGCAGTCCTCCCCTTGGAGGTGCCATT TCCCAAAGCTCCTGGAAATTGTTCTTCATTTGGGGCACCTGGGTAGATCATTTTTGTTTT ATCCTTGGAATCTGAATTTTTCATACCCCAAATTTTGCATTGGGAAAAGCCTTTTTCAGC TGGAAAATCTTTAAAGGAGGGAAAAAAAAAAAGGTCCATGACCTTGGGGGAAAGGCCCTT TAGTTGGGGGAAAAAATGGACTTTTTGGTTCCAATTCTATTTGAAAAGGGTTTCCCCCCC TTTGGGCCAAAAAACCAAAACTTACCCCCCAAACCCTAAAGGTTTGGGGGGGGGGACAAA AAATGTGTTGGTAAAAAAAAGTCTTCCCCTTTTTGGGAAAAAACTCTCCGCCCCCTCCAA AAAAAGTAACATCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003049 |
| Insert Size | 1750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003049.1, NP_003040.1 |
| RefSeq Size | 1580 bp |
| RefSeq ORF | 1050 bp |
| Locus ID | 6554 |
| UniProt ID | Q14973 |
| Domains | SBF |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways
,null,
PLoS Pathogens
,PubMed ID 28945802
[SLC10A1]
|
|
(-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes
,Huang, HC;Tao, MH;Hung, TM;Chen, JC;Lin, ZJ;Huang, C;,
Antiviral Res.
,PubMed ID 25260897
[SLC10A1]
|
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Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of the bile acid metabolism
,Oehler, N;Volz, T;Bhadra, OD;Kah, J;Allweiss, L;Giersch, K;Bierwolf, J;Riecken, K;Pollok, JM;Lohse, AW;Fehse, B;Petersen, J;Urban, S;Lütgehetmann, M;Heeren, J;Dandri, M;,
Hepatology. April 2014
,PubMed ID 24711282
[SLC10A1]
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Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-specific Entry into Hepatocytes
,Ni, Y;Lempp, FA;Mehrle, S;Nkongolo, S;Kaufman, C;Fälth, M;Stindt, J;Königer, C;Nassal, M;Kubitz, R;Sültmann, H;Urban, S;,
Gastroenterology Dec 2013.
,PubMed ID 24361467
[SLC10A1]
|
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Activation of Nrf2 by Toxic Bile Acids Provokes Adaptive Defense Responses to Enhance Cell Survival at the Emergence of Oxidative Stress
,Kah Poh Tan, Mingdong Yang, and Shinya Ito,
Mol Pharmacol. 2007 Nov;72(5):1380-90.
[SLC10A1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210241 | SLC10A1 (Myc-DDK-tagged)-Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1) |
CNY 5,488.00 |
|
| RC210241L1 | Lenti ORF clone of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210241L2 | Lenti ORF clone of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1), mGFP tagged |
CNY 7,888.00 |
|
| RC210241L3 | Lenti ORF clone of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210241L4 | Lenti ORF clone of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1), mGFP tagged |
CNY 7,888.00 |
|
| RG210241 | SLC10A1 (tGFP-tagged) - Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (SLC10A1) |
CNY 7,088.00 |
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