Solute carrier family 22 member 5 (SLC22A5) (NM_003060) Human Untagged Clone
CAT#: SC118201
SLC22A5 (untagged)-Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5)
CNY 4,152.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CDSP; OCTN2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC118201 sequence for NM_003060 edited (data generated by NextGen Sequencing)
ATGCGGGACTACGACGAGGTGACCGCCTTCCTGGGCGAGTGGGGGCCCTTCCAGCGCCTC ATCTTCTTCCTGCTCAGCGCCAGCATCATCCCCAATGGCTTCACCGGCCTGTCCTCCGTG TTCCTGATAGCGACCCCGGAGCACCGCTGCCGGGTGCCGGACGCCGCGAACCTGAGCAGC GCCTGGCGCAACCACACTGTCCCACTGCGGCTGCGGGACGGCCGCGAGGTGCCCCACAGC TGCCGCCGCTACCGGCTCGCCACCATCGCCAACTTCTCGGCGCTCGGGCTGGAGCCGGGG CGCGACGTGGACCTGGGGCAGCTGGAGCAGGAGAGCTGTCTGGATGGCTGGGAGTTCAGT CAGGACGTCTACCTGTCCACCATTGTGACCGAGTGGAACCTGGTGTGTGAGGACGACTGG AAGGCCCCACTCACAATCTCCTTGTTCTTCGTGGGTGTGCTGTTGGGCTCCTTCATTTCA GGGCAGCTGTCAGACAGGTTTGGCCGGAAGAATGTGCTGTTCGTGACCATGGGCATGCAG ACAGGCTTCAGCTTCCTGCAGATCTTCTCGAAGAATTTTGAGATGTTTGTCGTGCTGTTT GTCCTTGTAGGCATGGGCCAGATCTCCAACTATGTGGCAGCATTTGTCCTGGGGACAGAA ATTCTTGGCAAGTCAGTTCGTATAATATTCTCTACGTTAGGAGTGTGCATATTTTATGCA TTTGGCTACATGGTGCTGCCACTGTTTGCTTACTTCATCCGAGACTGGCGGATGCTGCTG GTGGCGCTGACGATGCCGGGGGTGCTGTGCGTGGCACTCTGGTGGTTCATCCCTGAGTCC CCCCGATGGCTCATCTCTCAGGGACGATTTGAAGAGGCAGAGGTGATCATCCGCAAGGCT GCCAAAGCCAATGGGATTGTTGTGCCTTCCACTATCTTTGACCCGAGTGAGTTACAAGAC CTAAGTTCCAAGAAGCAGCAGTCCCACAACATTCTGGATCTGCTTCGAACCTGGAATATC CGGATGGTCACCATCATGTCCATAATGCTGTGGATGACCATATCAGTGGGCTATTTTGGG CTTTCGCTTGATACTCCTAACTTGCATGGGGACATCTTTGTGAACTGCTTCCTTTCAGCG ATGGTTGAAGTCCCAGCATATGTGTTGGCCTGGCTGCTGCTGCAATATTTGCCCCGGCGC TATTCCATGGCCACTGCCCTCTTCCTGGGTGGCAGTGTCCTTCTCTTCATGCAGCTGGTA CCCCCAGACTTGTATTATTTGGCTACAGTCCTGGTGATGGTGGGCAAGTTTGGAGTCACG GCTGCCTTTTCCATGGTCTACGTGTACACAGCCGAGCTGTATCCCACAGTGGTGAGAAAC ATGGGTGTGGGAGTCAGCTCCACAGCATCCCGCCTGGGCAGCATCCTGTCTCCCTACTTC GTTTACCTTGGTGCCTACGACCGCTTCCTGCCCTACATTCTCATGGGAAGTCTGACCATC CTGACAGCCATCCTCACCTTGTTTCTCCCAGAGAGCTTCGGTACCCCACTCCCAGACACC ATTGACCAGATGCTAAGAGTCAAAGGAATGAAACACAGAAAAACTCCAAGTCACACAAGG ATGTTAAAAGATGGTCAAGAAAGGCCCACAATCCTTAAAAGCACAGCCTTCTAA Clone variation with respect to NM_003060.3 285 t=>c;807 a=>g >OriGene 5' read for NM_003060 unedited
AAGTCAAATATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCAGCCG CGGCAGGACCAAGGCGGCGGTGTCAGCTCGCGAGCCTACCCTCCGCGGACGGTCTTGGGT CGCCTGCTGCCTGGCTTGCCTGGTCGGCGGCGGGTGCCCCGCGCGCACGCGCAAAGCCCG CCGCGTTCCCCGACCCCAGGCCGCGCTCTGTGGGCCTCTGAGGGCGGCATGCGGGACTAC GACGAGGTGACCGCCTTCCTGGGCGAGTGGGGGCCCTTCCAGCGCCTCATCTTCTTCCTG CTCAGCGCCAGCATCATCCCCAATGGCTTCACCGGCCTGTCCTCCGTGTTCCTGATAGCG ACCCCGGAGCACCGCTGCCGGGTGCCGGACGCCGCGAACCTGAGCAGCGCCTGGCGCAAC CACACTGTCCCACTGCGGCTGCGGGACGGCCGCGAGGTGCCCCACAGCTGCCGCCGCTAC CGGCTCGCCACCATCGCCAACTTCTCGGCGCTCGGGCTGGAGCCGGGGCGCGACGTGGAC CTGGGGCAGCTGGAGCAGGAGAGCTGTCTGGATGGCTGGGAGTTCAGTCAGGACGTCTAC CTGTCCACCATTGTGACCGAGTGGAACCTGGTGTGTGAGGACGACTGGAAGGCCCCACTC ACAATCTCCTTGTTCTTCGTGGGTGTGCTGTTGGGCTCCTTCATTTCAGGGCAGCTGTCA GACAGGTTTGGCCGGAAGAATGTGCTGTTCGTGACCATGGGCATGCAGACAGGCTTCAGC TTCCTGCAGATCTTCTCGAAGATTTTGAGATGTNTGTCGTGCTGTTTGTCCTTGTANGCA TGGGCCAGATCTCAACTATGTGGCAGCATTTGTCCTGGGGACAGAAATTCTTGGNCAGTC AGTTCGTATATATTCTCTACGTTAGAGTGTG >OriGene 3' read for NM_003060 unedited
TACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTTGATATTTAAAA AATCATTTTACTTATTAAAACTTTCTCATTTCCCAAGGCACTTCAGTAGCTTTCACAAAA ACATGTTTGTTCTTTTTTAACCAGGTGAGGCATATGCTTTAGGAGTACCATGGTAACATA ATCAGCAAAGAGAAGACAATTACACTGAACACAAAATATCACCCAATAAAGTTACAGGAC TAAAGTGAGCTACTCTGAAAGACTATGAACACAATTTAAATTTCTTTTTTGTAATATCCT CCCATGACTAAGTATCAAGAAAGGAACACACACAATGACACTGTTTTTGGCACTTAAAGA AGTGCTAGAGGCTAGGGCTGGTAAGGCCTTGCACCAGTGGCAGCTGCAGACAATTGCCAG AGTGATTCTGTGTTTAAAAAAAAAAAAAAAAGACCCAAACCACGAGGCTAAGGAACCAGC CTTTCCCAAGTGCTTTCTGAAGGGCAAATAACAAGGAGAAAAGGATACACCCCCAAACAA ATTAACCGTATAACAAAACCCACATTACAGCTTTGAGAGAAAAGACATCGTTGCTCATTT CTTTCACCTGAAAATGTACCTTTAAACCATACATTAAAACGCTTATATGTGCCAGGAGGC GTCCCCCCGGCCTGTGAAACCGACACCTGAACACACGATGGAAACATTAATTCTGAACCC TTGGACCACCCACTCGCCTTTCTCTCAATGAAGACCACCTCTGTCTCATATAAGTTGCTG TATGGTAGCGAGCAACTACGCCCCTCGTCCACGCCCGTGACCGAAGTACGTCCTTNCTAT ATCCATTCGTATAGCATAGAGAGAGTACCGGTACTCAATACNCACACGCCGCGAATGATC ACATCTCAACAACACTAACCATTATCGCACGACACCGCACATGCCATCAAATGTATGAAT CCACCTACACATAATACACAG |
Restriction Sites | NotI-NotI |
ACCN | NM_003060 |
Insert Size | 3370 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_003060.2, NP_003051.1 |
RefSeq Size | 3252 bp |
RefSeq ORF | 1674 bp |
Locus ID | 6584 |
UniProt ID | O76082 |
Domains | sugar_tr |
Protein Families | Transmembrane |
Gene Summary | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204177 | SLC22A5 (Myc-DDK-tagged)-Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5) |
CNY 4,152.00 |
|
RC204177L1 | Lenti ORF clone of Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5), Myc-DDK-tagged |
CNY 6,552.00 |
|
RC204177L2 | Lenti ORF clone of Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5), mGFP tagged |
CNY 5,890.00 |
|
RC204177L3 | Lenti ORF clone of Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204177L4 | Lenti ORF clone of Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5), mGFP tagged |
CNY 5,890.00 |
|
RG204177 | SLC22A5 (tGFP-tagged) - Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5) |
CNY 5,752.00 |
|
SC324472 | SLC22A5 (untagged)-Human solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5) |
CNY 4,152.00 |
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