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UBE2L3 (NM_003347) Human Untagged Clone
CAT＃: SC118049
UBE2L3 (untagged)-Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1
CNY 1,200.00
CNY 3,990.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | E2-F1; L-UBC; UBCH7; UbcM4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_003347 edited
ATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAA AACTTCCGTAACATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTT CCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAG TACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGAC GAAAAGGGGCAGGTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAA ACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAATGACCCCCAGCCTGAGCACCCG CTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCT GAAGAGTTTACAAAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTG GTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCATTCAGACACCCCGCAAAGCAGGA CTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTC TACAGTTTTCTTAATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAA GATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACTGCTTCAATCTACTTCAAAAGAA TGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAG GTTTAAAAAAAAAAAAAAAAAACTCGA >OriGene 5' read for NM_003347 unedited
TTTTCACCATTTTGTCATACGATTTACTATAGGCGGCCGCGAAATTCGCACGAGGCCAAG ATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAACCGCAAAGTGGGATGAAAAA CTTCCGTAACATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTTCC TGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGTA CCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGA AAAGGGGCAGGTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAAC CGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAATGACCCCCAGCCTGAGCACCCGCT TCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGA AGAGTTTACAAAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGT TCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCATTCAGACACCCCGCANAGCATGACT CTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTTGTGGCAGTTACTAACTTTCT ACAGTTTTCTTAATCAAAAGTGGTCTATGTAACCTGTAAAGAAAGGATTAAAAATTAAAG ATGTTCTAGTTTCTGCTCTCTTTGTTTTAAAATCACTGCTCCAATCTACTTCAAAAGATG GTGTTTCTTTTTTTTGTCCAATTTATCCAAAATCTTTAAGTTACATTTTAACCCATAAAG GTTTAAAAAAATAAAAAAAAAAACTCGCACTTTTAAATTGCGGCCCGGGGTCATATACTG GTTTCCTTGAAAGAATCTCCGGTGGTCTATTTCTGNGAACCCCTTCCCCG >OriGene 3' read for NM_003347 unedited
CCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTAAACCTTATGGGTTAAATGTAACT TGAAGATTTTGGATAAAATTGGACAAGAAAAGAAACACCATTCTTTTGAAGTAGATTGAA GCAGTGATTTTTAAAACAAAGAGAGCAGAACTAGAACATCTTAAATTTTTAATCCTTTCT TTACAGGTTACCTAGACCACTTTTGATTAAGAAAACTGTAGAAAGTTAGTAACTGCCACA AGCGAACGCCAGGCGGTGGCACGTGTCAATTTCCACAGAGTCCTGCTTTGCGGGGTGTCT GAATGCACTGCACGGGGTCTCTGCTCACACTTGCTGGAACCAATCGTGGCAGATTTTAGT CCACAGGTCGCTTTTCCCCATATTTCTTTGTAAACTCTTCAGCATTCTTACAGAATTTTT TACGGTCCTTAGAGTATTCTTCAGCTAGGTCAGCCCGAAGCGGGTGCTCAGGCTGGGGGT CATTCACCAGTGCTATGAGGGACTGGATTACTTGGTCGGTTTTGGTTGCTGGCTTCCAGT TTTCGGCACTAATTACTGGCAGACAGACCTGCCCCTTTTCGTCGATGTTTGAGTGATAGA TCTTTGTTCTAATGTGATCTTCGGAGGTTTGAATGGGTACTCTGCTGAAAAGTGATTTCG ATTCTGAAGGCTCCCTTANATATGGAGGCNTGCAGGAACAATAGCCCCTGCCAGTCATAA ATTAGCTCATCAACCTGGAGTTACGGAAGTTTTTATCCACATTTGCGGATTTTTAAGCTC CTTATAGCCTCCTGTGCCCGCTCTGGGCTTTGCCGATTCGCGGCGGCTTTGGAGGCGATT ACAAATCTGAGGTTACTAACCAGCTTGCTTTTTGGACTCCACCGACCGCCTAACGGCATT GGTAACGGGGCGGGGATTACAATTTTGGAAGCCGCGTGTTTGGGCCAACAAATCCTTGCG G |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003347 |
| Insert Size | 820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003347.2, NP_003338.1 |
| RefSeq Size | 2907 bp |
| RefSeq ORF | 465 bp |
| Locus ID | 7332 |
| UniProt ID | P68036 |
| Protein Pathways | Parkinson's disease, Ubiquitin mediated proteolysis |
| Gene Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) uses an alternate 5' splice site and downstream translational start site, compared to variant 4. It encodes a shorter and distinct N-terminus in isoform 1, compared to isoform 4. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1
,Liu, H;Qiu, H;Song, Y;Liu, Y;Wang, H;Lu, M;Deng, M;Gu, Y;Yin, J;Luo, K;Zhang, Z;Jia, X;Zheng, G;He, Z;,
Oncogene
,PubMed ID 27694903
[UBE2L3]
|
|
UBE2L3 Polymorphism Amplifies NF-?B Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
,Lewis, MJ;Vyse, S;Shields, AM;Boeltz, S;Gordon, PA;Spector, TD;Lehner, PJ;Walczak, H;Vyse, TJ;,
Am. J. Hum. Genet.
,PubMed ID 25640675
[UBE2L3]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208780 | UBE2L3 (Myc-DDK-tagged)-Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1 |
CNY 1,200.00 |
|
| RC208780L1 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC208780L2 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC208780L3 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC208780L4 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1, mGFP tagged |
CNY 3,600.00 |
|
| RG208780 | UBE2L3 (tGFP-tagged) - Human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1 |
CNY 2,800.00 |
