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Ezrin (EZR) (NM_003379) Human Untagged Clone
CAT＃: SC117991
EZR (untagged)-Human ezrin (EZR), transcript variant 1
CNY 6,552.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CVIL; CVL; HEL-S-105; VIL2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_003379 edited
ATGCCGAAACCAATCAATGTCCGAGTTACCACCATGGATGCAGAGCTGGAGTTTGCAATC CAGCCAAATACAACTGGAAAACAGCTTTTTGATCAGGTGGTAAAGACTATCGGCCTCCGG GAAGTGTGGTACTTTGGCCTCCACTATGTGGATAATAAAGGATTTCCTACCTGGCTGAAG CTGGATAAGAAGGTGTCTGCCCAGGAGGTCAGGAAGGAGAATCCCCTCCAGTTCAAGTTC CGGGCCAAGTTCTACCCTGAAGATGTGGCTGAGGAGCTCATCCAGGACATCACCCAGAAA CTTTTCTTCCTCCAAGTGAAGGAAGGAATCCTTAGCGATGAGATCTACTGCCCCCCTGAG ACTGCCGTGCTCTTGGGGTCCTACGCTGTGCAGGCCAAGTTTGGGGACTACAACAAAGAA GTGCACAAGTCTGGGTACCTCAGCTCTGAGCGGCTGATCCCTCAAAGAGTGATGGACCAG CACAAACTTACCAGGGACCAGTGGGAGGACCGGATCCAGGTGTGGCATGCGGAACACCGT GGGATGCTCAAAGATAATGCTATGTTGGAATACCTGAAGATTGCTCAGGACCTGGAAATG TATGGAATCAACTATTTCGAGATAAAAAACAAGAAAGGAACAGACCTTTGGCTTGGAGTT GATGCCCTTGGACTGAATATTTATGAGAAAGATGATAAGTTAACCCCAAAGATTGGCTTT CCTTGGAGTGAAATCAGGAACATCTCTTTCAATGACAAAAAGTTTGTCATTAAACCCATC GACAAGAAGGCACCTGACTTTGTGTTTTATGCCCCACGTCTGAGAATCAACAAGCGGATC CTGCAGCTCTGCATGGGCAACCATGAGTTGTATATGCGCCGCAGGAAGCCTGACACCATC GAGGTGCAGCAGATGAAGGCCCAGGCCCGGGAGGAGAAGCATCAGAAGCAGCTGGAGCGG CAACAGCTGGAAACAGAGAAGAAAAGGAGAGAAACCGTGGAGAGAGAGAAAGAGCAGATG ATGCGCGAGAAGGAGGAGTTGATGCTGCGGCTGCAGGACTATGAGGAGAAGACAAAGAAG GCAGAGAGAGAGCTCTCGGAGCAGATTCAGAGGGCCCTGCAGCTGGAGGAGGAGAGGAAG CGGGCACAGGAGGAGGCCGAGCGCCTAGAGGCTGACCGTATGGCTGCACTGCGGGCTAAG GAGGAGCTGGAGAGACAGGCGGTGGATCAGATAAAGAGCCAGGAGCAGCTGGCTGCGGAG CTTGCAGAATACACTGCCAAGATTGCCCTCCTGGAAGAGGCGCGGAGGCGCAAGGAGGAT GAAGTTGAAGAGTGGCAGCACAGGGCCAAAGAAGCCCAGGATGACCTGGTGAAGACCAAG GAGGAGCTGCACCTGGTGATGACAGCACCCCCGCCCCCACCACCCCCCGTGTACGAGCCG GTGAGCTACCATGTCCAGGAGAGCTTGCAGGATGAGGGCGCAGAGCCCACGGGCTACAGC GCGGAGCTGTCTAGTGAGGGCATCCGGGATGACCGCAATGAGGAGAAGCGCATCACTGAG GCAGAGAAGAACGAGCGTGTGCAGCGGCAGCTGCTGACGCTGAGCAGCGAGCTGTCCCAG GCCCGAGATGAGAATAAGAGGACCCACAATGACATCATCCACAACGAGAACATGAGGCAA GGCCGGGACAAGTACAAGACGCTGCGGCAGATCCGGCAGGGCAACACCAAGCAGCGCATC GACGAGTTCGAGGCCCTGTAA >OriGene 5' read for NM_003379 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTCTGACTCCAGGTT GGGACAGCGTCTTCGCTGCTGCTGGATAGTCGTGTTTTCGGGGATCGAGGATACTCACCA GAAACCGAAAATGCCGAAACCAATCAATGTCCGAGTTACCACCATGGATGCAGAGCTGGA GTTTGCAATCCAGCCAAATACAACTGGAAAACAGCTTTTTGATCAGGTGGTAAAGACTAT CGGCCTCCGGGAAGTGTGGTACTTTGGCCTCCACTATGTGGATAATAAAGGATTTCCTAC CTGGCTGAAGCTGGATAAGAAGGTGTCTGCCCAGGAGGTCAGGAAGGAGAATCCCCTCCA GTTCAAGTTCCGGGCCAAGTTCTACCCTGAAGATGTGGCTGAGGAGCTCATCCAGGACAT CACCCAGAAACTTTTCTTCCTCCAAGTGAAGGAAGGAATCCTTAGCGATGAGATCTACTG CCCCCCTGAGACTGCCGTGCTCTTGGGGTCCTACGCTGTGCAGGCCAAGTTTGGGGACTA CAACAAAGAAGTGCACAAGTCTGGGTACCTCAGCTCTGAGCGGCTGATCCCTCAAAGAGT GATGGACCAGCACAAACTTACCAGGGACCAGTGGGAGGACCGGATCCAGGTGTGGCATGC GGAACACCGTGGGATGCTCAAAGATAATGCTATGTTGGAATACCTGAAGATTGCTCANGA CCTGNAAATGTATGGAATCAACTATTTCGAGATAAAAAACAAGAAGGAACAGACCTTTGG CTTGGNAGTNGATGCCCTTGGACTGAATATTTATGAGAAAGATGATAAGNTAACCCNCAA GATTGGCTTTCCTTGGNAGTGAATCANGAACATCTCTTTCAATGACAAAAN >OriGene 3' read for NM_003379 unedited
GCACGCAATCTAGAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATAGGAAA TTCTTTTATTCTGTAAAAGGTAACAAATTATACAGAACAAAACTTTCCCTTTTTAAAACT AATGTTACAAATCTGTATTATCACTTGTATATAAATAGTATATAGCTGATCATTAATAAG GGGTATAAGTACAATGTATTCTAAAACTGTTAAGCCAAAAAAAAAAAACTAAAAAAATAT CCAAGGGTCCTCCTCCACCACTCACGCTGGGGATCACTGGGCTCTCTGCCACCTGCGTGG ATTGACGGGAGGAGGGAATCACTGTGTGTGCAAAAGTGCTTCAAACTCAATTTCCAAAAT AATTTTCACCCCTCTAAGCATGTAAATATACAAAGATGGATCCTTCATAAAAATTAAAAA ATCAATTGGAGCTCATTTCAAATACAAAACAAGTATGGCACAAATGGAAGTCCTGCCACG TTTCCTTTAATGATGCTGACTCTTGTATCACACAGGCCAGCATGAAGTTTCTTACTCAAA CTTTACAGGCATTTTCCGTAATTCAATCAGTCCTGCTCCCAGCACAACACAGGAGGTGAT TCGAGAATAATCGCGAGATTCAGGCCTGCTTGGCACTATTACAACTGGGGAAAACAAACC AGGGCGCCTCCCTGGTTCCCAGCCCAAAATGTTTCTGTTGGGTAACTGCTTTCTAAAGGA ACTGGGATCTGAGGGAGTTCCTATACTTGGAGCACTAAAGACAAGCGTGGGCGGGCCTGC ATCCGCCCGCTATGACCACCCCTCTGCCCTTGGTCCTGCCCTGGCTGTTACAGGGCCTTA ATCTCTCAATGCCCTGTTGGTNGTGCCCTGCCAGATCTTGCGCAAGGTTTGTACTTGTCC AGGCCTGCCTATGTTCCGTTGGGATGAGCATGGGGGCCTCTTTTCTTATTGGCCTGGACA TCTCGTGTCAAGTAANATTGCCGTGACACCTGTCTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003379 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003379.3, NP_003370.2 |
| RefSeq Size | 3166 bp |
| RefSeq ORF | 1761 bp |
| Locus ID | 7430 |
| UniProt ID | P15311 |
| Domains | B41, ERM |
| Protein Families | Druggable Genome |
| Protein Pathways | Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton |
| Gene Summary | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200404 | EZR (Myc-DDK-tagged)-Human ezrin (EZR), transcript variant 1 |
CNY 6,544.00 |
|
| RC200404L1 | Lenti ORF clone of Human ezrin (EZR), transcript variant 1, Myc-DDK-tagged |
CNY 8,944.00 |
|
| RC200404L2 | Lenti ORF clone of Human ezrin (EZR), transcript variant 1, mGFP tagged |
CNY 8,944.00 |
|
| RC200404L3 | Lenti ORF clone of Human ezrin (EZR), transcript variant 1, Myc-DDK-tagged |
CNY 8,944.00 |
|
| RC200404L4 | Lenti ORF clone of Human ezrin (EZR), transcript variant 1, mGFP tagged |
CNY 8,944.00 |
|
| RG200404 | EZR (tGFP-tagged) - Human ezrin (EZR), transcript variant 1 |
CNY 8,144.00 |
|
| SC320852 | EZR (untagged)-Human ezrin (EZR), transcript variant 1 |
CNY 6,552.00 |
