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MAD1 (MAD1L1) (NM_003550) Human Untagged Clone
CAT＃: SC117934
MAD1L1 (untagged)-Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1
CNY 5,264.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MAD1; PIG9; TP53I9; TXBP181 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117934 sequence for NM_003550 edited (data generated by NextGen Sequencing)
ATGGAAGACCTGGGGGAAAACACCATGGTTTTATCCACCCTGAGATCTTTGAACAACTTC ATCTCTCAGCGTGTGGAGGGAGGCTCTGGACTGGATATTTCTACCTCGGCCCCAGGTTCT CTGCAGATGCAGTACCAGCAGAGCATGCAGCTGGAGGAAAGAGCAGAGCAGATCCGTTCG AAGTCCCACCTCATCCAGGTGGAGCGGGAGAAAATGCAGATGGAGCTGAGTCACAAGAGG GCTCGAGTGGAGCTGGAGAGAGCAGCCAGCACCAGTGCCAGGAACTACGAGCGTGAGGTC GACCGCAACCAGGAGCTCCTGACGCGCATCCGGCAGCTTCAGGAGCGGGAGGCCGGGGCG GAGGAGAAGATGCAGGAGCAGCTGGAGCGCAACAGGCAGTGTCAGCAGAACTTGGATGCT GCCAGCAAGAGGCTGCGTGAGAAAGAGGACAGTCTGGCCCAGGCTGGCGAGACCATCAAC GCACTGAAGGGGAGGATCTCGGAACTGCAGTGGAGCGTGATGGACCAGGAGATGCGGGTG AAGCGCCTGGAGTCGGAGAAGCAGGAGCTGCAGGAGCAGCTGGACCTGCAACACAAAAAA TGCCAGGAAGCCAATCAGAAAATCCAGGAACTCCAGGCCAGCCAAGAAGCAAGAGCAGAC CATGAGCAGCAGATTAAGGATCTGGAGCAGAAGCTGTCCCTGCAAGAGCAGGATGCAGCG ATTGTGAAGAACATGAAGTCTGAGCTGGTACGGCTCCCTAGGCTGGAACGGGAGCTGAAG CAGCTGCGGGAGGAGAGCGCGCACCTGCGGGAGATGAGAGAGACCAACGGGCTGCTCCAG GAAGAGCTGGAAGGGCTGCAGAGGAAGCTGGGGCGCCAGGAGAAGATGCAGGAGACGCTG GTTGGCTTGGAGCTGGAGAACGAGAGGCTGCTGGCCAAGCTGCAAAGCTGGGAGAGACTG GACCAGACCATGGGCCTGAGCATCAGGACTCCAGAAGACCTTTCCAGATTCGTGGTTGAG CTGCAGCAGAGGGAGCTTGCCTTGAAGGACAAGAACAGCGCCGTCACCAGCAGCGCCCGG GGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTG TTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGG GTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGC GAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGAT ATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTG GAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTG AAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACG CTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGG ATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACC AAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCACGAGGAC CACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGA GGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAG GTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAG ATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGC GACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATC CCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAG Clone variation with respect to NM_003550.2 663 c=>t;1673 g=>a >OriGene 5' read for NM_003550 unedited
GTGTTAGAATTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGCGGCGGCA AGCTGGCTGCGAGCGGCTGAGCAGCACTCCAAGCTCGCCGGCCTTTGGTCTCCAGGACTT GTCCCAGCAGCCCCTCGAACTGAGAATTACACCATCGGACCCCTGGCTCTGAGGCCTTCA GACTTGGACTGTGTCACACTGCCAGGCTTCCAGGGCTCCAACTTGCAGACGGCCTGTTGT GGGACAGTCTCTGTAATCGCGAAAGCAACCATGGAAGACCTGGGGGAAAACACCATGGTT TTATCCACCCTGAGATCTTTGAACAACTTCATCTCTCAGCGTGTGGAGGGAGGCTCTGGA CTGGATATTTCTACCTCGGCCCCAGGTTCTCTGCAGATGCAGTACCAGCAGAGCATGCAG CTGGAGGAAAGAGCAGAGCAGATCCGTTCGAAGTCCCACCTCATCCAGGTGGAGCGGGAG AAAATGCAGATGGAGCTGAGTCACAAGAGGGCTCGAGTGGAGCTGGAGAGAGCAGCCAGC ACCAGTGCCAGGAACTACGAGCGTGAGGTCGACCGCAACCAGGAGCTCCTGACGCGCATC CGGCAGCTTCAGGAGCGGGAGGCCGGGGCGGAGGAGAAGATGCAGGAGCAGCTGGAGCGC AACAGGCCGTGTCAGCAGAACTTGGATGCTGCCAGCAAGAGGCTGCGTGAGACAGAAGAC AGTCTGGCCCAGGCTGTCGAGACCATCAACGCACTGAANGGNAGGATCTCGGAACTGCAG TGCAACGTGATGGACCACGAGATGCGGGTGAAACGCCTGAAGTCGGAGAAGCAGAGCTGC AAGAGCANCTGAACCTGCAACACAAAAAAGCCAGGAACCCATTCAGAAATCCAGNACCTC CG >OriGene 3' read for NM_003550 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTCTAGGGGAGAAGATTTTATT TCACAAGGTGAGGAACCCAGGCTGGTGGCCGACGCCCACACACCAGGCTCCGGGACGCAT GGGGTCTGCACGTGGAGAGGGTGCTGGCCGCCCCAGCAGGAAGCCCGACGTAGGTCCCAG CGTGTCTGTCAGTCATGCTGCTGCCCTGTGGGGCTGGAGAGGCAGGACGTGCACCCAGCC TGTGGCTGGCGGGGCAGGGGACCTGCAGGTCAGGCCAAGCAGAGTGGCTCCGGCTATGCC CCCGAGCCTGCAGGCTACGCCACGGTCTGGCGGCTGAAGAGCTCGAGGGTGAGCGAGCTG AGGAAGGCAGGGATGCTGTCCTGGCGCCGCAGGTGCACCTCGATGAGCTCGCCCACGGTG TGTGAGAACTCTGTCTCCAGTAGCTGCATCTTGGAACCCGAGGGGCTGGTGGCCTTGAAG ATGAGGCAGTCGCCTGGGTGCTCGGCGTACAGCGAGGTCAGCCGGTACTGGTTCTCCGTG GTGATGTCGATCTGGTAGCCCGTGAGCGTGTAGCAGGCCTTGCCGAACTNCTGGATCTTG GTCTGGNAAACCTCCCTGAGCCGCTGTTNTTCAGCTCGGCACTCTTCACCTGCTTNTTCA GCTCTGCCACCTCCCGGNACGATGGCAGACTCGCGCCGGCAGCCTCAGGTCNGCTGGGAC GGTGCCTCCCTCTTCATGGCGCGCAGGACCCGCGCAGTCGCTCGCACTCCGCCTGAACTG CCTGTGGCCTCGTGCAGCCCCTGCTGGCACCCTGGTGGGGTTCAAGCTCATGGGCCCCAC TTTTGGCCCTGCCTGGGCATAGCAACCCTGCAGAGCTTGCGTTCACCTGTGCCTTCAGAT CTTTTTTCTTCTCCAGCGATCCGGTGGCTTCAAGTTCTGACTTAACTGAGGGGGCCGCTC TCCTGAAAACNGAACTTGTTCGGCAACTGGCTGAACTAAAACTTACCCCATCTCAAAGCT GGTCTTGTTCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003550 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003550.2, NP_003541.2 |
| RefSeq Size | 2754 bp |
| RefSeq ORF | 2157 bp |
| Locus ID | 8379 |
| UniProt ID | Q9Y6D9 |
| Protein Families | Druggable Genome |
| Protein Pathways | Cell cycle |
| Gene Summary | MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1-4 encode the same isoform. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eµ-miR-155 transgenic mouse model
,Sukhinder K. Sandhu, Stefano Volinia, Stefan Costinean, Marco Galasso, Reid Neinast, Ramasamy Santhanam, Mark R. Parthun, Danilo Perrotti, Guido Marcucci, Ramiro Garzon, and Carlo M. Croce,
PNAS, Dec 2012; 109: 20047 - 20052.
[MAD1L1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203471 | MAD1L1 (Myc-DDK-tagged)-Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1 |
CNY 5,256.00 |
|
| RC203471L1 | Lenti ORF clone of Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203471L2 | Lenti ORF clone of Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203471L3 | Lenti ORF clone of Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203471L4 | Lenti ORF clone of Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG203471 | MAD1L1 (tGFP-tagged) - Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1 |
CNY 6,856.00 |
