S1P (MBTPS1) (NM_003791) Human Untagged Clone

CAT#: SC117763

MBTPS1 (untagged)-Human membrane-bound transcription factor peptidase, site 1 (MBTPS1)



  "NM_003791" in other vectors (6)

CNY 7,336.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit polyclonal anti-MBTPS1 antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms PCSK8; S1P; SEDKF; SKI-1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_003791, the custom clone sequence may differ by one or more nucleotides


ATGAAGCTTGTCAACATCTGGCTGCTTCTGCTCGTGGTTTTGCTCTGTGGGAAGAAACATCTGGGCGACA
GACTGGAAAAGAAATCTTTTGAAAAGGCCCCATGCCCTGGCTGTTCCCACCTGACTTTGAAGGTGGAATT
CTCATCAACAGTTGTGGAATATGAATATATTGTGGCTTTCAATGGATACTTTACAGCCAAAGCTAGAAAT
TCATTTATTTCAAGTGCCCTGAAGAGCAGTGAAGTAGACAATTGGAGAATTATACCTCGAAACAATCCAT
CCAGTGACTACCCTAGTGATTTTGAGGTGATTCAGATAAAAGAAAAACAGAAAGCGGGGCTGCTAACACT
TGAAGATCATCCAAACATCAAACGGGTCACGCCCCAACGAAAAGTCTTTCGTTCCCTCAAGTATGCTGAA
TCTGACCCCACAGTACCCTGCAATGAAACCCGGTGGAGCCAGAAGTGGCAATCATCACGTCCCCTGCGAA
GAGCCAGCCTCTCCCTGGGCTCTGGCTTCTGGCATGCTACGGGAAGGCATTCGAGCAGACGGCTGCTGAG
AGCCATCCCGCGCCAGGTTGCCCAGACACTGCAGGCAGATGTGCTCTGGCAGATGGGATATACAGGTGCT
AATGTAAGAGTTGCTGTTTTTGACACTGGGCTGAGCGAGAAGCATCCCCACTTCAAAAATGTGAAGGAGA
GAACCAACTGGACCAACGAGCGAACGCTGGACGATGGGTTGGGCCATGGCACATTCGTGGCAGGTGTGAT
AGCCAGCATGAGGGAGTGCCAAGGATTTGCTCCAGATGCAGAACTTCACATTTTCAGGGTCTTTACCAAT
AATCAGGTATCTTACACATCTTGGTTTTTGGACGCCTTCAACTATGCCATTTTAAAGAAGATCGACGTGT
TAAACCTCAGCATCGGCGGCCCGGACTTCATGGATCATCCGTTTGTTGACAAGGTGTGGGAATTAACAGC
TAACAATGTAATCATGGTTTCTGCTATTGGCAATGACGGACCTCTTTATGGCACTCTGAATAACCCTGCT
GATCAAATGGATGTGATTGGAGTAGGCGGCATTGACTTTGAAGATAACATCGCCCGCTTTTCTTCAAGGG
GAATGACTACCTGGGAGCTACCAGGAGGCTACGGTCGCATGAAACCTGACATTGTCACCTATGGTGCTGG
CGTGCGGGGTTCTGGCGTGAAAGGGGGGTGCCGGGCCCTCTCAGGGACCAGTGTTGCTTCTCCAGTGGTT
GCAGGTGCTGTCACCTTGTTAGTGAGCACAGTCCAGAAGCGTGAGCTGGTGAATCCCGCCAGTATGAAGC
AGGCCCTGATCGCGTCAGCCCGGAGGCTCCCCGGGGTCAACATGTTTGAGCAAGGCCACGGCAAGCTCGA
TCTGCTCAGAGCCTATCAGATCCTCAACAGCTACAAGCCACAGGCAAGTTTGAGCCCCAGCTACATAGAT
CTGACTGAGTGTCCCTACATGTGGCCCTACTGCTCCCAGCCCATCTACTATGGAGGAATGCCGACAGTTG
TTAATGTCACCATCCTCAACGGCATGGGAGTCACAGGAAGAATTGTAGATAAGCCTGACTGGCAGCCCTA
TTTGCCACAGAACGGAGACAACATTGAAGTTGCCTTCTCCTACTCCTCGGTCTTATGGCCTTGGTCGGGC
TACCTGGCCATCTCCATTTCTGTGACCAAGAAAGCGGCTTCCTGGGAAGGCATTGCTCAGGGCCATGTCA
TGATCACTGTGGCTTCCCCAGCAGAGACAGAGTCAAAAAATGGTGCAGAACAGACTTCAACAGTAAAGCT
CCCCATTAAGGTGAAGATAATTCCTACTCCCCCGCGAAGCAAGAGAGTTCTCTGGGATCAGTACCACAAC
CTCCGCTATCCACCTGGCTATTTCCCCAGGGATAATTTAAGGATGAAGAATGACCCTTTAGACTGGAATG
GTGATCACATCCACACCAATTTCAGGGATATGTACCAGCATCTGAGAAGCATGGGCTACTTTGTAGAGGT
CCTCGGGGCCCCCTTCACGTGTTTTGATGCCAGTCAGTATGGCACTTTGCTGATGGTGGACAGTGAGGAG
GAGTACTTCCCTGAAGAGATCGCCAAGCTCCGGAGGGACGTGGACAACGGCCTCTCGCTCGTCATCTTCA
GTGACTGGTACAACACTTCTGTTATGAGAAAAGTGAAGTTTTATGATGAAAACACAAGGCAGTGGTGGAT
GCCGGATACCGGAGGAGCTAACATCCCAGCTCTGAATGAGCTGCTGTCTGTGTGGAACATGGGGTTCAGC
GATGGCCTGTATGAAGGGGAGTTCACCCTGGCCAACCATGACATGTATTATGCGTCAGGGTGCAGCATCG
CGAAGTTTCCAGAAGATGGCGTCGTGATAACACAGACTTTCAAGGACCAAGGATTGGAGGTTTTAAAGCA
GGAAACAGCAGTTGTTGAAAACGTCCCCATTTTGGGACTTTATCAGATTCCAGCTGAGGGTGGAGGCCGG
ATTGTACTGTATGGGGACTCCAATTGCTTGGATGACAGTCACCGACAGAAGGACTGCTTTTGGCTTCTGG
ATGCCCTCCTCCAGTACACATCGTATGGGGTGACACCGCCTAGCCTCAGTCACTCTGGGAACCGCCAGCG
CCCTCCCAGTGGAGCAGGCTCAGTCACTCCAGAGAGGATGGAAGGAAACCATCTTCATCGGTACTCCAAG
GTTCTGGAGGCCCATTTGGGAGACCCAAAACCTCGGCCTCTACCAGCCTGTCCACGCTTGTCTTGGGCCA
AGCCACAGCCTTTAAACGAGACGGCGCCCAGTAACCTTTGGAAACATCAGAAGCTACTCTCCATTGACCT
GGACAAGGTGGTGTTACCCAACTTTCGATCGAATCGCCCTCAAGTGAGGCCCTTGTCCCCTGGAGAGAGC
GGCGCCTGGGACATTCCTGGAGGGATCATGCCTGGCCGCTACAACCAGGAGGTGGGCCAGACCATTCCTG
TCTTTGCCTTCCTGGGAGCCATGGTGGTCCTGGCCTTCTTTGTGGTACAAATCAACAAGGCCAAGAGCAG
GCCGAAGCGGAGGAAGCCCAGGGTGAAGCGCCCGCAGCTCATGCAGCAGGTTCACCCGCCAAAGACCCCT
TCGGTGTGA


>OriGene 5' read for NM_003791 unedited
GGGCACATTTGTATACGACTCCTATAGGCGGCNCGCGATTCGGCACGAGGCGGCGGAGCT
GAGGCTCCCAGCTGTGGGCCTCGCTGGCCCGGTCGCCCAGTCTCGCGAGAGTTGGGAGTA
AACAGCCCCGAATGGAGTGCCCAGGCGTGTTCGCCGCGGAGGCGCCGTTATCCCGGGCCC
GCCGGCCCTGAGCTCCCGGCGGCGCAGATTGGCTCACAGTGGTTGATTGATCAACCCCAT
TGGACGTTGGTTCTGTGGTACAAATGGAGTACAGGACTCAGTCGTCACGGCCTGAGTGAG
AGAAGCCTTATTTCCAAGATGGAGAAGAAGCGGAGAAAGAAATGAAAGCCTCTCTTCAGG
CTGAACCACAAAAGGCCATGGGATTTAACTTTTATTTATGTTGGGCAAGACTGTAAGATG
GCTGATTAGTAATGTTGCAGCTTTTAGCTGAAACAAAAATTCACTTTTAATCAAGAAGAA
AAAAGTGTGATTTGAATATATGCAATTTTATGATCATATTCGCTTGTGACCATGAAGCTT
GTCAACATCTGGCTGCTTCTGCTCGTGGTTTTGCTCTGTGGGAAGAAACATCTGGGCGAC
AGACTGGAAAAGAAATCTTTTGAAAAGGCCCCATGCCCTGNCTGTTCCCACCTGACTNTG
AAGGTGGAATTCTCATCAACAGTTGTGGAATATGAATATATTGTGGCTTTCAATGGATAC
TNTACAGCCAAAGCTAGAAATTCATTTATTTCAAGTGCCCCTGAGAGCAGTGAAGTAGAC
AATTGGAGAAATATACCTCGAANCAATNCATCCAGTGACTACCCTAGTGATTTTGAGGGT
GATCAGATAAAGAAAAACAGAAAGCGGGCTGCTAACACTTGAAGACATNCAANCATCAAC
CGGTCACGCCCC
>OriGene 3' read for NM_003791 unedited
TGCACCGCGGCACGCAATCTAGCATCGAGTTTTTTTTTTTTTTTTTTAAGCTTCAAACGG
GTAATACATATTTATTGAAAATTTTCTTCACCGACAATGGTGAAATCAAGACCTCAAATT
ACAAAACATGGCGGCAGGTGATACTTACAAAAATAAAGCGAAGGTCTATGTTTTACAGAT
TAGTGCATGTTACCTTTAAATCTCAGCCTGTCCTGCCATTAAAAAGCATCATGGTATCTA
TGTTGTCTCTTATGATGGATTACCCAAAAAACTGCATTTCACTGACAAAAAAAATATCTT
TGCTTGTAAATAGCACAATTTTTTAAAGCGACTTTTTTCATCAATAAATATAGAAAATAT
CCTTCACCACTCGCCCTTAACCTTGCTCACGTTTGTCTTATTTGTCCGCAAAGCCATCCC
TTTCCCTGTTGTATCACACTGCTCACACTCTCTTTTCTACTTCCACCTATTCTTTGGTGT
CATCACTCTTTCGACCGACAATTCTTACCGGTGGCTCAATCACTAAATTCCTTCTGTCGG
TATCTTTAAGATTCACTCCTCATGTTCATCTACCCCTCTGTACTTTAAAGATGCTCCTTC
CTGCTTAATATATCTTATCTATTTTTATCACATAAACTGTTTTATTTTAATACTTTCTAT
AACCACGCTCCGTTACACCATTTTTTGTTCCTATCTTATATGCCACATCTTTGGTTCCTC
CCCGCCCACTCCTTCTTCCCTTTTTATCTCTCTAGGGTATTATTTTCAGTCGTACCTCAT
TCATTTGCACCCTCCCCTCCTCCTCCCATTGATTTTCCTCTCTTATCCCCTTCCCCCGAC
TTCTCAATATTTTTATTCCCGCATTAGCCCTTATTTCTTTCGTTTTTTCTTCACTCTCTC
ACCGTATATAATCGACTTCCCTTCTCTTTTTTTATTTATTCTCAACTCCCCACACGTGAA
TACCCTGTCCCTACCACTGGTCATAGTTTATTCCCTTGTTTATTATCTTTCTCTCCCCAA
TTCACATATTCATTCTACTT
Restriction Sites NotI-NotI     
ACCN NM_003791
Insert Size 4650 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003791.2, NP_003782.1
RefSeq Size 4354 bp
RefSeq ORF 3159 bp
Locus ID 8720
UniProt ID Q14703
Domains Peptidase_S8
Protein Families Druggable Genome, Protease, Transcription Factors, Transmembrane
Gene Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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