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IQGAP1 (NM_003870) Human Untagged Clone
CAT＃: SC117725
IQGAP1 (untagged)-Human IQ motif containing GTPase activating protein 1 (IQGAP1)
CNY 11,344.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HUMORFA01; p195; SAR1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003870 edited
GAATTCGGCACGAGCTCAGCAGAGACTCGGGCTCGTCCGCCATGTCCGCCGCAGACGAGG TTGACGGGCTGGGCGTGGCCCGGCCGCACTATGGCTCTGTCCTGGATAATGAAAGACTTA CTGCAGAGGAGATGGATGAAAGGAGACGTCAGAACGTGGCTTATGAGTACCTTTGTCATT TGGAAGAAGCGAAGAGGTGGATGGAAGCATGCCTAGGGGAAGATCTGCCTCCCACCACAG AACTGGAGGAGGGGCTTAGGAATGGGGTCTACCTTGCCAAACTGGGGAACTTCTTCTCTC CCAAAGTAGTGTCCCTGAAAAAAATCTATGATCGAGAACAGACCAGATACAAGGCGACTG GCCTCCACTTTAGACACACTGATAATGTGATTCAGTGGTTGAATGCCATGGATGAGATTG GATTGCCTAAGATTTTTTACCCAGAAACTACAGATATCTATGATCGAAAGAACATGCCAA GATGTATCTACTGTATCCATGCACTCAGTTTGTACCTGTTCAAGCTAGGCCTGGCCCCTC AGATTCAAGACCTATATGGAAAGGTTGACTTCACAGAAGAAGAAATCAACAACATGAAGA CTGAGTTGGAGAAGTATGGCATCCAGATGCCTGCCTTTAGCAAGATTGGGGGCATCTTGG CTAATGAACTGTCAGTGGATGAAGCCGCATTACATGCTGCTGTTATTGCTATTAATGAAG CTATTGACCGTAGAATTCCAGCCGACACATTTGCAGCTTTGAAAAATCCGAATGCCATGC TTGTAAATCTTGAAGAGCCCTTGGCATCCACTTACCAGGATATACTTTACCAGGCTAAGC AGGACAAAATGACAAATGCTAAAAACAGGACAGAAAACTCAGAGAGAGAAAGAGATGTTT ATGAGGAGCTGCTCACGCAAGCTGAAATTCAAGGCAATATAAACAAAGTCAATACATTTT CTGCATTAGCAAATATCGACCTGGCTTTAGAACAAGGAGATGCACTGGCCTTGTTCAGGG CTCTGCAGTCACCAGCCCTGGGGCTTCGAGGACTGCAGCAACAGAATAGCGACTGGTACT TGAAGCAGCTCCTGAGTGATAAACAGCAGAAGAGACAGAGTGGTCAGACTGACCCCCTGC AGAAGGAGGAGCTGCAGTCTGGAGTGGATGCTGCAAACAGTGCTGCCCAGCAATATCAGA GAAGATTGGCAGCAGTAGCACTGATTAATGCTGCAATCCAGAAGGGTGTTGCTGAGAAGA CTGTTTTGGAACTGATGAATCCCGAAGCCCAGCTGCCCCAGGTGTATCCATTTGCCGCCG ATCTCTATCAGAAGGAGCTGGCTACCCTGCAGCGACAAAGTCCTGAACATAATCTCACCC ACCCAGAGCTCTCTGTCGCAGTGGAGATGTTGTCATCGGTGGCCCTGATCAACAGGGCAT TGGAATCAGGAGATGTGAATACAGTGTGGAAGCAATTGAGCAGTTCAGTTACTGGTCTTA CCAATATTGAGGAAGAAAACTGTCAGAGGTATCTCGATGAGTTGATGAAACTGAAGGCTC AGGCACATGCAGAGAATAATGAATTCATTACATGGAATGATATCCAAGCTTGCGTGGACC ATGTGAACCTGGTGGTGCAAGAGGAACATGAGAGGATTTTAGCCATTGGTTTAATTAATG AAGCCCTGGATGAAGGTGATGCCCAAAAGACTCTGCAGGCCCTACAGATTCCTGCAGCTA AACTTGAGGGAGTCCTTGCAGAAGTGGCCCAGCATTACCAAGACACGCTGATTAGAGCGA AGAGAGAGAAAGCCCAGGAAATCCAGGATGAGTCAGCTGTGTTATGGTTGGATGAAATTC AAGGTGGAATCTGGCAGTCCAACAAAGACACCCAAGAAGCACAGAAGTTTGCCTTAGGAA TCTTTGCCATTAATGAGGCAGTAGAAAGTGGTGATGTTGGCAAAACACTGAGTGCCCTTC GCTCCCCTGATGTTGGCTTGTATGGAGTCATCCCTGAGTGTGGTGAAACTTACCACAGTG ATCTTGCTGAAGCCAAGAAGAAAAAACTGGCAGTAGGAGATAATAACAGCAAGTGGGTGA AGCACTGGGTAAAAGGTGGATATTATTATTACCACAATCTGGAGACCCAGGAAGGAGGAT GGGATGAACCCCCAAATTTTGTGCAAAATTCTATGCAGCTTTCTCGGGAGGAGATCCAGA GTTCTATCTCTGGGGTGACTGCCGCATATAACCGAGAACAGCTGTGGCTGGCCAATGAAG GCCTGATCACCAGGCTGCAGGCTCGCTGCCGTGGATACTTAGTTCGACAGGAATTCCGAT CCAGGATGAATTTCCTGAAGAAACAAATCCCTGCCATCACCTGCATTCAGTCACAGTGGA GAGGATACAAGCAGAAGAAGGCATATCAAGATCGGTTAGCTTACCTGCGCTCCCACAAAG ATGAAGTTGTAAAGATTCAGTCCCTGGCAAGGATGCACCAAGCTCGAAAGCGCTATCGAG ATCGCCTGCAGTACTTCCGGGACCATATAAATGACATTATCAAAATCCAGGCTTTTATTC GGGCAAACAAAGCTCGGGATGACTACAAGACTCTCATCAATGCTGAGGATCCTCCTATGG TTGTGGTCCGAAAATTTGTCCACCTGCTGGACCAAAGTGACCAGGATTTTCAGGAGGAGC TTGACCTTATGAAGATGCGGGAAGAGGTTATCACCCTCATTCGTTCTAACCAGCAGCTGG AGAATGACCTCAATCTCATGGATATCAAAATTGGACTGCTAGTGAAAAATAAGATTACGT TGCAGGATGTGGTTTCCCACAGTAAAAAACTTACCAAAAAAAATAAGGAACAGTTGTCTG ATATGATGATGATAAATAAACAGAAGGGAGGTCTCAAGGCTTTGAGCAAGGAGAAGAGAG AGAAGTTGGAAGCTTACCAGCACCTGTTTTATTTATTGCAAACCAATCCCACCTATCTGG CCAAGCTCATTTTTCAGATGCCCCAGAACAAGTCCACCAAGTTCATGGACTCTGTAATCT TCACACTCTACAACTACGCGTCCAACCAGCGAGAGGAGTACCTGCTCCTGCGGCTCTTTA AGACAGCACTCCAAGAGGAAATCAAGTCGAAGGTAGATCAGATTCAAGAGATTGTGACAG GAAATCCTACGGTTATTAAAATGGTTGTAAGTTTCAACCGTGGTGCCCGTGGCCAGAATG CCCTGAGACAGATCTTGGCCCCAGTCGTGAAGGAAATTATGGATGACAAATCTCTCAACA TCAAAACTGACCCTGTGGATATTTACAAATCTTGGGTTAATCAGATGGAGTCTCAGACAG GAGAGGCAAGCAAACTGCCCTATGATGTGACCCCTGAGCAGGCGCTAGCTCATGAAGAAG TGAAGACACGGCTAGACAGCTCCATCAGGAACATGCGGGCTGTGACAGACAAGTTTCTCT CAGCCATTGTCAGCTCTGTGGACAAAATCCCTTATGGGATGCGCTTCATTGCCAAAGTGC TGAAGGACTCGTTGCATGAGAAGTTCCCTGATGCTGGTGAGGATGAGCTGCTGAAGATTA TTGGTAACTTGCTTTATTATCGATACATGAATCCAGCCATTGTTGCTCCTGATGCCTTTG ACATCATTGACCTGTCAGCAGGAGGCCAGCTTACCACAGACCAACGCCGAAATCTGGGCT CCATTGCAAAAATGCTTCAGCATGCTGCTTCCAATAAGATGTTTCTGGGAGATAATGCCC ACTTAAGCATCATTAATGAATATCTTTCCCAGTCCTACCAGAAATTCAGACGGTTTTTCC AAACTGCTTGTGATGTCCCAGAGCTTCAGGATAAATTTAATGTGGATGAGTACTCTGATT TAGTAACCCTCACCAAACCAGTAATCTACATTTCCATTGGTGAAATCATCAACACCCACA CTCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCACGAAC TGCTGGACGACCTCGGCGAGGTGCCCACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCA ATTTAAATGACCCAAATAAGGAGGCACTGGCTAAGACGGAAGTGTCTCTCACCCTGACCA ACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTTACTGA ATACAAAACGTTTAATTGTGGATGTCATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAA TCCTAGAAACACCAGCCACCAGTGAACAGGAAGCAGAACATCAGAGAGCCATGCAGAGAC GTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAAGGAAG ACAGCAACCTCACTCTTCAAGAGAAGAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAA CAGAGCTTGGAACCGTGGACCCAAAGAACAAATACCAGGAACTGATCAACGACATTGCCA GGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAAACTGC AACAGACATACGCTGCTCTGAACTCTAAGGCCACCTTTTATGGGGAGCAGGTGGATTACT ATAAAAGCTATATCAAAACCTGCTTGGATAACTTAGCCAGCAAGGGCAAAGTCTCCAAAA AGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGCAGCAA GACTACATGAAAAAGGAGTTCTTCTGGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAA ATGTTATATTTGAAATCAGTCCAACAGAAGAAGTTGGAGACTTCGAAGTGAAAGCCAAAT TCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCTACAGT ATGAAGGAGTTGCAGTCATGAAATTATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGA TCTTCCTTCTCAACAAAAAGTTCTACGGGAAGTAATTGATCGTTTGCTGCCAGCCCAGAA GXXXXXXXXXXXXXXXXXXXXXXXXXXTAAAGTATAGATGTATGTCTTAAAATGTGGGTG ATAGGAATTTTAAAGATTTATATAATGCATCAAAAGCCTTAGAATAAGAAAAGCTTTTTT TAAATTGCTTTATCTGTATATCTGAACTCTTGAAACTTATAGCTAAAACAATAGGATTTA TCTGCAGTGTTGCAGGGAGATAATTCTGCCTTAAATTGTCTAAAACAAAAACAAAACCAG CCAACCTATGTTACACGTGAGATTAAAACCAATTTTTTCCCCATTTTTTTTCCTTTTTTC TCTTGCTGCCCACATTGTGCCTTTATTTTATGAGCCCCAGTTTTTTGGGCTTAGTTTAAA AAAAAAATCAAGTCTAAACATTGCATTTAGAAAGCTTTTGTTCTTGGATAAAAAGTCATA CACTTTAAAAAAAAAAAAAACTTTTTCCAGGAAAATATATTGAAATCATGCTGCTGAGCC TCTATTTTCTTTCTTTGATGTTTTGATTCAGTATTCTTTTATCATAAATTTTTAGCATTT AAAAATTCACTGATGTACATTAAGCCAATAAACTGCTTTAATGAATAACAAAAAAAAAAA AAAAAAAACTCGAC >OriGene 5' read for NM_003870 unedited
TTCAAATTATGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGCTCAGCAG AGACTCGGGCTCGTCCGCCATGTCCGCCGCAGACGAGGTTGACGGGCTGGGCGTGGCCCG GCCGCACTATGGCTCTGTCCTGGATAATGAAAGACTTACTGCAGAGGAGATGGATGAAAG GAGACGTCAGAACGTGGCTTATGAGTACCTTTGTCATTTGGAAGAAGCGAAGAGGTGGAT GGAAGCATGCCTAGGGGAAGATCTGCCTCCCACCACAGAACTGGAGGAGGGGCTTAGGAA TGGGGTCTACCTTGCCAAACTGGGGAACTTCTTCTCTCCCAAAGTAGTGTCCCTGAAAAA AATCTATGATCGAGAACAGACCAGATACAAGGCGACTGGCCTCCACTTTAGACACACTGA TAATGTGATTCAGTGGTTGAATGCCATGGATGAGATTGGATTGCCTAAGATTTTTTACCC AGAAACTACAGATATCTATGATCGAAAGAACATGCCAAGATGTATCTACTGTATCCATGC ACTCAGTTTGTACCTGTTCAAGCTAGGCCTGGCCCCTCAGATTCAAGACCTATATGGAAA GGTTGACTTCACAGAAGAAGAAATCAACAACATGAAGACTGAGTTGGAGAAGTATGGCAT CCAGATGCCTGCCTTTAGCAAGATTGGGGGCATCTTGGCTAATGAACTGTCAGTGGATGA AGCCGCATTACATGCTGCTGTTATTGCTATTAATGAAGCTATTGACCGTAGAATTCCAGC CGACACATTTGCAGCTTTGAAAAATCCGAATGCCATGCTTGNTAATCTTGAAGAGCCCTT GGCATNCACTTACCAGNATATACTNNTACCAGNNCTAGCAGACANNATGACAATGCTAAA ACAGGACAGAAACTCAGAGAGAGAAAGAGAGTTNATGAGGAGCTGCTCCGC >OriGene 3' read for NM_003870 unedited
CTGCAATTACTTGCACCCGGCCGCAATCTACGAGCGACTTTTTTTTTTTTTTTTTTTGTT ATTCATTAAAGCAGTTTATTGGCTTACAGTACATCAGTGAATTTTTAAATGCTAAAAATT TATGATAAAAGAATACTGAATCAAAACATCAAAGAAAGAAAATAGAGGCTCAGCAGCATG ATTTCAATATATTTTCCTGGAAAAAGTTTTTTTTTTTTTTAAAGTGTATGACTTTTTATC CAAGAACAAAAGCTTTCTAAATGCAATGTTTAGACTTGATTTTTTTTTTAAACTAAGCCC AGAAAACTGGGGCTCATAAAATAAAGGCACAATGTGGGCAGCAAGACAAAAAAGGAGAAA AAATGGGGAAAAAATTGGCTTTAATCTCACGTGTAACATAGGTTGGCTGGTTTTGTTTTT GTTTTAGACAATTTAAGGCAGAATTATCTCCCTGCAACACTGCAGATAAATCCTAGTGTT TTAGCTATAAGTTTCAAGAGTTCAGATATACAGATAAAGCAATTTAAAAAAAGCTTTTCT TATTCTAAGGCTTTTGATGCATTATATAAATTTTTAAAATTCCTATCACCCACATTTTAA GACCTACATCTATACTTTAATAAGGCACTCTTAAGACATAAAACCGCTTTAAAAACAATG ACATTCTACACTAGGGCTAACCCATTCCTCTGCCCTAGGGATGGAGTGAACTGCCTCTCT GAATAAGCCACACTTCTGTGCACCAACACCAACCGGCCGGTGCCCTGACCCACTCTGAAC TTACCTGATCACCTTCACTTTAACACTGGGCCTCTCCCAACCCTACCCGGGGAGCTCCCC CACCCCAACTCCCCTATTTGACAATGAACACCACCCCCTTCTTTCTTTTTTCTAAACACG TTTCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003870 |
| Insert Size | 6500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003870.3, NP_003861.1 |
| RefSeq Size | 7219 bp |
| RefSeq ORF | 4974 bp |
| Locus ID | 8826 |
| UniProt ID | P46940 |
| Domains | IQ, RasGAP_C, WW, CH, RasGAP |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Regulation of actin cytoskeleton |
| Gene Summary | This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Bile Acids Activate YAP to Promote Liver Carcinogenesis
,Anakk, S;Bhosale, M;Schmidt, VA;Johnson, RL;Finegold, MJ;Moore, DD;,
Cell Rep
,PubMed ID 24268772
[Iqgap1]
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| RC218549L1 | Lenti ORF clone of Human IQ motif containing GTPase activating protein 1 (IQGAP1), Myc-DDK-tagged |
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| RC218549L2 | Lenti ORF clone of Human IQ motif containing GTPase activating protein 1 (IQGAP1), mGFP tagged |
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| RC218549L3 | Lenti ORF clone of Human IQ motif containing GTPase activating protein 1 (IQGAP1), Myc-DDK-tagged |
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| RC218549L4 | Lenti ORF clone of Human IQ motif containing GTPase activating protein 1 (IQGAP1), mGFP tagged |
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| RG218549 | IQGAP1 (tGFP-tagged) - Human IQ motif containing GTPase activating protein 1 (IQGAP1) |
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