United States
Germany
Japan
United Kingdom
China
APPBP1 (NAE1) (NM_003905) Human Untagged Clone
CAT＃: SC117674
NAE1 (untagged)-Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | A-116A10.1; APPBP1; HPP1; ula-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117674 sequence for NM_003905 edited (data generated by NextGen Sequencing)
ATGGCGCAGCTGGGAAAGCTGCTCAAGGAGCAGAAGTACGACCGGCAGCTGAGGTTGTGG GGTGATCATGGGCAAGAGGCTTTAGAATCTGCTCATGTTTGCCTAATAAATGCAACAGCC ACAGGAACTGAAATTCTTAAAAACTTGGTACTACCAGGTATTGGTTCGTTTACAATTATT GATGGAAATCAGGTCAGCGGAGAAGATGCTGGAAACAATTTCTTCCTTCAAAGAAGCAGT ATCGGCAAGAACCGAGCTGAAGCTGCCATGGAATTCTTACAAGAATTAAATAGCGATGTC TCTGGAAGTTTTGTGGAAGAGAGTCCAGAAAACCTTCTAGACAATGATCCCTCATTTTTC TGTAGGTTTACTGTTGTAGTTGCAACTCAGCTTCCTGAAAGCACTTCACTACGCTTAGCA GATGTCCTCTGGAATTCCCAGATTCCTCTTTTGATCTGTAGGACATATGGACTAGTTGGT TATATGAGGATCATTATAAAAGAACATCCAGTAATAGAATCTCATCCAGATAATGCATTA GAGGATCTACGACTAGATAAGCCATTTCCTGAACTGAGAGAACATTTTCAGTCCTATGAT TTGGATCATATGGAAAAAAAGGACCACAGTCATACTCCATGGATTGTGATCATAGCTAAA TATTTAGCACAGTGGTATAGTGAAACAAATGGACGAATACCTAAAACGTATAAAGAAAAA GAGGACTTCAGAGATTTGATTAGACAAGGAATTCTAAAAAATGAAAATGGGGCTCCAGAA GATGAAGAGAATTTTGAAGAAGCTATTAAAAATGTGAACACAGCACTAAATACAACTCAG ATCCCAAGCAGTATTGAAGATATATTTAATGATGATCGCTGCATAAATATCACCAAACAG ACTCCATCATTTTGGATTTTAGCTCGTGCCTTAAAGGAATTTGTGGCCAAAGAGGGTCAA GGAAATTTACCTGTTCGAGGCACAATTCCTGATATGATTGCAGATTCAGGCAAATATATA AAACTGCAAAACGTTTACCGTGAAAAAGCAAAGAAAGATGCTGCCGCTGTGGGTAATCAT GTTGCCAAATTGCTGCAGTCCATTGGCCAGGCACCAGAGTCCATTTCAGAGAAAGAATTA AAATTACTCTGCAGCAATTCTGCATTTCTTCGAGTGGTAAGATGTCGATCCTTAGCTGAA GAATATGGTTTGGATACAATTAACAAGGATGAAATTATTTCTAGCATGGACAATCCAGAT AATGAAATAGTGTTGTACTTAATGTTACGGGCTGTTGATAGATTTCATAAACAACAGGGT AGATATCCAGGAGTATCTAACTATCAAGTTGAAGAAGATATAGGAAAGTTGAAGTCTTGT CTCACTGGCTTCCTTCAGGAATATGGTTTATCTGTAATGGTGAAAGATGATTATGTCCAC GAATTTTGCCGATATGGAGCTGCTGAGCCACATACCATTGCTGCATTCTTGGGGGGAGCT GCTGCTCAAGAGGTCATCAAAATAATCACCAAACAATTTGTAATTTTTAATAATACTTAC ATTTACAGTGGCATGTCACAAACTTCAGCAACTTTCCAGTTGTAG Clone variation with respect to NM_003905.3 >OriGene 5' read for NM_003905 unedited
TGCGNCATATTTGGAATACCCATTCACTCATAGGGCGCGCCGCGCAATTCGGCACGAGGG CTCCGCAGGGCTCGGCTGTTTTCCGCGCGGCAGGCGCGGCCATGGCGCACCTGGGAAAGC TGCTCAAGGAGCAGAAGTACGACCGGCAGCTGAGGTTGTGGGGTGATCATGGGCAAGAGG CTTTAGAATCTGCTCATGTTTGCCTAATAAATGCAACTTTTCCAGGAACTGAAATTCTTA AAAACTTGGGACTACCAGGTATTGGCTCGTTTACAATTATTGATGGAAATCAGGTCAGCG GAGAAGATGCTGGAAACAATTTCTTCCTTCAAAGAAGCAGTATCGGCAAGAACCGAGCTG AAGCTGCCATGGAATTCTTACAAGAATTAAATAGCGATGTCTCTGGAAGTTTTGTGGAAG AGAGTCCAGAAAACCTTCTAGACAATGATCCCTCATTTTTCTGTAGGTTTACTGTTGTAG TTGCAACTCAGCTTCCTGAAAGCACTTCACTACGCTTAGCAGATGTCCTCTGGAATTCCC AGATTCCTCTTTTGATCTGTAGGACATATGGACTAGTTGGTTATATGAGGATCATTATAA AAGAACATCCAGTAATAGAATCTCATCCAGATAATGCATTAGAGGATCTACGACTAGATA AGCCATTTCCTGAACTGAGAGAACATTTTCAGTCCTATGATTGGGATCATATGGAAAAAA AGGACCACAGTCATACTCCATGGATTGTGATCATAGCTAAATATTTAGCACAGTGGTATA GTGAAACAAATGGACGAATTCCTTAAACGTACTAAGAACAAGAGGACTTCCCAGATTTGA TTAGACAAGGAACTCCTAAAAATGAAAACGGGGCTCCAGAGAATGAAAAGAATTTTGAAA AACTATTAAAAATGGGAACCCAGCCCTAAATACAACTCAN >OriGene 3' read for NM_003905 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCAAATGAGAAAAATGTTTATTAA GAAAACAATTTAGCAGCTCTCCTTTAGAATTTTACAGACTAAAGCACAACCCGAAGGCAA TTACAGTTTCAATCATTAACACACTACTTAAGGTGCTTGCTTACTCTACAACTGGAAAGT TGCTGAAGTTTGTGACATGCCACTGTAAATGTAAGTATTATTAAAAATTACAAATTGTTT GGTGATTATTTTGATGACCTCTTGAGCAGCAGCTCCCCCCAAGAATGCAGCAATGGTATG TGGCTCAGCAGCTCCATATCGGCAAAATTCGTGGACATAATCATCTTTCACCATTACAGA TAAACCATATTCCTGAAGGAAGCCAGTGAGACAAGACTTCAACTTTCCTATATCTTCTTC AACTTGATAGTTAGATACTCCTGGATATCTACCCTGTTGTTTATGAAATCTATCAACAGC CCGTAACATTAAGTACAACACTATTTCATTATCTGGATTGTCCATGCTAGAAATAATTTC ATCCTTGTTAATTGTATCCAAACCATATTCTTCAGCTAAGGATCGACATCTTACCACTCG AAGAAATGCAGAATTGCTGCAGAGTAATTNTAATTCTTTCTCTGAAATGGACTCTGGTGC CTGGCCAATGGACTGCAGCAATTTGGCAACATGATTACCCACAGCGGCAGCATCTTTCTT TGCTTTTTACGGTAAACGTTNTGCAGTTTTATATATTTGCCTGAATCTGNCATCATATCA NGAATTGTGCCTCNGACAGGTAAAATTCCCTTGACCCTCTTNTGCCCNNAATCCTTTANG CACGAGCTAAAATCCAATGATGGAGTCTGTTTGGTGATATTATGCAGCGATCATCATTAA TATATCTCATACTGNCTGGNATCTGAGTTGNATTTAAGGCTGNGTTCACATTTTAATAGC TCTTCAAAATCTCTCTCTNTCTGGACCCCATTTCATTNTTAGATNCCTGNCTATCAATCC CT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003905 |
| Insert Size | 1950 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003905.3, NP_003896.1 |
| RefSeq Size | 1820 bp |
| RefSeq ORF | 1605 bp |
| Locus ID | 8883 |
| UniProt ID | Q13564 |
| Domains | ThiF |
| Protein Pathways | Alzheimer's disease |
| Gene Summary | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the predominant isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213781 | NAE1 (Myc-DDK-tagged)-Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1 |
CNY 3,976.00 |
|
| RC213781L1 | Lenti ORF clone of Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1, Myc-DDK-tagged |
CNY 6,376.00 |
|
| RC213781L2 | Lenti ORF clone of Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC213781L3 | Lenti ORF clone of Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC213781L4 | Lenti ORF clone of Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RG213781 | NAE1 (tGFP-tagged) - Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1 |
CNY 5,040.00 |
