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PSTPIP1 (NM_003978) Human Untagged Clone
CAT＃: SC117638
PSTPIP1 (untagged)-Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD2BP1; CD2BP1L; CD2BP1S; H-PIP; PAPAS; PSTPIP |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003978, the custom clone sequence may differ by one or more nucleotides
ATGATGCCCCAGCTGCAGTTCAAAGATGCCTTTTGGTGCAGGGACTTCACAGCCCACACGGGCTACGAGG TGCTGCTGCAGCGGCTTCTGGATGGCAGGAAGATGTGCAAAGACATGGAGGAGCTACTGAGGCAGAGGGC CCAGGCGGAGGAGCGGTACGGGAAGGAGCTGGTGCAGATCGCACGGAAGGCAGGTGGCCAGACGGAGATC AACTCCCTGAGGGCCTCCTTTGACTCCTTGAAGCAGCAAATGGAGAATGTGGGCAGCTCACACATCCAGC TGGCCCTGACCCTGCGTGAGGAGCTGCGGAGTCTCGAGGAGTTTCGTGAGAGGCAGAAGGAGCAGAGGAA GAAGTATGAGGCCGTCATGGACCGGGTCCAGAAGAGCAAGCTGTCGCTCTACAAGAAGGCCATGGAGTCC AAGAAGACATACGAGCAGAAGTGCCGGGACGCGGACGACGCGGAGCAGGCCTTCGAGCGCATTAGCGCCA ACGGCCACCAGAAGCAGGTGGAGAAGAGTCAGAACAAAGCCAGGCAGTGCAAGGACTCGGCCACCGAGGC AGAGCGGGTATACAGGCAGAGCATTGCGCAGCTGGAGAAGGTCCGGGCTGAGTGGGAGCAGGAGCACCGG ACCACCTGTGAGGCCTTTCAGCTGCAAGAGTTTGACCGGCTGACCATTCTCCGCAACGCCCTGTGGGTGC ACAGCAACCAGCTCTCCATGCAGTGTGTCAAGGATGATGAGCTCTACGAGGAAGTGCGGCTGACGCTGGA AGGCTGCAGCATAGACGCCGACATCGACAGTTTCATCCAGGCCAAGAGCACGGGCACAGAGCCCCCCGCT CCGGTGCCCTACCAGAACTATTACGATCGGGAGGTCACCCCGCTGACCAGCAGCCCTGGCATACAGCCGT CCTGCGGCATGATAAAGAGGTTCTCTGGACTGCTGCACGGAAGTCCCAAGACCACTTCGTTGGCAGCTTC TGCTGCGTCCACAGAGACCCTGACCCCCACCCCCGAGCGGAATGAGGGTGTCTACACAGCCATCGCAGTG CAGGAGATACAGGGAAACCCGGCCTCACCAGCCCAGGAGTACCGGGCGCTCTACGATTATACAGCGCAGA ACCCAGATGAGCTGGACCTGTCCGCGGGAGACATCCTGGAGGTGATCCTGGAAGGGGAGGATGGCTGGTG GACTGTGGAGAGGAACGGGCAGCGTGGCTTCGTCCCTGGTTCCTACCTGGAGAAGCTTTGA >OriGene 5' read for NM_003978 unedited
AGGATTTTGTAATACGACTTACTTATAGGGCGGCCGCGAATTCGCACGAGCATGGCCCTT CATCCGGGGCTGCCCTGGCTGGACAGCCCCCCAGAGCACAGCTGTGTCTGCTCCCAGACT ATGGGCTCCTTGAGGGCAGGACCTGGTTTGGGTCCCAGAGCAGCCAGGGTTTGATGAATG ACAGATGCCCTAGACCTGGAAGCTCCTCTCTGGCTCGTGGCTGCCTTCTGAGTGTTGCAG ACGGCGCCGGCCGGGAAGGGGGGCCTGGGCCAGCCCTGCCAGGACTGGGACGCTGCTGCT GGCGCCTGGCCCTCCATCAGGCCAGCCTGTGGCAGGAGAGTGAGCTTTGCCGCGGCAGAC GCCTGAGGATGATGCCCCAGCTGCAGTTCAAAGATGCCTTTTGGTGCAGGGACTTCACAG CCCACACGGGCTACGAGGTGCTGCTGCAGCGGCTTCTGGATGGCAGGAAGATGTGCAAAG ACATGGAGGAGCTACTGAGGCAGAGGGCCCAGGCGGAGGAGCGGTACGGGAAGGAGCTGG TGCAGATCGCACGGAAGGCAGGTGGCCAGACGGAGATCAACTCCCTGAGGGCCTCCTTTG ACTCCTTGAAGCAGCAAATGGAGAATGTGGGCAGCTCACACATCCAGCTGGCCCTGACCC TGCGTGAGGAGCTGCGGAGTCTCGAGGAGTTTCGTGAGAGGCAGAAGGAGCAGAGGAAGA AGTATGAGGCCGTCATGGACCGGGTCCAGAAGAGCAAGCTGTCGCTCTANCAGAAGCCAT GGAGTCCAAGAAGAATACGAGCANAAGTGCCGGGACGCGGACGACGNCGNAGCAGCCTTC GAGCGCATTAGCGCCAACGGNCACCAGAAAGCAGTGGAGAAGAGTCAGAACAAGCCCAGC AGTGCAAGTACTTCGNCCACCGAGCAGAGCGGGTATACAGNCANAGCATGCGCACTTGGA GAAAGTCCGGCCTGANTGGGAGCAGNAGNACCGTACCT >OriGene 3' read for NM_003978 unedited
CGGGCCCCCCCCACCCTCCTTCCCCCNNCGGNAATGGTGAACCCGGCCGCATTTTANGAT CGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAACAAAA CGCACTCCTTTATTCCCTGGGGAAACCACAGGCTCCCTTTTGGGGCTGGGGGACCCTTGG TTTTGGGCCCTCACAAGGGGGGACAGTGCTGGGGGCACTGCTGGCTCCACTGGCAGGGCA GGTCCCAAGGGGCTCCTGGCCCTTCCTCAAAGCTTTTCCAGGTAGGAACCAGGGACCAAA CCCCCCTGCCCGTTCCTTTCCACAGTCCACCAGCCATTCTCCCCTTTCAGGAACACCTCC AGGATGTCTCCCGCGGACAGGGCCAACTCATTTGGGTTCTGCCCTGTATAATCGTAAAGC GCCCGGGACTCCTGGGCTGGGGAGGCCCGGTTTCCCTGTATCTCCTGCACTGGGATGGCT GGGTAAACACCCTTATTCCCCTCGGGGGTGGGGGGCAGGGTCTTAACAAAAACTGCCAAC CAAAGGGTCTTGGGACTTCCGGGACAAAACCAAAAAACCTTTTTTTATGCCCCAGGAACG GTGTTTCCACGGCTGTTTGTCACCGGGGGGAACCTCCCAACGTAAAAATTTTTGGAAGGC ACCCGGAACCGGGGGCCCTTGGGCCCCCGCCTTTGGGCCCTGAAAAAAATGTCCAATGTC GGCGGTTTTTTCTTGAAACCTTTTCAAGGTGAAGCCCCACTTTCCCTGAAAAAGTTTTAT ATCTCTGACCCACATTTATTGAAAAACTTTTTTCTTTGGCCCCCCACAGGGCCTTTCCGG AAAAAGGGAAACCCGGCCAAACTTTTTGTACTTAGAAGGGCTCCACAGGGGGGTCCGGTG TTTTTTGTTTCCCATATAAACCGGGACTCTTTTACAAATGGGCAAAGGTTTTGGTCTTGT AACCCCCTTTTTGCCTGGGGGGCCGAACCCTTCCACACGCCTGGGTTTTTTTCGACACTT TTTCCCCGGCTCTTGTGGGGCCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003978 |
| Insert Size | 1830 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003978.2, NP_003969.2 |
| RefSeq Size | 1781 bp |
| RefSeq ORF | 1251 bp |
| Locus ID | 9051 |
| UniProt ID | O43586 |
| Domains | FCH, SH3 |
| Protein Families | Druggable Genome |
| Protein Pathways | NOD-like receptor signaling pathway |
| Gene Summary | This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response. [provided by RefSeq, Mar 2016] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203788 | PSTPIP1 (Myc-DDK-tagged)-Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1) |
CNY 3,656.00 |
|
| RC203788L1 | Lenti ORF clone of Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203788L2 | Lenti ORF clone of Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), mGFP tagged |
CNY 5,890.00 |
|
| RC203788L3 | Lenti ORF clone of Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203788L4 | Lenti ORF clone of Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), mGFP tagged |
CNY 5,890.00 |
|
| RG203788 | PSTPIP1 (tGFP-tagged) - Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1) |
CNY 5,256.00 |
|
| SC322259 | PSTPIP1 (untagged)-Human proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1) |
CNY 3,656.00 |
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