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CA8 (NM_004056) Human Untagged Clone
CAT＃: SC117603
CA8 (untagged)-Human carbonic anhydrase VIII (CA8)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CA-RP; CA-VIII; CALS; CAMRQ3; CARP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117603 sequence for NM_004056 edited (data generated by NextGen Sequencing)
ATGGCGGACCTGAGCTTCATCGAAGATACCGTCGCCTTCCCCGAGAAGGAAGAGGATGAG GAGGAAGAAGAGGAGGGTGTGGAGTGGGGCTACGAGGAAGGTGTTGAGTGGGGTCTGGTG TTTCCTGATGCTAATGGGGAATACCAGTCTCCTATTAACCTAAACTCAAGAGAGGCTAGG TATGACCCCTCGCTGTTGGATGTCCGCCTCTCCCCAAATTATGTGGTGTGCCGAGACTGT GAAGTCACCAATGATGGACATACCATTCAGGTTATCCTGAAGTCAAAATCAGTTCTTTCG GGAGGACCATTGCCTCAAGGGCATGAGTTTGAACTGTACGAAGTGAGATTTCACTGGGGA AGAGAAAACCAGCGTGGTTCTGAGCACACGGTTAATTTCAAAGCTTTTCCCATGGAGCTC CATCTGATCCACTGGAACTCCACTCTGTTTGGCAGCATTGATGAGGCTGTGGGGAAGCCG CACGGAATCGCCATCATTGCTCTGTTTGTTCAGATAGGAAAGGAACATGTTGGCTTGAAG GCTGTGACTGAAATCCTCCAAGATATTCAGTATAAGGGGAAGTCCAAAACAATACCTTGC TTTAATCCTAACACTTTATTACCAGACCCTCTGCTGCGGGATTACTGGGTGTATGAAGGC TCTCTCACCATCCCACCTTGCAGTGAAGGTGTCACCTGGATATTATTCCGATACCCTTTA ACTATATCCCAGCTACAGATAGAAGAATTTCGAAGGCTGAGGACACATGTTAAGGGGGCA GAACTTGTGGAAGGCTGTGATGGGATTTTGGGAGACAACTTTCGGCCCACTCAGCCTCTT AGTGACAGAGTCATTAGAGCTGCATTTCAGTAG Clone variation with respect to NM_004056.4 327 a=>g >OriGene 5' read for NM_004056 unedited
ATTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGTCGCTCTGCTGGG GCCTCCGGACGCGCTTCCCAGCGGGTCTCTGGAACACTCGGTCCGAACGCACGCCTGCTT GCACTCACACTGCGGTTCACACCCGCAGGCGCTCTCGCACCCACACTGCCGCTCACGCGC GCTCACACTCCCCCACGCGCGCTCCGCTCCGGCTCCAGCCCCGCGCCCCGCGAAGGCGCA GGCACTGCTGCCGAGAGCGCCGAGGGGCCCCGCGGCCTTCCCATGGCGGACCTGAGCTTC ATCGAAGATACCGTCGCCTTCCCCGAGAAGGAAGAGGATGAGGAGGAAGAAGAGGAGGGT GTGGAGTGGGGCTACGAGGAAGGTGTTGAGTGGGGTCTGGTGTTTCCTGATGCTAATGGG GAATACCAGTCTCCTATTAACCTAAACTCAAGAGAGGCTAGGTATGACCCCTCGCTGTTG GATGTCCGCCTCTCCCCAAATTATGTGGTGTGCCGAGACTGTGAAGTCACCAATGATGGA CATACCATTCAGGTTATCCTGAAGTCAAAATCAGTTCTTTCGGGAGGACCATTGCCTCAA GGGCATGAGTTTGAACTGTACGAAGTGAGATTTCACTGGGGAAGAGAAAACCAGCGTGGT TCTGAGCACACGGTTAATTTCAAAGCTTTTCCCATGGAGCTCCATCTGATCCACTGGAAC TCCACTCTGTTTGGCAGCATTGATGAGGCTGTGGGGAAGCCGCACGGAATCGCCATCATT GCTCTGTTTGTTCAGATAGGAAAGAACATGTTNNGCTGAGGCTGTGACTGANATCCTCCA AGAATTCAGTATAAGGGGGAAGTCCAAACAATACCTTGCTTT >OriGene 3' read for NM_004056 unedited
AGCTATGGACCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTCATT TCAGTCTTTTACTCAAAAAATATACAGTAAATAAATTCAAATTGCTTCAATATACAGACA TAAACACACATACACACACACCTGTGAAGGGTGAAGTCTGAACAACTAGATGTTATCCTG AAAGTCATTTAATTACTATTTGTTATTGTATTTGTTTATTTTGTGTATTTCAGGGAAAGA TGAAAGAAGATTGCAAGAAGCATCAGAAGTCTAGTTCAAGAACAATCCCTGACTGTTCAG CACCAACCCGGTCAGGAGTGGAAAGGCTGGTACCTGTGCAGTGTTTTGTTCCAGGAATGC CATATGAATGGCCTCTCATTTATGGAAGGCTTCAAATCTAGTCTTTTGATGTTAATTACA AATAAGGCTGCACGTGTGCAGCCAATGTTTGGCATGTGAGTGGTAACAGTGCTAGATGTA AATATTTTTGTCACAGTTTTGTAACCATGCTTCACCATTTCCTCATTGTTGGACACTAGG AACTGTTATACATAAGGGAAGTCCAGGACCTCTCTCCGCTTTCAGAGGCACTGCCTGGTG CTGACCCCCATGTGATCCCAGGGCTACCCAACAGATCTCAACCCCTTAGCAAGCCTCAAC TTTTCCACACATTGCCATAACCCTAGTCCTTTCTCTTGCTGCCCAAGAAACATGATGAAC TTTCTTTGCTTGAATTTAGGGATTTCTGGTGTGATTTTCATTTGNATTAAAGGCTCCCAT TATTACCGCCTTTACTCAACAAATCTAANAACTCTGCACATATACTTATTACACCTGTCT TCTATTTCTATGACTTAGATATCTTGCATCACAAAATCCCTCCAACTTGGGCACTATGTT TTTGAAGCCATTCATTTTACAATCTTACATCCATTACCCTATTCTTATTGTGTGCTTTGA G |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004056 |
| Insert Size | 2870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004056.4, NP_004047.3 |
| RefSeq Size | 2278 bp |
| RefSeq ORF | 873 bp |
| Locus ID | 767 |
| UniProt ID | P35219 |
| Domains | carb_anhydrase |
| Protein Families | Druggable Genome |
| Protein Pathways | Nitrogen metabolism |
| Gene Summary | The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth
,Shimobayashi, E;Wagner, W;Kapfhammer, JP;,
Mol. Neurobiol.
,PubMed ID 26399641
[CA8]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210228 | CA8 (Myc-DDK-tagged)-Human carbonic anhydrase VIII (CA8) |
CNY 2,400.00 |
|
| RC210228L1 | Lenti ORF clone of Human carbonic anhydrase VIII (CA8), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210228L2 | Lenti ORF clone of Human carbonic anhydrase VIII (CA8), mGFP tagged |
CNY 5,890.00 |
|
| RC210228L3 | Lenti ORF clone of Human carbonic anhydrase VIII (CA8), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210228L4 | Lenti ORF clone of Human carbonic anhydrase VIII (CA8), mGFP tagged |
CNY 5,890.00 |
|
| RG210228 | CA8 (tGFP-tagged) - Human carbonic anhydrase VIII (CA8) |
CNY 4,370.00 |
