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ERAB (HSD17B10) (NM_004493) Human Untagged Clone
CAT＃: SC117339
HSD17B10 (untagged)-Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; HSD10MD; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD; SDR5C1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117339 sequence for NM_004493 edited (data generated by NextGen Sequencing)
ATGGCAGCAGCGTGTCGGAGCGTGAAGGGCCTGGTGGCGGTAATAACCGGAGGAGCCTCG GGCCTGGGCCTGGCCACGGCGGAGCGACTTGTGGGGCAGGGAGCCTCTGCTGTGCTTCTG GACCTGCCCAACTCGGGTGGGGAGGCCCAAGCCAAGAAGTTAGGAAACAACTGCGTTTTC GCCCCAGCCGACGTGACCTCTGAGAAGGATGTGCAAACAGCTCTGGCTCTAGCAAAAGGA AAGTTTGGCCGTGTGGATGTAGCTGTCAACTGTGCAGGCATCGCGGTGGCTAGCAAGACG TACAACTTAAAGAAGGGCCAGACCCATACCTTGGAAGACTTCCAGCGAGTTCTTGATGTG AATCTCATGGGCACCTTCAATGTGATCCGCCTGGTGGCTGGTGAGATGGGCCAGAATGAA CCAGACCAGGGAGGCCAACGTGGGGTCATCATCAACACTGCCAGTGTGGCTGCCTTCGAG GGTCAGGTTGGACAAGCTGCATACTCTGCTTCCAAGGGGGGAATAGTGGGCATGACACTG CCCATTGCTCGGGATCTGGCTCCCATAGGTATCCGGGTGATGACCATTGCCCCAGGTCTG TTTGGCACCCCACTGCTGACCAGCCTCCCAGAGAAAGTGTGCAACTTCTTGGCCAGCCAA GTGCCCTTCCCTAGCCGACTGGGTGACCCTGCTGAGTATGCTCACCTCGTACAGGCCATC ATCGAGAACCCATTCCTCAATGGAGAGGTCATCCGGCTGGATGGGGCCATTCGTATGCAG CCTTGA Clone variation with respect to NM_004493.2 >OriGene 5' read for NM_004493 unedited
CTTTTCGGATTTGAAACCGACTTCACTATAGGCGGCCCGCGAATCGGCACGAGGCCGGCG ACAAGATGGCAGCAGCGTGTCGGAGCGTGAAGGGCCTGGTGGCGGTAATAACCGGAGGAG CCTCGGGCCTGGGCCTGGCCACGGCGGAGCGACTTGTGGGGCAGGGAGCCTCTGCTGTGC TTCTGGACCTGCCCAACTCGGGTGGGGAGGCCCAAGCCAAGAAGTTAGGAAACAACTGCG TTTTCGCCCCAGCCGACGTGACCTCTGAGAAGGATGTGCAAACAGCTCTGGCTCTAGCAA AAGGAAAGTTTGGCCGTGTGGATGTAGCTGTCAACTGTGCAGGCATCGCGGTGGCTAGCA AGACGTACAACTTAAAGAAGGGCCAGACCCATACCTTGGAAGACTTCCAGCGAGTTCTTG ATGTGAATCTCATGGGCACCTTCAATGTGATCCGCCTGGTGGCTGGTGAGATGGGCCAGA ATGAACCAGACCAGGGAGGCCAACGTGGGGTCATCATCAACACTGCCAGTGTGGCTGCCT TCGAGGGTCAGGTTGGACAAGCTGCATACTCTGCTTCCAAGGGGGGAATAGTGGGCATGA CACTGCCCATTGCTCGGGATCTGGCTCCCATACGTATCCGGGTGATGACCATTGCCCCAG GTAGACATATCCCCTCTCTCCATCATACCTGGGATTGGGTGGGATCCATGGACAGTTGAG AGGGGAAGGTATCCACCACCTAAGCAGCAGCAGCCCTTTATCTTTGGGCCCCAGAGAAGC CCCAGCAGTAGGGCTAACGTACGGAACACCCAGTAATCATGAAACCAAGGTGAAGCTCTG AATTTGCTATATGGTTACGCCTGTTGGCACCCCCTGCTGACAACCCCCAGAGAAGAGGCA AT >OriGene 3' read for NM_004493 unedited
AGAGTCGAGTTTTTTTTTTTTTTTTTTGTGAGAAAAAAGACTTTATTAGGCACAGAGGGC GACTGGTAGGCAGTTACAAAATGGCTACTGGGCTTCCTCCCAAGCTGGAGAGTACTACCC CAGGGAAAGGAAGGGCCGAGGAGCCTGTGTTCTCTCTGCCTTCTCCCTTCAAGGCTGCAT ACCAATGGCCCCATCCAGCCGGATGACCTCTCCATTGAGGAATGGGTTCTCGATGATGGC CTGTACGAGGTGAGCATACTCACTAGGGTCACCCACTCCGCTAGGGAAGGGCACTTGGCT GGCCAACAAGTTGCACACTTTCTCTGGGAGGCTGGTCACCAGTGGGGTGCCAAACATACC TAAACAATATACTCACATTCAGAGACTCACCCTTGCTTTCATGACTACCTGGCTCTTCCT TACTTTAACCCTACTTATTGGTGCTACTCTGGGGCCCAAACATTAAACGCTGCCGCTGCT TACGTCGCGGATACCTTATCCTATCACTGCCCATGGCTCGTACTCCCCCTCCCCCTTCAG GTTACAGGCGATCCCCTCACCCCGGCCATGCCCTTCCCCGTTCCCTCTCGACCCCCCTCC CCCTTATGGTCATGCCTGCCCCCCCCCCCCTTCCAATCCTTTCCCTTTGCCCCCCTCCCT TCCCGTCCCCCCCGTTTTGCCCCCCTTCCTTTCCCCCCCCTGCCCGTCCTTCCCTATCCC TCTCCTCCCATCCTCCCACTTCTCCTTCCCGTCCCCATTTCCCTTCTCGTCCTCTTCCGT CCGTCCCGTCCCCCTCCTCCCTCCTTCCCTCCCCTCCCTTTTTCTTTCCCCCCTTTTTTG TTCCCCCCTTCTCCTCCCCTCTCTTCTCCCCCTCCTTCCCCCCCTTCCCCTCTCCCTCTC CCGCTCCCCGCACCCTCTTCCCCTTTTCCCCCCTTTTCCCCCTTTTTCTTCCCCCCCCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004493 |
| Insert Size | 1170 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004493.1, NP_004484.1 |
| RefSeq Size | 990 bp |
| RefSeq ORF | 963 bp |
| Locus ID | 3028 |
| UniProt ID | Q99714 |
| Domains | adh_short |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation |
| Gene Summary | This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201734 | HSD17B10 (Myc-DDK-tagged)-Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 2,400.00 |
|
| RC201734L1 | Lenti ORF clone of Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201734L2 | Lenti ORF clone of Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201734L3 | Lenti ORF clone of Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201734L4 | Lenti ORF clone of Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG201734 | HSD17B10 (tGFP-tagged) - Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 4,000.00 |
|
| SC320588 | HSD17B10 (untagged)-Human hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 2,400.00 |
