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Transglutaminase 2 (TGM2) (NM_004613) Human Untagged Clone
CAT＃: SC117263
TGM2 (untagged)-Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1
CNY 5,040.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | G(h); hTG2; TG(C); TGC; tTG |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117263 sequence for NM_004613 edited (data generated by NextGen Sequencing)
ATGGCCGAGGAGCTGGTCTTAGAGAGGTGTGATCTGGAGCTGGAGACCAATGGCCGAGAC CACCACACGGCCGACCTGTGCCGGGAGAAGCTGGTGGTGCGACGGGGCCAGCCCTTCTGG CTGACCCTGCACTTTGAGGGCCGCAACTACGAGGCCAGTGTAGACAGTCTCACCTTCAGT GTCGTGACCGGCCCAGCCCCTAGCCAGGAGGCCGGGACCAAGGCCCGTTTTCCACTAAGA GATGCTGTGGAGGAGGGTGACTGGACAGCCACCGTGGTGGACCAGCAAGACTGCACCCTC TCGCTGCAGCTCACCACCCCGGCCAACGCCCCCATCGGCCTGTATCGCCTCAGCCTGGAG GCCTCCACTGGCTACCAGGGATCCAGCTTTGTGCTGGGCCACTTCATTTTGCTCTTCAAC GCCTGGTGCCCAGCGGATGCTGTGTACCTGGACTCGGAAGAGGAGCGGCAGGAGTATGTC CTCACCCAGCAGGGCTTTATCTACCAGGGCTCGGCCAAGTTCATCAAGAACATACCTTGG AATTTTGGGCAGTTTGAAGATGGGATCCTAGACATCTGCCTGATCCTTCTAGATGTCAAC CCCAAGTTCCTGAAGAACGCCGGCCGTGACTGCTCCCGCCGCAGCAGCCCCGTCTACGTG GGCCGGGTGGTGAGTGGCATGGTCAACTGCAACGATGACCAGGGTGTGCTGCTGGGACGC TGGGACAACAACTACGGGGACGGCGTCAGCCCCATGTCCTGGATCGGCAGCGTGGACATC CTGCGGCGCTGGAAGAACCACGGCTGCCAGCGCGTCAAGTATGGCCAGTGCTGGGTCTTC GCCGCCGTGGCCTGCACAGTGCTGAGGTGCCTGGGCATCCCTACCCGCGTCGTGACCAAC TACAACTCGGCCCATGACCAGAACAGCAACCTTCTCATCGAGTACTTCCGCAATGAGTTT GGGGAGATCCAGGGTGACAAGAGCGAGATGATCTGGAACTTCCACTGCTGGGTGGAGTCG TGGATGACCAGGCCGGACCTGCAGCCGGGGTACGAGGGCTGGCAGGCCCTGGACCCAACG CCCCAGGAGAAGAGCGAAGGGACGTACTGCTGTGGCCCAGTTCCAGTTCGTGCCATCAAG GAGGGCGACCTGAGCACCAAGTACGATGCGCCCTTTGTCTTTGCGGAGGTCAATGCCGAC GTGGTAGACTGGATCCAGCAGGACGATGGGTCTGTGCACAAATCCATCAACCGTTCCCTG ATCGTTGGGCTGAAGATCAGCACTAAGAGCGTGGGCCGAGACGAGCGGGAGGATATCACC CACACCTACAAATACCCAGAGGGGTCCTCAGAGGAGAGGGAGGCCTTCACAAGGGCGAAC CACCTGAACAAACTGGCCGAGAAGGAGGAGACAGGGATGGCCATGCGGATCCGTGTGGGC CAGAGCATGAACATGGGCAGTGACTTTGACGTCTTTGCCCACATCACCAACAACACCGCT GAGGAGTACGTCTGCCGCCTCCTGCTCTGTGCCCGCACCGTCAGCTACAATGGGATCTTG GGGCCCGAGTGTGGCACCAAGTACCTGCTCAACCTCAACCTGGAGCCTTTCTCTGAGAAG AGCGTTCCTCTTTGCATCCTCTATGAGAAATACCGTGACTGCCTTACGGAGTCCAACCTC ATCAAGGTGCGGGCCCTCCTCGTGGAGCCAGTTATCAACAGCTACCTGCTGGCTGAGAGG GACCTCTACCTGGAGAATCCAGAAATCAAGATCCGGATCCTTGGGGAGCCCAAGCAGAAA CGCAAGCTGGTGGCTGAGGTGTCCCTGCAGAACCCGCTCCCTGTGGCCCTGGAAGGCTGC ACCTTCACTGTGGAGGGGGCCGGCCTGACTGAGGAGCAGAAGACGGTGGAGATCCCAGAC CCCGTGGAGGCAGGGGAGGAAGTTAAGGTGAGAATGGACCTGCTGCCGCTCCACATGGGC CTCCACAAGCTGGTGGTGAACTTCGAGAGCGACAAGCTGAAGGCTGTGAAGGGCTTCCGG AATGTCATCATTGGCCCCGCCTAA Clone variation with respect to NM_004613.2 >OriGene 5' read for NM_004613 unedited
NCCGTTCAGATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACCAGGCCA GTGGTCGCACTTGGAGGGTCTCGCCGCCAGTGGAAGGAGCCACCGCCCCCGCCCGACATG GCCGAGGAGCTGGTCTTAGAGAGGTGTGATCTGGAGCTGGAGACCAATGGCCGAGACCAC CACACGGCCGACCTGTGCCGGGAGAAGCTGGTGGTGCGACGGGGCCAGCCCTTCTGGCTG ACCCTGCACTTTGAGGGCCGCAACTACGAGGCCAGTGTAGACAGTCTCACCTTCAGTGTC GTGACCGGCCCAGCCCCTAGCCAGGAGGCCGGGACCAAGGCCCGTTTTCCACTAAGAGAT GCTGTGGAGGAGGGTGACTGGACAGCCACCGTGGTGGACCAGCAAGACTGCACCCTCTCG CTGCAGCTCACCACCCCGGCCAACGCCCCCATCGGCCTGTATCGCCTCAGCCTGGAGGCC TCCACTGGCTACCAGGGATCCAGCTTTGTGCTGGGCCACTTCATTTTGCTCTTCAACGCC TGGTGCCCAGCGGATGCTGTGTACCTGGACTCGGAAGAGGAGCGGCAGGAGTATGTCCTC ACCCAGCAGGGCTTTATCTACCAGGGCTCGGCCAAGTTCATCAAGAACATACCTTGGAAT TNTGGGCAGTTTGAAGATGGGATCCTAGACATCTGCCTGATCCTTCTANGATGTCAACCC CAGTTCCTGAAGAACGCCGGCCGTGACTGCTCCCGCCGCAGCAGCCCCGTCTACGTGGGC CGGGTGGTGAGTGGCATGGTCAACTGNCACGATGACCANGGTGTGCTGCTGGGACGCTGG GACAACACTACGGGGACGGCGTCAGCCCATGTNCTGGATCGGCAGCGTGGACATCCTGCN GCGCTGGAAGAACACNGCTGCCANCGCGTCAAGTATGGCCAGTGCTGGGNTCTCNNNCGN CGTGCT >OriGene 3' read for NM_004613 unedited
CCATAAACACCTTCTTTTNNGGAGAGGGAGCCATCAGAGTCGAGTTTTTTTTTTTTTTTC TTTTATTTCCGAGTGTGAAAAATAAACTCCCTTTAAATCAGNGNNANGNACCATTGCGGG TCAAAAGCACATCCCTTTGAAAGGNGTGGAACCCAAGGCTTTATATAAAACCAGTAAAGA AATAGAGCTCTATGTATAGAGAAAATATACATGTCTGAAAAATGGGTGACTCTTTCCTGA GCAAAGAAGAAAGATCAAAATGCAACAGAATGATTCTCTCCAAGACCATCCCTGGGAATT GGGAGGCCCTGGAGGCTGTGATCTCTACCTAAAACAGAAAATCCCCAAATCTTTCAGCCT AAGGGAAGCACTGTCAAGTAAAAAGAGCAGGAGATAAAGTTCAAAGCATGACAACTCATG GGATCCACAAGCTACCTCCGGAGCAGGGGCTATGTTTGAAAAGCCTAATACTTGATAGGA ATGGAAAGATGGAAGAGTTAATCTTGTAGGATAAGCGACCAGCACTGATAATATAAAGAA AGATAGGAATAACTTGTCATTAGCAACGAGAAGGATCAAGAGAAGAGAAATGGAAGACAA CGATCAACACACCTATAATTGGAATCCGAAGGAAGAGAACTGAAACAAAAAAAGGAACCG ATTAAAATATTATTAACAAAAAGTGGGAAGCACACAAGTTTAACATCTAATAAAACTATT AAATAAAAAATCGAATAATGTCAGATCAAAAAGTGAAAATTAAATCTATGCACATTTCAA GTGTAAGGTCAAACACAGAACAATACATTACAACTTAATGGAAAAGAATCCTCAAAAAAA GACGAAAACTAACATGCCTATAGTATGAAAAACGAATAAAAATATAAACAATCTCAAAAA CTAAAAAGCTATTAATATTAGTAAAAAAATAAAAAATATATAATCAATAAAAGATCTATA TGAAAAAAATAGATAACTAGAGAAAAACATATATGAATAAAAATTGATATACAGTAAAAA ATAAATATTACATGAATGATTGTACTCATAATCAGAATCTCAAAACTAGAATAAAGAAAA AGTGTATAGAATATTCAATAGAATCAAAATATTACCTAAATATATCACCAAGAATCTTAT ATAATAAGAACACTGAAAATATTTATAAATTATAAGAGATGAGCAGCCTATAAAAACGTG CTCCATTACTCCTTGGTATGAATAACACATATATAGATAATTCTAATAAGATATGCAGCA TAAGCATATCTCGGAAACGACGGAGTGATAATTCATAAAATCACTATATGATTATTAAGA ACTACTGATATATCATAAATAAGGATTCGACTACATGATTATATTGGTATCGTAATCGAT GAGTCAATATGACAACTAATATACGATACATGGAGTCATATTCATATACTGACTTATCAC ACTTACACAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004613 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004613.2, NP_004604.2 |
| RefSeq Size | 3937 bp |
| RefSeq ORF | 2064 bp |
| Locus ID | 7052 |
| UniProt ID | P21980 |
| Domains | Transglutamin_C, TGc |
| Protein Families | Druggable Genome |
| Protein Pathways | Huntington's disease |
| Gene Summary | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Both variants 1 and 5 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Transglutaminase 2 Regulates Self-renewal and Stem Cell Marker of Human Colorectal Cancer Stem Cells.
,null,
Anticancer research
,PubMed ID 29374703
[TGM2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217353 | TGM2 (Myc-DDK-tagged)-Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1 |
CNY 5,032.00 |
|
| RC217353L1 | Lenti ORF clone of Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1, Myc-DDK-tagged |
CNY 7,432.00 |
|
| RC217353L2 | Lenti ORF clone of Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RC217353L3 | Lenti ORF clone of Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC217353L4 | Lenti ORF clone of Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1, mGFP tagged |
CNY 7,432.00 |
|
| RG217353 | TGM2 (tGFP-tagged) - Human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1 |
CNY 6,370.00 |
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